Recapitulation of Candidate Systemic Lupus Erythematosus-Associated Variants in Koreans by Ki-Sung Kwon, Hye-Young Cho, Yeun-Jun Chung

“…Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organ systems. Although the etiology of SLE remains unclear, it is widely accepted that genetic factors could be involved in its pathogenesis. …”
Get full text

Ambient Air Pollution and Congenital Heart Disease: Updated Evidence and Future Challenges by Francesca Gorini, Alessandro Tonacci

“…Congenital heart disease (CHD) represents the major cause of infant mortality related to congenital anomalies globally. The etiology of CHD is mostly multifactorial, with environmental determinants, including maternal exposure to ambient air pollutants, assumed to contribute to CHD development. …”
Get full text

Molecular Markers in Upper Urothelial Carcinoma Associated to Balkan Endemic Nephropathy. Aristolochic Acid as the Major Risk Factor of the Worldwide Disease by Ljubinka Jankovic Velickovic, Takanori Hattori, Vladisav Stefanovic

“…The role of aristolochic acid in the etiology of Balkan endemic nephropathy (BEN) and associated upper urothelial carcinoma (UUC) was recently confirmed. …”
Get full text

Deep learning-based prediction of autoimmune diseases by Donghong Yang, Xin Peng, Senlin Zheng, Shenglan Peng

“…Abstract Autoimmune Diseases are a complex group of diseases caused by the immune system mistakenly attacking body tissues. Their etiology involves multiple factors such as genetics, environmental factors, and abnormalities in immune cells, making prediction and treatment challenging. …”
Get full text

Simultaneous Presentation of a Right Littre’s Hernia and a Left Amyand’s Hernia in a School-Aged Patient by Andrés Eduardo Velásquez-Bueso, Luis Enrique Sánchez-Sierra, Sergio David Villeda-Rodríguez, Roberto Antonio Martínez-Quiroz

“…Both entities should be considered as a differential diagnosis when it comes to a pediatric patient with unilateral or bilateral inguinal hernias with an uncertain etiology, allowing an early diagnosis and prompt treatment. …”
Get full text

Xeroderma Pigmentosum with Severe Neurological Manifestations/De Sanctis–Cacchione Syndrome and a Novel XPC Mutation by Esteban Uribe-Bojanini, Sara Hernandez-Quiceno, Alicia María Cock-Rada

“…Multigene panel testing is becoming more widely available and accessible in the clinical setting and will help rapidly unveil the molecular etiology of these rare genetic disorders.…”
Get full text

Transient Complete Unilateral Oculomotor Nerve Palsy following Clipping of Ruptured Anterior Communicating Artery Aneurysm: An Abstruse Phenomenon by Joe M. Das, Rashmi Sapkota, Manish Mishra

“…Computed Tomogram and Magnetic Resonance Imaging scans of the brain did not yield any useful information regarding its etiology. She was conservatively managed and kept on regular follow-up. …”
Get full text

Determination of Mealybug Population Density for Transmission of Pineapple Mealybug Wilt Disease in Central Uganda by B. Bua, M. E. Mawa, J. Ayiga, A. Ocwa

“…Yet, closing this knowledge gap would provide a better understanding of PMWD etiology and development of sound management strategies. …”
Get full text

The Alterations in the Brain Corresponding to Low Back Pain: Recent Insights and Advances by Xuyang Li, Fancheng Meng, Wenye Huang, Yue Cui, Fanbo Meng, Shengxi Wu, Hui Xu

“…It will not only further our understanding of etiology of LBP and understanding of negative emotions accompanying with back pain but also provide ideas and basis for new accesses to the diagnosis, treatment, and rehabilitation afterward based on integral medicine.…”
Get full text

Endovascular Management of a Refractory Pseudoaneurysm of the Sternocleidomastoid Artery Caused by Attempted Internal Jugular Central Line Placement with Long-Term Follow-Up: A Cas... by Yassmeen Abdel-Aty, Michael P. Bellew

“…A handful of cases of superior thyroid artery pseudoaneurysms due to several etiologies are reported, but none involving the SBSTA. …”
Get full text

Prevalence of non-alcoholic fatty liver disease at obesity and its interrelation with cardio-vascular disease and 2nd type diabetes mellitus risk factors by G. A. Melnichenko, A. Yu. Yeliseyeva, M. V. Mayevskaya

“…At the investigation past history, anthropometric data, level of blood pressure were analyzed, blood lipid spectrum, activity of ALT, AST, markers of viral hepatites – HbsAg, HCV-at (to rule out viral etiology of liver disease), fasting and at 120-th minute of the standard glucose tolerance test blood glucose and immunoreactive insulin were determined. …”
Get full text

NCK2 Is Significantly Associated with Opiates Addiction in African-Origin Men by Zhifa Liu, Xiaobo Guo, Yuan Jiang, Heping Zhang

“…Substance dependence is a complex environmental and genetic disorder with significant social and medical concerns. Understanding the etiology of substance dependence is imperative to the development of effective treatment and prevention strategies. …”
Get full text

A Possible Novel Anti-Inflammatory Mechanism for the Pharmacological Prolyl Hydroxylase Inhibitor 3,4-Dihydroxybenzoate: Implications for Use as a Therapeutic for Parkinson’s Disea... by Shankar J. Chinta, Subramanian Rajagopalan, Abirami Ganesan, Julie K. Andersen

“…Although the precise etiology of PD is unknown, accumulating evidence suggests that PD involves microglial activation that exerts neurotoxic effects through production of proinflammatory cytokines and increased oxidative and nitrosative stress. …”
Get full text

Hemophagocytic lymphohistiocytosis following enteric fever: A rare autopsy case report by Gwendolyn Fernandes, Pooja Mhashete, Pranav Pramod Patwardhan

“…Investigations for the etiology of fever and blood cultures were negative while the bone marrow aspirate revealed a normocellular marrow. …”
Get full text

Visceral Myopathy Presenting as Acute Appendicitis and Ogilvie Syndrome by Punyaram Kharbuja, Raghvendra Thakur, Jian Suo

“…Visceral myopathy is rare pathological condition of gastrointestinal tract with uncertain clinical presentation and unknown etiology. It often presents with symptoms of chronic intestinal pseudoobstruction of colon. …”
Get full text

Accumulation of Deficits as a Proxy Measure of Aging by Arnold B. Mitnitski, Alexander J. Mogilner, Kenneth Rockwood

“…This pattern reflects an increase in uncompensated deficits in impaired organisms, which would lead to illness of various etiologies, and ultimately to increased mortality. The accumulation of deficits is as an example of a macroscopic variable, i.e., one that reflects general properties of aging at the level of the whole organism rather than any given functional deficiency. …”
Get full text

Lactic Acid Regulation: A Potential Therapeutic Option in Rheumatoid Arthritis by Qianlei Wang, James Asenso, Ning Xiao, Jinzhang Gao, Feng Xiao, Jiajie Kuai, Wei Wei, Chun Wang

“…This seriously affects the quality of work and life of patients. To date, no clear etiology of RA has been found. Recent studies have revealed that the massive proliferation of synoviocytes and immune cells requires a large amount of energy supply. …”
Get full text

Factors Affecting the Occurrence of Out-of-Hospital Sudden Cardiac Arrest by Izabella Uchmanowicz, Wiesław Bartkiewicz, Jarosław Sowizdraniuk, Joanna Rosińczuk

“…The increase in the risk of OHSCA incidence is affected by nervous system diseases (group G), especially epilepsy of various etiologies, respiratory diseases (group J), mainly COPD, and bronchial asthma or mental and behavioral disorders (group F), with particular emphasis on the drugs issue. …”
Get full text

Surgical Removal of a Canine Aortic Thromboembolism Secondary to Pancreatitis by Jill Narak, Emily C. Graff, Katrin Saile, D. Michael Tillson

“…Directed therapy for feline ATE is often not recommended, as underlying conditions are oftentimes ultimately fatal. Underlying etiologies for canine ATE include cardiovascular disease and endocrinopathies, but canine ATE secondary to pancreatitis has not yet been reported. …”
Get full text

Aerobic Exercise Regulates Apoptosis through the PI3K/Akt/GSK-3β Signaling Pathway to Improve Cognitive Impairment in Alzheimer’s Disease Mice by Yan Peng, Rui Chi, Gang Liu, Weijie Tian, Jun Zhang, Rihui Zhang

“…Neuronal apoptosis is an important factor in the etiology of Alzheimer’s disease (AD). Aerobic exercise (AE) enhances learning and memory, improves cognitive impairment, increases telomere binding protein expression, and decreases apoptosis regulators, but it remains unclear whether it can improve cognitive impairment caused by neuronal apoptosis in AD. …”
Get full text