Understanding personality pathology in a clinical sample of youth: study protocol for the longitudinal research project ‘APOLO’ by Nagila Koster, Igor Lusin, Paul T van der Heijden, Odilia M Laceulle, Marcel A G van Aken

“…The included constructs fit the dimensional model of personality development: maladaptive personality traits (dispositional traits), social relations, stressful life events (characteristic adaptations), a turning point (narrative identity) and functioning (eg, achievement of youth specific milestones). …”
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Dyadic effects of illness perception and maladaptive cognitive-emotional regulation strategies on the fear of cancer recurrence in breast cancer patients and spouses: an actor-part... by Hui Ren, Tianye Yang, Songli Mei, Zhu Zhu, Jianjun Shi, Lingling Tong, Jia Yang, Yabin Sun

“…Abstract Purpose Breast cancer, as a stressful event, profoundly impacts the entire family, especially patients and their spouses. …”
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A colheita da floresta: Uma estratégia de desenvolvimento social e economicamente viável ao desmatamento? by Patricia Andrade de Oliveira

“…The World Conference of Environment and Development (WCED), held in Rio d Janeiro in June of 1992, was a unique international relations event in the and definitely gave the environment its deserved position in the international agenda as a global concern.During the so-called Rio 92, governmental strategies for the development of local social and economically sustainable development were suggested. …”
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Elevated levels of serum alpha-2-macroglobulin associate with diabetes status and incident CVD in type 1 diabetes by Baohai Shao, Janet K. Snell-Bergeon, Ian H. de Boer, W. Sean Davidson, Karin E. Bornfeldt, Jay W. Heinecke

“…We used linear regression to analyze the association between serum protein levels and T1DM status using 47 healthy controls and 134 T1DM patients without CVD and Cox proportional hazards regression to assess their prediction for incident CVD by a case-cohort study using a subcohort of 145 T1DM subjects and a total of 47 CVD events. Of the 28 serum proteins studied, five of them—alpha-2-macroglobulin (A2M), apolipoprotein A-IV, apolipoprotein L1, insulin-like growth factor 2, and phospholipid transfer protein—were significantly associated with T1DM status, with A2M being 1.6-fold higher in T1DM. …”
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Safety and efficacy of omaveloxolone v/s placebo for the treatment of Friedreich's ataxia in patients aged more than 16 years: a systematic review by Ankita Umrao, Monika Pahuja, Nabendu Sekhar Chatterjee

“…Exploratory outcome measures, such as low-contrast letter visual acuity test, exercise test, T25-FW, 9-HPT, health-related quality of life, and biochemical tests, were also assessed along with adverse events in all the studies. Conclusion Although, the quality of the articles demonstrated low bias. …”
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Analysis on Spatio-temporal Change Characteristics of Extreme Precipitation in Hainan Island by ZHANG Shuqi, XIAO Jing

“…The results show that: ① The spatial distribution of extreme precipitation events in Hainan Island is "more in the east and less in the west"; the eastern part has more precipitation and is more prone to rainstorms, and Jianfengling in the western part is also more likely to have short-term heavy rainfall. ② In the past 43 years, the entire island has been tending towards humidification, with short-term precipitation on the 1st and 3rd day increasing in the north and west, and decreasing in the south; consecutive wet days (CWD) increase, consecutive dry days (CDD) decreases, and the trend of rainstorms and heavy rainstorms increases in eastern, northern and western coastal areas. ③ Extreme precipitation indices PRCPTOT, Rx1day, Rx3day, and R99PTOT show an insignificant increase at rates of 45.57, 1.62, 6.08, and 2.80 mm/10a, respectively; among the extreme precipitation day indices, CDD significantly decreases at a rate of 2.07 d/10a, while CWD, R50, and R100 show an insignificant increase at 0.26, 0.22, and 0.02 d/10a, respectively; the extreme precipitation intensity index SDII show an insignificant decrease at 0.18 (mm/d)/10a. ④ In the future, CDD and SDII will continue to increase with strong persistence, and PRCPTOT, Rx1day, Rx3day, R99PTOT, CWD, R50, and R100 will continue to decrease with weak persistence. ⑤ Mutation test shows that mutations in PRCPTOT, Rx1day, Rx3day, R99PTOT, R50, and R100 occurred around 2007, the SDII mutation point appeared in 1988, and the CWD and CDD mutation points appeared around 1995 and 2010, respectively. …”
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Biology, genetics, and ecology of the cosmopolitan ectomycorrhizal ascomycete Cenococcum geophilum by Huayong Wang, Annegret Kohler, Francis M. Martin, Francis M. Martin

“…Several C. geophilum isolates are known to enhance the drought resistance of host plants, a trait that is becoming increasingly important in the context of climate change and frequent drought events. In this review, we examined genetic studies that have assessed the phylogenetic structure of C. geophilum populations and identified the genes associated with adaptation to environmental stress and symbiosis. …”
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Criminal procedural consequences of the court’s return of an indictment to the prosecutor by O. M. Drozdov, N. V. Glynska, I. V. Basysta

“…It has been concluded that in case of the opposite development of events, due to the commission of a criminal procedural offence by the prosecutor, there will be grounds for criminal procedural consequences, for example, the court's declaring the evidence inadmissible or those provided for in paragraph 10 of Part 1 of Article 284 of the Criminal Procedure Code of Ukraine.…”
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Electrically Controlled Rotor Blade Vortex Interaction Airloads and Noise Analysis Using Viscous Vortex Particle Method by Taoyong Su, Yang Lu, Jinchao Ma, Shujun Guan

“…The results show that since the BVI event of the ECR on the advancing side is mainly caused by the interaction between the flap tip vortex and the blade, the blade spanwise range of ECR BVI occurrence on the advancing side is smaller than that of the conventional rotor. …”
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The antihypertensive efficacy of a quadruple single-pill combination in patients with resistant hypertension: study protocol for a randomized, open-label, crossover trial by Yuanyuan Yao, Xin Zhang, Runyu Ye, Shanshan Jia, Xiangyu Yang, Xiaoping Chen

“…Compelling evidence has shown that such a population has a greater risk of cardiovascular events as well as mortality. Although mineralocorticoid receptor antagonists (MRAs) have been shown to be an effective fourth-line treatment for RH, a significant proportion of RH patients do not achieve their blood pressure target. …”
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Association between right atrial area measured by echocardiography and prognosis among pulmonary arterial hypertension: a systematic review and meta-analysis by Ke Liu, Chunhua Zhang, Bingyu Chen, Mingfeng Li, Peican Zhang

“…Objective The purpose of this meta-analysis was to evaluate the association between enlarged right atrial area (RAA), as measured by echocardiography, and prognosis of patients with pulmonary arterial hypertension (PAH).Design Systematic review and meta-analysis.Data sources To identify potential publications, a comprehensive literature search through MEDLINE, the Cochrane database and the Embase database was performed up to December 2019.Eligibility criteria for selecting studies Studies were included if they reported Cox regression based-HRs with 95% CIs for all-cause mortality or composite endpoint consisting of death and PAH-related events for echocardiography measurements of the RAA or the right atrial area index (RAAI) in patients with PAH.Data extraction and synthesis The unadjusted HR with 95% CI was extracted for the final pooled analysis. …”
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Milestones and Timescale of Poststroke Recovery: A Cohort Study by Marianna Loi, Alberto Zaliani, Marta Abbamonte, Elena P. Ferrari, Roberto Maestri, Luigi Trojano, Pietro Balbi

“…In this observational monocentric cohort study, 176 poststroke inpatients at their first cerebrovascular event were consecutively enrolled. A novel measure based on the time needed to reach the main milestones of motor recovery was proposed. …”
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Substrate system outperforms water-culture systems for hydroponic strawberry production by George Kerrigan Hutchinson, Lan Xuan Nguyen, Zilfina Rubio Ames, Krishna Nemali, Rhuanito Soranz Ferrarezi

“…In recent years, due to increasing costs of production and occurrence of extreme weather events, the use of controlled environment agriculture (CEA) and hydroponics for strawberry production has become popular in several Asian, European, and American countries. …”
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Allogenic faecal microbiota transplantation for antibiotic-associated diarrhoea in critically ill patients (FEBATRICE)-Study protocol for a multi-centre randomised controlled trial... by Ivana Cibulkova, Veronika Rehorova, Hana Soukupova, Petr Waldauf, Monika Cahova, Jan Manak, Martin Matejovic, Frantisek Duska

“…Secondary outcomes include safety measures such as systemic inflammatory response, adverse events, and also diarrhoea recurrence within 28 days. …”
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Assessment of left ventricle myocardial performance index (Tei index) by myocardial tissue Doppler imaging and its correlation with serum thyroid-stimulating hormone levels and ath... by Amratansh Varshney, Satyajit Singh, Amritava Ghosh, Surendra Kumar Naik, Abhishek Kumar, Chandraprakash Thakur, Muneshwar Kumar, Nupur Goyal, Nabodoy Majumder, Rounak Kumar, Muhammad Rihas Rasheed

“…AIP may serve as an effective screening method to identify subclinical hypothyroid individuals who are at higher risk of cardiovascular events. Large prospective studies are needed to validate the AIP-TSH-MPI relationship.…”
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Central nervous system (CNS) medications and polypharmacy in later life: cross-sectional analysis of the English Longitudinal Study of Ageing (ELSA) by Natasha Slater, Simon White, Martin Frisher

“…For all CNS medicine classes, polypharmacy may need to be considered in relation to reducing the risk of potential adverse events. After adjustment, lower wealth is associated particularly with analgesics, highlighting that socioeconomic factors may play a role in the prescribing of CNS medicines. …”
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Impact of handgrip strength on cardiovascular, cancer and all-cause mortality in the Korean longitudinal study of ageing by Gyu Ri Kim, Jiyu Sun, Minkyung Han, Sohee Park, Chung Mo Nam

“…The cause-specific hazards regression analysis was also used to model cardiovascular and cancer mortality, by treating deaths from the cause of interest as events and other causes of death as censored.Participants 5859 participants aged 50 years or older were followed up until death or until the date of censoring (31 December 2014).Primary outcome measures The study outcomes of interest were all-cause, cardiovascular and cancer mortality.Results Of the participants included in analyses, 515 individuals (8.8%) died, reflecting an overall crude mortality rate of 11.0 deaths per 1000 person-years. …”
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Renal impairment as a risk factor for chemotherapy induced neutropenia in the treatment of trifluridine/thymidine phosphorylase inhibitor plus bevacizumab by Masatsune Shibutani, Hideki Tanda, Hiroaki Kasashima, Tatsunari Fukuoka, Shinichiro Kashiwagi, Kiyoshi Maeda

“…As TPI is excreted by the kidneys, the risk of adverse events is likely to be high in patients with an impaired renal function. …”
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Programmed cell death 1 inhibitor alone or combined with chemotherapy for patients with locally advanced or metastatic urothelial carcinoma: a single-center experience by Xing Huang, Chupeng Sun, Peng Zhang, Lei Wang

“…Treatment-related adverse events (AEs) of any grade occurred in 5 (71.4%) patients who received PD-1 inhibitor and 24 (85.7%) patients who received PD-1 inhibitor plus chemotherapy. …”
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The serum levels of gasdermin D in uremic patients and its relationship with the prognosis: a prospective observational cohort study by XiaPing Zhang, Bo Yang

“…All patients were followed up for 1 year, and patients with major adverse cardiovascular events (MACE) were defined as having a poor prognosis. …”
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