Comparison of Carrying Angle of Elbow between Patients with and without Lateral Epicondylitis: An Observational Study by Sarik Kumar Shrestha, Manoj Kandel, Bhanubhakta Chalise, Keshav Mani Gautam, Sunil Panta, Pritam Chaudhary, Suman Subedi, Prakash Darjee

“…Methods: An observational cross-section study comparing carrying angle of elbow in patient with and without lateral epicondylitis was performed after ethical approval from the Institutional Review Committee (Reference number: 080/081-019) Patients presenting who had undergone radiographic examination of the elbow were recruited in the study and divided into the lateral epicondylitis group and the normal group. …”
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Exploring the role of artificial intelligence in chemotherapy development, cancer diagnosis, and treatment: present achievements and future outlook by Bassam Abdul Rasool Hassan, Ali Haider Mohammed, Souheil Hallit, Souheil Hallit, Souheil Hallit, Diana Malaeb, Hassan Hosseini, Hassan Hosseini

“…Future research should focus on addressing challenges in clinical implementation, ethical considerations, and scalability to enhance AI’s integration into oncology care.…”
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Digital twin-enhanced three-organ microphysiological system for studying drug pharmacokinetics in pregnant women by Katja Graf, José Martin Murrieta-Coxca, Tobias Vogt, Sophie Besser, Daria Geilen, Tim Kaden, Tim Kaden, Anne-Katrin Bothe, Diana Maria Morales-Prieto, Behnam Amiri, Behnam Amiri, Stephan Schaller, Ligaya Kaufmann, Martin Raasch, Ramy M. Ammar, Ramy M. Ammar, Christian Maass, Christian Maass

“…BackgroundPregnant women represent a vulnerable group in pharmaceutical research due to limited knowledge about drug metabolism and safety of commonly used corticosteroids like prednisone due to ethical and practical constraints. Current preclinical models, including animal studies, fail to accurately replicate human pregnancy conditions, resulting in gaps in drug safety and pharmacokinetics predictions. …”
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Determination of the copy numbers of type A porcine endogenous retroviruses in domestic pigs and wild boars by R. B. Aitnazarov, N. S. Yudin, R. S. Kiril’chuk, N. N. Kochnev, S. P. Knyazev, M. I. Voevoda

“…With regard to economic and ethical criteria and to the anatomical and physiological similarity to humans, the pig is the best source of xenografts. …”
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Antifibrotic Effect of Combination of Nilotinib and Stem Cell-Conditioned Media on CCl4-Induced Liver Fibrosis by Gamal Shiha, Ahmed Nabil, Ahmed Lotfy, Reham Soliman, Ayman A. Hassan, Islam S. Ali, Doaa F. Gad, Faten Zahran

“…Stem cell therapy still has some limitations such as oncogenesis, unexpected differentiation, and ethical consideration. Stem cells secrete cytokines and growth factors that showed paracrine-mediated antifibrotic and anti-inflammatory effects in vivo and in vitro. …”
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Pre-pregnancy obesity and weight gain during pregnancy: impact on newborn outcomes by Sezgin Gunes, Suzan Sahin, Meltem Koyuncu Arslan, Nurhan Korkmaz, Ozlem Karaca Dag, Emir Gokalp, Hazal Saban, Mehmet Koca, Mehmet Yekta Oncel

“…The primary outcome was rate of pregestational obesity or overweight as secondary outcomes were weight gain during pregnancy and adherence to guidelines, neonatal outcomes according to different BMI categories and possible impact of maternal weight gain on neonatal morbidities in two different ethic populations. Results Of the 323 mother-infant pairs, overweight/obese mothers had higher birth weights and cesarean-section rates. …”
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Membrana preformativa: Unveiling the unexplored facets of dental development by Sakshi Sikaria, Suganya Panneer Selvam, Ramya Ramadoss, Sandhya Sundar

“…Materials & methods: The procurement of rabbit tooth germ was performed only after obtaining the requisite ethical clearance. Subsequently, the tissues were processed and subjected to Hematoxylin and Eosin staining to facilitate enhanced visualization of the overall tissue architecture and organization & immunohistochemical staining of Ki-67 and Cyclin D1 was performed. …”
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Pharmaceutical orientation and applications of silver/zinc oxide nanoparticles developed from various fruit peel extracts: an emerging sustainable approach by Mahima Chaudhary, Priyvart Choudhary, Anjali Tripathi, Vinay Kumar Pandey, Rohit Sharma, Seema Singh, Sarvesh Rustagi, Amritanshu Pathak

“…Embracing this transformative pathway ensures not only the optimization of nanoparticles for specific applications, but also a more sustainable and ethical trajectory for nanotechnology, contributing to the well-being of both industries and the environment.…”
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The clinical application of artificial intelligence in cancer precision treatment by Jinyu Wang, Ziyi Zeng, Zehua Li, Guangyue Liu, Shunhong Zhang, Chenchen Luo, Saidi Hu, Siran Wan, Linyong Zhao

“…Finally, we outline the current challenges and ethical issues in the field. Conclusions Recent clinical studies demonstrate that artificial intelligence is involved in cancer precision medicine and has the potential to benefit cancer healthcare, particularly by optimizing conventional therapies, emerging targeted therapies, and individual immunotherapies. …”
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Digital twins as global learning health and disease models for preventive and personalized medicine by Xinxiu Li, Joseph Loscalzo, A. K. M. Firoj Mahmud, Dina Mansour Aly, Andrey Rzhetsky, Marinka Zitnik, Mikael Benson

“…However, widespread implementation faces several challenges: (1) characterizing dynamic molecular changes across multiple biological scales; (2) developing computational methods to integrate data into DTs; (3) prioritizing disease mechanisms and therapeutic targets; (4) creating interoperable DT systems that can learn from each other; (5) designing user-friendly interfaces for patients and clinicians; (6) scaling DT technology globally for equitable healthcare access; (7) addressing ethical, regulatory, and financial considerations. …”
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TB drug susceptibility testing in high fluoroquinolone resistance settings by F. Saluzzo, F. Masood, V. Batignani, F. Di Marco, U. Majeed, A. Ghazal, D.M. Cirillo, S. Tahseen

“…METHODS: This cross-sectional prospective study, approved by the local ethical committee, collected samples from people newly and previously diagnosed with TB over 6 months. …”
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Neonatal Screening for Congenital Hypothyroidism: A Study Conducted in a Tertiary Care Hospital of Gujarat by Shubhangi Rathod, Ramesh Pradhan, Rosy Lekharu, Jaydip Vala, Mehak Kulshrestha

“…Materials and methods: In a prospective study approved by the Ethical Committee of GCS Medical College and Hospital, Ahmedabad, 100 neonates (50 males and 50 females) were assessed for thyroid status after excluding those born of known hypothyroid mothers or having a history of distress. …”
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Targeted Inhibition of the miR-199a/214 Cluster by CRISPR Interference Augments the Tumor Tropism of Human Induced Pluripotent Stem Cell-Derived Neural Stem Cells under Hypoxic Con... by Yumei Luo, Xuehu Xu, Xiuli An, Xiaofang Sun, Shu Wang, Detu Zhu

“…The human induced pluripotent stem cell (hiPSC) provides a breakthrough approach that helps overcoming ethical and allergenic challenges posed in application of neural stem cells (NSCs) in targeted cancer gene therapy. …”
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A wicked problem: Systemic issues surrounding Canadian equestrian dressage and dressage horse welfare by Megan Ross, Kathryn Proudfoot, Katrina Merkies, Charlotte Lundgren, Caroline Ritter

“…Competitive dressage’s social licence to operate is in jeopardy due to ethical concerns surrounding the use of horses for dressage. …”
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Comparative Analysis Of Continuous And Interrupted Suturing Techniques In Urethroplasty For Hypospadias by Kamran Aziz, Asra Aleem, Safdar Saeed, Muhammad Rashid Jamal, Ijaz Hussian Shah, Sana Shaukat Siddiqui

“…Methods: A quasi-experimental study was carried out in the Urology department of DG Khan Medical College and Hospital from June 2022 to June 2023 that included 69 boys divided into 2 groups based on suturing technique: 37 boys underwent continuous-suture Snodgrass TIP urethroplasty and 32 boys underwent interrupted-suture Snodgrass TIP urethroplasty. The ethical protocol was followed throughout the period. …”
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Students’ perceptions of endodontic typodont teeth with simulated canals printed from novel materials by Alexander Jon Cresswell-Boyes, Alexander Jon Cresswell-Boyes, Graham Roy Davis, Aylin Baysan

“…IntroductionThis study aimed to investigate students' perceptions of the use of 3D-printed typodonts by implementing a questionnaire and evaluating the students' comparisons between extracted, commercial and 3D-printed teeth.MethodsEthical approval was obtained (QMER20.586/2021) and questionnaire feedback was collected anonymously using an online survey. …”
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Leveraging LLMs and wearables to provide personalized recommendations for enhancing student well-being and academic performance through a proof of concept by Arfan Ahmed, Sarah Aziz, Alaa Abd-alrazaq, Rawan AlSaad, Javaid Sheikh

“…As this technology evolves, ensuring ethical considerations and data privacy remains essential.…”
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In silico tools for mechanical analysis of extra‐ and intra‐luminal artificial urinary sphincters by Gianluca Mazzucco, Paola Pirini, Chiara Giulia Fontanella, Alice Berardo, Maria Vittoria Mascolini, Ilaria Toniolo, Leonardo Marziale, Tommaso Mazzocchi, Gioia Lucarini, Nicolò Spiezia, Emanuele Luigi Carniel

“…Conclusions The activities define and demonstrate the effectiveness of a novel in silico approach to the design and reliability assessment of AUS devices, increasing the investigative possibilities and reducing the time, ethical and economic costs.…”
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Healthcare assessment tools—a valid source of data for pre-hospital care? Usability for ensuring medical care in the event of a disaster by Robert Konrad, Robert Konrad, Denise Schuster, HJ Heppner, HJ Heppner

“…Without adaptation they cannot be used at all or only after concerted efforts to interpret the needs for the care of vulnerable groups in a non-clinical context.DiscussionAn improved use of individual medical data in disaster and civil protection offers many advantages in prevention, diagnostics, therapy and care in the context of disaster medicine, and not only from an ethical point of view. Due to the different tactical procedures and care strategies in disaster medicine, the field of acute care must be clearly separated from the area of evacuation and care of vulnerable groups. …”
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The Developing Progress of Australian Cellular Agriculture in 2023—2024 by TAN Hong-zhuo, FANG Zhong-xiang, YI Cui-ping

“…Cellular agriculture would provide an opportunity to diversify our food system, is expected to improve the sustainability of food supply, and can reduce ethical and moral issues associated with over-consuming animal-based foods. …”
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