-
1881
Renal Transplantation Dramatically Reduces IgA Anti-beta-2-glycoprotein I Antibodies in Patients with Endstage Renal Disease
Published 2014-01-01“…Patients with different etiologies of ESRD showed higher levels of IgA aB2GPI than blood donors, except the groups of non-IgA glomerular disease and systemic erythematosus lupus, whose nonsignificant differences were observed. …”
Get full text
Article -
1882
Congenital muscular dystrophies and myopathies: the leading cause of genetic muscular disorders in eleven Chinese families
Published 2025-01-01“…In this study, we recruited eleven families with early-onset neuromuscular disorders in China, aimed to clarify the underlying genetic etiology. Methods Essential clinical tests, such as biomedical examination, electromyography and muscle biopsy, were applied to evaluate patient phenotypes. …”
Get full text
Article -
1883
Aqueous humor metabolomic profiling identifies a distinct signature in pseudoexfoliation syndrome
Published 2025-01-01“…PurposePEXS was first described in 1917, yet its etiology still needs clarification. An imbalance between oxidants and antioxidants plays a significant role. …”
Get full text
Article -
1884
NOD-like receptor family pyrin domain containing 3 (rs10754558) gene polymorphism in chronic spontaneous urticaria: A pilot case-control study
Published 2025-01-01“…Objective: This case-control study aimed to determine the association between the NLRP3 inflammasome (rs10754558) single nucleotide polymorphism (SNP) and the occurrence, severity and etiology of CSU. Methods: Each study group included 62 participants; all were subjected to CSU severity evaluation by the urticaria activity score (UAS), autologous serum skin testing (ASST) and NLRP3 (rs10754558) genotyping. …”
Get full text
Article -
1885
Mathematical modeling in autoimmune diseases: from theory to clinical application
Published 2024-03-01“…The research & development (R&D) of novel therapeutic agents for the treatment of autoimmune diseases is challenged by highly complex pathogenesis and multiple etiologies of these conditions. The number of targeted therapies available on the market is limited, whereas the prevalence of autoimmune conditions in the global population continues to rise. …”
Get full text
Article -
1886
Return to play following craniotomy for non-traumatic brain lesions
Published 2025-01-01“…Conclusions: Although limited by sample size, the data provides a foundation to support development of a systematic approach to RTP decision-making following craniotomy for brain lesions of non-traumatic etiology. Future work to develop consensus guidelines will benefit from objective data about outcomes, particularly in relation to repeat imaging prior to RTP.…”
Get full text
Article -
1887
The GWAS-MAP platform for aggregation of results of genome-wide association studies and the GWAS-MAP|homo database of 70 billion genetic associations of human traits
Published 2020-12-01“…The GWAS-MAP platform and database can be used for studying the etiology of human diseases, building predictive risk models and finding potential biomarkers and therapeutic interventions. …”
Get full text
Article -
1888
Cerebrospinal fluid‐specific oligoclonal bands in dogs with idiopathic epilepsy
Published 2025-01-01“…In human medicine, an immune‐mediated etiology is suspected in a subset of ASM‐resistant patients with epilepsy and cerebrospinal fluid (CSF)‐specific immunoglobulin G (IgG)‐type oligoclonal bands (OCBs) have been detected. …”
Get full text
Article -
1889
Colorectal Cancer and Polyps in Diverticulosis Patients: A 10-Year Retrospective Study in 13680 Patients
Published 2019-01-01“…Shared by certain epidemiological and etiological characteristics, diverticulosis and colorectal cancer (CRC) as well as colonic polyps has long been linked. …”
Get full text
Article -
1890
RETRACTED: The Mechanism of Pertussis Cough Revealed by the Mouse-Coughing Model
Published 2022-04-01“…This disease is characterized by severe and uncontrollable coughing, which imposes a significant burden on patients. However, its etiological agent and the mechanism are totally unknown because of a lack of versatile animal models that reproduce the cough. …”
Get full text
Article -
1891
The Relevance of the Virchow Node and Virchow Triad in Renal Cancer Diagnosis
Published 2025-01-01“…<b>Background:</b> The purpose of this article is to overview the clinical significance of left supraclavicular adenopathy and review the etiology of inferior vena cava (IVC) thrombosis, starting from a presentation of a rare case of renal cell carcinoma (RCCs) with Xp11.2 translocation involving TFE3 gene fusion. …”
Get full text
Article -
1892
Microbial dynamics of acute pancreatitis: integrating culture, sequencing, and bile impact on bacterial populations and gaseous metabolites
Published 2025-02-01“…Moreover, NGS verified the presence of the Fusobacteriota phylum and Fusobacteriaceae family only in rectal swabs, which may indicate a link between this type of bacteria and the etiology of diverticulitis. We observed that Escherichia coli 33 isolated from stool exhibited active gaseous metabolite production (mainly hydrogen).ConclusionsThe abundant production of hydrogen may substantially impact enzymatic processes, inducing specific alterations in disulfide bonds and trypsin inactivation. …”
Get full text
Article -
1893
Association of HIVEP3 Gene and Lnc RNA with Femoral Neck Bone Mineral Content and Hip Geometry by Genome-Wide Association Analysis in Chinese People
Published 2020-01-01“…These results provide important information for us to further understand the etiology and genetic pathogenesis of osteoporosis. …”
Get full text
Article -
1894
Peripheral Nerve Blocks Are Associated With Decreased Early Medical Complications, Dislocations, and Opioid Consumption Following Total Hip Arthroplasty
Published 2025-02-01“…Methods: Opioid-naive patients who received PNBs on the same day as undergoing THA for degenerative etiologies were identified from a large national database and matched 1:5 to a control cohort using propensity scoring. …”
Get full text
Article -
1895
Association of vitamin D receptor gene polymorphisms with rheumatoid arthritis
Published 2021-03-01“…Introduction Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease of unknown etiology which causes progressive deterioration of the joints, leading to severe pain and functional disability. …”
Get full text
Article -
1896
Significance of Linked Color Imaging for Predicting the Risk of Clinical Relapse in Ulcerative Colitis
Published 2020-01-01“…Ulcerative colitis (UC) is a chronic inflammatory bowel disease with unknown etiology. Recently, mucosal healing has emerged as an important therapeutic endpoint in UC. …”
Get full text
Article -
1897
Vesicoureteral Reflux in Children with Accidental Diagnosis of Unilateral Small Size Kidney
Published 2024-07-01“…This suggests that VUR may constitute a significant etiological factor in the development of small-size kidneys. …”
Get full text
Article -
1898
Incidence and Risk Factors of Diabetic Foot Ulcer: A Population-Based Diabetic Foot Cohort (ADFC Study)—Two-Year Follow-Up Study
Published 2018-01-01“…These findings provide support for a multifactorial etiology for DFU.…”
Get full text
Article -
1899
Neuroimaging stratification reveals the striatal vulnerability to stress as a risk for schizophrenia
Published 2025-01-01“…The stratified association between the striatum and stress highlights the differential vulnerability to stress, contributing to the complexity of the gene-by-environment etiology of schizophrenia.…”
Get full text
Article -
1900
Modified Trochanteric Flip Osteotomy in Varus Intertrochanteric Osteotomy for Treatment of Legg–Calvé–Perthes Disease
Published 2025-01-01“…<b>Background/Objectives</b>: Legg–Calvé–Perthes disease (LCPD) presents challenges in treatment due to its varied course and unclear etiology. This study aimed to evaluate the efficacy of combining proximal femoral varus osteotomy (PFVO) with a modified trochanteric flip osteotomy to address biomechanical consequences and improve hip abductor muscle strength. …”
Get full text
Article