A glimpse into the biogeography, seasonality, and ecological functions of arctic marine Oomycota by Brandon T. Hassett, Marco Thines, Anthony Buaya, Sebastian Ploch, R. Gradinger

“…Oomycota are a group of fungal-like organisms that comprise a major clade of eukaryotic life and are parasites of fish, agricultural crops, and algae. …”
Get full text

Liberties of the genome: insertions of mitochondrial DNA fragments into nuclear genome by M. V. Golubenko, V. P. Puzyrev

“…The transition of detached fragments of mitochondrial DNA into the nucleus and their integration into chromosomal DNA is a special kind of genetic variability that highlights the relation between the two genomes and their interaction in a eukaryotic cell. The human genome contains several hundreds of insertions of mtDNA fragments (NUMTS). …”
Get full text

Genome-wide quantification of polycistronic transcription in Leishmania major by Janne Grünebast, Stephan Lorenzen, Joachim Clos

“…Leishmania, and the whole order Trypanosomatida, are early eukaryotes with highly diverged gene expression and regulation pathways, setting them apart from their mammalian hosts and from most other eukaryotes. …”
Get full text

Expression of a Secretory Protein C1qTNF6, a C1qTNF Family Member, in Hepatocellular Carcinoma by Tamotsu Takeuchi, Yoshihiro Adachi, Tomoko Nagayama

“…Methods: Immunohistochemical staining was performed to evaluate the expression of C1qTNF6 in hepatocellular carcinoma tissue specimens. Various eukaryotic recombinant C1qTNF6 proteins were prepared to ask whether C1qTNF6 could activate Akt pathway in human liver sinusoidal microvascular endothelial cells. …”
Get full text

Role and Function of T Cell-Derived Exosomes and Their Therapeutic Value by Yuanyuan Shao, Xiaofeng Pan, Rong Fu

“…Exosomes are membrane-bound extracellular vesicles that are produced in the endosomal compartment of most eukaryotic cells. Containing proteins, RNA, and DNA, exosomes mediate intercellular communication between different cell types by transferring their contents and thus are involved in numerous physiological and pathological processes. …”
Get full text

CTCF, Cohesin, and Chromatin in Human Cancer by Sang-Hyun Song, Tae-You Kim

“…It is becoming increasingly clear that eukaryotic genomes are subjected to higher-order chromatin organization by the CCCTC-binding factor/cohesin complex. …”
Get full text

Evaluation of reference genes for gene expression analysis in Japanese flounder (Paralichthys olivaceus) under temperature stress by Ping Han, Jianming Chen, Zhennan Sun, Shengjie Ren, Xubo Wang

“…Results In this study, we evaluated the suitability of eight genes including ribosomal protein L6 (rpl6), ribosomal protein L9 (rpl9), delta (4)-desaturase, sphingolipid 1 (degs1), cathepsin L (ctsl), eukaryotic translation elongation factor 1 gamma (eef1g), NSA2 ribosome biogenesis homolog (nsa2), eukaryotic translation initiation factor 3, subunit E, a (eif3ea), glutamine amidotransferase class 1 domain containing 1 (gatd1) analyzed from RNA sequencing (RNA-Seq) data and two genes including β-actin (actb) and 18S rRNA ribosomal RNA (18S RNA) selected from literature to obtain the best internal controls in qRT-PCR analysis of Japanese flounder under temperature stress. …”
Get full text

Dynamic and electrophoretic light scattering measurements on microtubules at low concentrations. by Annitta George, Ernesto Alva, Lorenzo Brancaleon, Marcelo Marucho

“…The accurate characterization of microtubules is essential for understanding their roles in various biological activities in eukaryotic cellular processes. In vitro, experimental data on these systems often need more details and information on sample preparation protocols and experimental techniques. …”
Get full text

REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTION by V. M. Merkulov, T. I. Merkulova

“…Sequence-specific (regulatory) transcription factors selectively regulate the transcription levels of different sets of eukaryotic genes depending on cell type, developmental stage, and external signals. …”
Get full text

Malaria and an Amoebic Abscess in a Returning Traveler from Liberia by Mhd Mustafa Albitar, Nafiza Martini, Sandy Alkhalil, Tamim Alsuliman, Ali Alrstom

“…Malaria is an infectious Anopheles mosquito-borne disease caused by five different eukaryotic protozoa parasites. Amoebiasis is a parasitic infection caused by Entamoeba histolytica. …”
Get full text

Legionella pneumophila — The causative agent of Legionnaires’ disease by Loh Teng-Hern Tan, Wei Yu Tee, Tahir Mehmood Khan, Long Chiau Ming, Vengadesh Letchumanan

“…L. pneumophila is a facultative intracellular pathogen that infects and replicates within eukaryotic host cells such as macrophages and protozoan. …”
Get full text

In Vitro Probiotic Evaluation of Yeasts from Coconut and Raffia Juices by Emenike O. Irokanulo, Queen-Esther M. Yadung, Dolapo E. Orotayo, Charles O. Nwonuma, Oreoluwa S. Alonge

“…In this respect, juice-providing plants may diversify eukaryotic probiotic sources for organism preference. …”
Get full text

Structures and mechanisms of the RNA m⁶A writer by Deng Ting, Ma Jinbiao

“…N⁶-methyladenosine (m⁶A) is the most prevalent epigenetic modification found in eukaryotic mRNAs and plays a crucial role in regulating gene expression by influencing numerous aspects of mRNA metabolism. …”
Get full text

Perrault Syndrome Diagnosis in a Patient Presenting to Her Primary Care Provider with Secondary Amenorrhea by Leah May Roberts, Bruce Carnivale

“…Perrault syndrome is a rare autosomal recessive genetic disorder characterized by sensorineural hearing loss and female gonadic eukaryotic dysgenesis. Here, we report the case of a 20-year-old female that presented to her internal medicine physician after suffering from secondary amenorrhea. …”
Get full text

Messenger RNA in differentiating muscle cells—my experience in François Gros’ lab in the 1970s and 80s by Buckingham, Margaret

“…In the early 1970s, it was the beginning of research in his lab on muscle cell differentiation, as a model eukaryotic system for studying mRNAs and gene regulation. …”
Get full text

Analysis of Nuclear Mitochondrial DNA Segments of Nine Plant Species: Size, Distribution, and Insertion Loci by Young-Joon Ko, Sangsoo Kim

“…Nuclear mitochondrial DNA segment (Numt) insertion describes a well-known phenomenon of mitochondrial DNA transfer into a eukaryotic nuclear genome. However, it has not been well understood, especially in plants. …”
Get full text

Plastin Family of Actin-Bundling Proteins: Its Functions in Leukocytes, Neurons, Intestines, and Cancer by Hiroto Shinomiya

“…Sophisticated regulation of the actin cytoskeleton by a variety of actin-binding proteins is essential for eukaryotic cells to perform their diverse functions. …”
Get full text

IQGAP Family Members in Yeast, Dictyostelium, and Mammalian Cells by Katie B. Shannon

“…IQGAPs are found in eukaryotic cells from yeast to human, and localize to actin-containing structures such as lamellipodia, membrane ruffles, cell-cell adhesions, phagocytic cups, and the actomyosin ring formed during cytokinesis. …”
Get full text

Relationships between genomic dissipation and de novo SNP evolution. by Zackery E Plyler, Christopher W McAtee, Aubrey E Hill, Michael R Crowley, Janice M Tindall, Samuel R Tindall, Disha Joshi, Eric J Sorscher

“…Patterns of single nucleotide polymorphisms (SNPs) in eukaryotic DNA are traditionally attributed to selective pressure, drift, identity descent, or related factors-without accounting for ways in which bias during de novo SNP formation, itself, might contribute. …”
Get full text

A Short Report on the Markov Property of DNA Sequences on 200-bp Genomic Units of Roadmap Genomics ChromHMM Annotations: A Computational Perspective by Hyun-Seok Park

“…The non-coding DNA in eukaryotic genomes encodes a language that programs chromatin accessibility, transcription factor binding, and various other activities. …”
Get full text