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DNA metabarcoding of benthic algae and associated eukaryotes from Lake Baikal in the face of rapid environmental changes
Published 2022-03-01“…In general, the DNA-metabarcoding method is recommended for studying the structure of algal communities and eukaryotes associated with them.…”
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Monocyte eukaryotic initiation factor 2 signaling differentiates 17-hydroxy-docosahexaenoic acid levels and pain
Published 2025-02-01“…QIAGEN ingenuity pathway analysis identified the top ranked canonical biological pathway to be eukaryotic initiation factor 2 (EIF2) signaling (lower activation level in the low 17-HDHA-high pain group compared to the high 17-HDHA-low pain group (Z score −3)), followed by EIF4 and P70S6K signaling pathways and mTOR signaling. …”
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Metatranscriptomes-based sequence similarity networks uncover genetic signatures within parasitic freshwater microbial eukaryotes
Published 2025-02-01Subjects: Get full text
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The Legionella pneumophila effector PieF modulates mRNA stability through association with eukaryotic CCR4−NOT
Published 2025-01-01“…ABSTRACT The eukaryotic CCR4−NOT deadenylase complex is a highly conserved regulator of mRNA metabolism that influences the expression of the complete transcriptome, representing a prime target for a generalist bacterial pathogen. …”
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Implications of the Use of Eukaryotic Translation Initiation Factor 5A (eIF5A) for Prognosis and Treatment of Hepatocellular Carcinoma
Published 2012-01-01“…Lack of treatment options and late diagnosis contribute to high mortality rate of HCC. In eukaryotes, translation of messenger RNA (mRNA) to protein is a key process in protein biosynthesis in which initiation of translation involves interaction of different eukaryotic translation initiation factors (eIFs), ribosome subunits and mRNAs. …”
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Distinct ecological processes shape micro-eukaryotic generalists and specialists in a canal-disturbed wetland, Lake Weishan, China
Published 2025-01-01Subjects: “…Micro-eukaryotes…”
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And growth on form? How tissue expansion generates novel shapes, colours and enhance biological functions of Turing colour patterns of Eukaryotes.
Published 2025-01-01“…Evidenced in zebrafishes skin and Mimulus petal, Turing-like mechanisms are probably responsible for many periodic color patterns of Eukaryotes. They are characterized by the mathematical relationships linking their cellular or molecular actors, the periodicity and the geometrical range of the patterns they produce: spots, stripes or mazes. …”
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Development of a stable eukaryotic strain producing fully human monoclonal antibody on the basis of the human antibody against ectromelia virus
Published 2018-01-01“…The aim of this study was the development of an original expression system, using gene targeting to integrate the gene encoding the fullyhuman antibody into the transcriptionally active region of the genome of eukaryotic suspension cells CHOS. To develop a stable strain, the cassette vector plasmid pCDNA5/FRTDHFRCHCL containing the site of homologous recombination and the genes encoding heavy and light chains of the fully human antibody of the IgG1/kappa class was constructed at the first step. …”
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Posttranscriptional Suppression of Lipopolysaccharide-Stimulated Inflammatory Responses by Macrophages in Middle-Aged Mice: A Possible Role for Eukaryotic Initiation Factor 2α
Published 2014-01-01“…Given that a reduced rate of protein synthesis is a common age-related biochemical change, which is partially mediated by increased phosphorylation of eukaryotic initiation factor-2α (eIF-2α), we investigated the mechanism responsible for the deterioration of macrophage inflammatory responses, focusing specifically on the age-related biochemical changes in middle-aged mice. …”
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Applications of Recombinant Dna Technology in Gastrointestinal Medicine and Hepatology: Basic Paradigms of Molecular Cell Biology. Part B: Eukaryotic Gene Transcription and Post-Transcripional Rna Processing
Published 2000-01-01“…The transcription of DNA into RNA is the primary level at which gene expression is controlled in eukaryotic cells. Eukaryotic gene transcription involves several different RNA polymerases that interact with a host of transcription factors to initiate transcription. …”
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Establishment of an indirect ELISA method for detecting bovine coronavirus antibodies based on N protein
Published 2025-02-01Subjects: Get full text
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Fungal and oomycete pathogens and heavy metals: an inglorious couple in the environment
Published 2022-04-01Subjects: Get full text
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RNA splicing: a split consensus reveals two major 5′ splice site classes
Published 2025-01-01“…Separating the human 5′ splice site consensus into its two major constituents can help us understand fundamental features of eukaryote genome architecture and splicing mechanisms and inform treatment design for diseases caused by genetic variation affecting splicing.…”
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Linking Innate and Adaptive Immunity: Human Vγ9Vδ2 T Cells Enhance CD40 Expression and HMGB-1 Secretion
Published 2009-01-01“…The main subset of human peripheral blood γδ T cells responds to nonpeptidic antigens, such as isopentylpyrophosphate (IPP), a metabolite in the mevalonate pathway for both eukaryote and prokaryote cells. IPP-primed γδ T cells significantly augment the inflammatory response mediated by monocytes and αβ T cells to TSST-1, the staphylococcal superantigen that is the major causative agent of toxic shock syndrome. …”
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Re-evaluating evidence for giant genomes in amoebae
Published 2024-12-01“…Fully sequenced amoebozoa genomes range from 14.4 to 52.37 mega basepairs, well within the typical single-celled eukaryote expectation. While the whole genome of the historically relevant Amoeba proteus has not yet been fully sequenced, we provide here a statistical analysis using protein-coding genes from transcriptomic data, suggesting that the genome size is consistent with this range, far smaller than previously claimed. …”
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