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5261
The Role of Noncoding RNA in Airway Allergic Diseases through Regulation of T Cell Subsets
Published 2022-01-01“…The human body is frequently exposed to allergens and environmental irritants that trigger immune and inflammatory responses, resulting in altered gene expression. Mounting evidence suggested that epigenetic alterations were strongly associated with the progression and severity of allergic diseases. …”
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5262
Activation Mechanism of LRRK2 and Its Cellular Functions in Parkinson’s Disease
Published 2016-01-01“…Here, we review the recent progress in elucidating the complex LRRK2 activation mechanism, describe the accumulating evidence that link LRRK2-mediated PD to mitochondrial dysfunction and aberrant autophagy, and discuss possible ways for therapeutically targeting LRRK2.…”
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5263
The Microbiome in Connective Tissue Diseases and Vasculitides: An Updated Narrative Review
Published 2017-01-01“…Results. We found some evidence that dysbiosis participates in the pathogenesis of systemic lupus erythematosus, systemic sclerosis, Sjögren’s syndrome, and Behçet’s disease, but there are still few data concerning the role of dysbiosis in other CTDs or vasculitides. …”
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5264
Antimicrobial Activities of Stigmasterol from Piper crocatum In Vitro and In Silico
Published 2024-01-01“…The high incidence of oral health issues and antibiotic resistance has stimulated research into discovering novel antimicrobial drugs. Prior evidence suggests that red betel leaves (Piper crocatum Ruiz and Pav) possess potential antimicrobial properties, including the presence of stigmasterol, a bioactive compound. …”
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5265
Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids, with Cranial and Caudal Extension
Published 2017-01-01“…MRI examination of the brain and spinal cord showed evidence of faint bright signal intensity foci in T2/FLAIR involving bilateral cerebral hemispheres, subcortical deep white matter, bilateral thalami, posterior pons and left brachium pontis, and basal ganglia, with small nodular enhancement that aligned along curvilinear structures; those lesions also were apparent along the spinal cord at multiple levels. …”
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5266
Intramuscular (Infiltrating) Lipoma of the Floor of the Mouth
Published 2018-01-01“…No lipoblasts, atypical cells, or high mitotic index were found. There was no evidence of recurrence two years postoperatively. Review of the literature yielded that IML occurring in the sublingual region is extremely rare.…”
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5267
A Rare Case of Cardiac Recovery after Acute Myocarditis from West Nile Virus Infection: A Review of the Current Literature
Published 2022-01-01“…He was intubated and was placed on vasoactive pressors for supportive care due to evidence of mixed cardiogenic and septic shock. After two weeks of hemodynamic support, we discovered a near-complete cardiac recovery, as shown on a repeat transthoracic echocardiography (TTE) and a normalized mean arterial blood pressure. …”
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5268
The Transnational Construction and Maintenance of Digital Feminist Media Activism: Engagement Practices in the Global South and North
Published 2025-01-01“…The methodology is based on in-depth interviews with actors who participate to different degrees in the composition of the world (of feminist me-dia activism) - content producers, support teams, and audiences - and direct observation of the practices developed by participants in these spaces to enable a multi-site comparison and provide transnational evidence of the ways in which digital feminist media work.…”
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5269
Emotion dysregulation, performance concerns, and mental health among Canadian athletes
Published 2025-01-01“…There is some initial evidence that difficulties in emotion regulation are positively associated with depression, anxiety, and stress among university student-athletes; however, research on emotion dysregulation in sport contexts is limited. …”
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5270
Entecavir: stability and drug-excipient compatibility
Published 2025-01-01“…The thermal analysis of marketed solid dosage forms revealed a predominance of the lactose monohydrate profile at the expense of ETV and other inputs in the TGA and DTA curves, due to its high content in the formulations; this makes the evidence of ETV-lactose chemical interaction even more important. …”
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5271
Strategic analysis of hardships and opportunities for developing urban tourism(Pilot study: shahr-e-kord)
Published 2017-12-01“…His study is a descriptive-analytic one and was done using filed studies and data gathered through evidence and libraries, questionnaires (considering the attitude of 70 officials and tourists) and Internet. …”
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5272
A Rare Occurrence of Isolated Brain Metastases from Gastric Cancer
Published 2019-01-01“…Further evaluation of these symptoms led to the discovery of three metastatic brain lesions without evidence of extracranial metastases. Conclusions. Our review of the literature has found that such cases are rare. …”
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5273
Semi-Idealized Study on Estimation of Partly and Fully Space Varying Open Boundary Conditions for Tidal Models
Published 2013-01-01“…This work provides a concrete evidence that ill-posedness of inverse problem can generate wrong parameter inversion results and produce an unreal “good data fitting.”…”
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5274
Controversies in the Surgical Management of Spinal Cord Injuries
Published 2012-01-01“…Future prospective collection of outcome data that would suffice as evidence-based is recommended and necessary.…”
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5275
Factors Influencing Decision-Making for Poststroke Paretic Upper Limb Treatment: A Survey of Japanese Physical and Occupational Therapists
Published 2024-01-01“…This study revealed that evidence about treatment (very strong: n=171 (27.0%), and strong: n=287 (45.0%)) and patient preferences (very strong: n=203 (31.8%), and strong: n=251 (39.3%)) affected decision-making significantly regarding treatment methods for the poststroke paretic upper limb.…”
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5276
The future of physiological research: A greater understanding of female master athletes and aging?
Published 2024-11-01“…It highlights the importance of studying female master athletes to better understand the aging process and offers recommendations to address current evidence gaps. The need for more comprehensive mechanistic data on highly trained older women, novel cataloguing and analysis of real‐world datasets, case studies/series, and longitudinal research are also emphasized. …”
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5277
Human Immunodeficiency Virus Infection in Pregnancy
Published 1998-01-01“…Vertical transmission of HIV can occur in utero, intrapartum and postpartum, but current evidence suggests that the majority of transmission occurs toward end of term, or during labour and delivery. …”
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5278
The Unity of Space in Kant’s Pre-Critical Philosophy
Published 2022-03-01“…But considerable textual evidence shows that Kant continues to aver the theory throughout the 1770s and 1780s in the looser epistemic context of his lectures. …”
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5279
Ortega on liberalism and democracy: revisiting an old discussion
Published 2025-01-01“…Finaly, I discuss the hypotheses of the existence of a third phase in Ortega’s liberalism, more pessimistic and conservative, of which evidence can be found in his essay On the Romam Empire. …”
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5280
Clinical and economic burden of varicella in pediatric patients hospitalized in four institutions in Guatemala.
Published 2025-01-01“…Varicella presents a public health challenge in Guatemala, with limited evidence regarding its impact; vaccine is currently absent from the national immunization program. …”
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