Genetic counselling in the era of next generation sequencing by Diego Espada-Musitu, África Manero-Azua, Yerai Vado, Guiomar Perez de Nanclares

“…The clinical application of NGS has raised many challenges in genetic counselling for families in terms of the interpretation of test results and incidental findings, as well as technical limitations in the event of inconclusive results. Given the impact of genetic results in clinical decision-making, specialized knowledge is required of the techniques and methods used in genetic studies, their advantages and limitations, and their potential psychosocial, legal and ethical impact on patients, relatives and health care professionals. …”
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Machine and deep learning algorithms for sentiment analysis during COVID-19: A vision to create fake news resistant society. by Muhammad Tayyab Zamir, Fida Ullah, Rasikh Tariq, Waqas Haider Bangyal, Muhammad Arif, Alexander Gelbukh

“…Individuals commonly engage in expressing their viewpoints regarding contemporary events, hence presenting a significant difficulty for scholars to categorize the sentiment associated with such expressions effectively. …”
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Neurocognitive Function, Psychosocial Outcome, and Health-Related Quality of Life of the First-Generation Metastatic Melanoma Survivors Treated with Ipilimumab by Anne Rogiers, Christophe Leys, Justine Lauwyck, Adrian Schembri, Gil Awada, Julia Katharina Schwarze, Jennifer De Cremer, Peter Theuns, Paul Maruff, Mark De Ridder, Jan L. Bernheim, Bart Neyns

“…To assess neurocognitive function (NCF), psychosocial outcome, health-related quality of life (HRQoL), and long-term effects of immune-related adverse events (irAE) on metastatic melanoma survivors treated with ipilimumab (IPI). …”
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Perancangan Pengalaman Pengguna Portal Job Fair Sarjana Sakti dengan Pendekatan Human-Centered Design by Annisah Amalia, Herman Tolle, Ratih Kartika Dewi

“…Job fair, which is an offline event, has been canceled to reduce the spread of COVID-19 virus. …”
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Association of the Monocyte to High-Density Lipoprotein Cholesterol Ratio and Neutrophil to High-Density Lipoprotein Cholesterol Ratio With the Severity of New-Onset Coronary Arter... by Shu H, Han S, Qiu W, Li J, Zhang X, Su H, Wu H, Zhao G, Li Q

“…Previous studies have found that MHR and NHR are associated with the risk of cardiovascular and cerebrovascular events and death. However, the correlation between MHR, NHR, and the severity of newly diagnosed coronary artery disease (CAD) has not been thoroughly explored.Methods: In this retrospective study, we enrolled 1489 patients who underwent coronary angiography for the first time between January 2022 and December 2023, of which 1143 were diagnosed with CAD. …”
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Pegloticase and Methotrexate Cotherapy in Patients With Uncontrolled Gout With Prior Pegloticase Monotherapy Failure: Findings of an Open‐Label Trial by Orrin M. Troum, John K. Botson, Katie Obermeyer, Bo Chao, Yang Song, Jennifer Zarzoso, Kjerstina Gutierrez, Supra Verma, Lissa Padnick‐Silver, Brian LaMoreaux

“…Safety was assessed via adverse events (AEs) and laboratory monitoring. Results Eleven patients began pegloticase plus MTX treatment (91% male patients, mean age 58.6 ± 11.3 years, mean ± SD SU levels 8.5 ± 3.2 mg/dL, 91% tophaceous). …”
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Machine learning models for dementia screening to classify brain amyloid positivity on positron emission tomography using blood markers and demographic characteristics: a retrospec... by Noriyuki Kimura, Kotaro Sasaki, Teruaki Masuda, Takuya Ataka, Mariko Matsumoto, Mika Kitamura, Yosuke Nakamura, Etsuro Matsubara

“…Abstract Background Intracerebral amyloid β (Aβ) accumulation is considered the initial observable event in the pathological process of Alzheimer’s disease (AD). …”
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The Effects of Presenting AI Uncertainty Information on Pharmacists’ Trust in Automated Pill Recognition Technology: Exploratory Mixed Subjects Study by Jin Yong Kim, Vincent D Marshall, Brigid Rowell, Qiyuan Chen, Yifan Zheng, John D Lee, Raed Al Kontar, Corey Lester, Xi Jessie Yang

“… BackgroundDispensing errors significantly contribute to adverse drug events, resulting in substantial health care costs and patient harm. …”
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Insights into ozone pollution control in urban areas by decoupling meteorological factors based on machine learning by Y. Qiu, X. Li, X. Li, W. Chai, Y. Liu, M. Song, X. Tian, Q. Zou, W. Lou, W. Zhang, J. Li, Y. Zhang

“…The sensitivity of O<span class="inline-formula">₃</span> formation shifted towards the transition regime between VOC- and NO<span class="inline-formula">_<i>x</i></span>-limited regimes during the O<span class="inline-formula">₃</span> pollution event. Vehicle exhaust became the primary source of VOC emissions after “removing” the effect of dispersion, contributing 41.8 % to VOCs during the pollution periods. …”
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Predictive factors' modeling of entrepreneurial opportunities in international companies by Ali Farahani, Younos Vakil Alroaia, Farideh Haghshenaskashani, Ali Faez

“…Causal conditions were placed in the form of seven categories: unexpected events, changes based on industry and market structure, shortage based on methods, contradictory situation, change based on values and knowledge, new knowledge, and demographic characteristics; and the four main categories were selected include organizational strategies, market related strategies, business strategies, and effective performance management. …”
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Geoconservation in Latin America and the Caribbean by Maria Da Gloria Motta Garcia, Marcos Antonio Leite Do Nascimento

“…In the book “Patrimonio geológico y su conservación en América Latina: Situación y perspectivas nacionales” (in English, “Geological heritage and its conservation in Latin America: National situation and perspectives”), Palacio-Prieto et al. (2016) make a panorama of the state-of-the-art of geoconservation in the region, as well as a synthesis of the key events that contributed to the current status. …”
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The Concept of Rebellion/Rebel in the Behistun Inscription: Formal Terminology and Phrases by Adel Allahyari, Assistant Professor Hossein Badamchi

“…During this campaign, he captured and punished 9 rebel leaders. Following these events, Darius commissioned the creation of the Behistun Inscription and its relief to assert his legitimacy, detailing the reasons and methods of his ascension to the Achaemenid throne. …”
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Evaluation of Arabic lesson teaching in higher education based on the Kirkpatrick model by Ali Akbar Mollaie, Mohammad Aslam Raiesi

“…Among these issues in time and simultaneity, it can be mentioned historical, social, geographical, cultural (religion, language and customs) events. ), economic, political, scientific and technological and the like; each of which can be among the constituents of national identity. …”
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Designing a cyber insurance implementation model using foundational data theory by Behzad Esmaeilifar, manouchehr Ansari

“…Cyber insurance focuses on covering losses and negative events caused by electronic risks against possible risks such as "theft of cash", and it can examine losses caused by business interruption (Wanchun et al, 2018), and It also examines the types of events or conditions that may prevent the organization from reaching its goals (Rezakhani & Dadbeh, 2021). ​…”
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Cognitive decline in relation to later-life high temperature exposure in a Chinese nationwide cohort by Yu-Qian Huang, Lian-Sheng Zhang, Ji-Xing Yang, Fang Wang, Ya-Qi Wang, Li-Feng Zhu, Yuan-Yuan Zhang, Bo-Ning Deng, Qian-Qian Xiang, Yun-Quan Zhang

“…Growing evidence has linked extreme temperature with neuropsychiatric disorders under climate warming with frequent extreme heat events over the past decades, while cognitive performance in relation to heat exposure remains largely unstudied, particularly in populations at high vulnerability to climate risks (e.g., China). …”
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SHoes for Adolescent PatEllofemoral pain: study protocol for the SHAPE Australian community-based, randomised clinical trial by Kim L Bennell, Kade L Paterson, Rana S Hinman, Jo-Anne Manski-Nankervis, Adam Bryant, Karen Elaine Lamb, Peixuan Li, Sam Shearer, Anurika P De Silva

“…Other measures include cointervention use, adherence, adverse events, shoe comfort, descriptive characteristics, physical activity levels, footwear characteristics and objective foot measures.Ethics and dissemination This study has been approved by the University of Melbourne Greater than Low Risk Human Research Ethics Committee (reference: 2022-25470-35344-4). …”
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Real-life study on the effectiveness and safety of sofosbuvir/velpatasvir-based antiviral agents for hepatitis C eradication in Chinese patients by Jiayi Wang, Lingyao Du, Dongmei Zhang, Chen Zhou, Yilan Zeng, Miao Liu, Xing Cheng, Xiaona Song, Han Chen, Ning Han, Enqiang Chen, Hong Tang

“…The primary efficacy endpoint was sustained virological response at post-treatment week 12 (SVR12). Adverse events (AEs) were evaluated during treatment. Results: The study included 483 patients with HCV genotypes 1, 2, 3, 6 and uncertain ones. …”
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Interventions for the management of post-COVID-19 condition (long COVID): protocol for a living systematic review and network meta-analysis by Paul Garner, Lawrence Mbuagbaw, Jason W Busse, Dena Zeraatkar, Thomas Agoritsas, Ariel Izcovich, Tari Turner, Lyn Turkstra, Roger S McIntyre, Rachel J Couban, Tyler Pitre, Sarah Kirsh, Tanvir Jassal, Michael Ling, Samantha Chakraborty, Signe A Flottorp

“…Our outcomes of interest will include patient-reported fatigue, pain, postexertional malaise, changes in education or employment status, cognitive function, mental health, dyspnoea, quality of life, physical function, recovery and serious adverse events.For each outcome, when possible, we will perform a frequentist random-effects network meta-analysis. …”
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The additional impact of metabolic syndrome on left ventricular deformation and myocardial energetic efficiency impairment in ischemia with nonobstructive coronary arteries patient... by Chen-Yan Min, Yue Gao, Yuan Li, Yi-Ning Jiang, Ying-Kun Guo, Hua-Yan Xu, Rong Xu, Xi Liu, Li-Ting Shen, Zhi-Gang Yang

“…Metabolic syndrome (MetS) is a complex of multiple cardiac metabolic risk factors, significantly increasing the risk of major adverse cardiovascular events in INOCA patients. The study aimed to investigate the aggravating effect of MetS on left ventricular (LV) deformation and function impairment in INOCA patients. …”
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Analyzing the impact of glycemic metabolic status on cardiovascular mortality and all-cause mortality related to the estimated glucose disposal rate: a nationwide cohort study by Shiming He, Shiming He, Shiming He, Chao Wang, Chao Wang, Chao Wang, Xin Huang, Xin Huang, Xin Huang, Guoan Jian, Guoan Jian, Guoan Jian, Zihao Lu, Zihao Lu, Zihao Lu, Kun Jiang, Kun Jiang, Kun Jiang, Guobo Xie, Guotai Sheng, Yang Zou

“…Specifically, high eGDR levels offer stronger protection in individuals with NFG and prediabetes compared to those with diabetes; moreover, eGDR appears to be more suitable for predicting mortality events in the NFG and prediabetic populations.…”
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