The Tissue-Selective Estrogen Complex (Bazedoxifene/Conjugated Estrogens) for the Treatment of Menopause by Stefano Lello, Anna Capozzi, Giovanni Scambia

“…The tissue-selective estrogen complex (TSEC) pairs conjugated estrogens (CE) with a selective estrogen receptor modulator (SERM), bazedoxifene acetate (BZA). …”
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Estrogen Induces Metastatic Potential of Papillary Thyroid Cancer Cells through Estrogen Receptor α and β by Wenwu Dong, Hao Zhang, Jing Li, Haixia Guan, Liang He, Zhihong Wang, Zhongyan Shan, Weiping Teng

“…PTC cell line BCPAP was evaluated for the presence of estrogen receptor (ER) by western blot analysis. The effects of E2, PPT (a potent ERα-selective agonist), and DPN (a potent ERβ-selective agonist) on modulation of metastatic phenotype were determined by using in vitro scratch wound assay and invasion assay. …”
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Estrogens as Antioxidant Modulators in Human Fertility by A. Mancini, S. Raimondo, M. Persano, C. Di Segni, M. Cammarano, G. Gadotti, A. Silvestrini, A. Pontecorvi, E. Meucci

“…After reviewing the literature on the effects of estrogens in modulation of antioxidant systems, in both sexes, and in different in vivo and in vitro models, we suggest, also on the basis of personal data, that a tamoxifen treatment could be active via an increase in seminal antioxidants.…”
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Design and Synthesis of an Indole-Estrogen Derivative by Figueroa-Valverde Lauro, Díaz-Cedillo Francisco, Rosas-Nexticapa Marcela, Hau-Heredia Lenin, García-Cervera Elodia, Pool-Gómez Eduardo, Sarabia-Alcocer Betty

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Sensing Estrogen with Electrochemical Impedance Spectroscopy by Jing Li, Byung Kun Kim, Kang-Kyun Wang, Ji-Eun Im, Han Nim Choi, Dong-Hwan Kim, Seong In Cho, Won-Yong Lee, Yong-Rok Kim

“…This study demonstrates the application feasibility of electrochemical impedance spectroscopy (EIS) in measuring estrogen (17β-estradiol) in gas phase. The present biosensor gives a linear response (R2=0.999) for 17β-estradiol vapor concentration from 3.7 ng/L to 3.7 × 10−4 ng/L with a limit of detection (3.7 × 10−4 ng/L). …”
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NAFLD, Estrogens, and Physical Exercise: The Animal Model by Jean-Marc Lavoie, Abdolnaser Pighon

“…In addition, the use of the animal model has provided physiological and molecular evidence that exercise training provides estrogens-like protective effects on liver fat accumulation and its consequences. …”
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Revisiting Estrogen: Efficacy and Safety for Postmenopausal Bone Health by Sandra M. Sacco, Wendy E. Ward

“…The rapid decline in endogenous estrogen production that occurs during menopause is associated with significant bone loss and increased risk for fragility fracture. …”
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Post-COVID-19 Neuropathology and Perspectives of Protective Roles of Estrogens by Rodrigo Portes Ureshino, Roberta Sessa Stilhano, Carla Máximo Prado, Louise Newson

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Relationship between Postmenopausal Estrogen Deficiency and Aneurysmal Subarachnoid Hemorrhage by Sadaharu Tabuchi

“…There have been growing bodies of epidemiological and experimental studies which support the hypothesis of a significant relationship between estrogen deficiency and cerebral aneurysm formation with subsequent SAH. …”
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In Vitro Assay to Examine Osteoclast Resorptive Activity Under Estrogen Withdrawal by Cara Fiorino, Safia Omer, Nisha Gandhi, Rene Harrison

“…Here, we establish an in vitro model to investigate the effect of estrogen withdrawal on OCs derived from the mouse macrophage RAW 264.7 cell line in a bone biomimetic microenvironment. …”
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A Review on Sex Steroid Hormone Estrogen Receptors in Mammals and Fish by Eric Amenyogbe, Gang Chen, Zhongliang Wang, Xiaoying Lu, Mingde Lin, Ai Ying Lin

“…Steroid hormones play essential roles in the reproductive biology of vertebrates. Estrogen exercises its effect through estrogen receptors and is not only a female reproductive hormone but acts virtually in all vertebrates, including fish, and is involved in the physiological and pathological states in all males and females. …”
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Age and estrogen-associated reductions in hypoxic ventilatory response and chemosensitivity in female rats by Jessica M. L. Grittner, Rebecca Barok, Edgar Juarez Lopez, Misha Shah, Brendan J. Dougherty

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Assessment and Molecular Actions of Endocrine-Disrupting Chemicals That Interfere with Estrogen Receptor Pathways by Gwenneg Kerdivel, Denis Habauzit, Farzad Pakdel

“…In all vertebrate species, estrogens play a crucial role in the development, growth, and function of reproductive and nonreproductive tissues. …”
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Exploring the Role of Estrogens in Lizard Spermatogenesis through the Study of Clomiphene and FSH Effects by Mariailaria Verderame, Rosaria Scudiero, Ermelinda Limatola

“…Increasing evidence suggests that the primary female sex hormone estrogen plays an active role in this process. This research points out on the role of estrogen during lizard spermatogenesis by using three experimental approaches: (1) exposure to an analogue of nonsteroidal estrogen as Clomiphene citrate that acts both as estrogen agonist and antagonist; (2) exposure to the gonadotropin FSH; and (3) exposures to FSH followed by Clomiphene. …”
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Lnc-DC promotes estrogen independent growth and tamoxifen resistance in breast cancer by Wan-Xin Peng, Pratirodh Koirala, Huaixiang Zhou, Jiahong Jiang, Ziqiang Zhang, Liu Yang, Yin-Yuan Mo

“…Abstract Selective estrogen receptor modulators (SERMs) such as tamoxifen have proven to be effective in the treatment of estrogen receptor (ER) positive breast cancer. …”
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Changes in Gastric Smooth Muscle Cell Contraction during Pregnancy: Effect of Estrogen by Othman A. Al-Shboul, Hanan J. Al-Rshoud, Ahmed N. Al-Dwairi, Mohammad A. Alqudah, Mahmoud A. Alfaqih, Ayman G. Mustafa, Mohammad Jaafar

“…The aim of the current study was to explore the changes in the expression of estrogen receptors (ERs) and examine the effect of estrogen on nitric oxide- (NO-) cyclic guanosine monophosphate (cGMP) pathway and thus relaxation in gastric smooth muscle cells (GSMC) during pregnancy. …”
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Altered thermal preference by preoptic estrogen receptor alpha neurons in postpartum females by Nan Zhang, Meng Yu, Qianru Zhao, Bing Feng, Yue Deng, Jonathan C. Bean, Qingzhuo Liu, Benjamin P. Eappen, Yang He, Kristine M. Conde, Hailan Liu, Yongjie Yang, Longlong Tu, Mengjie Wang, Yongxiang Li, Na Yin, Hesong Liu, Junying Han, Darah Ave Threat, Nathan Xu, Taylor Smiley, Pingwen Xu, Lulu Chen, Tianshu Zeng, Yanlin He, Chunmei Wang

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Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis by Xuhui Liu, Zong-Ping Luo

“…For some time, estrogen has been suspected to play a negative role in anterior cruciate ligament (ACL) fibroblast biosynthesis; however, reports on this issue have been controversial. …”
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S-Glutathionylation of Protein Disulfide Isomerase Regulates Estrogen Receptor α Stability and Function by Ying Xiong, Yefim Manevich, Kenneth D. Tew, Danyelle M. Townsend

“…PDI is a molecular chaperone for estrogen receptor alpha (ERα). Our present data show in breast cancer cells that S-glutathionylation of PDI interferes with its chaperone activity and abolishes its capacity to form a complex with ERα. …”
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The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors by Jiajie Tu, Huan Yang, Lei Jiang, Yu Chen, Yu Chen, Zhe Li, Lei Li, Yuanyuan Zhang, Xiaochun Chen, He Chen, Zhiying Yu

“…The pathogenesis of ovarian and endometrial cancers is closely associated with estrogen-related pathways. These estrogen-dependent tumors seriously threaten the health and quality of life in women. …”
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