Therapeutic Evidence of Human Mesenchymal Stem Cell Transplantation for Cerebral Palsy: A Meta-Analysis of Randomized Controlled Trials by Baocheng Xie, Minyi Chen, Runkai Hu, Weichao Han, Shaobo Ding

“…In the subgroup analysis, the results showed that hMSC therapy significantly increased GMFM scores of 3, 6, and 12 months and CFA of 3, 6, and 12 months. Adverse event (AE) of upper respiratory infection, diarrhea, and constipation was not statistically significant between the two groups. …”
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The Impact of Baseline Risk Factors on the Incidence of Febrile Neutropenia in Breast Cancer Patients Receiving Chemotherapy with Pegfilgrastim Prophylaxis: A Real-World Data Analy... by Edward Li, Bridgette Kanz Schroader, David Campbell, Kim Campbell, Weijia Wang

“…**Discussion:** The choice of FN definition significantly changed the impact of risk factors on the FN outcomes in our study, demonstrating the importance of evaluating all proxies for true FN events in a database study. This is particularly important during real-world study planning where potential missteps may lead to bias or confounding effects that render a study meaningless. …”
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Analysis of vulnerability, its drivers, and strategies applied towards reducing the pastoral and agro-pastoral livelihood vulnerability to climatic shocks by Daniel Assefa Tofu, Tegegn Dilbato, Chalchisa Fana, Niguse Bekele Dirbaba, Gutu Tesso

“…Abstract In recent decades, the global climate has changed mainly due to human-induced causes and realizing their manifestations in the forms of extreme events such as droughts, floods, heat stress, and variability in rainfall. …”
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Exceeding the limits of paediatric heat stress tolerance: the risk of losing a generation to climate inaction by Sulani Nyimbili, Anna Bershteyn, Alexander Azan, Oyinkansola O Babayode

“…Paediatricians and other child healthcare providers have a crucial role in research, education, clinical practice and advocacy to protect children during extreme heat events. Paediatricians, other child healthcare providers and stakeholders of children’s well-being are urged to act on young children’s behalf and to elevate youth leadership in GHG mitigation and extreme heat adaptation policy-making.…”
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Post-Spring Frost Canopy Recovery, Vine Balance, and Fruit Composition in cv. Barbera Grapevines by Filippo Del Zozzo, Ginevra Canavera, Silvia Pagani, Matteo Gatti, Stefano Poni, Tommaso Frioni

“…In 2021, severe frost events affected a large fraction of European viticulture. …”
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Health impacts and economic costs of residential fires (RESFIRES study): protocol for a population-based cohort study using linked administrative data by Lara A Harvey, Nargess Ghassempour, Mark Whybro, W Kathy Tannous

“…Nine data sources will be linked to provide a comprehensive picture of individual trajectories from fire event to first responder use (fire and ambulance services), emergency department presentations, hospital admissions, burn out-patient clinic use and death. …”
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Comparative efficacy and safety of pulmonary surfactant delivery strategies in neonatal RDS: a network meta-analysis by Shiyue Liu, Yu Wang, Xingwang Zhu, Feifan Chen, Yuan Shi

“…SN and LMA had the lowest incidence of adverse events during administration.SN had the highest likelihood of secondary administration. …”
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Transcriptional Systems Vaccinology Approaches for Vaccine Adjuvant Profiling by Diogo Pellegrina, Heather L. Wilson, George K. Mutwiri, Mohamed Helmy

“…This approach provides a narrow perspective on the complex events involved in how adjuvants modulate antigen-specific immune responses. …”
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Impact of extreme heat on health in Australia: a scoping review by Patrick Amoatey, Zhiwei Xu, Chinonso Christian Odebeatu, Neha Singh, Nicholas J. Osborne, Dung Phung

“…Abstract Climate change has been recognized as a driver of increased heatwave events in the Asia Pacific region, including Australia. …”
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The Role of the Military-Political Elite of Egypt in the Struggle for National Independence in the Post-World War II Period (1945-1952) by I. E. Ibragimov

“…During the second quarter of the 20 th century the Egyptian society experienced fairly turbulent and eventful political process that influenced the further development of the country. …”
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Epidemiology and management of atopic dermatitis in England: an observational cohort study protocol by Simon de Lusignan, Carsten Flohr, John Dennis, Helen Alexander, Conor Broderick, Andrew McGovern, Claire Feeney

“…In people first diagnosed with AD during the study period, we will describe differences in treatment escalation by sociodemographic factors using time-to-event analysis.Ethics and dissemination The Health Research Authority decision tool classed this a study of ‘usual practice’, ethics approval was not required. …”
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Evaluation of the effectiveness of a peptide-cytokine agent in the complex therapy of recurrent candidal vulvovaginitis by Elena A. Rosyuk

“…None of the patients in the study groups discontinued therapy due to adverse events, and all patients reported good or excellent tolerability. …”
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Information needs for cancer screening and associated factors of information-seeking behaviour: a qualitative systematic review by Mingyao Zhou, Yuqing Wu, Dan Wang, Fang Cheng

“…The results of the analysis of cancer screening-related information needs content, cancer-specific information needs content, requirements and preferences for information, and associated factors of information-seeking behaviour were reported. Based on the event timeline, we summarised the information needs of the screening demand side into four themes. …”
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Bromhexine Hydrochloride Prophylaxis of COVID-19 for Medical Personnel: A Randomized Open-Label Study by Evgeny N. Mikhaylov, Tamara A. Lyubimtseva, Aleksandr D. Vakhrushev, Dmitry Stepanov, Dmitry S. Lebedev, Elena Yu. Vasilieva, Alexandra O. Konradi, Evgeny V. Shlyakhto

“…Secondary endpoints included time from the first contact with a person with COVID-19 to the appearance of respiratory infection symptoms; the number of days before a first positive SARS-CoV-2 test; the number of asymptomatic participants with a positive nasopharyngeal swab test; the number of symptomatic COVID-19 cases; and adverse events. Results. The rate of the combined primary endpoint did not differ significantly between the active treatment group (2/25 [8%]) and control group (7/25 [28%]); P=0.07. …”
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Biomarkers of residual risk and all-cause mortality after acute coronary syndrome. by Anna Toso, Mario Leoncini, Mauro Maioli, Simona Villani, Francesco Bellandi

“…Background: Adverse cardiovascular events often recur after acute coronary syndrome (ACS), despite secondary prevention measures. …”
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Preserved ratio impaired spirometry, airflow obstruction, and their trajectories in relationship to chronic kidney disease: a prospective cohort study by Ikramulhaq Patel, JingYan Zhang, YinHe Chai, YuShun Qiao, HongJian Gong, Hui Xu, JianBo Zhou

“…This study aimed to investigate the impact of baseline and trajectories of spirometry findings on future chronic kidney disease (CKD) events. This UK Biobank cohort study included participants with CKD who underwent spirometry at baseline (2006–2010). …”
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Immunological Remission as a Basis for Dose Reduction of Immunosuppressors in Autoimmune Hepatitis: Results of Monocenter Surveillance Study by A. O. Bueverov, S. V. Koblov, P. O. Bogomolov

“…This will reduce the risk of adverse events and increase adherence to the therapy. We propose introducing the term “immunological remission” into the clinical lexicon, which, along with biochemical and histological remission, acts as a predictor of persistent remission of AIH.…”
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Climate change risk trap: low-carbon spatial restructuring and disaster risk in petroleum-based economies by Viktor Rözer, Sara Mehryar, Mohammad M M Alsahli

“…The economic risks from climate change can be separated into two categories: physical risks from increased frequency and magnitude of extreme weather and climate events, and transition risks due to rapid decarbonisation leading to stranded assets and shifts in production and the labour market. …”
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Results of the ORION open comparative randomized trial: evaluation of efficacy of the Russian drugs Altevir and Phosphogliv in combined treatment of chronic hepatitis C by V. T. Ivashkin, M. V. Mayevskaya, P. O. Bogomolov, I. G. Nikitin, A. O. Buyeverov, A. V. Lapshin

“…No difference in adverse events rate of between groups was observed.Conclusions. …”
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3‐D Regional Ionosphere Imaging and SED Reconstruction With a New TEC‐Based Ionospheric Data Assimilation System (TIDAS) by Ercha Aa, Shun‐Rong Zhang, Philip J. Erickson, Wenbin Wang, Anthea J. Coster, William Rideout

“…Using TIDAS, we found that the 3‐D SED plume manifests as a ridge‐like high‐density channel that predominantly occurred between 300 and 500 km during 19:00–21:00 UT for this event, with the F2 region peak height being raised by 40–60 km and peak density enhancement of 30%–50%.…”
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