Study on the Influence of Regional Transportation on PM2.5 Based on the RAMS-CMAQ Model in Weihai, a Typical Coastal City of Northern China by Wentao Ning, Zhiwen Xing, Min Wei, Mingyan Li, Meigen Zhang, Houfeng Liu

“…However, heavy pollution events still occurred in winter and spring. In this study, the Integrated Source Apportionment Method (ISAM), a source analysis tool coupled with the Regional Atmospheric Modeling System and the Community Multiscale Air Quality modeling system (RAMS–CMAQ), was used to quantify the contribution of regional transport to PM2.5 and its main components in Weihai during February to March in 2018. …”
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Disease-associated genetic variants in the regulatory regions of human genes: mechanisms of action on transcription and genomic resources for dissecting these mechanisms by E. V. Ignatieva, E. A. Matrosova

“…At the same time, attention is concentrated on the transcriptional level of regulation as an initial step in the expression of any gene. A triggering event mediating the effect of a pathogenic genetic variant on the level of gene expression can be, for example, a change in the functional activity of transcription factor binding sites (TFBSs) or DNA methylation change, which, in turn, affects the functional activity of promoters or enhancers. …”
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Spatial identification of regions exposed to multi-hazards at the pan-European level by T.-E. Antofie, T.-E. Antofie, S. Luoni, A. Tilloy, A. Sibilia, S. Salari, G. Eklund, D. Rodomonti, C. Bountzouklis, C. Corbane

“…We further validate our results by comparing them with empirical data on fatalities and disaster events, revealing a relatively high correlation between statistically significant multi-hazard hotspots and fatalities (<span class="inline-formula"><i>r</i>=0.59</span>). …”
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Highly dynamic and sex-specific expression of microRNAs during early ES cell differentiation. by Constance Ciaudo, Nicolas Servant, Valérie Cognat, Alexis Sarazin, Emmanuelle Kieffer, Stéphane Viville, Vincent Colot, Emmanuel Barillot, Edith Heard, Olivier Voinnet

“…A discrete subset of microRNAs (miRNAs) largely dominated the small RNA repertoire, and the dynamics of their accumulation could be readily used to discriminate pluripotency from early differentiation events. Unsupervised partitioning around meloids (PAM) analysis revealed that differentiating ES cell miRNAs can be divided into three expression clusters with highly contrasted accumulation patterns. …”
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A Panpsychist Interpretation of Evolutionary Theory by Ferhat Onur

“…There are processes or events that manifest as physical happenings when observed from the outside and as mental happenings when experienced from the inside. …”
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Orthopedic Frailty Score and adverse outcomes in patients with surgically managed isolated traumatic spinal injury by Yang Cao, Shahin Mohseni, Babak Sarani, Frank Hildebrand, Ahmad Mohammad Ismail, Maximilian Peter Forssten, Parker Chang, Marcelo A F Ribeiro

“…After adjusting for confounding, frailty was associated with a more than doubling in the risk of in-hospital mortality (adjusted incidence rate ratio (IRR) (95% CI): 2.53 (2.04 to 3.12), p&lt;0.001), a 25% higher overall risk of complications (adjusted IRR (95% CI): 1.25 (1.02 to 1.54), p=0.032), a doubling in the risk of FTR (adjusted IRR (95% CI): 2.00 (1.39 to 2.90), p&lt;0.001), and a 10% increase in the risk of intensive care unit admission (adjusted IRR (95% CI): 1.10 (1.04 to 1.15), p=0.004), compared with non-frail patients.Conclusion The findings indicate that the OFS could be an effective method for identifying frail patients with TSIs who are at a disproportionate risk of adverse events.Level of evidence Level III.…”
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Risk factors for mechanical complications in degenerative lumbar scoliosis with concomitant thoracolumbar kyphosis: does the selection of the upper instrumented vertebra matter? by Weipeng Qiu, Zhuoran Sun, Ze Chen, Siyu Zhou, Qiang Qi, Weishi Li

“…During follow-up, MC events were recorded, and patients were categorized into MC and non-MC groups. …”
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Quantifying Spatiotemporal Changes in Supraglacial Debris Cover in Eastern Pamir from 1994 to 2024 Based on the Google Earth Engine by Hehe Liu, Zhen Zhang, Shiyin Liu, Fuming Xie, Jing Ding, Guolong Li, Haoran Su

“…Additionally, the steep supply slope in the study area facilitates the rapid deposition of collapsed debris onto glacier surfaces, with frequent avalanche events accelerating the mobilization of rock fragments.…”
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Perceptions and reflections of embryo donation recipients: a qualitative follow-up study by Seungho Lee, Salomeh Salari, Mona El-Gayar, Joshua Mangels, Rebecca Flyckt, Jody Madeira, Susan Klock, Steven R Lindheim

“…The main themes identified include a desire to use existing embryos efficiently; religious frameworks encouraging maximal embryo use; satisfaction with and enthusiasm for embryo donation; lack of concern regarding child social adjustment and willingness to disclose donor embryo use to others.Conclusion This qualitative study’s findings affirm that participants find conceiving a child through embryo donation highly satisfying and rewarding, experiencing minimal adverse events or regrets. As respondents identified largely as Christian/Catholic, further studies are warranted to assess the perceptions of a more diverse and generalisable population of recipients and children born via embryo donation.…”
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A study on serum potassium and serum magnesium levels in acute myocardial infarction with special emphasis on rhythm disturbance by K.I.S.N. VAISHNAVI, Vignesh C., Mariraj I., N. Krishna Geetha, Gowri Shankar A.

“…Myocardial infarction (MI) is a severe cardiac event associated with plaque formation in arteries, leading to reduced blood flow to the heart. …”
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Psychosocial factors influencing dietary management in patients with type 2 diabetes and healthy adults: an ecological momentary assessment approach by Junichi Saito, Hiroaki Kumano, Hiroaki Kumano

“…Therefore, this study examined dietary management and psychosocial factors using EMA, comparing type 2 diabetes patients with healthy adults.MethodsA total of 20 patients with type 2 diabetes and 16 healthy adults underwent EMA. Relying on event-contingent recordings, this study evaluated the participants’ mood (e.g., anxiety, anger, vigor), appetite (hunger, craving), meal types (e.g., breakfast), location (e.g., eating out), companions (e.g., family), and dietary lapses (e.g., I ate a larger portion of a meal or snack than I intended) before and after meals. …”
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Differential Expression of IFN-γ, IL-10, TLR1, and TLR2 and Their Potential Effects on Downgrading Leprosy Reaction and Erythema Nodosum Leprosum by Douglas Eulálio Antunes, Isabela Maria Bernardes Goulart, Mayara Ingrid Sousa Lima, Patrícia Terra Alves, Paula Cristina Brígido Tavares, Luiz Ricardo Goulart

“…Leprosy reactions are acute immunological events that occur during the evolution of chronic infectious disease causing neural damage and disabilities. …”
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Optimizing Operating Room Efficiency for Primary Hip and Knee Arthroplasty Using Performance Benchmarks by Koorosh Kashanian, BMSc, Matey Juric, BSc, Tim Ramsay, PhD, Pascal Fallavollita, PhD, Paul E. Beaulé, MD, FAAOS, FRCSC

“…Time points, demographics, and adverse events were recorded. Benchmarks to complete 4 joints in 8 h were: anesthesia preparation time (APT) of <11 min, procedure time of <72 min, anesthesia finish time (AFT) of <21 min, and turnover of <22 min. …”
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Pembrolizumab plus Pemetrexed and Platinum in Metastatic Non-Squamous Non-Small Cell Lung Cancer: A Real-Life Study at a Portuguese Centre by Maria João Santos, Filipa Ferro, Andrea Machado, Ana Sofia Vilariça, Direndra Hasmucrai, Paula Alves

“…The disease control rate was 69.7%. Adverse events occurred in 92.4%, 43.9% had grade 3 - 4 adverse effects. …”
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Evaluation of efficacy and safety of coenzyme Q10 in pediatric hemodialysis patients: a randomized controlled trial by Salma A. Rahman Sharaf, Sarah Farid Fahmy, Heba M. Adel Abou Zaghla, Ahmed Hussein Hassan, Sara Mahmoud Zaki

“…Further research is needed to determine whether coenzyme Q10 treatment improves clinical outcomes such as infection, hospitalization, cardiovascular events, and mortality in pediatric hemodialysis patients. …”
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Blast‐Overpressure Induced Modulation of PARP‐SIRT‐NRF2 Axis in Stress Signaling of Astrocytes and Microglia by Vijaya Prakash Krishnan Muthaiah, Kathiravan Kaliyappan, Ramkumar Thiayagarajan, Supriya Mahajan, Krishnamoorthy Gunasekaran

“…Animal studies indicate the over‐activation of PARP1 as a significant downstream event underlying the neurological sequelae of several traumatic and neurodegenerative disorders, irrespective of the mode of cell death. …”
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tPA‐GFP is a reliable probe for detecting compound exocytosis in human pancreatic β‐cells by Aishwarya A. Makam, Shruti Sharma, Prajwal Nagle, Nandhini M. Sundaram, Vidya Mangala Prasad, Nikhil R. Gandasi

“…Here, we used two cargo proteins (NPY and tPA) labeled with different fluorescent proteins (mCherry GFP and eGFP) and employed total internal reflection fluorescence microscopy (TIRF‐M) to capture distinct single‐granule and multi‐granular fusion events. We identified tPA‐GFP as a better probe for studying compound exocytosis, as it can detect both simple and sequential exocytosis reliably. …”
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Acute Kidney Injury, Mild Cognitive Impairment, and Dementia: A Cohort Study of Patients from SPRINT by Kristen L. Nowak, Anna Ostrow, Ester S. Oh, Zhiying You, Michel Chonchol

“…The incidence rate of MCI, probable dementia, and their composite was higher in participants who experienced an AKI event (n = 270). In the fully adjusted model, AKI was positively associated with probable dementia (hazard ratio, 1.72; 95% CI, 1.07-2.75) and the composite outcome (1.43 [1.01-2.04]). …”
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THE ESSENCE AND COMPONENTS OF THREATS TO THE ECONOMIC SECURITY OF HIGHER EDUCATION INSTITUTIONS by Victoria M. Varenyk, Iryna M. Miro, Zoia S. Pestovska

“…It is proven that risk is the probability of the negative impact of certain events, threat is a set of specific factors that can negatively affect activities, and danger is a specific, identified condition which, if ignored, can lead to significant losses. …”
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Physician characteristics associated with the referral from general practitioners to dental surgeons and proposal for a referral letter template endorsed by dental surgeons in Fran... by Matthias Lamauviniere, Jan Chrusciel, Cassandre Finot, Adrien Basset, Maximillien Graftieaux, Aline Ohl-Hurtaud, Stéphane Sanchez

“…Dental surgeons agreed that GP correspondence could decrease the occurrence of adverse events linked with dental care (mean score: 7.36 ± 2.4, for a maximum of 10). …”
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