High and low dose radiotherapy combined with ICIs for MSS colorectal cancer patients with liver metastases: a phase I study (HaRyPOT) by Yuxuan Ding, Yong Feng, Yangfan Ye, Jiayi Shen, Chang Guo, Xia He, Liangjun Zhu, Lijun Wang

“…The study results showed that at three dose levels—single doses of 6Gy (n=3), 8Gy (n=3), and 10Gy (n=3)—the most common treatment-related adverse events (TRAEs) were nausea, vomiting, fatigue, and abnormal liver function. …”
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Structure and Expression Analyses of SVA Elements in Relation to Functional Genes by Yun-Jeong Kwon, Yuri Choi, Jungwoo Eo, Yu-Na Noh, Jeong-An Gim, Yi-Deun Jung, Ja-Rang Lee, Heui-Soo Kim

“…LEPR (SVA-C), ALOX5 (SVA-D), PDS5B (SVA-D), and ABCA10 (SVA-F) genes also showed alternative transcripts by SVA exonization events. Dominant expression of HYAL1_SVA appeared in lung tissues, while HYAL1_noSVA showed ubiquitous expression in various human tissues. …”
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Promoter Methylation Precedes Chromosomal Alterations in Colorectal Cancer Development by Sarah Derks, Cindy Postma, Peter T. M. Moerkerk, Sandra M. van den Bosch, Beatriz Carvalho, Mario A. J. A. Hermsen, Walter Giaretti, James G. Herman, Matty P. Weijenberg, Adriaan P. de Bruïne, Gerrit A. Meijer, Manon van Engeland

“…Conclusions: Since promoter methylation was already present in nonprogressed adenomas without chromosomal alterations, we conclude that promoter methylation can be regarded as an early event preceding TP53 mutation and chromosomal abnormalities in colorectal cancer development.…”
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Coping Strategies in Migraine without Aura: A Cross-Sectional Study by Antonio Russo, Gabriella Santangelo, Alessandro Tessitore, Marcello Silvestro, Francesca Trojsi, Antonio De Mase, Federica Garramone, Luigi Trojano, Gioacchino Tedeschi

“…In the context of a causal relationship between stress and migraine, coping strategies are aimed at managing stressful life events and reducing the distressing emotions connected to them. …”
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Knowledge‐Informed Deep Neural Networks for Solar Flare Forecasting by Ming Li, Yanmei Cui, Bingxian Luo, Xianzhi Ao, Siqing Liu, Jingjing Wang, Shuxin Li, Chenxi Du, Xiaojing Sun, Xin Wang

“…In the future, adopting knowledge‐informed deep neural networks will be an effective way to further improve the forecasting performance for other space weather events.…”
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Impact of Physical Activity on Cancer-Specific and Overall Survival of Patients with Colorectal Cancer by Gaetan Des Guetz, Bernard Uzzan, Thierry Bouillet, Patrick Nicolas, Kader Chouahnia, Laurent Zelek, Jean-François Morere

“…When higher PA was associated with improved survival, HRs for detrimental events were set to <1. We used EasyMA software and fixed effect model whenever possible. …”
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Screening of Efficient Antifreeze Agents to Prevent Low-Temperature Stress in Vines by Yali Zhang, Mengyao Han, Langjie Wu, Haoyu Wang, Yanying Liang, Xianhang Wang, Zhumei Xi

“…However, important spring temperature fluctuations and frequent frost events in some production areas severely affect grape growth and yield. …”
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Geographic Distribution of HCV Genotypes and Efficacy of Direct-Acting Antivirals in Chronic HCV-Infected Patients in North and Northeast China: A Real-World Multicenter Study by Wencong Li, Jing Liang, Jihong An, Lingdi Liu, Yihui Hou, Lu Li, Wen Zhao, Luyao Cui, Ningning Xue, Zaid Al-Dhamin, Tao Han, Yuemin Nan, Liaoyun Zhang

“…No severe drug-related adverse event was observed. Conclusions. Genotypes 1b and 2a were dominant subtypes in North and Northeast China. …”
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Frequency and progression of azotemia during acute and chronic treatment of congestive heart failure in cats by Sarah Rogg, Jonathan P. Mochel, Debosmita Kundu, Melissa A. Tropf, Allison K. Masters, Darcy B. Adin, Jessica L. Ward

“…Treatment with an angiotensin converting enzyme inhibitor was associated with fewer lifetime KI events (P = .02). Age in years was the only variable associated with shorter survival (hazard ratio, 1.1; 95% CI, 1.0‐1.1; P = .03). …”
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Application of high-quality nursing for COVID-19 patients in makeshift hospitals (优质护理在方舱医院内新型冠状病毒肺炎患者中的应用) by YAN Haichun (闫海春), MI Yuehua (米跃华), ZHAO Chunhua (赵春华), SUN Hongyan (孙红艳), YOU Xin (尤欣), LI Liyuan (李莉媛), ZHANG Xiaoyun (张潇允), MA Lixin (马立新), ZHANG Kungang (张坤岗), JIA Qiong (贾琼), XIAO Jiale (肖嘉乐), HAN Miaomiao (韩苗苗), LIU Siyu (刘思雨), WANG Kaiyan (万开颜)

“…Results There was no death or nosocomial infection case reported. No serious adverse event was reported throughout the study. Conclusion High-quality nursing plays an important role in relief of negative emotion, prevention of cross-infection and promotion of rehabilitation among COVID-19 patients in makeshift hospitals. …”
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Effect of Cell Growth and Proliferation Factors (EGF/PDGF Signaling Pathway) on the Etiopathogenesis of Intrauterine Growth Restriction by Serhan Can İşcan, Erhan Demirdağ, Melek Yaman, Emin Ümit Bağrıacık, Merih Bayram

“…Conclusion: Variations in gene expression during pregnancy cause changes in placental and fetal development by affecting apoptosis and cellular events at different levels. The genetic causes of IUGR can be revealed by investigating these metabolic pathways. …”
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Did selective kinase inhibitors change the management of patients with radioiodine-refractory thyroid cancer? by Tommaso Porcelli, Cristina Luongo, Anna Cerbone, Carmine Di Luccio, Mariantonia Nacchio, Maria Angela De Stefano, Martin Schlumberger, Domenico Salvatore

“…A RECIST partial response was observed in 28% of patients treated with lenvatinib, in 63% of those treated with DT and in one of the two patients treated with selpercatinib. Grade ≥3 adverse events occurred in 13 (42%) patients treated with lenvatinib and only in 1 (9%) patient treated with DT. …”
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Probabilistic Forecasting of Ground Magnetic Perturbation Spikes at Mid‐Latitude Stations by Michael Coughlan, Amy Keesee, Victor Pinto, Raman Mukundan, José Paulo Marchezi, Jeremiah Johnson, Hyunju Connor, Don Hampton

“…Directly forecasting these fluctuations has proven difficult, but accurately determining the risk of extreme events can allow for the worst of the damage to be prevented. …”
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Beyond buzzwords: fostering interdisciplinary and collaborative global health research in Germany and beyond by Maeve Cook-Deegan, Kerem Böge, Walter Bruchhausen, Mizeck Chagunda, Medha Chaturvedi, Meral Esen, Johanna Hanefeld, Beate Kampmann, Carsten Köhler, Charlotte Köhler, Francis Osei, Clarissa Prazeres da Costa, Eva Rehfuess, Thirumalaisamy P. Velavan, Nora Anton, on behalf of the GLOHRA Steering Committee**

“…Additionally, inclusive training sessions and networking events help to bridge disciplinary boundaries, equipping researchers to envision the broader context of their work. …”
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Characteristics and Sources of Intense Geoelectric Fields in the United States: Comparative Analysis of Multiple Geomagnetic Storms by Xueling Shi, Michael D. Hartinger, Joseph B. H. Baker, Benjamin S. Murphy, Paul A. Bedrosian, Anna Kelbert, Erin Joshua Rigler

“…Moreover, most previous studies examining storm‐time geoelectric fields focused on single events or small geographic regions, making it difficult to determine the typical source(s) of intense geoelectric fields. …”
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Hypoxia signature derived from tumor-associated endothelial cells predict prognosis in gastric cancer by Ruiheng Wang, Ruiheng Wang, Guijun Liu, Guijun Liu, Ke Wang, Zhanglei Pan, Zhanglei Pan, Zhihua Pei, Xijiao Hu, Xijiao Hu

“…BackgroundA hypoxic metabolism environment in the tumors is often associated with poor prognostic events such as tumor progression and treatment resistance. …”
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Study on Test‐Mass Charging for Taiji Gravitational Wave Observatory by Ruilong Han, Minghui Cai, Tao Yang, Liangliang Xu, Qing Xia, Xinyu Jia, Dawei Gao, Mengyao Li, Longlong Zhang, Hongwei Li, Jianwei Han

“…This study aims to model the charging of TMs during Galactic cosmic rays and solar proton events (SPEs) using the Monte Carlo simulation toolkit meanwhile with constructing the sophisticated 3D spacecraft. …”
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The leading “blended” civil medical evacuation operation (MEDEVAC) in unforeseen health emergency. From military use to civil development by Nazzareno Fagoni, Giuseppe Stirparo, Giuseppe Maria Sechi, Andrea Comelli, Gabriele Perotti, Guido Francesco Villa, Alberto Zoli, Marco Botteri

“…Outcome and mortality rates among transferred patients were comparable to those within regional intensive care units. One life-threatening event was reported during transport. The return of patient to Lombardy showed a 100 % survival rate. …”
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Long-term effects of post-earthquake landslides on vegetation ecosystem net carbon by Wen He, Baofeng Di, Shaolin Wu, Jierui Li, Wen Zeng, Yajie Zeng, Ruowei Li, Joseph Kimuli Balikuddembe, Hongkai Chen, Bin Zhang, Gang Chen, Constantine A. Stamatopoulos, Ufuk Yazgan, Isaya Kisekka

“…These findings underscore the need for sustainable post-earthquake land management to maintain carbon balance, offering new insights into how seismic events influence global carbon cycles.…”
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Direct calibration using atmospheric particles and performance evaluation of Particle Size Magnifier (PSM) 2.0 for sub-10&thinsp;nm particle measurements by Y. Liu, Y. Liu, A. Yli-Kujala, F. Schmidt-Ott, S. Holm, L. Ahonen, T. Chan, J. Enroth, J. Vanhanen, R. Cai, T. Petäjä, M. Kulmala, Y. Chen, J. Kangasluoma

“…During new particle formation (NPF) events, comparable total particle concentrations were observed between the Half Mini DMPS and PSM 2.0 based on Hyytiälä atmospheric particle calibration. …”
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