CLOVES Syndrome: A Review of Clinical, Genetic, and Therapeutic Aspects by Julianna Podolec, Silvia Ciraolo, Joanna Wojda, Adam Sobiński, Zuzanna Kościuszko, Katarzyna Kurza, Agnieszka Kulczycka-Rowicka, Matylda Czerwonka, Katarzyna Lesiczka-Fedoryj, Anna Walczak

“… Purpose of Research: The research aims to provide an in-depth understanding of CLOVES syndrome, detailing its clinical features, epidemiology, etiology, and diagnostic criteria. It focuses on the role of PIK3CA gene mutations, challenges in diagnosis, and treatment options, including PI3K/AKT/mTOR pathway inhibitors. …”
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Investigating new drugs from marine seaweed metabolites for cervical cancer therapy by molecular dynamic modeling approach by Sk Injamamul Islam, Sheikh Sunzid Ahmed, Sarower Mahfuj, Gunjan Das, Md. Mohaimenul Islam Tareq, Mazen Almehmadi, Mamdouh Allahyani, Naif Alsiwiehri, Partha Biswas, Md. Nazmul Hasan, Foysal Ahammad

“…Abstract The etiology of cervical cancer in women is attributed to the continuous infection of the human papillomavirus (HPV). …”
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Chronic Pain in the Emergency Department: A Pilot Mixed-Methods Cross-Sectional Study Examining Patient Characteristics and Reasons for Presentations by Patricia A. Poulin, Jennifer Nelli, Steven Tremblay, Rebecca Small, Myka B. Caluyong, Jeffrey Freeman, Heather Romanow, Yehudis Stokes, Tia Carpino, Amanda Carson, Yaadwinder Shergill, Ian G. Stiell, Monica Taljaard, Howard Nathan, Catherine E. Smyth

“…Participants had questions about the etiology of their pain, concerns about severe pain-related impairment, and problems with medication renewals or efficacy and sometimes felt invalidated in the ED. …”
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Clinical phenotype and genetic analysis of patients with severe oligoasthenospermia carrying heterozygous SOHLH1 c.346-1G>A mutation by Xiaojun Wen, Zhiming Li, Lizi Cheng, Jianhong Wei, Wenjuan Yu, Xiufeng Lin, Xiufeng Lin, Xiaowu Fang

“…Therefore, in this study, we aimed to elucidate the genetic etiology of two cases of male infertility resulting from SOA and clarify the novel clinical phenotype associated with a heterozygous mutation at the c.346-1G>A site of the SOHLH1 gene.Methods and resultsThrough whole-exome sequencing, we found that patients with SOA carried heterozygous mutations at the c.346-1G>A site. …”
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Acute Renal Replacement Therapy in Children with Diarrhea-Associated Hemolytic Uremic Syndrome: A Single Center 16 Years of Experience by Silviu Grisaru, Melissa A. Morgunov, Susan M. Samuel, Julian P. Midgley, Andrew W. Wade, James B. Tee, Lorraine A. Hamiwka

“…Acute kidney injury (AKI) is becoming more prevalent among hospitalized children, its etiologies are shifting, and new treatment modalities are evolving; however, diarrhea-associated hemolytic uremic syndrome (D+HUS) remains the most common primary disease causing AKI in young children. …”
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Strontium–Alix interaction enhances exosomal miRNA selectively loading in synovial MSCs for temporomandibular joint osteoarthritis treatment by Wenxiu Yuan, Jiaqi Liu, Zhenzhen Zhang, Chengxinyue Ye, Xueman Zhou, Yating Yi, Yange Wu, Yijun Li, Qinlanhui Zhang, Xin Xiong, Hengyi Xiao, Jin Liu, Jun Wang

“…Abstract The ambiguity of etiology makes temporomandibular joint osteoarthritis (TMJOA) “difficult-to-treat”. …”
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Tuberculous pericarditis due to silicon oxide exposure. A case report with an imaging approach by Andrés Felipe Donado-Moré, Jorge Ignacio Arrieta-Castaño, Lina Fernanda Acevedo-Forero, Jorge Alberto Carrillo-Bayona, Alejandro Vega-Molina, Wilmer Orlando Aponte-Barrios, Oscar Andrés Franco-Tavera

“…Case presentation: A 52-year-old man previously exposed to silicon oxide who was referred to the Intensive Care Unit of a quaternary care hospital in the city of Bogotá (Colombia) due to hyperdense pericardial effusion, which was initially considered to have a neoplastic etiology. Imaging studies showed results suggestive of tuberculous pericarditis, prompting a pericardiocentesis, with microbiological and molecular detection studies in pericardial fluid that were negative for Mycobacterium tuberculosis and fungi. …”
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Cytopathologic, Histopathologic, and Immunohistochemical Features of Intrahepatic Clear Cell Bile Duct Adenoma: A Case Report and Review of the Literature by William W. Wu, Mai Gu, Di Lu

“…This is the first report to study the etiology of cell clearing in clear cell bile duct adenoma. …”
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Clinical Features and Genetic Background of the Periodic Fever Syndrome with Aphthous Stomatitis, Pharyngitis, and Adenitis: A Single Center Longitudinal Study of 81 Patients by Daša Perko, Maruša Debeljak, Nataša Toplak, Tadej Avčin

“…PFAPA syndrome is the most common autoinflammatory disorder in childhood with unknown etiology. The aim of our study was clinical evaluation of PFAPA patients from a single tertiary care center and to determine whether variations of AIM2, MEFV, NLRP3, and MVK genes are involved in PFAPA pathogenesis. …”
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Assessment of Herpes Simplex Virus Type 1 and 2 by IHC in Association with CD14 Antigen in Placental Tissues from Women with Miscarriage by Zainab A. Hamid, Solaf J. Ali, Ali Hattem Hussain

“…The considerable proportion of HSV-1, HSV-2, and infections found in the placental tissues from miscarriage women could drag the attention of obstetricians to implicate these viruses as possible targets in the etiology of spontaneous abortion case and there is possible association of CD14 with HSV-1 and HSV-2 in women with abortion. …”
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XRCC1 R194W and R399Q Polymorphisms and Colorectal Cancer Risk in a Northeastern Mexican Population by Juan Pablo Meza-Espinoza, Valeria Peralta-Leal, Jorge Durán-González, Nelly Macías-Gómez, Anabel Bocanegra-Alonso, Evelia Leal-Ugarte

“…These results are consistent with many similar studies, but further research is needed to verify whether the XRCC1 R194W and R399Q polymorphisms play a role in CRC etiology. The functional significance of these polymorphisms is unclear, but some studies suggest that they influence DNA repair capacity and, thus, cancer risk.…”
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Two Portuguese Cochlear Implanted Dizygotic Twins: A Case Report by Joana Rita Chora, Helena Simões-Teixeira, Tiago Daniel Matos, Jorge Humberto Martins, Marisa Alves, Raquel Ferreira, Luís Silva, Carlos Ribeiro, Graça Fialho, Helena Caria

“…Individual’s hearing performance after cochlear implant (CI) is variable and depends on different factors such as etiology of deafness, age at implantation, and social/family hearing environment. …”
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Association Analysis of Polymorphisms with Aspirin-Exacerbated Respiratory Disease in a Korean Population by Jin Sol Lee, Joon Seol Bae, Byung-Lae Park, Hyun Sub Cheong, Jeong-Hyun Kim, Jason Yongha Kim, Suhg Namgoong, Ji-On Kim, Choon-Sik Park, Hyoung Doo Shin

“…Findings from the present study might contribute to the genetic etiology of AERD pathogenesis.…”
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Rare Encounter Behind the Ear: Unveiling Kimura Disease in the Postaural Region by Divya Nayani, Siddhartha Nyathani, Rahul Kumar Pitale Ashok

“… Abstract Introduction: Kimura disease, a rare chronic inflammatory disorder primarily impacting subcutaneous tissue, particularly affects young Asian males, with around 200 reported cases in India. Its etiology, linked to an abnormal allergic reaction, remains uncertain, featuring a characteristic indolent growth pattern. …”
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Spectrum of Chronic Gastritis Based on Morphological Examination of Gastric Biopsies by А. S. Tertychnyy, Т. L. Lapina, D. Р. Nagornaya, N. V. Pachuashvili, А. Р. Kiryukhin, А. А. Fedorenko, Р. V. Pavlov, D. D. Protsenko, V. Т. Ivashkin

“…Pathological examination of biopsies was conducted using the updated Sydney system, determining the histological variant and, when possible, the etiology of gastritis. In some cases, chronic gastritis was assessed using the OLGA/OLGIM system.Results. …”
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Epidemiological Characteristics of Hospitalized Burn Patients—A 10-Year Retrospective Study in a Major Burn Center in Serbia by Marina Stojanović, Milana Marinković, Milana Jurišić, Biljana Miličić, Milan Stojičić, Milan Jovanović, Jelena Jeremić, Nemanja Dimić, Svetlana Srećković, Irina Drača Cetušić, Marko Jović

“…The mean age of the population was 54.65 ± 27.15 years. Regarding etiology, flame was the most common (49.0%). Patient comorbidities were noted on admission in 50.1% of cases. …”
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An evaluation of practices and policies used in genetics clinics across the United States to manage referrals for Ehlers-Danlos and hypermobility syndromes by Lauren Boucher, Berkley Nestler, Daniel Groepper, John Quillin, David Deyle, Colin M.E. Halverson

“…Despite a lack of identifiable molecular etiology for these conditions, referrals to medical geneticists for evaluation are commonplace, and they continue to rise. …”
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Diabetic Polyneuropathy in Type 2 Diabetes Mellitus: Inflammation, Oxidative Stress, and Mitochondrial Function by Luis Miguel Román-Pintos, Geannyne Villegas-Rivera, Adolfo Daniel Rodríguez-Carrizalez, Alejandra Guillermina Miranda-Díaz, Ernesto Germán Cardona-Muñoz

“…Treatment should be directed to improve etiologic factors besides reducing symptoms; several approaches have been evaluated to reduce neuropathic impairments and improve nerve conduction, such as oral antidiabetics, statins, and antioxidants (alpha-lipoic acid, ubiquinone, and flavonoids).…”
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Rapidly progressive glomerulonephritis as an unusual type of renal involvement in sarcoidosis: a case report by K. Graňák, M. Vnučák, P. Kleinová, T. Blichová, A. Kollár, I. Dedinská

“…Abstract Introduction Sarcoidosis is a multisystem inflammatory disease of unknown etiology characterized by the formation of noncaseating epithelioid granulomas. …”
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Intermediate between Idiopathic Hypereosinophilia and Chronic Eosinophilic Leukemia: A Report of Two Hypereosinophilic Cases with Possible Novel Molecular Mutations by Jui Choudhuri, Mohammad Eskandari, Yang Shi, Yanhua Wang

“…Cases of hypereosinophilia without clear reactive etiologies, no evidence of end-organ damage, normal cytogenetics, and no molecular mutations are termed as “Idiopathic Hypereosinophilia (IHE).” …”
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