PPARγ as a Novel Therapeutic Target in Lung Cancer by Aravind T. Reddy, Sowmya P. Lakshmi, Raju C. Reddy

“…Its involvement in adipocyte differentiation and glucose and lipid homeostasis is well-recognized, but accumulating evidence now suggests that PPARγ may also function as a tumor suppressor, inhibiting development of primary tumors and metastases in lung cancer and other malignancies. …”
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The Pathology of T Cells in Systemic Lupus Erythematosus by Anselm Mak, Nien Yee Kow

“…Thus, the condition was traditionally classified as a “B-cell disease”. Compelling evidence has however shown that without the assistance of the helper T lymphocytes, it is indeed difficult for the “helpless” B cells to become functional enough to trigger SLE-related inflammation. …”
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Plant-Derived Anti-Inflammatory Compounds: Hopes and Disappointments regarding the Translation of Preclinical Knowledge into Clinical Progress by Robert Fürst, Ilse Zündorf

“…The major obstacle in this field is the translation of preclinical knowledge into evidence-based clinical progress. Human trials of good quality are often missing or, when available, are frequently not suitable to really prove a therapeutical value. …”
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Group counseling using motivational interviewing technique: reducing students' academic procrastination by Sulistiyana Sulistiyana, Mufida Istati, Engga Nur Rahmah

“…Implications The results of this study provide evidence thatmotivational interviewing can have an effective effect on reducing academic procrastination in students and can be used as a conceptual and practical reference in the development of future counseling.…”
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Maritime Pilots’ Risky Operational Behavior Analysis Based on Structural Equation Model by Tingliu Xu, Yingjie Xiao, Zhuohong Jiang

“…In addition, with empirical evidence for pilotage safety intervention in China, this measurement can also provide scheduling and management decision support for Chinese maritime pilot stations.…”
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How is digitalization influencing transformative learning in sports and nursing? : Systematic Review by Tri Johan Agus Yuswanto, Fitriana Kurniasari Solikhah, Naya Ernawati

“…Specifically, the review evaluates the effectiveness of digital interventions in improving learning outcomes, synthesizes existing evidence on the integration of digital skills in nursing education and the application of digital technologies in sports medicine, and identifies gaps or limitations in the current literature. …”
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Enhancing integrated reporting quality through boardroom diversity: the critical role of board diligence in the petroleum industry by Ally Adam Mshana, Siasa Issa Mzenzi, Said Juma Suluo

“…This research contributes to stakeholder theory by providing empirical evidence supporting the role of board diversity and diligence in shaping corporate reporting practices. …”
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Role of Low FODMAP Diet and Probiotics on Gut Microbiome in Irritable Bowel Syndrome (IBS) by Shabnam Mohajir Selvaraj, Sunny Hei Wong, Hooi-Leng Ser, Learn-Han Lee

“…Existing literature suggest that IBS patients are dysbiotic as evidence indicates decreased levels of Bifidobacteria, Bacteroidetes and Faecalibacterium prausnitzii and increased levels of Firmicutes in comparison to healthy individuals. …”
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Percutaneous Fixation of Anterior Column Acetabular Fracture in a Renal Transplant Recipient by Halil Ceylan, Ozgur Selek, Ahmet Y. Sarlak

“…The patient was treated with percutaneous fixation techniques and at one year of postoperative period there was no evidence of degenerative signs and the clinical outcome was good. …”
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Capnography and the Bispectral Index—Their Role in Pediatric Sedation: A Brief Review by Maria Sammartino, Barbara Volpe, Fabio Sbaraglia, Rossella Garra, Alessandro D'Addessi

“…The use of the BIS index, however, needs further investigation due to a lack of evidence, especially in infants. In this paper, we will investigate the role of capnography and the BIS index in improving monitoring standards in pediatric sedation.…”
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The Prevalence of Concha Bullosa and Nasal Septal Deviation and Their Relationship to Maxillary Sinusitis by Volumetric Tomography by Kyle D. Smith, Paul C. Edwards, Tarnjit S. Saini, Neil S. Norton

“…The objective of this study was to determine the prevalence of concha bullosa and nasal septal deviation and their potential relationships to maxillary sinusitis. 883 CT scans taken at Creighton University School of Dentistry from 2005 to 2008 were retrospectively reviewed for the presence of concha bullosa, nasal septal deviation, and maxillary sinusitis. 67.5% of patients exhibited pneumatization of at least one concha, 19.4% of patients had a deviated septum, and 50.0% had mucosal thickening consistent with maxillary sinusitis. 49.3% of patients who had concha bullosa also had evidence of maxillary sinusitis. Only 19.5% of patients with concha bullosa also had nasal septal deviation, whereas 19.7% of patients with sinusitis also presented with nasal septal deviation. …”
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Disturbance of Inorganic Phosphate Metabolism in Diabetes Mellitus: Its Relevance to the Pathogenesis of Diabetic Retinopathy by H. Vorum, J. Ditzel

“…Any interruption of optimal ATP production might lead to cell injury and possible cell death, and evidence will be provided herein that such cell death does occur in diabetic retinopathy. …”
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Obesity as a Major Risk Factor for Cancer by Giovanni De Pergola, Franco Silvestris

“…Reports from the International Agency for Research into Cancer and the World Cancer Research Fund (WCRF) have shown that the strongest evidence exists for an association of obesity with the following cancer types: endometrial, esophageal adenocarcinoma, colorectal, postmenopausal breast, prostate, and renal, whereas the less common malignancies are leukemia, non-Hodgkin’s lymphoma, multiple myeloma, malignant melanoma, and thyroid tumours. …”
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Is Valproate Depressogenic in Patients Remitting from Acute Mania? Case Series by Kamini Vasudev, Priya Sharma

“…Valproate is an effective antimanic agent and is recommended as a first-line medication in the treatment of acute mania. Current evidence based guidelines recommend that valproate should be given as a loading dose as it produces a rapid antimanic and antipsychotic response with minimal side-effects. …”
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Knowing, doing and showing: a framework for evidencing education and learning designers’ practice in higher education by Jennifer Boreland, Tanya Henry, Sue Sharpe

“…With that premise in mind, the purpose of this paper is to outline a possible Framework for designers to measure and evidence their competence and contributions either to use for future engagements and collaborations, to show impact of their practice on quality learning and teaching, to intentionally plan for design engagements, and/or to support applications for promotion or career progression. …”
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A Classification of Basic Helix-Loop-Helix Transcription Factors of Soybean by Karen A. Hudson, Matthew E. Hudson

“…These were classified with respect to their predicted DNA binding potential, intron/exon structure, and the phylogeny of the bHLH domain. Evidence is presented that the vast majority (281) of these 319 soybean bHLH genes are expressed at the mRNA level. …”
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Is the Dog a Possible Reservoir for Cutaneous Leishmaniasis in Suriname? by Alida Kent, Prakash Ramkalup, Dennis Mans, Henk Schallig

“…The clinical, serological, and molecular data show some preliminary lines of evidence that canine leishmaniosis is present in Suriname, but further studies are needed to incriminate the reservoir, including a possible sylvatic cycle.…”
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Administrative Detention: Compliance of the Code of Ukraine on Administrative Offenses with Social Needs and the Current State of Keeping Human Rights and Freedoms by M. A. Sambor

“…The author has studied administrative detention as a measure to ensure proceedings in cases on administrative offenses, its use in documenting administrative offenses and interdependent measures, as well as the use of data obtained as evidence in proceedings in cases on administrative offenses. …”
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Progesterone and Bone: Actions Promoting Bone Health in Women by Vanadin Seifert-Klauss, Jerilynn C. Prior

“…Estradiol (E2) and progesterone (P4) collaborate within bone remodelling on resorption (E2) and formation (P4). We integrate evidence that P4 may prevent and, with antiresorptives, treat women's osteoporosis. …”
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Type 2 Diabetes, PUFAs, and Vitamin D: Their Relation to Inflammation by Ana L. Guadarrama-López, Roxana Valdés-Ramos, Beatríz E. Martínez-Carrillo

“…On the other hand, there is evidence about the beneficial effect of polyunsaturated fatty acids (PUFA) n-3 and n-6 in patients with chronic inflammatory diseases including diabetes. …”
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