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1741
Imbalance of oral microbiome homeostasis: the relationship between microbiota and the occurrence of dental caries
Published 2025-01-01“…Lays the foundation for further research into the etiology of dental caries.…”
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1742
Caspase-11 Modulates Inflammation and Attenuates Toxoplasma gondii Pathogenesis
Published 2016-01-01“…Toxoplasma gondii is an obligate intracellular parasite that is the etiologic agent responsible for toxoplasmosis. Infection with T. gondii results in activation of nucleotide binding domain and leucine rich repeat containing receptors (NLRs). …”
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1743
Elucidation of the Inhibitory Effect of Phytochemicals with Kir6.2 Wild-Type and Mutant Models Associated in Type-1 Diabetes through Molecular Docking Approach
Published 2014-12-01“…Several target proteins have been identified, and the etiology causing diabetes has been reasonably well studied. …”
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1744
Early Maladaptive Schemas in the Patients with Somatoform Disorders
Published 2014-08-01“…The role of not a specific one but a total of maladaptive schemas in etiology may reflect the unspecific general sources of the tendency to somatoform disorders. …”
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1745
Anatomical alterations: biparietal thinning in antiquity. Review of published cases and a new case
Published 2025-01-01“…This review aims to synthesize existing bioarchaeological literature on biparietal thinning, addressing its historical prevalence, geographical distribution, and potential etiologies. This study integrates data from previous bioarchaeological research supplemented with a new case from skeletal remains excavated at the hypogeal cemetery of Santa Maria Maggiore in Vercelli, Northern Italy. …”
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1746
Sex-Specific Differences in the Pathophysiology of Hypertension
Published 2025-01-01“…Additionally, hypertension secondary to other underlying etiologies also exists. While clinical evidence has clearly shown differences in hypertension development in males and females, relatively little is known about the pathophysiological mechanisms behind these differences. …”
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1747
Fourier Transform Infrared Spectroscopy Analysis as a Tool to Address Aβ Impact on Extracellular Vesicles
Published 2025-01-01“…Alzheimer’s disease is a challenge in modern healthcare due to its complex etiology and increasing prevalence. Despite advances, further understanding of Alzheimer’s disease pathophysiology is needed, particularly the role of Aβ neurotoxic peptide. …”
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1748
Protective Effects of BDNF against C-Reactive Protein-Induced Inflammation in Women
Published 2015-01-01“…Since high sensitivity C-reactive protein (hsCRP) is predictive of cardiovascular events, it is important to examine the relationship between hsCRP and other inflammatory and oxidative stress markers linked to cardiovascular disease (CVD) etiology. Previously, we reported that hsCRP induces the oxidative stress adduct 8-oxo-7,8-dihydro-2′deoxyguanosine (8-oxodG) and that these markers are significantly associated in women. …”
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1749
Towards Personalized Radiotherapy in Pelvic Cancer: Patient-Related Risk Factors for Late Radiation Toxicity
Published 2025-01-01“…Normal tissue reactions vary significantly among patients receiving the same radiation treatment regimen, reflecting the multifactorial etiology of late radiation toxicity. Predicting late radiation toxicity is crucial, as it aids in the initial decision-making process regarding the treatment modalities. …”
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1750
An Overview of Innovative Techniques to Improve Cervical Cancer Screening
Published 2006-01-01“…In this overview we will summarize data on cervical cancer epidemiology and etiology and the current cervical cancer screening approach. …”
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1751
Economics of Acute Kidney Injury in the Critical Care Setting: Kidneys Need More Time and Money!
Published 2025-01-01“…Demographic and clinical data, including AKI etiology, healthcare costs, and insurance coverage, were collected and analyzed.Results: Of the 132 patients, 57.6% developed AKI, with sepsis identified as the leading cause (78%). …”
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1752
Identification of Maltase Glucoamylase as a Biomarker of Acute Kidney Injury in Patients with Cirrhosis
Published 2019-01-01“…Data were extracted from the electronic health record including etiology of liver disease, MELD score, history of decompensation, Child-Turcotte-Pugh score, history of AKI, and medication exposures. …”
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1753
Relationship between personality traits and spontaneous coronary artery dissection risk: evidence from Mendelian randomization
Published 2025-02-01“…Despite the elusive nature of its etiology, empirical evidence indicates a substantial correlation between sociopsychological factors and the disorder. …”
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1754
Diagnostic efficiency of exome-based sequencing in pediatric patients with epilepsy
Published 2025-01-01“…ObjectiveEpilepsy, a prevalent neurological disorder, has multifaceted etiologies. Next-generation sequencing (NGS) has emerged as a robust diagnostic tool for this condition. …”
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1755
Role of Neuron-Specific Enolase in the Diagnosis and Disease Monitoring of Sarcoidosis
Published 2022-01-01“…Sarcoidosis is a systemic granulomatous disease of unknown etiology. The diagnosis of sarcoidosis is based on clinicopathologic findings accompanied by the formation of granulomas in multiple organs, including the lung. …”
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1756
Neutrophils: From Inflammatory Bowel Disease to Colitis-Associated Colorectal Cancer
Published 2025-01-01“…Tianyi Chen,1 Jiachen Liu,2 Ruyi Hang,1 Qian Chen,1 Dong Wang1,3 1Cancer Center, Daping Hospital, Army Medical University, Chongqing, People’s Republic of China; 2Radiology Department, Daping Hospital, Army Medical University, Chongqing, People’s Republic of China; 3Oncology Department of Qianjiang Center Hospital, Chongqing University, Chongqing, People’s Republic of ChinaCorrespondence: Dong Wang, Cancer Center, Daping Hospital, 10 Changjiang Zhi Road, Yuzhong Dist, Chongqing, 400042, People’s Republic of China, Tel +86-23-68757151, Fax +86-23-68894062, Email dongwang64@hotmail.comAbstract: Inflammatory bowel disease (IBD) is a non-specific inflammatory disease of digestive tract, primarily manifesting as ulcerative colitis (UC) and Crohn’s disease (CD). The precise etiology of IBD remains elusive. The interplay of genetic factors, environmental influences, and intestinal microbiota contributes to the establishment of an uncontrolled immune environment within the intestine, which can progressively lead to atypical hyperplasia and ultimately to malignancy over a long period. …”
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1757
Clinical characterization of a novel episodic ataxia in young working Cocker Spaniels
Published 2025-01-01“…The condition is suspected to have a primary (genetic) etiology, although the cause of this manifestation has not yet been identified. …”
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1758
Identification and Validation of Pivotal Genes in Osteoarthritis Combined with WGCNA Analysis
Published 2025-01-01“…Through the integration of protein-protein interaction (PPI) analysis, validation in animal models and ROC curve analysis, four pivotal genes (GADD45B, CLDN5, HILPDA and CDKN1B) were finally identified.Conclusion: In conclusion, these identified key genes could serve as novel targets for predicting and treating OA, offering fresh insights into its etiology and pathogenesis.Keywords: osteoarthritis, bioinformatics analysis, WGCNA, GSE data…”
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1759
Immunohistochemical evaluation of P53 in squamous cell carcinoma of the esophagus
Published 2024-10-01“…Background: Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive forms of cancer, particularly prevalent in regions such as East Asia and parts of Africa. The etiology of ESCC is complex, involving a combination of genetic, environmental, and lifestyle factors. …”
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Transplantation and Pregnancy
Published 2024-04-01“…However, factors that may adversely affect pregnancy include the etiology of the disease requiring transplantation, chronic allograft dysfunction, renal failure, cardiopulmonary diseases, hypertension, diabetes, obesity, and infections such as hepatitis B, hepatitis C, and Cytomegalovirus (CMV). …”
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