CytoSorb® Hemoadsorption as a Promising Tool to Handle COVID-19-Induced Cytokine Storm by Alice-Christin Acevedo, Michael Zoller, Christina Scharf, Uwe Liebchen, Michael Irlbeck, Ines Schroeder

“…Accumulating evidence suggests that a patient subgroup with severe COVID-19 develops a cytokine release syndrome leading to capillary leakage and organ injury. …”
Get full text

Bisphenol A and Metabolic Syndrome: Results from NHANES by Srinivas Teppala, Suresh Madhavan, Anoop Shankar

“…Bisphenol A (BPA) is detected in the urine of >95% of US adults. Recent evidence from population-based studies suggests that BPA is associated with individual components for metabolic syndrome (MetS). …”
Get full text

The Role of Soft Skills in Mediating the Relationship between Risk Management Competency and Work Readiness by Zuhrohtun Zuhrohtun, Kunti Sunaryo, Sri Astuti, Heri Susanto

“…This study provides empirical evidence that only process risk management can affect soft skills but cannot directly affect student job readiness but process risk management competencies can affect student job readiness if mediated by soft skills. …”
Get full text

Phases I–III Clinical Trials Using Adult Stem Cells by Ricardo Sanz-Ruiz, Enrique Gutiérrez Ibañes, Adolfo Villa Arranz, María Eugenia Fernández Santos, Pedro L. Sánchez Fernández, Francisco Fernández-Avilés

“…In this paper we will examine the evidence available, analyze the main phase I and II randomized clinical trials and their limitations, discuss the key points in the design of future trials, and depict new directions of research in this fascinating field.…”
Get full text

COLLATERAL DETERMINATS IN BANK RISK MANANAGEMENT: THE REGIONAL CASE by A. M. Karminsky, O. D. Khon

“…This article presents LTV (loan-to-value) as a major collateral determinant. The empirical evidence of interlinkage between collateral requirements, by the means of LTV, and risk premium is provided for loan portfolio of Russian regional banks. …”
Get full text

Factors Constraining Subject Expression in European Portuguese Spoken in Hamburg. A Bi-Generational Corpus Investigation by Cristina Flores, Esther Rinke

“…The results do not reveal evidence in favour of ongoing language change, given that there are neither quantitative nor qualitative differences between the two generations of speakers. …”
Get full text

Outcomes of Patients Transferred to Tertiary Center by Life-Saving System in Saudi Arabia. A Propensity Score Matching Observational Study by Soliman Mohammed, Alenzi Hanan, Alfenaikh Rehab, Aletreby Ahmed, Alenzi Malak, Alenzi Hend, Gano Jennifer, Alrashed Rana, Altaymani Yasmeen, Al-Odat Mohammed, Aletreby Waleed

“…However, an empirical gap exists in available evidence, as outcomes of transferred patients to higher centers are inconsistent.…”
Get full text

Update on Peripheral Arterial Vasodilation, Ascites and Hepatorenal Syndrome in Cirrhosis by Mladen Knotek, Boris Rogachev, Robert W Schrier

“…In cirrhosis of the liver, according to the peripheral arterial vasodilation hypothesis, relative underfilling of the arterial tree triggers a neurohumoral response (activation of renin-angiotensinaldosterone system, sympathetic nervous system, nonosmotic release of vasopressin) aimed at restoring circulatory integrity by promoting renal sodium and water retention. Evidence has accumulated for a major role of increased vascular production of nitric oxide as the primary cause of arterial vasodilation in cirrhosis. …”
Get full text

Impact of High-Rise Buildings Construction Process on Adjacent Tunnels by Haifeng Guo, Aijun Yao, Jiantao Zhang, Yijun Zhou, Yanfei Guo

“…The results can provide evidence for the further study on the impact of adjacent construction process on the tunnels.…”
Get full text

Gastric Pneumatosis in the Setting of Diabetic Ketoacidosis by Mohammed Rifat Shaik, Chet Ranabhat, Nishat Anjum Shaik, Akshay Duddu, Zaid Bilgrami, Guofeng Xie

“…Initial evaluation revealed elevated blood glucose levels, an anion gap metabolic acidosis, and evidence of gastric pneumatosis on imaging. The patient was managed with aggressive fluid resuscitation and intravenous insulin therapy per diabetic ketoacidosis protocol. …”
Get full text

ENDOSCOPY IN LUMBAR ADJACENT LEVEL DISEASE - SYSTEMATIC REVIEW AND META-ANALYSIS by PEDRO FELLIPE DEBORTO RUDINE REMOLLI EVANGELISTA, ABGAIL GOMES SILVA, FELIPE DONATANGELO, LINA MARCIA DE ARAUJO HERVAL

“…However, higher-quality studies are needed to visualize the real impact of the technique on the treatment of adjacent-level pathologies. Level of Evidence I; Systematic Revision and Metanalysis.…”
Get full text

Die buitebladkunswerk by Maritha Snyman

“….), publishers still have a final veto on covers. There is ample evidence however a cover design must, from a semiotic point of view, be regarded as an iconic complement to the linguistic text. …”
Get full text

Molecular Mechanisms Underlying Hypothermia-Induced Neuroprotection by Yasushi Shintani, Yasuko Terao, Hiroyuki Ohta

“…There is now compelling clinical evidence that prolonged, moderate cerebral hypothermia initiated within a few hours after severe ischemia can reduce subsequent neuronal death and improve behavioral recovery. …”
Get full text

GABAergic neurons in basal forebrain exert frequency-specific modulation on auditory cortex and enhance attentional selection of auditory stimuli by Kevin Thomas, Hamid Azimi, Davide Maggioni, Mark Sanders, Pilar Vaca Sánchez, Michael A. Harvey, Gregor Rainer

“…We found that GABAergic BF modulation impacted target detection specifically close to perceptual threshold, consistent with a role in attentional modulation. We also present evidence for target frequency specificity of this modulation, including frequency selectivity and tonotopic organization of pNB/GP, as well as frequency band specific effects of optogenetics on behavioural target detection and on neural activity in auditory cortex and thalamus. …”
Get full text

Harnessing artificial intelligence for enhanced nanoparticle design in precision oncology by Mujibullah Sheikh, Pranita S. Jirvankar

“…Additionally, we present evidence suggesting that AI-designed nanoparticles have the potential to be environmentally sustainable alternatives in cancer therapy. …”
Get full text

New U-Pb zircon data for Maarianvaara granite and Tohmajärvi volcanic complex, eastern Finland: geologic implications by Asko Kontinen, Jarmo Kohonen, Perttu Mikkola, Matti Kurhila

“…Thus, burial of organic carbon in the sedimentary protoliths of the Tohmajärvi succession was evidently occurring at ca. 2.11 Ga, about 50 Ma earlier than has been assumed in some recent time-stratigraphic interpretations.…”
Get full text

Lessons learnt from advocating for family medicine in South Africa by Robert J. Mash, Klaus Von Pressentin, Jenny Nash, Tasleem Ras

“…This short report reflects on the lessons learnt in terms of seven key principles for advocacy with government: understand the issue, identify the right audience, build relationships, use evidence and data, craft a clear message, engage the public, and use the media.…”
Get full text

Strategies to Enhance Mesenchymal Stem Cell-Based Therapies for Acute Respiratory Distress Syndrome by Jibin Han, Yanmin Li, Yuanyuan Li

“…To provide a comprehensive and updated view, we summarize a large body of experimental evidence for a variety of strategies directed towards strengthening the therapeutic potential of MSCs in ARDS.…”
Get full text

Spontaneous Adrenal Hemorrhage with Mild Hypoadrenalism in a Patient Anticoagulated with Apixaban for Antiphospholipid Syndrome: A Case Report and Literature Review by Jia Wei Tan, Anant Shukla, Jiun-Ruey Hu, Sachin K. Majumdar

“…After 8 months of follow-up, he remained on cortisol replacement with no evidence of recovery. We reviewed PubMed/MEDLINE indexed articles from 1950 to 2022 for cases of AH in APLS patients on anticoagulation. …”
Get full text

Tumor-Like Reaction to Polypropylene Mesh from a Mid-Urethral Sling Material Resembling Giant Cell Tumor of Vagina by Ali Azadi, James A. Bradley, Dennis M. O’Connor, Amir Azadi, Donald R. Ostergard

“…There are few reports regarding its carcinogenic potential. There is lack of evidence supporting tumor formation directly attributed to the use of polypropylene material. …”
Get full text