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6441
Mediators of Inflammation and Their Effect on Resident Renal Cells: Implications in Lupus Nephritis
Published 2013-01-01“…Expression of IL-6, TNF-α, type I IFNs, and hyaluronan are increased in the kidneys of patients and mice with active lupus nephritis and have been shown to contribute to disease pathogenesis. There is also evidence that despite clinical remission, ongoing inflammatory processes may occur within the glomerular and tubulointerstitial compartments of the kidney, which further promote kidney injury. …”
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6442
Causality Extraction from Medical Text Using Large Language Models (LLMs)
Published 2024-12-01“…Some practical extensions of extracting causal statements from medical text would include providing additional diagnostic support based on less frequent cause–effect relationships, identifying possible inconsistencies in medical guidelines, and evaluating the evidence for recommendations.…”
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6443
An Interstitial 4q Deletion with a Mosaic Complementary Ring Chromosome in a Child with Dysmorphism, Linear Skin Pigmentation, and Hepatomegaly
Published 2017-01-01“…Further microarray studies in the proband using a different microarray platform showed no evidence of mosaicism. This case highlights the importance of an integrated approach to cytogenetic analysis and demonstrates the value of G-banding for detecting mosaicism, as current microarray platforms are unable to detect low level mosaics.…”
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6444
Polyphenol-Protein Complexes and Their Consequences for the Redox Activity, Structure and Function of Honey. A Current View and New Hypothesis – a Review
Published 2015-06-01“…There is increasing evidence that protein complexation by honey polyphenols is changing honey structure and function. …”
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6445
Radiofrequency Ablation for Treatment of Refractory Gastric Antral Vascular Ectasia: A Systematic Review of the Literature
Published 2017-01-01“…The aim of this study is to perform a systematic review of literature in order to assess current evidence supporting the effectiveness of this technique for treatment of refractory GAVE. …”
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6446
Sequence Analysis of How Disability Influenced Life Trajectories in a Past Population from the Nineteenth-Century Sundsvall Region, Sweden
Published 2017-05-01“…To our knowledge this is the first study to employ sequence analysis on a substantially large number of cases to provide demographic evidence of how disability shaped human trajectories in the past during an extended period of life. …”
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6447
What are the impacts of oral complications from cancer therapy on the quality of life of children? A protocol to update a scoping review.
Published 2023-01-01“…Building on a previous review published in 2012, this scoping review aims to identify and map the current evidence base underpinning the oral health-related impacts of cancer treatment on the quality of life of children with cancer.…”
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6448
Local sympathetic nerve depletion does not alter vitiligo progression in a mouse model
Published 2025-01-01“…However, direct experimental evidence for the role of sympathetic nerves in vitiligo development has been lacking. …”
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6449
Judge's Managerial Competences: a Case Study of a High-Performance Court
Published 2024-05-01“…The data was assessed using content analysis, with the support of ATLAS.ti and Iramuteq software. The results evidence eight judges’ managerial competencies and one resource (support team expansion). …”
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6450
Validity, Reliability, and Efficiency of a Standard Goniometer, Medical Inclinometer, and Builder’s Inclinometer
Published 2023-08-01“…Standard patient and inclinometer positioning is recommended to enhance reliability. # Level of Evidence 2…”
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6451
Combined Dexamethasone Suppression-Corticotropin-Releasing Hormone Stimulation Test in Studies of Depression, Alcoholism, and Suicidal Behavior
Published 2006-01-01“…Major depression, alcoholism, and suicidal behavior are public health problems around the world. Considerable evidence suggests that HPA dysregulation is involved in the pathogenesis of depressive disorders, alcoholism, and suicidal behavior. …”
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6452
The politics of gating (A response to Private Security and Public Space by Manzi and Smith-Bowers)
Published 2008-05-01“…I argue that the key ‘problematic’ raised by gated communities is less one of empirical evidence on their impacts, since much work already points to a range of problems, and rather what these developments forecast for the character and dynamics of the urban spaces and societies we wish to live in. …”
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6453
MENTAL BARRIERS TO REDUCE VULNERABILITY TO INJURY DURING A FALL: AN ELEMENTARY ISSUE OF PERSONAL SAFETY IN A GLOBAL CIVILIZATION
Published 2024-10-01“…The cognitive aim of the study was to argue, based on evidence, that radical progress in preventing the consequences of unintentional falls is possible as long as mental barriers are broken down among actors with the potential competence to make changes from the micro to macro scale. …”
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6454
The protective effect and experimental research progress of pleotropic statins in intervertebral disc degeneration
Published 2025-01-01“…With the advancement of research into the pleiotropic effects of statins, an increasing body of evidence suggests their potential as effective therapeutic agents for IVDD. …”
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6455
Stable Agrobacterium-Mediated Transformation of Maritime Pine Based on Kanamycin Selection
Published 2013-01-01“…The highest transformation efficiency (11.4 events per gram of fresh mass) was achieved when a vigorously growing embryonal mass (embryogenic line L01) was cocultivated with Agrobacterium strain AGL1 at the optical density (OD600 nm) of 0.3 for 72 h. Evidence of the stable transgene integration was obtained by polymerase chain reaction for the nptII and uidA genes and expression of the uidA gene. …”
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6456
Biochemical Markers as Predictor of Preterm Labor - and Their Clinical Relevance - the Current Status
Published 2022-12-01“…This paper provides a summary of the current literature on the use of biochemical markers in predicting spontaneous preterm birth in symptomatic and high risk-asymptomatic women. Evidence from the literature suggests cervico vaginal fetal fibronectin,interleukin-6, phosphorylated Insulin-like growth factor binding protein-1(phIGFBP1), placental alpha macroglobulin-1 (PAMG-1) and serum …”
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6457
Applying cognitive diagnostic models to mechanics concept inventories
Published 2025-01-01“…As part of a broader project to develop a cognitive diagnostic assessment for introductory mechanics within an evidence-centered design framework, we identified and tested the student models of four skills that cross content areas in introductory physics: apply vectors, conceptual relationships, algebra, and visualizations. …”
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6458
Investigating the Impact of Digital Leadership Dimensions on Service Economics Dimensions: An Empirical Study of Service Ministries in the Kingdom of Saudi Arabia
Published 2024-10-01“…This study contributes to the current literature by providing empirical evidence on the relationship between digital leadership and service economics. …”
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6459
Can Sensory- and Attachment-Informed Approaches Modify the Perception of Pain? An Experimental Study
Published 2021-01-01“…Accumulating evidence linking pain with both attachment and sensory processing variables introduces the possibility that attachment- and sensory-informed strategies may modify pain experiences. …”
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6460
Asthma in Sickle Cell Disease
Published 2011-01-01“…In recent years, evidence has increased that asthma predisposes to complications of sickle cell disease (SCD), such as pain crises, acute chest syndrome, pulmonary hypertension, and stroke, and is associated with increased mortality. …”
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