Emerging Roles of Immune Cells in Postoperative Cognitive Dysfunction by Yue Liu, Yiqing Yin

“…Postoperative cognitive dysfunction (POCD), a long-lasting cognitive decline after surgery, is currently a major clinical problem with no clear pathophysiological mechanism or effective therapy. Accumulating evidence suggests that neuroinflammation plays a critical role in POCD. …”
Get full text

New Public Management and its Implementation in the CEE Region: What do we know and where do we go? by Juraj Nemec

“…But governing by predictable, reliable and coherent, open and transparent, accountable and responsible bureaucracy, using evidence and consultation based policy making and simultaneously properly managing efficiency, economy and effectiveness of any government operation is the future target.…”
Get full text

Developing and Validating a User-Friendly Quality Benchmark: Enhancing the Integrity of Online Health Information for Patients and Clinicians by Lubna Daraz PhD, Cicek Dogu MA

“…This article briefly outlines the development and validation of an evidence-based online health information evaluation tool. …”
Get full text

Immunopeptidomics for autoimmunity: unlocking the chamber of immune secrets by Sanya Arshad, Benjamin Cameron, Alok V. Joglekar

“…Especially, immunopeptidomics has provided key evidence to explain the genetic risk posed by HLA alleles. …”
Get full text

Two ways to one goal: new strategy of antiviral therapy for chronic hepatitis C by S. N. Batskikh

“…Taking into account an apparent positive effect of induction phase for boceprevir modes of treatment and absence of that evidence for telaprevir application, both new antiviral strategies are justified for clinical application in CHC patients.…”
Get full text

The interaction of nanostructured antimicrobials with biological systems: Cellular uptake, trafficking and potential toxicity by Adriano Brandelli

“…Nanoparticles can enter the organism by oral, dermal and inhalation routes and distributed to different tissues by the circulatory system. Increasing evidence indicate that targeting to specific tissues, cellular uptake and intracellular fate of nanoparticles are strongly influenced by size, shape and surface properties. …”
Get full text

Exploring the influence of copper precursors and solvents on catalyst performance in the hydrogenation of hydroxyacetone to 1,2-Propanediol by Martina Cazzolaro, Jia Yang, De Chen

“…The presence of Cu+ ions in the samples was investigated by CO chemisorption, N2O reactive frontal chromatography and XPS. However, no evidence of its impact on the activity was established.…”
Get full text

Nonlinear Optical Imaging to Evaluate the Impact of Obesity on Mammary Gland and Tumor Stroma by Thuc T. Le, Charles W. Rehrer, Terry B. Huff, Maxine B. Nichols, Ignacio G. Camarillo, Ji-Xin Cheng

“…Given the importance of mammary stroma to the growth and migration of tumor cells, our observation provides the first imaging evidence that supports the relationship between obesity and breast cancer risk.…”
Get full text

Intravenous Lormetazepam during Sedation Weaning in a 26-Year-Old Critically Ill Woman by Alawi Luetz, Bjoern Weiss, Claudia D. Spies

“…Recent evidence revealed that sedation is related to adverse outcomes including a higher mortality. …”
Get full text

Host Cell Autophagy in Immune Response to Zoonotic Infections by Panagiotis Skendros, Ioannis Mitroulis

“…Autophagy is a fundamental homeostatic process in which cytoplasmic targets are sequestered within double-membraned autophagosomes and subsequently delivered to lysosomes for degradation. Accumulating evidence supports the pivotal role of autophagy in host defense against intracellular pathogens implicating both innate and adaptive immunity. …”
Get full text

Wenckebach Block due to Hyperkalemia: A Case Report by Aparajita Sohoni, Berenice Perez, Amandeep Singh

“…The patient's symptoms and electrocardiogram (ECG) evidence of Wenckebach block resolved with lowering of serum potassium levels, with subsequent ECG showing first-degree AV block. …”
Get full text

Modeling the role of fish population in mitigating algal bloom by Mohammad Sajid, Arvind Kumar Misra, Ahmed S. Almohaimeed

“…To validate our analytical findings, we have conducted numerical simulations, which provided robust evidence for the resilience of the ecosystem under different scenarios.…”
Get full text

Hyperbaric Oxygen Therapy of an Adolescent Stem Cell Transplantation Recipient with Hemorrhagic Cystitis and BK Virus by David López, Abdullah Alismail, Laren D. Tan

“…The findings of this case support and shows that there is growing evidence for the use of HBOT as adjunctive therapy for patients with BK virus associated with HC after stem cell transplantation.…”
Get full text

Modeling Spatial Riding Characteristics of Bike-Sharing Users Using Hotspot Areas-Based Association Rule Mining by Chao Sun, Jian Lu

“…These findings make us understand urban spatial structure in response to traffic plan and provide evidence for bike-sharing dispatch optimization.…”
Get full text

Border Region Between Poland and Germany: Strengthened by the COVID-19 Pandemic by Steffen Fleßa, Julia Kuntosch

“…However, this virus is also a tremendous economic challenge. There is some evidence that vulnerable groups and regions are in particular at risk of suffering from unemployment, insolvency and other economic hardships during the pandemic. …”
Get full text

Unique Cytokine Signature in the Plasma of Patients with Fibromyalgia by Jamie Sturgill, Elizabeth McGee, Victoria Menzies

“…The TH2 suppression provides strong evidence of immune dysregulation in patients with FMS.…”
Get full text

Les habitants : acteurs du développement dans les projets de mise en tourisme ? Cas du Parc National de Loango au Gabon  by Ariane Payen

“…Cet article met en évidence que le manque de communication entre acteurs et l’insuffisance de prise en compte des réalités socio-anthropologiques d’un territoire, peuvent conduire à l’échec d’un projet de tourisme communautaire dans les aires protégées. …”
Get full text

N.R. Ayupova by N.R. Ayupova

“…Paleozoic siliceous-ferruginous oxide sedimentary rocks of the Urals massive sulfide deposits contain well-preserved textural and structural evidence indicating the role of microorganisms in their formation. …”
Get full text

Habitat and Spatio-Temporal Interaction Between Green Peafowl with Cattle and Megaherbivores in Baluran National Park by Satyawan Pudyatmoko

“…The pattern of interaction between green peafowl and domesticated cattle was similar to those of between green peafowl and the majority of wild mammal. There was no evidence of negative impact of domesticated cattle on the spatial occurrence as well as temporal activity of green peafowl. …”
Get full text

Application of Intracellular Alkaline Phosphatase Activity Measurement in Detection of Neutrophil Adherence In Vitro by Katarzyna Bednarska, Magdalena Klink, Zofia Sulowska

“…We have proposed the use of the fluorimetric method with 4-methylumbelliferyl phosphate (4-MUP) specific substrate for the alkaline phosphatase determination in the neutrophil adhesion assay. We provide evidence that the endogenous neutrophil alkaline phosphatase (NAP) activity evaluation is reliable to quantify neutrophil adhesion at a wide range of cell numbers (104–106). …”
Get full text