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4581
miR-16-1 Promotes the Aberrant α-Synuclein Accumulation in Parkinson Disease via Targeting Heat Shock Protein 70
Published 2014-01-01“…There is striking evidence that heat shock protein 70 (Hsp70) negatively regulates α-synuclein aggregation, which plays a significant role in the formation and progression of Parkinson disease (PD). …”
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4582
Libraries in society: comparing international metrics of societal progress to library usage statistics
Published 2023-12-01“…The objective of this research is to determine if countries with higher metrics related to the Sustainable Development Goals also demonstrate evidence of stronger relationships between library usage and literacy. …”
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4583
Psychosocial Interventions for Elderly People with Bipolar Disorder: Systematic Review with Meta-Analysis
Published 2025-01-01“…The objective of this study was to analyse the evidence of the effectiveness of psychosocial and Cognitive-Behavioral Therapy-based interventions for bipolar disorder. …”
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4584
Bank Credit and Loan Repayment Rates during COVID-19 in Kabale District, Uganda
Published 2023“…This means that there is evidence that the distribution of mean scores for each of the three variables is not the same depending on the borrower's ability to repay. …”
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4585
Factors Affecting the Teaching of English Language in Secondary Schools in Buhara Sub-County.
Published 2024“…The study's objectives were to identify the specific challenges teachers face in effectively teaching English, examine how these challenges affect students' learning outcomes and overall English proficiency, and propose evidence-based strategies to address these challenges and enhance the teaching and learning of English in secondary schools in Buhara Sub-County. …”
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4586
Gender and performance disparity in mathematics: A study of South Western Uganda
Published 2020“…Such assumptions commonly fronted inadvertently without considering possible negative consequences, are based on societal construction of social differences with no substantive evidence as demonstrated in this study.…”
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4587
CD36 enrichment in HER2-positive mesenchymal stem cells drives therapy refractoriness in breast cancer
Published 2025-01-01“…Abstract Background Growing evidence shows that the reprogramming of fatty acid (FA) metabolism plays a key role in HER2-positive (HER2 +) breast cancer (BC) aggressiveness, therapy resistance and cancer stemness. …”
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4588
Variability of plankton communities in relation to the lunar cycle in oceanic waters
Published 2025-02-01“…Among these few studies, there is compelling evidence of a lunar cycle of epipelagic zooplankton biomass in subtropical waters during the late winter bloom. …”
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4589
The institutionalisation of research and innovation in Swiss sports federations – Analysis of the status quo
Published 2025-01-01“…While one federation has shown evidence in five out of six categories, most federations only show activity in 1-3 categories. …”
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4590
Driving effect of P16 methylation on telomerase reverse transcriptase-mediated immortalization and transformation of normal human fibroblasts
Published 2025-02-01“…This study aimed to provide experimental evidence that P16 methylation directly drives cancer development. …”
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4591
Case report: Successful treatment of hyperbaric oxygen for radiation-induced hemorrhagic cystitis in a 95-year-old patient with bladder cancer
Published 2025-02-01“…High-quality clinical evidence exists regarding the impact of hyperbaric oxygen therapy (HBOT) on RHC. …”
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4592
Resident-based learning model for sustainable resident participation in municipal solid waste management program
Published 2021-10-01“…The survey provided evidence that the education program has succeeded in forming new habits for residents. …”
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4593
Comparative Lipid-Lowering/Increasing Efficacy of 7 Statins in Patients with Dyslipidemia, Cardiovascular Diseases, or Diabetes Mellitus: Systematic Review and Network Meta-Analyse...
Published 2020-01-01“…The drug efficacy may differ among different statins, and evidence from head-to-head comparisons is sparse and inconsistent. …”
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4594
Microgeographical Variation in <i>Dirofilaria immitis</i> Prevalence in Dogs in Suburban and Urban Areas of Rio De Janeiro, Brazil
Published 2024-12-01“…This study reinforces the evidence that the prevalence of <i>D. immitis</i> is increasing in areas previously considered to have low prevalence or to be non-endemic. …”
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4595
Malignant Bowel Obstruction in Advanced Gynecologic Cancers: An Updated Review from a Multidisciplinary Perspective
Published 2018-01-01“…Prospective data are needed to inform clinical practice, establish a new benchmark for evidence-based MBO management, and better understand the biology of MBO.…”
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4596
Giardiose et oesophagostomose nodulaire au parc national de Taï : risque zoonotique ?
Published 2016-01-01“…L’examen microscopique des selles a permis de mettre en évidence des kystes de Giardia sp. dans 9 % des échantillons humains et dans 16 % des prélèvements de singes. …”
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4597
Comparative effectiveness of urine drug screening strategies alongside opioid agonist treatment in British Columbia, Canada: a population-based observational study protocol
Published 2023-05-01“…However, there is limited evidence supporting the utility of mandatory UDTs—particularly the impact of UDT frequency on OAT retention. …”
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4598
Evolution du comportement de manipulation chez les strepsirrhiniens
Published 2016-01-01“…Une importante variabilité dans les types de saisies utilisés, incluant des stratégies longtemps décrites comme spécifiques des humains, a ainsi été mise en évidence. Cependant, bien que la préhension soit impliquée dans de nombreuses activités chez tous les primates, elle reste peu étudiée chez les platyrrhiniens et les strepsirrhiniens. …”
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4599
The articular wrist complex in Miocene and Plio-Pleistocene African hominoids: anatomofunctional and morphometric comparative approach
Published 2009-12-01“…L’analyse morphométrique géométrique tridimensionnelle a mis en évidence que la conformation de chacun des os était liée i) soit aux différents types de saisie de force pratiquées par les anthropoïdes, ii) soit à leur comportement de suspension et de quadrupédie. …”
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4600