Three new asexual Kirschsteiniothelia species from Guizhou Province, China by Xing-Juan Xiao, Ning-Guo Liu, Jian Ma, Li-Juan Zhang, Dan-Feng Bao, Song Bai, Fatimah Al-Otibi, Kevin D. Hyde, Yong-Zhong Lu

“…Based on distinct morphological characteristics and molecular phylogenetic evidence, we describe three new species: Kirschsteiniothelia guizhouensis, K. weiningensis, and K. xishuiensis. …”
Get full text

Disruption in the Blood-Brain Barrier: The Missing Link between Brain and Body Inflammation in Bipolar Disorder? by Jay P. Patel, Benicio N. Frey

“…There has been growing evidence that BBB disruption is associated with brain inflammatory conditions such as Alzheimer’s disease and multiple sclerosis. …”
Get full text

S-Amlodipine: An Isomer with Difference—Time to Shift from Racemic Amlodipine by Jamshed Dalal, J. C. Mohan, S. S. Iyengar, Jagdish Hiremath, Immaneni Sathyamurthy, Sandeep Bansal, Dhiman Kahali, Arup Dasbiswas

“…This review discusses clinical evidence from total 42 studies (26 randomized controlled trials, 14 observational studies, and 2 meta-analyses) corroborating over 7400 patients treated with S-AM. …”
Get full text

Protective Role of the ACE2/Ang-(1–9) Axis in Cardiovascular Remodeling by María Paz Ocaranza, Jorge E. Jalil

“…We review here the current experimental evidence suggesting that activation of the ACE2/Ang-(1–9) axis protects the heart and vessels (and possibly the kidney) from adverse cardiovascular remodeling in hypertension as well as in heart failure.…”
Get full text

Role of Acetylsalicylic Acid in Cytokine Stimulation of Macrophages in Antibody-Dependent Cellular Cytotoxicity (ADCC) by M. Jäpel, H. Lötzerich, K. Rogalla

“…In addition to the spectrum of biological action already known to be exhibited by acetylsalicylic acid (ASA) as an analgesic, anti-inflammatory and platelet aggregation inhibitor, there is growing evidence of a stimulatory effect on the immune system. …”
Get full text

Alcohol Use Disorder and the Gut–Brain Axis: A Narrative Review of the Role of Gut Microbiota and Implications for Treatment by Shikha Shukla, Cynthia L. Hsu

“…Finally, we review the current evidence on gut microbial-directed therapies for AUD and discuss the implications of this research for our understanding of the pathophysiology of AUD and future research directions.…”
Get full text

Hybrid Model for Stock Market Volatility by Kofi Agyarko, Nana Kena Frempong, Eric Neebo Wiah

“…Empirical evidence suggests that the traditional GARCH-type models are unable to accurately estimate the volatility of financial markets. …”
Get full text

Pas de Deux: Active Ulcerative Colitis in an HIV-Positive Patient by David C Pearson, Lloyd R Sutherland, Stephan Urbanski

“…Repeat colonoscopy disclosed pancolitis and biopsies did not show evidence of cytomegalovirus infection. He has not had an acquired immune deficiency syndrome-defining illness. …”
Get full text

Transcriptional Regulation of the p53 Tumor Suppressor Gene in S-Phase of the Cell-Cycle and the Cellular Response to DNA Damage by David Reisman, Paula Takahashi, Amanda Polson, Kristy Boggs

“…Numerous studies have demonstrated that p53 transcription is activated before or during early S-phase in cells progressing from G0/G1 into S-phase through the combined action of two DNA-binding factors RBP-Jκ and C/EBPβ-2. Here, we review evidence that this induction occurs to provide available p53 mRNA in order to prepare the cell for DNA damage in S-phase, this ensuring a rapid response to DNA damage before exiting this stage of the cell cycle.…”
Get full text

The Role and Potential Pathogenic Mechanism of Particulate Matter in Childhood Asthma: A Review and Perspective by Xuchen Xu, Jianing Zhang, Xin Yang, Yuanyuan Zhang, Zhimin Chen

“…Asthma, the most common chronic respiratory disease in children, affects numerous people worldwide. Accumulating evidence suggests that exposure to high levels of particulate matter (PM), either acutely or chronically, is associated with the exacerbation and incidence of pediatric asthma. …”
Get full text

Modulation of Fibrosis in Systemic Sclerosis by Nitric Oxide and Antioxidants by Audrey Dooley, K. Richard Bruckdorfer, David J. Abraham

“…One of the most important and early modulators of disease activity is thought to be oxidative stress. Evidence suggests that the free radical nitric oxide (NO), a key mediator of oxidative stress, can profoundly influence the early microvasculopathy, and possibly the ensuing fibrogenic response. …”
Get full text

Heterogeneous Chromosomal Aberrations in Intraductal Breast Lesions Adjacent to Invasive Carcinoma by Michaela Aubele, Margaret Cummings, Axel Walch, Horst Zitzelsberger, Jörg Nährig, Heinz Höfler, Martin Werner

“…There is evidence that breast cancer is a heterogeneous disease phenotypically as well as molecular biologically. …”
Get full text

Noise-sensitive measure for stochastic resonance in biological oscillators by Ying-Cheng Lai, Kwangho Park

“…There has been ample experimental evidence that a variety ofbiological systems use the mechanism of stochastic resonance for tasks suchas prey capture and sensory information processing. …”
Get full text

Endoscopic Vein Harvesting for Coronary Bypass Grafting: A Blessing or a Trojan Horse? by Ryan Accord, Jos Maessen

“…However, in 2009 convincing evidence of inferior histological graft properties became available. …”
Get full text

The role of oligopolies and economic groups in accelerating inflation in recent Argentina by Pablo Manzanelli, Leandro Amoretti

“…This, among other possible factors, has allowed those branches to increase their profit margins as their prices rose in excess of the prices of imported inputs and the rest of wholesale prices, and of their wage costs. This evidence not only connects with the international debate about the characteristics of inflationary processes in core countries but it is also a contribution, albeit a preliminary one, that addresses the stickiness of the Argentine economy when it comes to decelerating the rise in prices after an “initial impetus”.…”
Get full text

Sleep Paralysis and Hallucinosis by Gregory Stores

“…Review provided no convincing evidence of various other sleep disorders nor physical conditions in which hallucinatory experiences can occur. …”
Get full text

Motion – Helicobacter pylori Causes or Worsens GERD: Arguments against the Motion by Kenneth EL McColl

“…A third smaller study, which seemed to demonstrate that persistent infection was associated with GERD, was flawed, in that the two treatment groups were not comparable. The evidence thus does not support the idea that H pylori infection provokes or aggravates GERD.…”
Get full text

Effects of melatonin on planaria head regeneration are dependent on both timing and duration of exposure by Simon C. Beeching, Hanna E. Ruland, Katelyn M. Sparks

“…Our results demonstrate that P. gracilis is capable of recovery from the melatonin‐induced delay of regeneration and reveal the time required to recover to control levels. Further, we found evidence of regenerative stage‐specific responses to discontinuous melatonin exposure, including non‐inhibitory effects. …”
Get full text

A Case of Brainstem Anesthesia after Retrobulbar Block for Globe Rupture Repair by Tavish Nanda, Lisa Ross, Gregory Kerr

“…To present a rare case of brainstem anesthesia from retrobulbar block and discuss evidence-based methods for reducing the incidence of this complication. …”
Get full text

Achromobacter xylosoxidans Relapsing Peritonitis and Streptococcus suis Peritonitis in Peritoneal Dialysis Patients: A Report of Two Cases by Rafał Donderski, Magdalena Grajewska, Agnieszka Mikucka, Beata Sulikowska, Eugenia Gospodarek-Komkowska, Jacek Manitius

“…Achromobacter xylosoxidans (A. xylosoxidans) and Streptococcus suis (S. suis) are rare pathogens, but there is emerging evidence that they may be also responsible for PD related peritonitis. …”
Get full text