Long COVID and its risk factors in migrants: a nationwide register study from Sweden by Agneta Cederström, George Frederick Mkoma, Thomas Benfield, Charles Agyemang, Marie Nørredam, Mikael Rostila

“…Abstract Background Many studies have found more severe COVID-19 outcomes in migrants and ethnic minorities throughout the COVID-19 pandemic, while recent evidence also suggests higher risk of longer-term consequences. …”
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Obesity and Gastrointestinal Diseases by Ai Fujimoto, Shu Hoteya, Toshiro Iizuka, Osamu Ogawa, Toshifumi Mitani, Yuichiro Kuroki, Akira Matsui, Masanori Nakamura, Daisuke Kikuchi, Satoshi Yamashita, Tsukasa Furuhata, Akihiro Yamada, Noriko Nishida, Koji Arase, Mitsuyo Hashimoto, Yoshinori Igarashi, Mitsuru Kaise

“…On the other hand, it has been reported that obesity is also associated with Barrett’s esophagus and colorectal adenoma; however, obesity was not a risk factor for these diseases in our study. The difference of ethnicity of our subjects may partly explain why we found no data to implicate obesity as a risk factor for Barrett’s esophagus. …”
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A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment o... by Yan Gong, James Rogers, Christian Friedrich, Sanjay Patel, Alexander Staab, Jorge Luiz Gross, Daniel Polhamus, William Gillespie, Brigitta Ursula Monz, Silke Retlich

“…The final model described HbA1c levels as function of time, dose, baseline HbA1c, washout status/duration and ethnicity. Other covariates showed no major impact on model parameters and were not included. …”
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Aluminium adjuvants versus placebo or no intervention in vaccine randomised clinical trials: a systematic review with meta-analysis and Trial Sequential Analysis by Christian Gluud, Marija Barbateskovic, Sara Russo Krauss, Janus C Jakobsen, Sesilje Bondo Petersen, Sarah Louise Klingenberg, Snezana Djurisic, Mette Kenfelt, De Zhao Kong

“…Objectives To assess the benefits and harms of aluminium adjuvants versus placebo or no intervention in randomised clinical trials in relation to human vaccine development.Design Systematic review with meta-analysis and trial sequential analysis assessing the certainty of evidence with Grading of Recommendations Assessment, Development and Evaluation (GRADE).Data sources We searched CENTRAL, MEDLINE, Embase, LILACS, BIOSIS, Science Citation Index Expanded and Conference Proceedings Citation Index-Science until 29 June 2021, and Chinese databases until September 2021.Eligibility criteria Randomised clinical trials irrespective of type, status and language of publication, with trial participants of any sex, age, ethnicity, diagnosis, comorbidity and country of residence.Data extraction and synthesis Two independent reviewers extracted data and assessed risk of bias with Cochrane’s RoB tool 1. …”
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Genotype Distribution of CNDP1 Polymorphisms in the Healthy Chinese Han Population: Association with HbA1c and Fasting Blood Glucose by Shiqi Zhang, Juan Xu, Di Cui, Shujuan Jiang, Xin Xu, Yi Zhang, Dongchun Zhu, Li Xia, Benito Yard, Yonggui Wu, Qiu Zhang

“…To this end, the (CTG)n allele distribution along with 5 relevant SNPs in the CNDP1 gene, previously reported to be associated with DN in non (CTG)5 carriers of Afro-American ethnicity, were determined in 663 healthy individuals. …”
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The role of the KIBRA and APOE genes in developing spatial abilities in humans by A. V. Kazantseva, R. F. Enikeeva, Yu. D. Davydova, R. N. Mustafin, Z. R. Takhirova, S. B. Malykh, M. M. Lobaskova, T. N. Tikhomirova, E. K. Khusnutdinova

“…Multiple regression analysis, which was carried out in the total sample controlling for sex, ethnicity and the presence of the “risk” APOE ε4 allele, demonstrated the association of the rs17070145 Т-allele in the KIBRA gene with enhanced spatial ability (β = 1.32; pFDR = 0.037) compared to carriers of the rs17070145 CC-genotype. …”
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Cross-sectional design and protocol for Artificial Intelligence Ready and Equitable Atlas for Diabetes Insights (AI-READI) by Gerald McGwin, Linda M Zangwill, Nicholas Evans, Shannon McWeeney, Cecilia S Lee, Bhavesh Patel, Jeffrey C Edberg, Cynthia Owsley, Aaron Lee, Cecilia Lee, Sally L Baxter, Michael Snyder, Samantha Hurst, Nicole Ehrhardt, Christopher Chute, Dawn S Matthies, Julia P Owen, Amir Bahmani, Sally Baxter, Edward Boyko, Aaron Cohen, Jorge Contreras, Garrison Cottrell, Virginia de Sa, Jeffrey Edberg, Irl Hirsch, Michelle Hribar, T.Y. Alvin Liu, Bonnie Maldenado, Sara Singer, Bradley Voytek, Joseph Yracheta, Linda Zangwill

“…The fundamental rationale for promoting health resilience in T2DM stems from its high prevalence of 10.5% of the world’s adult population and its contribution to many adverse health events.Methods AI-READI is a cross-sectional study whose target enrollment is 4000 people aged 40 and older, triple-balanced by self-reported race/ethnicity (Asian, black, Hispanic, white), T2DM (no diabetes, pre-diabetes and lifestyle-controlled diabetes, diabetes treated with oral medications or non-insulin injections and insulin-controlled diabetes) and biological sex (male, female) (Clinicaltrials.org approval number STUDY00016228). …”
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Prevalence of AZFс Y chromosome microdeletions and association with spermatogenesis in Russian men from the general population by L. V. Osadchuk, G. V. Vasiliev, M. K. Ivanov, M. A. Prasolova, M. A. Kleshchev, A. V. Osadchuk

“…The aim of the present study was to assess the frequency of various types of AZFc microdeletions and to search for associations with spermatogenesis parameters in men of Slavic ethnicity from the general Russian population (n = 700, average age 25.8 years). …”
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Physical behaviours during pregnancy may alter the association of maternal insulin sensitivity with neonatal adiposity: a prospective pre-birth cohort of mother-child pairs by Piraveena Satkunanathan, Catherine Allard, Myriam Doyon, Patrice Perron, Luigi Bouchard, Marie-France Hivert, Tricia M. Peters

“…Linear regression analyses assessed the association of insulin sensitivity with birthweight z-score and sum of neonatal skinfold thickness, adjusting for maternal age, race/ethnicity, gravidity, smoking, with and without adjustment for maternal body mass index at V1. …”
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Impact of Flexor Tendon Traction Tenolysis on Clinical Outcomes in Open A1 Pulley Release for Trigger Finger by Shalimar Abdullah, BMBS, MS, Syed Jeffrey Syed Ahmad Kabeer, MBChB, MD, Lim Chia Hua, MD, Jamari Sapuan, MD, MS, Parminder Singh Gill, MBBS, MS, Elaine Soh Zi Fan, MBBS, MD

“…Baseline characteristics, including age, gender (female/male), ethnicity, occupational status, diabetes status, and trigger finger severity, were comparable between the two groups. …”
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Assessment of vitamin D status in obese and non-obese patients: A case-control study by Salma Derbel, Lamiae Zarraa, Imane Assarrar, Nisrine Bouichrat, Siham Rouf, Hanane Latrech

“…Controls (n = 60) were randomly assigned and were matched for age, sex, glycated hemoglobin, ethnicity, and geographic area. The levels of Vitamin D in the serum were determined in obese patients and non-obese controls. …”
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Risk of SARS-CoV-2 infection before and after the Omicron wave in a cohort of healthcare workers in Ontario, Canada by Jorge L. Martinez-Cajas, Ann Jolly, Yanping Gong, Gerald Evans, Santiago Perez-Patrigeon, Bradley Stoner, T. Hugh Guan, Beatriz Alvarado

“…We employed Poisson regression for period #1 and Cox regression for period #2 to examine associations of demographic factors (age, sex, ethnicity, migration status, income insufficiency), health factors (chronic conditions, smoking history, SARS-CoV-2 vaccination status), household factors (exposure to COVID-19), occupational factors (work role, exposure to COVID-19 patients, personal protective equipment access, aerosol-generating procedures) and community exposures (use of masks, distance, hand-washing) with SARS-CoV-2 infection. …”
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Longitudinal associations between air pollution and incident dementia as mediated by MRI-measured brain volumes in the UK Biobank by Rhiannon Thompson, Xinning Tong, Xueyi Shen, Jinjun Ran, Shengzhi Sun, Xiaoxin Iris Yao, Chen Shen

“…Associations between environmental exposures, brain volumes, and dementia cases (diagnosed post-MRI) were tested using linear and logistic regression and adjusted for age, sex, household income, ethnicity, education, smoking, and area-level deprivation. …”
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Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retrospective cohort study by Khalaf Kridin, Khalaf Kridin, Khalaf Kridin, Cristian Papara, Katja Bieber, David A. De Luca, Jan Philipp Klein, Marlene A. Ludwig, Philip Curman, Philip Curman, Philip Curman, Philip Curman, Artem Vorobyev, Astrid Dempfle, Ralf J. Ludwig

“…Using propensity score matching (PSM) to control for age, sex, ethnicity, and other CID risk factors, we contrasted the risk of developing any or any of the 38 CIDs in 881,192 EHRs from individuals with nicotine dependence to PSM-matched unexposed counterparts.ResultsThe analytical pipeline was validated by demonstrating an increased risk of individuals exposed to nicotine dependence for subsequent diagnosis of myocardial infarction, malignant neoplasm of the lung, and chronic obstructive pulmonary disease. …”
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Effect of nirmatrelvir/ritonavir (Paxlovid) on hospitalization among adults with COVID-19: An electronic health record-based target trial emulation from N3C. by Abhishek Bhatia, Alexander J Preiss, Xuya Xiao, M Daniel Brannock, G Caleb Alexander, Robert F Chew, Hannah Davis, Megan Fitzgerald, Elaine Hill, Elizabeth P Kelly, Hemalkumar B Mehta, Charisse Madlock-Brown, Kenneth J Wilkins, Christopher G Chute, Melissa Haendel, Richard Moffitt, Emily R Pfaff, N3C Consortium

“…To emulate randomization, we used the clone-censor-weight technique with inverse probability of censoring weights to balance a set of covariates including sex, age, race and ethnicity, comorbidities, community well-being index (CWBI), prior healthcare utilization, month of COVID-19 index, and site of care provision. …”
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The Relationship between Intramuscular Adipose Tissue, Functional Mobility, and Strength in Postmenopausal Women with and without Type 2 Diabetes by Janet M. Pritchard, Sarah Karampatos, Karen A. Beattie, Lora M. Giangregorio, George Ioannidis, Stephanie A. Atkinson, Lehana Thabane, Hertzel Gerstein, Zubin Punthakee, Jonathan D. Adachi, Alexandra Papaioannou

“…Regression was used to determine associations between the following: (1) type 2 diabetes and IntraMAT (covariates: age, ethnicity, BMI, waist : hip ratio, and energy expenditure), (2) IntraMAT and TUG (covariates: diabetes, age, BMI, and energy expenditure), and (3) IntraMAT and grip strength (covariates: diabetes, age, height, and lean mass). …”
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Painting a portrait: Analysis of national health survey data for cancer genetic counseling by Monica H. Stamp, Ora K. Gordon, Christopher P. Childers, Kimberly K. Childers

“…On bivariate analysis, there were significant differences in proportions undergoing genetic counseling by sex, race/ethnicity, insurance, citizenship, education, age, and cancer status (P < 0.01). …”
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Systematic review and meta‐analysis of the pelvic organ prolapse and vaginal prolapse among the global population by Tharanga Mudalige, Vindya Pathiraja, Gayathri Delanerolle, Heitor Cavalini, Shuqi Wu, Julie Taylor, Om Kurmi, Kathryn Elliot, Sharron Hinchliff, Carol Atkinson, Kristina Potocnik, Paula Briggs, Lucky Saraswat, Helen Felicity Kemp, George Eleje, Toh Teck Hock, Cristina Laguna Benetti‐Pinto, Irfan Muhammad, Rabia Kareem, Yassine Bouchareb, Peter Phiri, Ruishu Zhang, Yunfei Weng, Ieera Aggarwal, Jian Qing Shi, Ashish Shetty, Ian Litchfield, Nirmala Rathnayake, Sohier Elneil

“…The review highlighted a lack of diversity in terms of ethnicity, age and comorbidity status, which are essential to fully understanding the impact of POP. …”
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Personalised Lung Cancer Screening (PLuS) study to assess the importance of coexisting chronic conditions to clinical practice and policy: protocol for a multicentre observational... by Yi Guo, Dongyu Zhang, Rafael Meza, Jihyoun Jeon, Dejana Braithwaite, Gerard A Silvestri, Michael K Gould, Jiang Bian, Bruno Hochhegger, Shama D Karanth, Christopher G Slatore, Martin Tammemagi, Mattthew Schabath, Meghann Wheeler, Frederic J Kaye

“…Data will be integrated into a unified repository to (1) examine the burden of multimorbidity by race/ethnicity, socioeconomic status and age; (2) quantify potential benefits and harms; and (3) use the observational data with validated simulation models in the Cancer Intervention and Surveillance Modeling Network (CISNET) to provide LCS outcomes in the real-world US population. …”
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Early COVID-19 and protection from Omicron in a highly vaccinated population in Ontario, Canada: a matched prospective cohort study by Altynay Shigayeva, Christopher Kandel, Lubna Farooqi, Zoe Zhong, Anne-Claude Gingras, Brenda L. Coleman, Lois Gilbert, Wayne L. Gold, Maria Major, Tony Mazzulli, Samira Mubareka, Jelena Vojicic, Jingyan Yang, Pingping Zhang, Catherine Martin, Moe H. Kyaw, John M. McLaughlin, Allison McGeer

“…Older age, non-White ethnicity, no children in household, and lower neighbourhood income were associated with reduced risk of infection. …”
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