Mitochondrial targeting of Candida albicans SPFH proteins and requirement of stomatins for SDS-induced stress tolerance by Hyunjeong Kim, Marienela Y. Heredia, Xiao Chen, Maisha Ahmed, Mohammad Qasim, Tracy L. Callender, Aaron D. Hernday, Jason M. Rauceo

“…Growth assay results did not identify any respiration defects in a panel of stomatin and prohibitin mutant strains, suggesting that SPFH respiratory function has diverged in C. albicans from other model eukaryotes. However, a slp2Δ/Δ/slp3Δ/Δ double mutant strain grew poorly in the presence of 0.08% SDS, accumulated intracellular reactive oxidative species, and displayed aberrant ergosterol distribution in the plasma membrane. …”
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