Protein-bound uremic toxins as therapeutic targets for cardiovascular, kidney, and metabolic disorders by Shihan Zhang, Shasha Tang, Yalei Liu, Binghua Xue, Qinyuan Xie, Lingyun Zhao, Huijuan Yuan

“…Traditional approaches to managing CKM syndrome risk are inadequate in these patients, necessitating strategies targeting specific CKM syndrome risk factors. Increasing evidence suggests that addressing uremic toxins and/or pathways induced by uremic toxins may reduce CKM syndrome risk and treat the disease. …”
Get full text

Large Traumatic Pneumatocele in a 2-Year-Old Child by N. K. Cheung, A. James, R. Kumar

“…This case adds further evidence to the current literature that significantly large traumatic pneumatoceles with failure of initial conservative management warrant surgical exploration and management to optimise recovery and prevent complications.…”
Get full text

Epiploic Appendagitis Mimicking Recurrent Diverticulitis by R. Plummer, Y. Sekigami, Lilian Chen, James Yoo

“…However, a subsequent CT scan revealed epiploic appendagitis with no evidence of diverticulitis. Though uncommon, in patients with a history of recurrent diverticulitis, alternative causes of left lower quadrant abdominal pain such as epiploic appendagitis should be considered as this may alter future treatment decisions.…”
Get full text

Macrolide Use in the Treatment of Critically Ill Patients with Pneumonia: Incidence, Correlates, Timing and Outcomes by Wendy I Sligl, Holly Hoang, Dean T Eurich, Atul Malhotra, Thomas J Marrie, Sumit R Majumdar

“…BACKGROUND: Macrolide antibiotics are commonly used to treat pneumonia despite increasing antimicrobial resistance. Evidence suggests that macrolides may also decrease mortality in severe sepsis via immunomodulatory properties.…”
Get full text

Use of Methadone for Neuropathic Pain by Dwight Moulin

“…Anticonvulsant and antidepressant treatments provide effective analgesia in up to 50% of patients with chronic neuropathic pain (2) and there is a growing body of high-quality evidence that controlled-release opioid analgesics provide substantial pain relief in a further subset of patients (3-6). …”
Get full text

Mitochondrial Heterogeneity: Evaluating Mitochondrial Subpopulation Dynamics in Stem Cells by D. C. Woods

“…Although traditionally viewed as the “powerhouse” of the cell, an accruing body of evidence in the rapidly growing field of mitochondrial biology supports additional roles of mitochondria as key participants in a multitude of cellular functions. …”
Get full text

Climate change and its impact on infectious diseases in Asia by Amanda Zain, Sapna P Sadarangani, Lynette Pei-Chi Shek, Shawn Vasoo

“…In this narrative review, we outline the evidence of the impact of climate change on infectious diseases of importance in Asia, including vector-borne diseases, food- and water-borne diseases, antimicrobial resistance and other infectious diseases. …”
Get full text

Unilateral Temporal Lobe Damage and the Partial Kluver–Bucy Syndrome by G. D. L. Bates, S. G. Sturman

“…Her case thereby meets criteria for the partial syndrome but without evidence of bilateral damage. The discussion covers the various presentations of hyperphagia, the significance of the symptom cluster of Kluver–Bucy syndrome and the management difficulties presented by hyperphagia.…”
Get full text

Could postbiotics improve mental health? by Aziz Homayouni-Rad, Jalil Houshyar, Hossein Alikhah, Saba Kamalledin Moghadam, Zohreh Osouli, Vahideh Sarabi-Aghdam, Alireza Asghari

Get full text

Stève Bernardin, La fabrique privée d’un problème public. La sécurité routière entre industriels et assureurs aux États-Unis (années 1920 à 2000) by Stève Bernardin

“…Some put the emphasis on scientific evidence to insist on vehicle safety, while others refer to moral arguments related to drivers’ behaviour. …”
Get full text

Current Concepts of Immunology and Diagnosis in Amniotic Fluid Embolism by Michael D. Benson

“…Anaphylaxis appears to be doubtful while the available evidence supports a role for complement activation. …”
Get full text

Some Problems in Proving the Existence of the Universal Common Ancestor of Life on Earth by Takahiro Yonezawa, Masami Hasegawa

“…Although overwhelming circumstantial evidence supports the existence of the universal common ancestor of all extant life on Earth, it is still an open question whether the universal common ancestor existed or not. …”
Get full text

The psychological focus of white house press secretaries during scandal: A case study of the Obama and Trump administrations by Ely Maxwell, Markowitz David Matthew

“…That is, press secretaries had a more negative tone during each scandal compared to before each scandal. Contrary to prior evidence, time after scandal was not associated with a reduction in self-focus, and press secretary language patterns were largely not moderated by administration (nor their goals). …”
Get full text

Revisiting Estrogen: Efficacy and Safety for Postmenopausal Bone Health by Sandra M. Sacco, Wendy E. Ward

“…The aim of this paper is to continue the dialogue regarding the benefits and controversies of HT with the goal of encouraging the dissemination of-up-to date evidence that may influence how HT is viewed and prescribed.…”
Get full text

Revision Arthroplasty in the Haemophiliac Patient by A. P. Molloy, B. J. O'Neill, L. Molloy, B. White, H. Smyth, T. Mc. Carthy

“…Despite this there is little evidence in the literature regarding revision arthroplasty in this cohort of patients. …”
Get full text

THE HISTORICAL DEVELOPMENT AND CURRENT TRENDS OF POLITICAL SCIENCE AS A FIELD OF STUDY IN NIGERIA by Toye Manuwa

“…It assesses how political science relates to other disciplines and to public policy by providing analytical tools and empirical evidence for understanding and addressing political issues and problems. …”
Get full text

Oral Health and Hygiene Content in Nursing Fundamentals Textbooks by Rita A. Jablonski

“…Best mouth care practices included evidence-based and consensus-based practices as published primarily by the American Dental Association and supported by both published nursing research and review articles specific to mouth care and published dental research and review articles specific to mouth care. …”
Get full text

The impact of obesity: a narrative review by Benjamin Chih Chiang Lam, Amanda Yuan Ling Lim, Soo Ling Chan, Mabel Po Shan Yum, Natalie Si Ya Koh, Eric Andrew Finkelstein

“…In summary, obesity is strongly related to >50 medical conditions, with many of them having evidence from Mendelian randomisation studies to support causality. …”
Get full text

Complex Interplay of Eastern Bloc SMEs Trade Credit Determinants: Changes due to the Global Financial Crisis by Tamara Teplova, Tatiana Sokolova, Kristina Galenskaya, Mariya Gubareva

“…The GFC has changed this complex relationship. We evidence that, after the GFC, equity concentration and state subsidies have a positive effect.…”
Get full text

O diferencial do empreendedorismo solidário by Luiz Inácio Gaiger, Andressa da Silva Corrêa

“…The article aims to bring evidence that the solidarity economic undertakings, based on voluntary association, productive cooperation and self-management, employ a unique rationality, different from the capitalistic one. …”
Get full text