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221
RNA N4‐acetylcytidine modification and its role in health and diseases
Published 2025-01-01“…Abstract N4‐acetylcytidine (ac4C) modification is a crucial RNA modification widely present in eukaryotic RNA. Previous studies have demonstrated that ac4C plays a pivotal role in viral infections. …”
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222
The effect of salicylic and jasmonic acids on the activity of <i>SnAGO</i> genes in the fungus <i>Stagonospora nodorum</i> Berk. in <i>in vitro</i> culture and during infection o...
Published 2023-12-01“…RNA interference is a gene silencing mechanism that plays an important role in genetic regulation in a number of eukaryotes. Argonaute (AGO) proteins are central to the complex RNA interference system. …”
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223
Antibacterial Activity of Rationally Designed Antimicrobial Peptides
Published 2020-01-01“…Antimicrobial Peptides (AMPs) are components of the first line of defense for prokaryotes and eukaryotes and have a wide range of activities against Gram-negative and Gram-positive bacteria, fungi, cancer cells, and protozoa, as well as viruses. …”
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224
The fungal microbiota modulate neonatal oxygen-induced lung injury
Published 2025-01-01“…While the microbiota significantly influences neonatal health, the relationship between the intestinal microbiome, particularly micro-eukaryotic members such as fungi and yeast, and lung injury severity in newborns remains unknown. …”
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225
The biogenesis, regulation and functions of transitive siRNA in plants
Published 2024-09-01“…Small RNA (sRNA)-mediated RNA interference (RNAi) is a sequence-specific gene silencing mechanism that modulates gene expression in eukaryotes. As core molecules of RNAi, various sRNAs are encoded in the plant genome or derived from invading RNA molecules, and their biogenesis depends on distinct genetic pathways. …”
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226
The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases
Published 2025-01-01“…Phosphatidic acid phosphatase (PAP) is an evolutionarily conserved eukaryotic enzyme that catalyzes the Mg2+-dependent dephosphorylation of phosphatidic acid to produce diacylglycerol. …”
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227
Induction of Apoptosis Coupled to Endoplasmic Reticulum Stress through Regulation of CHOP and JNK in Bone Marrow Mesenchymal Stem Cells from Patients with Systemic Lupus Erythemato...
Published 2015-01-01“…We also found the activation of downstream target eukaryotic translation initiator factor 2α (eIF 2α) and CCAAT/enhancer-binding protein- (C/EBP-) homologous protein (CHOP) in BM-MSCs from SLE patients. …”
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228
Blood transcriptome resources of chinstrap () and gentoo () penguins from the South Shetland Islands, Antarctica
Published 2019-03-01“…Functional gene annotations through pathway analyses of the Gene Ontology, EuKaryotic Orthologous Groups, and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases were performed for each blood transcriptome, resulting in a similar compositional order between the two transcriptomes. …”
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229
Beclin 1-Mediated Autophagy Is Potentiated by an Interaction with the Neuronal Adaptor FE65
Published 2025-01-01“…Autophagy is a vital cellular pathway in eukaryotic cells, including neurons, where it plays significant roles in neurodevelopment and maintenance. …”
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230
A short ncRNA modulates gene expression and affects stress response and parasite differentiation in Leishmania braziliensis
Published 2025-02-01“…Apart from its medical relevance, this organism has a genetic organization that is unique among eukaryotes. Studies of the mechanisms regulating gene expression in Leishmania led us to investigate noncoding RNAs (ncRNAs) as regulatory elements. …”
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231
Genomics Analysis of Metabolic Pathways of Human Stem Cell-Derived Microglia-Like Cells and the Integrated Cortical Spheroids
Published 2019-01-01“…In addition, the metabolic pathways and the signaling pathways involved in cell proliferation, cell death, PIK3/AKT/mTOR signaling, eukaryotic initiation factor 2 pathway, and Wnt and Notch pathways were analyzed. …”
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232
Autophagy protein Atg7 is essential for maintaining malaria parasite cellular homeostasis and organelle biogenesis
Published 2025-02-01“…Autophagy is a ubiquitous eukaryotic process that permits the recycling of intracellular components. …”
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233
Picobirnaviruses: prevalence, genetic diversity, detection methods
Published 2020-10-01“…Data providing evidence that PBVs belong to eukaryotes and a challenging hypothesis stating that PBVs are bacterial viruses are presented. …”
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234
Changing of expression actinbinding proteins in the kidney under dehydration
Published 2018-04-01“…Actin is related to main structural proteins in eukaryotes. In opposite to muscle alpha-actin, beta-actin is expressing in all types of cells. …”
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235
The finding and researching algorithm for potentially oscillating enzymatic systems
Published 2021-06-01“…Oscillatory processes are responsible for cell cycles in both prokaryotes and eukaryotes, for circadian rhythms, for synchronous coupling of respiration with cardiac contractions, etc. …”
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236
GENOME POLITICS: STRATEGY AND TACTICS
Published 1999-01-01“…This is clearly seen when the comparison between the information content (the gene number) and the life cycle of small genomes (plasmids, viruses, singlecellular prokaryotic organisms) is made: large space is occupied by information on replication enzymes and the sequence of replication origin. In higher eukaryotic multicellular organisms the increased complexity of the genome could be expressed as plus function information: for metabolism, for relations with environment, for nervous system. …”
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237
Metadag: a web tool to generate and analyse metabolic networks
Published 2025-01-01“…MetaDAG was tested using two datasets. In an eukaryotic analysis, it successfully classified organisms from the KEGG database at the kingdom and phylum levels. …”
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238
Uncovering proteome variations and concomitant quality changes of different drying methods Cordyceps sinensis by 4D-DIA structural proteomics
Published 2025-02-01“…Notably, there was a significant overlap between ribosome and ribosome biogenesis in eukaryotes pathways. The process of drying Cordyceps sinensis resulted in a significant upregulation of the expression of proteins linked to various metabolic pathways. …”
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239
The subcompartmented oxphosomic model of the phosphorylating system organization in mitochondria
Published 2021-12-01“…The oxidative phosphorylation (OXPHOS) system of mitochondria supports all the vitally important energyconsuming processes in eukaryotic cells, providing them with energy in the form of ATP. …”
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240
Diversity and occurrence of methylotrophic yeasts used in genetic engineering
Published 2020-04-01“…They are highly productive and allow producing eukaryotic proteins with an acceptable glycosylation level. …”
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