Scaling climate information services and climate smart agriculture through bundled business models by Desire M. Kagabo, Livingstone Byandaga, Patrick Gatsinzi, Patrick Mvuyibwami, Yvonne U. Munyangeri, Nasson Ntwari, Mathieu Ouedraogo

“…Drawing on the synthesis analysis of available relevant publications, we devised a 1–5 scale evaluation framework based on nine scaling readiness indicators—technology, impact, bundling, infrastructure, relevance, evidence, barriers, sustainability, and value addition—to assign scalability scores to 29 business cases with bundled CIS-CSA products and services across Africa and Asia. …”
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Seasonal variations and comparative nutritional composition of hatchery-reared, hatchery-released, and wild black rockfish (Sebastes schlegelii) by Liu Wang, Liu Wang, Yunhai He, Xu Wei, Xinyan Liang, Xinyan Liang, Ruonan Zhang, Ruonan Zhang, Qi Liu, Qi Liu, Chenqi Wang, Chenqi Wang, Jinfeng Chen, Jinfeng Chen, Meiyuan Li, Meiyuan Li, Zhi Ma, Shaodong Qu

“…Stock enhancement has been launched in response to wild populations decline. However, limited evidence is available to confirm the ecological effects after release. …”
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Determinants of infants and young children feeding practices among mothers living in Saudi Arabia: a cross-sectional study by Fatimah Alsada, Tunny Sebastian, Zainab Alzayer, Hawraa Alabbas, Narjis Alhaddad, Hawraa Abu Shahin, Atheer Alghamdi, Haya F. Alhmly, Malek J. Baassiri, Bedour Alkhalifa, Antonina N. Mutoro, Wesam A. Alyahya

“…Abstract Background The WHO sets evidence-based guidelines for infant feeding. Adhering to the WHO guidelines ensures that infants receive the proper nutrition and thus is associated with healthy growth and development. …”
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Findings from the Tushirikiane-4-MH (supporting each other for mental health) mobile health–supported virtual reality randomized controlled trial among urban refugee youth in Kampa... by Carmen H. Logie, Moses Okumu, Zerihun Admassu, Frannie MacKenzie, Lesley Gittings, Jean-Luc Kortenaar, Naimul Khan, Robert Hakiza, Daniel Kibuuka Musoke, Aidah Nakitende, Brenda Katisi, Peter Kyambadde, Richard Lester, Lawrence Mbuagbaw

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B7-H3 CAR-T cell therapy combined with irradiation is effective in targeting bulk and radiation-resistant chordoma cancer cells by Kun Wang, Gianpietro Dotti, Soldano Ferrone, Yufeng Wang, Yin P Hung, Tao Ma, Giulia Cattaneo, Xinhui Wang, David O Osei-Hwedieh, Tara A Walhart, Joseph H Schwab

“…These results provide preclinical evidence for further developing this combinatorial RT and B7-H3 CAR-T cell therapy model in chordoma…”
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Pediatric Tuina for the treatment of functional dyspepsia: A systematic review and meta-analysis of randomized controlled trials by Na-Yeon Ha, Chang-Yul Keum, Jinsung Kim

“…However, addressing identified methodological weaknesses is crucial for future studies to ensure robust evidence.…”
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The Novel Histological Prostatic Inflammation Score Helps Defining the Association Between Stromal and Glandular Inflammation with the Risk of Prostate Cancer at Prostate Biopsy by Ugo Giovanni Falagario, Francesca Sanguedolce, Angelo Cormio, Antonella Ninivaggi, Marco Finati, Francesco Guzzi, Gian Maria Busetto, Carlo Bettocchi, Daniele Castellani, Giuseppe Carrieri, Luigi Cormio

“…<b>Background:</b> There is emerging evidence of an inverse association between prostatic inflammation (PI) and prostate cancer (PCa) diagnosis and outcome. …”
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Advancing treatment choices: CDK4/6 inhibitor switching in HR+/HER2- metastatic breast cancer by Paola Zagami, Angela Esposito, Beatrice Taurelli Salimbeni, Pier Paolo Maria Berton Giachetti, Roberta Scafetta, Matteo Lambertini, Massimo Di Maio, Giuseppe Curigliano, Carmen Criscitiello, Saverio Cinieri

“…Yet, 49 % of respondents emphasized the need for more real world evidence on CDK4/6i switch safety and efficacy. 96 % of respondents reported discontinuation rates between 0% and 25 % of patients, with constipation and hematological toxicity being the most frequent treatment discontinuation reasons. …”
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Genetic characterization of a rare case of pheochromocytoma in a pulmonary transplant patient by Stéfanie Parisien-La Salle, Florence Perreault, Gilles Corbeil, Julie Morisset, Charles Poirier, Catherine Beauregard, Agnès Räkel, Marjorie Labrecque, Martine Tétreault, Martine Tétreault, Christian Cohade, Pasquale Ferraro, Isabelle Bourdeau

“…BackgroundPheochromocytomas (PCCs) and paragangliomas (PGLs) (PPGLs) are rare tumours arising from the chromaffin cells. There is evidence suggesting a link between hypoxemia and PPGLs. …”
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The contrasted impacts of grasshoppers on soil microbial activities in function of primary production and herbivore diet by Ibanez, Sébastien, Foulquier, Arnaud, Brun, Charles, Colace, Marie-Pascale, Piton, Gabin, Bernard, Lionel, Gallet, Christiane, Clément, Jean-Christophe

“…Since these two frameworks can lead to conflicting predictions in some cases, experimental evidence combining herbivore diet and plant productivity is required. …”
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Energetic and genomic potential for hydrogenotrophic, formatotrophic, and acetoclastic methanogenesis in surface-expressed serpentinized fluids of the Samail Ophiolite by Alta E. G. Howells, Alta E. G. Howells, Lilja M. Quinn, Lilja M. Quinn, Miguel G. Silva, Miguel G. Silva, Kylie Akiyama, Kylie Akiyama, Lucas M. Fifer, Lucas M. Fifer, Grayson Boyer, Srishti Kashyap, Kirt Robinson, Kirt Robinson, Jared Broddrick, Everett L. Shock, Tori M. Hoehler

“…We find that formatotrophic methanogenesis affords a higher Affinity (greater energetic yield) than acetoclastic and hydrogenotrophic methanogenesis in pristine serpentinized fluids and, in agreement with previous studies, find genomic evidence for a methanogen of the genus Methanobacterium to carry out formatotrophic and hydrogenotrophic methanogenesis, with the possibility of even using bicarbonate as a supply of CO2. …”
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Long-term smoking contributes to aging frailty and inflammatory response by Huijin Hou, Yidi Chai, Ting Zhang, Yue Liang, Lan Huang, Xu Cao, Shufang Liang

“…Our findings quantitatively link smoking-induced frailty to increased levels of TNF-α and IL-1β, providing experimental evidence for the diagnosis and prevention of frailty in elderly populations. …”
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Establishment and Maintenance of a Digital Therapeutic Alliance in People Living With Negative Symptoms of Schizophrenia: Two Exploratory Single-Arm Studies by Cassandra Snipes, Cornelia Dorner‑Ciossek, Brendan D Hare, Olya Besedina, Tim Campellone, Mariya Petrova, Shaheen E Lakhan, Abhishek Pratap

“… BackgroundEvidence-based digital therapeutics represent a new treatment modality in mental health, potentially providing cost-efficient, accessible means of augmenting existing treatments for chronic mental illnesses. …”
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Enhancing diagnostic outcomes in kidney genetic disorders: the KidGen national kidney genomics study protocol by Amali Mallawaarachchi, Hugh McCarthy, Thomas A. Forbes, Kushani Jayasinghe, Chirag Patel, Stephen I. Alexander, Tiffany Boughtwood, Jeffrey Braithwaite, Aron Chakera, Sam Crafter, Ira W. Deveson, Randall Faull, Trudie Harris, Lilian Johnstone, Matthew Jose, Anna Leaver, Melissa H. Little, Daniel MacArthur, Tessa Mattiske, Christine Mincham, Kathy Nicholls, Catherine Quinlan, Michael C. J. Quinn, Gopala Rangan, Jessica Ryan, Cas Simons, Ian Smyth, Madhivanan Sundaram, Peter Trnka, Laura Wedd, Erik Biros, Zornitza Stark, Andrew Mallett

“…Discussion The KidGen National Kidney Genomics Study is a coordinated, multidisciplinary extension of previous research projects that aims to assess the diagnostic yield of advanced genomic approaches. The study's evidence will drive changes to current diagnostic pathways, including identifying which chronic kidney disease patients are most likely to benefit from a more comprehensive genomic approach to diagnosis.…”
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Phenotypic and genotypic characterization of clinical carbapenem-resistant Acinetobacter species harboring the metallo-beta-lactamases IMP-8 or NDM-1 in China by Qingye Xu, Xinli Mu, Jintao He, Haiyang Liu, Xiaochen Liu, Yanfei Wang, Xiaoting Hua, Yunsong Yu

“…This retrospective analysis serves as a form of “bacterial archaeology,” providing evidence of the evolutionary changes in genetic elements conferring antibiotic resistance.…”
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Mixed-methods evaluation of a behavioural intervention package to identify and amend incorrect penicillin allergy records in UK general practice by Sarah Tonkin-Crine, Robert West, Sinisa Savic, Jonathan Sandoe, Ly-Mee Yu, Sue Pavitt, Ushma Galal, Christopher C Butler, Marta Wanat, Bethany Shinkins, Mina Davoudianfar, Emily Bongard, Sue H Pavitt, Philip Howard, Catherine Porter, Mandy East, Marta Santillo, Louise Savic, Joanne Fielding, Jenny Boards, Catherine E Porter, Jonathan AT Sandoe

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Phase II trial of nab-paclitaxel plus ramucirumab in combination with nivolumab for unresectable advanced or recurrent gastric cancer after progression on first-line treatment incl... by Hidekazu Hirano, Naoki Takahashi, Yusuke Amanuma, Nobumi Suzuki, Daisuke Takahari, Takeshi Kawakami, Chie Kudo-Saito, Kengo Nagashima, Narikazu Boku, Ken Kato, Hirokazu Shoji

“…Abstract Background Patients with advanced gastric cancer (AGC) have poor survival after first-line treatment containing an anti-programmed death-1/ligand 1 (PD-1/PD-L1) antibody. Accumulating evidence suggests rationales for continuing immunotherapy beyond progression, synergistic effects between immune checkpoint inhibitors and angiogenesis inhibitors, and a preferable combination of steroid-free chemotherapy with immunotherapy. …”
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Ambulance attendances involving personality disorder – investigation of crisis-driven re-attendances for mental health, alcohol and other drug, and suicide-related events by JH Broadbear, RP Ogeil, M McGrath, DS Scott, Z Nehme, F Moayeri, D Lubman, S Rao

“…Conclusions: Two-thirds of service users noted to have personality disorder required ambulance services three or more times per year, highlighting the need for evidence-based alternatives to reduce the incidence of mental health crises and reliance on emergency services. …”
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Expression pattern of lncRNA H19 in oral squamous cell carcinoma tissues in comparison to normal tissues. A systematic review by Ramya Sekar, Selvaraj Jayaraman, Saranya Varadarajan, Thodur Madapusi Balaji, Vishnupriya Veeraraghavan, Prabhu Shankar Dayasankar, Dharshini Devi J

“…Nevertheless, its expression patterns in OSCC in contrast to healthy tissues remain unclear. The evidence currently available about H19's expression in OSCC is assessed in this review. …”
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Effect of antioxidant capsule supplementation on oxidative stress markers in hypertensive patients by Novaes-Gaeta Ludmila N., Moraes Mariele C., Katayama Keyla Y., Sangaletti Carine T., Irigoyen Maria Claudia, Freitas Sarah, Viana Ariane, de Angelis Katia, Caldini Elia G., Lopes Heno F.

“…Oxidative stress constitutes an intermediate pathophysiological mechanism for hypertension and cardiovascular disease. Evidence suggests that there is a proportional relationship between diets high in antioxidants and a reduced risk of cardiovascular events. …”
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