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6321
Advanced anaplastic thyroid carcinoma with positive expression of PD-L1 response to immune checkpoint inhibitors: A case report
Published 2025-01-01“…Anaplastic thyroid carcinoma (ATC) is one rare type of thyroid carcinoma without standard systemic treatment for advanced disease. Recent evidence has demonstrated promising efficacy of immune checkpoint inhibitors, particularly those targeting programmed death-1 (PD-1)/programmed death ligand 1 (PD-L1), in a variety of solid tumors. …”
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6322
The Clinical Impact of Vascular Endothelial Growth Factor/Receptor (VEGF/R) Inhibitors on Voice
Published 2023-01-01“…Vascular endothelial growth factor/receptor (VEGF/R) inhibitors are used in chemotherapy protocols to limit tumor angiogenesis. Recent evidence shows they are associated with hoarseness, but their impact on vocal cord function has not been fully identified. …”
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6323
Coordination of care in health systems for users with diabetes and hypertension: a scoping review
Published 2025-01-01“… Objective: to map the available evidence on the characteristics of care coordination between Primary Health Care and Specialized Outpatient Care for users with diabetes and hypertension. …”
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6324
Serum Uric Acid, Alanine Aminotransferase, Hemoglobin and Red Blood Cell Count Levels in Pseudoexfoliation Syndrome
Published 2015-01-01“…The pathogenesis of pseudoexfoliation (PEX), the most common cause of secondary glaucoma, has not been clearly identified, but there is increasing evidence that points out the role of oxidative stress. …”
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6325
Precise Recognition and Feature Depth Analysis of Tennis Training Actions Based on Multimodal Data Integration and Key Action Classification
Published 2025-01-01“…This study provides scientific evidence and technical support for optimizing actions and improving strategies in professional training.…”
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6326
Human parathyroid hormone fragment stimulates the de novo synthesis of prostaglandin endoperoxide synthase in chick calvaria
Published 1993-01-01“…In this communication, evidence is presented that hPTH-(1–34) stimulates the de novo synthesis of PG synthase as demonstrated by the increased activity in calvarial homogenates and microsomes.…”
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6327
Genomic exploration of the journey of Plasmodium vivax in Latin America.
Published 2025-01-01“…Indeed, our analyses suggest that the current American P. vivax populations predominantly stemmed from a now-extinct European lineage, with the potential contribution also from unsampled populations, most likely of West African origin. We also found evidence that P. vivax arrived in Latin America in multiple waves, initially during early European contact and later through post-colonial human migration waves in the late 19th-century. …”
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6328
Early Polytherapy for Probably Benzodiazepine Refractory Naïve Status Epilepticus (Stage 1 Plus)
Published 2025-01-01“…The objective of this review is to provide pathophysiological and pre-clinical evidence, mostly from animal studies, for the different approach of combined polytherapy from the start for those cases of SE falling in the definition of Stage 1 Plus.…”
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6329
Crossing Gender Boundaries: Exploring the Chain-Mediated Causal Role of Social Media Sharing in Shaping Interpersonal Networks and Enhancing Job Satisfaction
Published 2025-01-01“…The findings not only provide new insights into the role of social media in the modern workplace but also offer empirical evidence and practical guidance for organizations on leveraging social media to foster employee relationships and enhance job satisfaction.…”
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6330
Overcoming or overstepping? Boundary infrastructure for learning in the context of continuous improvement research-practice partnership
Published 2025-01-01“…IntroductionUnder federal policy guidelines, school districts are increasingly expected to engage with research evidence to guide their efforts around instructional improvement. …”
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6331
Non-minimal elliptic threefolds at infinite distance II: asymptotic physics
Published 2025-01-01“…Our findings are in agreement with general expectations from quantum gravity and provide further evidence for the Emergent String Conjecture.…”
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6332
Arabidopsis conditional photosynthesis mutants abc1k1 and var2 accumulate partially processed thylakoid preproteins and are defective in chloroplast biogenesis
Published 2025-01-01“…Together the results provide evidence for the requirement of active photosynthesis for processing of photosystem-associated thylakoid proteins and concomitantly progression of chloroplast biogenesis.…”
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6333
The effect of nature-based landscape design on human health and well-being: a thematic synthesis
Published 2025-02-01“…However, there is a lack of review articles discussing specific approaches and factors of landscape design for human well-being in evidence-based landscape research. Therefore, this review aims to explore the research trends and future studies’ direction by adopting a thematic analysis approach. …”
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6334
Intestinal organoids: The path towards clinical application
Published 2025-03-01“…Preclinical studies have demonstrated a remarkable functional recapitulation of infectious and genetic diseases, and there is mounting evidence for the reliability of intestinal organoids as a patient-specific avatar. …”
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6335
The Relationship between Frequently Used Glucose-Lowering Agents and Gut Microbiota in Type 2 Diabetes Mellitus
Published 2018-01-01“…The etiology of diabetes mellitus can be attributed to genetic and/or environmental factors. Current evidence suggests the association of gut microbiota with metabolic diseases. …”
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6336
Assessment and Prognosis Aid Brought on by the Mensurable International Systems for the Attention of Patients Suffering from Neuroictus.
Published 2007-05-01“…But there was evidence that they do not give the prognosis of the disability in a sub stratified way. …”
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6337
Role of intestinal probiotics in the modulation of lipid metabolism: implications for therapeutic treatments
Published 2023-09-01“…Currently, accumulating pieces of evidence indicate that probiotics, living in the gastrointestinal tract, play an important role in regulating host metabolism. …”
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6338
Are Believers Happier than Atheists? Well-being Measures in a Sample of Atheists and Believers in Puerto Rico
Published 2019-01-01“…This study provides empirical evidence to demystify certain traditional assumptions about the supremacy of religious beliefs over secular convictions or vice versa. …”
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6339
Cannabidiol Modulates Neuroinflammatory and Estrogen-Related Pathways in a Sex-Specific Manner in a Chronic Stress Model of Depression
Published 2025-01-01“…Evidence indicates a bidirectional link between depressive symptoms and neuroinflammation. …”
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6340
Parkinson’s disease and exosomes: from pathogenesis to diagnosis and treatment
Published 2021-06-01“…Since the content of the exosomes depends on the cell that secretes them and can change during the progression of the disease, exosome studies can help to understand the pathogenesis and control the course of the disease. There is growing evidence of the importance of exosomes for cell-to-cell communication, mediating the exchange of biological information and substances, and the ability to cross the blood-brain barrier. …”
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