Evaluating the Efficacy of Combined Intravaginal Estriol Therapy and Kegel Exercises in Managing Menopausal Atrophic Vulvovaginitis by Lucian Șerbănescu, Vadym Rotar, Dragoș Brezeanu, Sebastian Mirea, Elena-Valentina Ionescu, Paris Ionescu

“…Standard treatment involves systemic estrogen replacement therapy (HRT) and localized estrogen treatments, such as estriol. …”
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Strategies for preventing and managing osteoporosis in elderly breast cancer patients undergoing aromatase inhibitor therapy by Andi Tian, Chunyu Zhang

“…The development and progression of breast cancer are closely linked to estrogen levels. For patients with estrogen receptor-positive breast cancer, endocrine therapy targeting estrogen pathways remains a cornerstone of postoperative treatment. …”
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Menopausal Hormone Therapy: Its Role in the Prevention of Cardiovascular Diseases and the Risk of Breast Cancer in Women by Tam Thai Thanh Tran, Thu Minh Phung, Anh Thi Mai Do, Quynh Tran Mai Ly, Tin Hoang Nguyen

“…However, estrogen metabolism plays a crucial role in the genotoxic pathway that leads to breast cancer. …”
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Decreased Expression of GPER1 Gene and Protein in Goiter by Raquel Weber, Ana Paula Santin Bertoni, Laura Walter Bessestil, Ilma Simoni Brum, Tania Weber Furlanetto

“…Goiter is more common in women, suggesting that estrogen could be involved in its physiopathology. …”
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The effect of soy isoflavones in brain development: the emerging role of multiple signaling pathways and future perspectives by Winda Ariyani, Noriyuki Koibuchi

“…Endogenous estrogen plays a crucial role in brain development through binding to estrogen receptors (ERs) or G protein-coupled estrogen receptors 1 (GPER1) and regulates morphogenesis, migration, functional maturation, and intracellular metabolism of neurons and glial cells. …”
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Molecular docking of phytosterols in Stenochlaena palustris as anti-breast cancer by Dona Marisa, Lisda Hayatie, Siti Juliati, Eko Suhartono, Noer Komari

“…Objective: The objective of this study is to evaluate the potential of phytosterols found in S. palustris to act as estrogen receptor (ER) inhibitors. Methods: Phytosterols (alpha-tocopherol, beta-sitosterol, campesterol, stigmasterol, fucosterol) were docked to estrogen receptor (PDB ID: 7KBS). …”
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Computational studies and structural insights for discovery of potential natural aromatase modulators for hormone-dependent breast cancer by Snehal Aditya Arvindekar, Sanket Rathod, Prafulla Balkrishna Choudhari, Pradnya Kiran Mane, Aditya Umesh Arvindekar, Suraj Narayan Mali, Bapu Thorat

“…Introduction: The aromatase enzyme plays an important role in the progress of hormone-dependent breast cancer, especially in estrogen receptor-positive (ER+) breast cancers. In case of postmenopausal women, the aromatization of androstenedione to estrone in adipose tissue is the most important source of estrogen. …”
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Breast Cancer Series: Hormone Therapy by Karen C. Daily, Martha C. Monroe

“…Women who are at high risk of getting breast cancer and women who have had breast cancer may be prescribed daily oral medications to block the estrogen receptor site or decrease the production of estrogen. …”
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Breast Cancer Series: Hormone Therapy by Karen C. Daily, Martha C. Monroe

“…Women who are at high risk of getting breast cancer and women who have had breast cancer may be prescribed daily oral medications to block the estrogen receptor site or decrease the production of estrogen. …”
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Synthesis and Antitumor Activity of Novel Pyridoxine-Based Bioisosteric Analogs of trans-Stilbenes by Mikhail V. Pugachev, Thang T. N. Nguyen, Timur M. Bulatov, Roman S. Pavelyev, Alfia G. Iksanova, Oksana V. Bondar, Konstantin V. Balakin, Yurii G. Shtyrlin

“…Two compounds demonstrated high activity against the estrogen-dependent MCF-7 (breast cancer) cell line with IC50 in the range of 1.9–7.9 µM and very good selectivity for other studied normal and tumor cells, including the estrogen receptor negative MDA-MB-231 breast cancer cells. …”
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17α-Ethynyl-5α-androstane-3α, 17β-diol Treatment of MNU-Induced Mammary Cancer in Rats by Clarence N. Ahlem, James M. Frincke, Steven K. White, Christopher L. Reading, Richard J. Trauger, Rajkumar Lakshmanaswamy

“…N-methyl-N-nitrosourea (MNU) induces estrogen-dependent mammary tumors in female Lewis rats. …”
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Association between Serum Trace Elements Levels, Steroid Concentrations, and Reproductive Disorders in Ewes and Does by Derar Derar, Ahmed Ali, Tariq Almundarij, Essam Abd-Elmoniem, Tamim Alhassun, Moustafa Zeitoun

“…Ewes and goats with estrogen-dominant reproductive disorders had higher Se (P=0.01), Fe (P=0.03), and Zn (P=0.01) compared with the control group. …”
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The Anti-Inflammatory, Phytoestrogenic, and Antioxidative Role of Labisia pumila in Prevention of Postmenopausal Osteoporosis by M. E. Nadia, A. S. Nazrun, M. Norazlina, N. M. Isa, M. Norliza, S. Ima Nirwana

“…Estrogen is able to suppress production of proinflammatory cytokines such as IL-1, IL-6, IL-7, and TNF-α. …”
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Jingui Shenqi Wan alleviates bone loss induced by primary osteoporosis by inhibiting osteoblast pyroptosis by Yuwangxuan Qian, Yihe Yu, Fan Yang, Qixing Liang, Dan Xu, Jiaxiang Chen, Xueqin Hu

“…Conclusion JGSQW may effectively mitigate the progression of estrogen deficiency-induced PMOP by inhibiting the dysregulated activation of osteoblast pyroptosis.…”
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Benign Metastasizing Leiomyoma: A Rare Type of Lung Metastases—Two Case Reports and Review of the Literature by Rokana Taftaf, Sandra Starnes, Jiang Wang, Ralph Shipley, Tariq Namad, Rana Khaled, Nagla Abdel Karim

“…Additional stains, such as estrogen/progesterone receptors, may need to be done to confirm the diagnosis.…”
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MiR-155-Mediated Deregulation of GPER1 Plays an Important Role in the Gender Differences Related to Inflammatory Bowel Disease by Xiaojuan Shao, Jintao Li, Fumin Xu, Dongfeng Chen, Kaijun Liu

“…The objective of this study was to investigate the role of the estrogen receptors and miR-155 in the pathogenesis of IBD. …”
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A Mathematical Model for DNA Damage and Repair by Philip S. Crooke, Fritz F. Parl

“…In this paper, we created a combined mathematical model for the formation of DNA adducts from oxidative estrogen metabolism followed by base excision repair (BER) of these adducts. …”
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Postmenopausal Deep Infiltrating Endometriosis of the Colon: Rare Location and Novel Medical Therapy by Benjamin M. Snyder, Joseph W. Beets, Bruce A. Lessey, Samuel R. W. Horton, Gary A. Abrams

“…Instead of surgery, we prescribed a novel medical therapeutic approach using conjugated estrogen-bazedoxifene to antagonize the proliferative effects of estrogen on endometrial tissue. …”
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Labial Fusion in Childhood: Management and Treatment Strategies by Ayşe Filiz GÖKMEN KARASU, Çağlar ÇETİN

“…However if the condition results in complications such as urinary retention, recurrent urinary tract infection or vaginitis topical therapy with estrogen or bethametazone is the first treatment option. …”
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Physical activities and breast cancer: a Mendelian randomization study by Lishan Ding, Qingliang Chen, Hao Liang, Meng Shen, Ming Zheng, Zhaojun Li

“…The cases were further categorized based on estrogen receptor status into estrogen receptor-positive breast cancer (ER+ BC) and estrogen receptor-negative breast cancer (ER– BC). …”
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