Cytisine compared to combination nicotine replacement therapy to reduce cigarette consumption in relapsed smokers: protocol for a pilot randomized controlled trial by Hassan Mir, Javad Heshmati, Kerri-Anne Mullen, Ashley Baldwin, Evyanne Quirouette, Andrew Pipe, Robert Reid

“…Secondary outcomes include smoking cessation rates and adverse events. A total of 60 participants will be recruited using stratified randomization by sex to ensure gender balance. …”
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Effectof Unit Hydrographs and Rainfall Hyetographs on Critical Rainfall Estimates of Flash Flood by Fanzhe Kong, Wei Huang, Zhilin Wang, Xiaomeng Song

“…Warnings for 12 historical flood events were performed. Warning results show that the success rate was 91.67% and that the critical success index (CSI) was 0.91. …”
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Improving 10-year cardiovascular risk prediction in patients with type 2 diabetes with metabolomics by Ruijie Xie, Teresa Seum, Sha Sha, Kira Trares, Bernd Holleczek, Hermann Brenner, Ben Schöttker

“…This study evaluated whether adding metabolomic biomarkers could enhance the 10-year prediction of major adverse cardiovascular events (MACE) in these patients. Methods Data from 10,257 to 1,039 patients with type 2 diabetes from the UK Biobank (UKB) and the German ESTHER cohort, respectively, were used for model derivation, internal and external validation. …”
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Economic Burden of Contraception Management in Spain by Inmaculada Parra Ribes, Juan José Rascón Poza, Ezequiel Pérez Campos, Ignacio Bugella Yudice, Maria Jesús Rodríguez Domingo

“…An increased LARC methods use could avoid UP events, leading to significant cost-savings for the SNHS.…”
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Efficacy and Safety of Emergent Transcatheter Aortic Valve Implantation in Patients with Acute Decompensated Aortic Stenosis: Systematic Review and Meta-Analysis by Ruochen Shao, Junli Li, Tianyi Qu, Xiaoying Fu, Yanbiao Liao, Mao Chen

“…No statistical differences were found in the occurrence rate of vascular complications (RR 1.11, 95% CI [0.90, 1.36]), major vascular complications (RR 1.14, 95% CI [0.52, 2.52]), permanent pacemaker (PPM) placement (RR 1.05, 95% CI [0.99, 1.11]), cerebrovascular events (RR 1.11, 95% CI [0.98, 1.25]), moderate to severe paravalvular leakage (PVL) (RR 1.23, 95% [CI 0.94 to 1.61]), and device success (RR 0.99, 95% CI [0.97, 1.01]). …”
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Reconstruction of bottom water ventilation changes in the West Philippine Sea during the last glacial-interglacial period by Wei-Cheng Hsiung, Yuan-Pin Chang, Horng-Sheng Mii, Ken Ikehara, Toshiya Kanamatsu, Hui-Ling Lin

“…Our findings, including ventilation age records compiled from the Atlantic and Pacific Oceans, reveal opposing deep-water circulation patterns from the last glacial to the interglacial period, including during the Heinrich Event 1 (HE1) and Younger Dryas (YD). This supports the theory of a seesaw-like oscillation in ocean circulation. …”
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Economic Evaluation of a Novel Lung Cancer Diagnostic in a Population of Patients with a Positive Low-Dose Computed Tomography Result by Michael J. Morris, Sheila A. Habib, Maggie L. Do Valle, John E. Schneider

“…The alarming rate of false positives has resulted in unnecessary utilization of medical resources and increased risk of adverse events from invasive procedures. Consequently, there is a critical need for advanced diagnostics after an initial low-dose computed tomography (LDCT) scan. …”
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Clinical Holistic Medicine: the “New Medicine”, the Multiparadigmatic Physician, and the Medical Record by Søren Ventegodt, Mohammed Morad, Joav Merrick

“…The excellent physician will choose the right paradigm(s) for the person, the illness, or the situation, and will use the case record to keep track of all the subjective and objective factors and events involved in the process of healing through time. …”
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KLEBSIELLA PNEUMONIAE NECROTIZING FASCIITIS OF THE LOWER EXTREMITY IN A 7-MONTH-OLD MALE: A CASE REPORT by Marelno Zakanito, Iswinarno Doso Saputro

“…The clinical manifestations of NF start around a week after the initiating event, with induration and edema, followed by 24 to 48 hours later by erythema or purple discoloration and increasing local fever In the next 48 to 72 hours, the skin turns smooth, bright, and serous, or hemorrhagic blisters develop. …”
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Ribosomal profiling as a tool for studying translation in plants: main results, problems and future prospects by D. A. Afonnikov, O. I. Sinitsyna, T. S. Golubeva, N. A. Shmakov, A. V. Kochetov

“…The advantage of this method is that it provides quantitative estimates of ribosome coverage of mRNA and can detect relatively rare translation events. Using this technology, it was possible to identify and classify plant genes by the type of regulation of their expression at the transcription, translation, or both levels. …”
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CORRELATION OF HYPERNATREMIA TO SUCCESS RATE OF SKIN GRAFT IN BURN PATIENTS DR. SOETOMO GENERAL ACADEMIC HOSPITAL BURN CENTER FROM 2014-2018 by Ephora Christina Wulandari, Lynda Hariani, Agus Santoso Budi

“…This high number became a concerned because skin graft was the main procedure to close large burn wound. This event is affected by many problems, one of them is electrolyte imbalance. …”
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A First Application of the Backward Technique in Social Sciences: Exploring Demographic Noise in a Model with Three Personality Types by Roberto Macrelli, Margherita Carletti, Vincenzo Fano

“…In the realm of dynamical systems described by deterministic differential equations used in biomathematical modeling, two types of random events influence the populations involved in the model: the first one is called environmental noise, due to factors external to the system; the second one is called demographic noise, deriving from the inherent randomness of the modeled phenomenon. …”
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Study on the Key Technology of Controlling the Instability of Deep High-Stress Coal and Rock Mass and Relieving the Danger by Zhijing Zhang, Jianghong Zuo, Dongji Lei

“…After hydraulic caverning, the intensity of coal and rock fracture events is greatly reduced. The research results can effectively identify the influence range of hydraulic cavitation, improve the detection accuracy and efficiency of hydraulic cavitation range, effectively predict and warn the hidden danger of mine safety, and provide a reference for the work of similar mines.…”
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Understanding the impact of racism on surgical outcomes in settler nation-states USA and Canada: a protocol for a systematic review and meta-analysis by Mary Brindle, Oluwatomilayo Daodu, Tyara Marchand, Saffa Aziz, Ifeoluwa Adedipe, Mirna Matta

“…To derive literature-based estimates of the outcome gap for racialised surgical patients, we will systematically review and meta-analyse rates of adverse postoperative events associated with common and/or high-risk operations performed in Canada and the USA.Methods and analysis An electronic search of Medline, Embase, Web of Science, Cochrane Central, CINAHL and Scopus will be conducted to identify studies reviewing complication rates of racialised compared with non-racialised patients from inception to December 2023. …”
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EKOS™ Jena Experience: Safety, Feasibility, and Midterm Outcomes of Percutaneous Ultrasound-Assisted Catheter-Directed Thrombolysis in Patients with Intermediate-High-Risk or High-... by Friederike Klein, Sven Möbius-Winkler, Laura Bäz, Rüdiger Pfeifer, Michael Fritzenwanger, Stefan Heymel, Marcus Franz, Pawel Aftanski, P. Christian Schulze, Daniel Kretzschmar

“…There were 6 major bleeding events resulting in transfusion. No stroke, myocardial infarction, right heart decompensation, or recurrent PE occurred. 31 patients (63%) were discharged without any signs of right ventricular stress. …”
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Kaposi's sarcoma-associated herpesvirus (KSHV) gB dictates a low-pH endocytotic entry pathway as revealed by a dual-fluorescent virus system and a rhesus monkey rhadinovirus expres... by Shanchuan Liu, Sarah Schlagowski, Anna K Großkopf, Natalia Khizanishvili, Xiaoliang Yang, Scott W Wong, Elina M Guzmán, Marija Backovic, Stefano Scribano, Arne Cordsmeier, Armin Ensser, Alexander S Hahn

“…Using the ratio of dual-positive KSHV particles to single-positive capsids as an indicator of fusion events we established KSHV fusion kinetics upon infection of different target cells with marked differences in the "time-to-fusion" between cell types. …”
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Aerosol Measurements over India: Comparison of MAX-DOAS Measurements with Ground-based (AERONET) and Satellite-based (MODIS) Data by Prithviraj Mali, Mriganka Sekhar Biswas, Steffen Beirle, Thomas Wagner, Shrivardhan Hulswar, Swaleha Inamdar, Anoop S. Mahajan

“…MAX-DOAS was also effective at observing high aerosol events, which compared well with ground-based samplers. …”
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Popliteal artery aneurysm is a cause that should not be forgotten in acute limb ischemia by Deniz Sarp Beyazpinar, Mehmet Emir Erol

“…The etiology of ALI was identified as thromboembolic events secondary to atherosclerotic peripheral artery disease (APAD) in 92 patients (89.3%), and as PAA in 11 patients (10.7%). …”
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Optimizing Healthcare Expenditure for Spinal Cord Stimulation in Italy: The Value of Battery Longevity Improvement and a Direct-to-Implant Approach by Federica Tito, Gianfranco Sindaco, Simon Eggington, Elisa Tacconi, Francesca Borghetti, Mara Corbo, Gilberto Pari

“…Costs considered were the initial device implantation procedure, device replacements, and serious adverse event (SAE) management. Italian diagnosis-related group (DRG) tariffs were applied for costs, and a 15-year time horizon was used. …”
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Microbiological hazards associated with the use of water in the post‐harvest handling and processing operations of fresh and frozen fruits, vegetables and herbs (ffFVH). Part 3 (Fr... by EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards), Ana Allende, Avelino Alvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Lieve Herman, Liesbeth Jacxsens, Lapo Mughini‐Gras, Maarten Nauta, Jakob Ottoson, Luisa Peixe, Fernando Perez‐Rodriguez, Panagiotis Skandamis, Elisabetta Suffredini, Jen Banach, Bin Zhou, Maria Teresa daSilva Felício, Laura Martino, Winy Messens, Angela Botteon

“…A WMP aims to maintain the fit‐for‐purpose microbiological quality of the process water and consists of (a) identification of microbial hazards and hazardous events linked to process water; (b) establishment of the relationship between microbiological and physico‐chemical parameters; (c) description of preventive measures; (d) description of intervention measures, including their validation, operational monitoring and verification; and (e) record keeping and trend analysis. …”
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