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11261
Galactin-8 DNA methylation mediates macrophage autophagy through the MAPK/mTOR pathway to alleviate atherosclerosis
Published 2025-01-01“…Previous studies have shown that Galectin-8 (GAL8) DNA methylation level is associated with sudden death of coronary heart disease or acute events of coronary heart disease. However, the mechanism of GAL8 DNA methylation and gene expression in AS has not been elucidated, prompting us to carry out further research on it. …”
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11262
A phase 2, double-blind, placebo-controlled trial of a valproate/lithium combination in ALS patients
Published 2025-01-01“…Major changes in the ALSFRS-R score were observed, including a decrease of 1.195 points/month in the placebo group (95% CI: 0.7869–1.6031) and of 0.5085 under VPA-Li treatment (95% CI: 0.2288–0.7882) between months 6 and 14. Adverse events included bad mouth taste, constipation, and anorexia. …”
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11263
A phase 2, double-blind, placebo-controlled trial of a valproate/lithium combination in ALS patients
Published 2025-01-01“…Major changes in the ALSFRS-R score were observed, including a decrease of 1.195 points/month in the placebo group (95% CI: 0.7869–1.6031) and of 0.5085 under VPA-Li treatment (95% CI: 0.2288–0.7882) between months 6 and 14. Adverse events included bad mouth taste, constipation, and anorexia. …”
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11264
Development of a comprehensive model to predict stock prices in the stock market with an interpretive structural modeling approach
Published 2024-06-01“…Multiple factors, such as market dynamics, industry trends, company performance, economic conditions, political events, and globalization, exert influence on stock markets. …”
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11265
Bridge Employment Model of Qualified Employees in Iran's Public Organizations
Published 2024-12-01“…For nearly thirty years, retirement has been discussed not as a momentary event but as a process. The presented model can be a basis for planning organizations to reuse the experiences, knowledge, expertise and skills of retirees in professional and non-professional jobs. …”
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11266
Research on Characteristics and Influencing Factors of High Temperature Disaster Risk in Wuhan Based on Local Climate Zone
Published 2025-01-01“…ObjectiveAgainst the background of rapid urbanization and global warming, Wuhan is frequently hit by extreme heat events, which not only poses a serious threat to the health status of local residents, but also brings great losses to socio-economic development. …”
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11267
“Restoration of the Past Scenery-Realm”: A Research on the Scenery-Realm Restoration of Jiang’s Fu Garden During Qing Dynasty in the Historical Revolution of the Humble Administrat...
Published 2025-02-01“…It is therefore evident that the Humble Administrator’s Garden, which has retained its reputation and is still considered to partially maintain its original design intent and forms after hundreds of years, merits further research on its restoration events. The Jiang’s Fu Garden play a prominent role in the historical narratives of the Humble Administrator’s Garden during Qing Dynasty. …”
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11268
Podophyllotoxin mediates hepatic toxicity via the C5a/C5aR/ROS/NLRP3 and cGMP/PKG/mTOR axis in rats based on toxicological evidence chain (TEC) concept by phosphoproteomic analysis
Published 2025-01-01“…This approach involves a tiered search for evidence of Harmful Ingredients Evidence (HIE), Injury Phenotype Evidence (IPE), Adverse Outcomes Evidence (AOE), and Toxic Events Evidence (TEE) during the development of PPT-induced hepatotoxicity, thereby constructing a guiding toxicology evidence chain. …”
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11269
HSTC: hybrid traffic scheduling mechanism in time-sensitive networking
Published 2022-06-01“…However, in actual industrial network, there is still a small number of burst traffic triggered by events. Burst traffic has no fixed parameters but has an important impact on the normal operation of the system. …”
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11270
Analysis of Verena Klemm's Portrayal of the Personality of Hazrat Fatima (PBUH)
Published 2024-03-01“…As Hazrat Fatima (PBUH) holds special respect and dignity in the beliefs of Muslims, both Shiite and Sunni, analyzing Klemm's article is necessary to avoid creating a series of unbalanced depictions of her personality and to explain the facts.Materials and MethodsContent analysis is used as the method of research to categorize events with common characteristics under the title of a concept and then classify them into different domains and characteristics. …”
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11271
Fálétí’s Philosophical Sensibility
Published 2021-12-01“…Essays 60 Adeshina Afolayan In fact, the publication of Fágúnwà’s Ògbójù Ọdẹ Nínú Igbó Ìrúnmalẹ (The ̀ Intrepid Hunter in the Forest of Spirits, 1938) made the chronology of literary events in Africa, and it misses out Fálétí’s 1965 work. …”
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11272
Editorial
Published 2022-04-01“…An unprecedented pandemic calls for an unprecedented reaction and therefore IGJR 1/2021 and 2/2021 are special issues that deal with this disruptive event. We have invited several health experts, politicians and scholars alike to share their perspectives in short opinion pieces (instead of regular peer-reviewed articles). …”
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11273
BRICS expansion in the news coverage of member countries: a political economy perspective
Published 2025-02-01“…All newspapers emphasize the importance of the BRICS Summit as a key event in global geopolitics. For instance, they discuss the 2023 BRICS Summit in South Africa as a focal point for member countries to discuss various global issues. …”
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11274
Recruiting Young People for Digital Mental Health Research: Lessons From an AI-Driven Adaptive Trial
Published 2025-01-01“…To recruit participants, paid social media advertising on Facebook and Instagram was used, alongside mailing lists of university networks and student organizations or services, media releases, announcements during classes and events, study posters or flyers on university campuses, and health professional networks. …”
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11275
Authority and Moral Conflicts in the Films of Adébáyọ Fálétí: Àfọ̀njá, Gáà, Ṣawo Ṣẹ̀gbẹ̀rì and the Yorùbá Cosmopolis
Published 2021-12-01“…While Àfọ̀njá and Gáà are historical drama based on actual events in the history of the Yorùbá Empire, Ṣawo Ṣegberi is purely fictional and is based on a postcolonial Nigerian setting. …”
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11276
Child mortality in England after national lockdowns for COVID-19: An analysis of childhood deaths, 2019-2023.
Published 2025-01-01“…In contrast, rate of death after Intrapartum events increased across the first period, followed by a decrease in rate in the second (Period 1 IRR 1.15 (95% CI 1.00-1.34)) versus Period 2 (IRR 0.78 (95% CI 0.68-0.91), pdifference = 0.004). …”
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11277
Pegilated interferon alpha 2b «Pegaltevir» chronic hepatitis C treatment (randomized clinical trial)
Published 2018-08-01“…Pegaltevir® and PegIntron® treatment groups were comparable safety profile, adverse events were expected, mainly of mild and moderate severity. …”
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11278
Farmers’ climate change perception, impacts and adaptation strategies in response to drought in the Northwest area of Bangladesh
Published 2025-04-01“…It is well known that the prospect and occurrence of such catastrophes is a significant impediment to progress and the improvement of human welfare.The frequency and the severity of extreme weather events due to climate change in South East Asia including Bangladesh is anticipated to intensify in the forthcoming years. …”
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11279
A Meta-Synthesis of the Integrated Model of Customer Value co-Destruction and Value co-Creation
Published 2024-12-01“…These companies have repeatedly tried to create value for customers using various technologies, but this has caused them to encounter numerous problems and even turn the aforementioned activity into an anti-brand event for them. In this regard, it should be borne in mind that both value creation and value destruction are two inseparable aspects of the cooperation processes between the organization and the customer, and there is a thin line between the two. …”
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11280
Intersemiotic Translation: From Medieval Poetry to Modern Movie
Published 2024-12-01“…Discussion of Results and Conclusion Since the narrative has manifested in the form of a movie, it naturally incorporates elements of imagination and dramatic aspects. Some events, actions, reactions, and themes are repeated in the screenplay by the filmmaker, while others have been altered in terms of the storyline and contemporary culture, and some parts have been creatively added to the script. …”
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