Oxygenation and function of endocrine bioartificial pancreatic tissue constructs under flow for preclinical optimization by Brenden N Moeun, Florent Lemaire, Alexandra M Smink, Hamid Ebrahimi Orimi, Richard L Leask, Paul de Vos, Corinne A Hoesli

“…These results were achieved through intraportal infusion which leads to early graft losses and limits the capacity to contain and retrieve implanted cells in case of adverse events. Extra-hepatic sites and encapsulation devices have been developed to address these challenges and potentially create an immunoprotective or immune-privileged environment. …”
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RNAseq of peripheral blood mononucleated cells exposed to platelet-rich fibrin and enamel matrix derivatives by Layla Panahipour, Zahra Kargarpour, Michael Mildner, Hannes Kühtreiber, Reinhard Gruber

“…Abstract Platelet-rich fibrin (PRF) and Enamel Matrix Derivatives (EMD) can support the local regenerative events in periodontal defects. There is reason to suggest that PRF and EMD exert part of their activity by targeting the blood-derived cells accumulating in the early wound healing blastema. …”
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Ultra-processed food intake, genetic polymorphisms, and the risk of dyslipidemia in the adult Korean population by Minsu Cho, Heejin Lee, Jung Eun Lee

“…Participants: 20,044 Korean adults aged ≥40 years in the Health Examinees (HEXA) study, the Cardiovascular Disease Association Study (CAVAS), and the Korea Association Resource (KARE) study Results: During median follow-ups of 4.09, 8.67, and 15.67 years in the HEXA, CAVAS, and KARE studies, respectively, there were a total of 7,331, 786, and 1,732 incident dyslipidemia events. Ultra-processed food intake was not significantly associated with dyslipidemia risk. …”
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Soluble ST2 does not change cardiovascular risk prediction compared to cardiac troponin T in kidney transplant candidates. by Mira T Keddis, Ziad El-Zoghby, Bruce Kaplan, Jeffrey W Meeusen, Leslie J Donato, Fernando G Cosio, D Eric Steidley

“…<h4>Background</h4>Solubility of Tumorigenicity 2 (sST2) is a novel biomarker that better stratifies risk of cardiovascular events (CVE) compared to cardiac troponin T(cTnT) in heart failure. …”
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Historical biogeography and systematics of yellow-bellied toads (Bombina variegata), with the description of a new subspecies from the Balkans by Christophe Dufresnes, Simeon Lukanov, Sven Gippner, Johanna Ambu, Ilias Strachinis, Dragan Arsovski, Benjamin Monod-Broca, Hugo Cayuela, Petros Lymberakis, Daniele Canestrelli, Dan Cogălniceanu, Nikolay A. Poyarkov, Spartak N. Litvinchuk, Tomasz Suchan, Mathieu Denoël, Daniel Jablonski

“…Spatiotemporal patterns of diversification suggest a role for a Late Miocene marine incursion in the Pannonian Plain (Paratethys) as the initial trigger of divergence, followed by a vicariance event in the Apennines and a “sky island” process of Pleistocene differentiation in the Balkan Peninsula. …”
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Thematic Curriculum and Academic Performance of Pupils in Upper Primary Classes: A Case of Selected Primary Schools in Kamwezi Sub-County Rukiga District. by Natukunda, Millia

“…I can also take advantage of teachable moments/spontaneous events to engage them in their learning and promote learners. …”
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Impact of Digital Divide on The Growth and Development of Small and Medium Enterprises in Kabale District: A Case Study of Kigezi Private Sector Promotion Centre Limited. by Kembabazi, Evaline

“…A cross-sectional survey design was adopted to take a snapshot of events as they exist there and then. The focus was on staff and clients of the Kigezi Private Sector. …”
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Investigating the Factors Affecting the Growth of Tourism in Kabale Municipality. by Amiidu, Muriisa

“…Based on results from the study, 100% of the respondents agreed that potential factors that have led to the growth in the Kabale district include; environment and events, community perception, accessibility of infrastructure, good reception, lodge owners and managers, natural attraction, perceived safety and security and Perceived safety and security. …”
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The Climate Change Impact on Agriculture Productivity in Karama Sector, Nyagatare District, Rwanda. by Odile, Twagiramariya

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Efficacy and safety of perioperative sintilimab plus platinum-based chemotherapy for potentially resectable stage IIIB non-small cell lung cancer (periSCOPE): an open-label, single... by Xiangyang Yu, Chujian Huang, Longde Du, Chunguang Wang, Yikun Yang, Xin Yu, Shengcheng Lin, Chenglin Yang, Hongbo Zhao, Songhua Cai, Zhe Wang, Lixu Wang, Xiaotong Guo, Baihua Zhang, Zhentao Yu, Jie He, Kai Ma

“…The key secondary endpoints included the objective response rate (ORR), radical resection (R0) rate, pathological complete response (pCR) rate, event-free survival (EFS), disease-free survival (DFS), OS, treatment-related adverse events (TRAEs), surgical complications, and surgery delay rate. …”
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Enhanced recovery in type A aortic dissection evaluating the efficacy and feasibility of early myocardial reperfusion by Tianyu Niu, Tianyu Niu, Zhishuo Liu, Yu Liu, Zhonglu Yang, Yuguang Ge, Lu Wang, Lin Xia, Hui Jiang

“…There was no significant difference in hospital costs, first-hour chest tube drainage, left ventricular ejection fraction, or postoperative adverse events between the groups, except for the rate of CRRT treatment, where the EMR group had significantly fewer patients requiring postoperative CRRT (10.6% vs. 23.5%, P &lt; 0.05).ConclusionThis study demonstrates that early myocardial reperfusion is a feasible and effective technique for TAAD, offering considerable advantages in reducing ventilation time, ICU stay, hospitalization duration and postoperative renal insufficiency.…”
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Effects of social determinants on children’s health in informal settlements in Bangladesh and Kenya through an intersectionality lens: a study protocol by Helen Elsey, Alastair H Leyland, Linsay Gray, Laura Dean, Bachera Aktar, Zahidul Quayyum, Penelope Phillips-Howard, Ivy Chumo, Caroline Kabaria, Blessing Mberu, Samuel Saidu, Lana Whittaker, Lakshmi K Josyula, Md Imran Hossain Mithu, Ross Forsyth, Eliud Kibuchi, Varun Sai, Sureka Garimella, Proloy Barua, Noemia Teixeira de Siqueira Filha, Tasmiah Selim, Ibrahim Gandi

“…The primary outcomes will be whether a child had diarrhoea, cough, fever and acute respiratory infection (ARI) 2 weeks preceding surveys.Ethics and dissemination The results will be disseminated in international peer-reviewed journals and presented in events organised by the Accountability and Responsiveness in Informal Settlements for Equity consortium and international conferences. …”
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Investigating the Electron-capture Supernova Candidate AT 2019abn with JWST Spectroscopy by Sam Rose, Ryan M. Lau, Jacob E. Jencson, Mansi M. Kasliwal, Kishalay De, Michael E. Ressler, Ori D. Fox, Matthew J. Hankins

“…In part because they are so obscured by dust, it is unknown what produces an ILRT, with hypotheses including high-mass stellar merger events, nonterminal stellar outbursts, and terminal supernova explosions through electron capture in super-AGB (SAGB) stars. …”
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Spatial and temporal variability in sea surface temperatures and monsoon dynamics in the northwestern Arabian Sea during the last 43&thinsp;kyr by J. Maier, J. Maier, N. Burdanowitz, N. Burdanowitz, G. Schmiedl, G. Schmiedl, B. Gaye, B. Gaye

“…SSTs were lowest during Heinrich event 4 (H4) and were comparatively low during H3, H2, the Younger Dryas, and the early and late Holocene. …”
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Successful Pregnancy Outcome in a Patient Treated with Pembrolizumab and Exposed to Fluoro-Deoxyglucose (¹⁸F-FDG) PET/CT: Case Report and Review of Literature by Anna Lucia Mastricci, Felice Sorrentino, Elisa Giansiracusa, Erika Zanzarelli, Graziana Silvana De Lucia, Vincenza Fernanda Fesce, Luigi Nappi, Lorenzo Vasciaveo

“…However, ICIs can impair immune tolerance, potentially increasing immune-related adverse events. The PD-1/PD-L1 pathway, targeted by pembrolizumab, plays a critical role in maternal–fetal immune adaptation, raising concerns about its safety during pregnancy. …”
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Efficacy of dexamethasone or clonidine as adjuvants in interscalene brachial plexus block for preventing rebound pain after shoulder surgery: a randomized clinical trial by Layana Vieira Nobre, Leonardo Henrique Cunha Ferraro, Juscelino Afonso de Oliveira Júnior, Vitória Luiza Locatelli Winkeler, Luis Flávio França Vinhosa Muniz, Hiago Parreão Braga, Plínio da Cunha Leal

“…The primary outcome was rebound pain, defined as sudden onset of pain, moderate to severe intensity (VAS ≥7) without improvement with oral medication, followed by VAS pain at rest, required rescue analgesia, the occurrence of adverse events or complications, and satisfaction survey assessments between groups. …”
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Efficacy and Safety of Sacubitril/Valsartan Versus Amlodipine in Japanese Patients With Essential Hypertension: A Randomized, Multicenter, Open‐Label, Noninferiority Study (PARASOL... by Koichi Yamamoto, Daisuke Yarimizu, Ayano Shimanishi, Shunsuke Eguchi, Kazuma Iekushi, Yoichi Takami, Yoichi Nozato, Kazuomi Kario, Hiromi Rakugi

“…There was no significant difference in the incidence of adverse events (AEs). These results suggested that the blood pressure‐lowering effect of sacubitril/valsartan is comparable to that of amlodipine, with no marked differences in tolerability between the two groups. …”
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Medical care and initial health status of French children returnees from jihadist group operation areas: A cross-sectional study from 2017 to 2020 in one referral French hospital by J. Goutines, L.L. Pham, N. Lucidarme, C. Briand, A. Malka, C. Baker, M. Veyret-Morau, A. Mapelli, A. Klein, T. Baubet, L. De Pontual

“…These results emphasize the importance of considering the developmental aspects of these young children who experimented multiple potentially psychic traumatic events.…”
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Machine-learning versus traditional methods for prediction of all-cause mortality after transcatheter aortic valve implantation: a systematic review and meta-analysis by Clara K Chow, Aravinda Thiagalingam, Rohan Jayasinghe, Sarah Zaman, Stephen Bacchi, Justin Chan, Aashray Gupta, Shaun Evans, Pramesh Kovoor, Brandon Stretton, Jayme Bennetts, Ammar Zaka, Naim Mridha, Joshua Kovoor, Gopal Sivagangabalan, Cecil Mustafiz, Daud Mutahar, Shreyans Sinhal, James Gorcilov, Benjamin Muston, Fabio Ramponi, Dale J Murdoch

“…Machine learning (ML) models offer an alternative risk stratification that may offer improved predictive accuracy.Methods PubMed, EMBASE, Web of Science and Cochrane databases were searched until 16 December 2023 for studies comparing ML models with traditional statistical methods for event prediction after TAVI. The primary outcome was comparative discrimination measured by C-statistics with 95% CIs between ML models and traditional methods in estimating the risk of all-cause mortality at 30 days and 1 year.Results Nine studies were included (29 608 patients). …”
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Efficacy of Chinese Herbal Medicine in the Treatment of Moderate-Severe Painful Diabetic Peripheral Neuropathy: A Retrospective Study by Yujiao Zheng, Fan Yang, Lin Han, Xiaowen Gou, Fengmei Lian, Wenke Liu, Linhua Zhao, Bing Pang, Xiyan Zhao, Xiaolin Tong

“…Moreover, 2-hour postprandial blood glucose (2hPG) level decreased from 10.77±1.29 mmol/L at baseline to 9.66±0.60 mmol/L at month 6 (P<0.05). No serious adverse events occurred throughout the treatment period. The modified HGWD was effective in the treatment of moderate and severe pDPN and can thus be offered as a new alternative treatment option for pDPN patients who failed to respond to regular pharmaceutical therapies.…”
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