A Rare Case of Primary Amenorrhea with Two Etiologies, Hypothalamic Amenorrhea, Transverse Vaginal Septum, and No Hematocolpos by Firouzeh Ghaffari, Fatemeh Keikha, Arezoo Arabipoor

“…In our institute, after two courses of estrogen and progesterone, sonography revealed hematocolpos, while, under anesthesia, transverse vaginal septum was resected. …”
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MRI Features of Malignant Transformation of Pelvic Endometriosis: A Systematic Review by Shirin Yaghoobpoor

“… Background: Endometriosis is a benign gynecologic condition that is estrogen-dependent. Malignant transformation is one of the complications of endometriosis; it can affect the woman's ovarian and extra-ovarian regions. …”
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Dedifferentiated Leiomyosarcoma of the Uterus with Heterologous Elements: A Potential Diagnostic Pitfall by Kojo R. Rawish, Oluwole Fadare

“…The original tumor was a high-grade leiomyosarcoma with large low-grade and leiomyoma-like areas and whose constituent cells displayed intense nuclear immunoreactivity for both estrogen receptor (ER) and progesterone receptor (PR) in approximately 30% of cells. …”
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Ovarian Basaloid Carcinoma with Shadow Cell Differentiation by Michal Zamecnik, Daniel Jando, Peter Kascak

“…Cytokeratin 7 and CA125 were positive in scattered cells of the lesion. Estrogen and progesterone receptor, vimentin, and p53 were negative. …”
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Natural History of Invasive Papillary Breast Carcinoma Followed for 10 Years: A Case Report and Literature Review by Yong Joon Suh, Hyukjai Shin, Tae Jung Kwon

“…Immunohistochemistry results, corresponding to biopsies taken at subsequent examinations, have remained unaltered since 2006. The tumor was estrogen/progesterone receptor-positive and C-erbB2 expression was not detected. …”
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Association between long-term ambient air pollution exposure and the incidence of breast cancer: A meta-analysis based on updated evidence by Ruohan Wang, Peihan Wang, Yongkang Zhou, Yinan Wang, Chengdong Xu, Zhenbo Wang, Wei Wang

“…The associations of NO2, PM2.5, and PM10 with estrogen/progesterone receptor-positive (ER+/PR+) breast cancer were not significantly different from those with estrogen/progesterone receptor-negative (ER–/PR–) breast cancer. …”
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Erythema Nodosum and Pyoderma Gangrenosum in 50 Patients with Crohn’s Disease by Hugh J Freeman

“…This suggests that some components of the inflammatory process in Crohn's disease may be modulated by estrogen-mediated events, particularly in adolescents and young adults.…”
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TMT-based quantitative proteomics reveals the genetic mechanisms of secondary hair follicle development in fine-wool sheep. by Li-Xia Qiu, Qian Yu, Hua-Qian Zhou, Wen-Hua Fan, Jing-Jing Zheng, Yong-Lin Yang, Wen-Zhe Zhang, Xin Cao, Hua Yang

“…Focal adhesion, ECM-receptor interaction, and the estrogen signaling pathway all played important roles in secondary hair follicle development. …”
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Comparison of In Vitro Endocrine Activity of Phthalates and Alternative Plasticizers by Hélène Moche, Aouatif Chentouf, Sergio Neves, Jean-Marc Corpart, Fabrice Nesslany

“…Effects of these chemicals on 3 common mechanisms of endocrine disruption, i.e., interaction with estrogen receptors (ER), androgen receptors (AR), or steroidogenesis, were studied using extensively used in vitro methods. …”
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Exploring Fragment Adding Strategies to Enhance Molecule Pretraining in AI-Driven Drug Discovery by Zhaoxu Meng, Cheng Chen, Xuan Zhang, Wei Zhao, Xuefeng Cui

“…Consequently, we have developed a virtual screening protocol that focuses on identifying estrogen receptor alpha binders on a nucleus receptor. …”
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MPTP Neurotoxicity and Testosterone Induce Dendritic Remodeling of Striatal Medium Spiny Neurons in the C57Bl/6 Mouse by Eleni Antzoulatos, Michael W. Jakowec, Giselle M. Petzinger, Ruth I. Wood

“…Nigrostriatal damage is increased in males relative to females. While estrogen is neuroprotective in females, less is known about potential protective effects of testosterone in males. …”
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A Follow-Up Report of an Infant Born to a Mother Receiving Tamoxifen by Yuki Okada, Daisuke Hitaka, Takahiro Kido, Yu Kanai, Kumi Konishi, Kosuke Doki, Nobuko Katayama, Masato Homma, Yayoi Miyazono, Hidetoshi Takada

“…Tamoxifen, an estrogen receptor antagonist, is contraindicated in pregnant women due to its teratogenic activity. …”
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Green Synthesis of New Pyrrolo [1,2-a] quinoxalines as Antiproliferative Agents in GPER-expressing Breast Cancer Cells by Gabriele Carullo, Sarah Mazzotta, Francesca Giordano, Francesca Aiello

“…4,5-Dihydropyrrolo [1,2-a]quinoxalines are interesting druggable scaffolds, with multifaceted biological properties, including anticancer properties targeting the G protein-coupled estrogen receptor 1 (GPER). In this work, the synthesis and preliminary antiproliferative activity of a small set of new 4,5-dihydropyrrolo[1,2-a]quinoxalines (18-20) and pyrrolo[1,2-a]quinoxalines (21, 22) has been reported, inspired by known antiproliferative agents (G-1, G-15, and G-36). …”
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Effect of Humulus lupulus L. (Hop) on Postmenopausal Sexual Dysfunction: A Randomized Clinical Trial by Zahra Vahedpoorfard, Samira Ferdosi, Habibollah Rahimi, Hossein Motedayyen

“…Female sexual dysfunction is a common distressing problem among women, which may result from reducing circulating endogenous estrogen. Humulus lupulus L. (hop) has antioxidant, anti-inflammatory, anticancer, and estrogenic properties. …”
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Long-Term Followup of Adolescent and Young Adult Females with Hypergonadotropic Hypogonadism by Tsimaris Pantelis, Vrachnis Nikolaos, Iliodromiti Zoe, Deligeoroglou Efthymios

“…Determining the cause of POI is difficult, and it is even harder to deal with problems arising from the paucity of estrogen as well as to draw up the plan for long-term monitoring of these patients. …”
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Endometrioid Adenocarcinoma in the Native Ureter of a Renal Transplant Patient: Case Report and Review of the Literature by Kelly A. Healy, Kenneth J. Carney, Adeboye O. Osunkoya

“…The patient had a history of total abdominal hysterectomy and bilateral salpingo-oophrectomy 14 years prior for menorrhagia and had since been on unopposed estrogen replacement therapy. Workup revealed a filling defect in the native left mid-ureter secondary to a large 2.5-cm ureteral tumor. …”
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Gonadal Hormone Changes with Aging and Their Impact on Chronic Pain by Onella Athnaiel, Nicholas Davidson, Jaskaran Mangat, Ned F. Nasr, Nebojsa Nick Knezevic

“…Women tend to experience less pain with aging compared to their premenopausal years, and this is partially explained by the fact that estrogen enhances pain sensitivity and its decline during menopause decreases it. …”
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Immunity in the Cervix: Interphase between Immune and Cervical Epithelial Cells by Jorgelina Barrios De Tomasi, Michael Makokha Opata, Chishimba Nathan Mowa

“…The immune response, as most biological processes in the female reproductive tract (FRT), is mainly regulated by estrogen and progesterone and their (immune cells) responses vary during different physiological phases of reproduction, such as menstrual cycle, pregnancy, and post menopause. …”
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Reproduction-Associated Hormones and Adult Hippocampal Neurogenesis by Lily Wan, Rou-Jie Huang, Zhao-Hui Luo, Jiao-e Gong, Aihua Pan, Jim Manavis, Xiao-Xin Yan, Bo Xiao

“…The levels of reproduction-associated hormones in females, such as estrogen, progesterone, prolactin, and oxytocin, change dramatically during pregnancy and postpartum. …”
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Co-targeting of metabolism using dietary and pharmacologic approaches reduces breast cancer metastatic burden by Qianying Zuo, Jin Young Yoo, Erik R. Nelson, Matthew J. Sikora, Rebecca B. Riggins, Zeynep Madak-Erdogan

“…Building on previous research that identified metastatic-niche-specific metabolic vulnerabilities, we investigated how a ketogenic diet enhances estrogen receptor (ER)-positive liver metastatic breast cancer’s response to Fulvestrant (Fulv) treatment. …”
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