The carbon cost of impaired welfare on sheep farms by L. Lanzoni, M.C. Reeves, K. Waxenberg, R. Ramsey, A.S. Atzori, J. Bell, R.M. Rees, G. Vignola, C.M. Dwyer

“…The selected poor-welfare scenarios included lameness, gastrointestinal nematodes, blowfly strike, liver fluke, inadequate shelter provision, inadequate feeding during lamb growth and late gestation, and high lamb mortality rate. GHG emissions were estimated “from-cradle-to-farm-gate” using Agrecalc ©, a Life Cycle Assessment tool for the agricultural sector. …”
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Chinese herbal formula Tongxie Yaofang granules for diarrhoea-predominant irritable bowel syndrome: a randomised, double-blind, placebo-controlled, phase II trial by Nicola Robinson, Mei Han, Ling Yan, Vincent Chi Ho Chung, Jian-Ping Liu, Hui-Juan Cao, Shi-Bing Liang, Hong-Jie Cheng, Qiao-Yan Zhang, Yu-Fei Li, Ze-Yu Yu, Ling-Yao Kong, Yan-Mei Cai, Li-Bao An, Bao-Tuan Zhao, Shan-Shan Xu, Nai-Wei Zhang, Bo-Yi Jia, Wei-Fang Liu, Fang Niu, Ba-Teer Wu, Jin-Ming Song, Shu-Xin Jia, Meng-Meng Shi, Xiao-Na Zhang

“…The response rate was not significantly different at week 8 between the two groups (the unadjusted treatment effect estimate (intention-to-treat analysis) was 1.12 (95% CI (0.89, 1.41)), p=0.348). …”
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Supervised Injecting Room Cohort Study (SIRX): study protocol by Lisa Maher, Thomas Kerr, Matthew Hickman, Alexander Thompson, Peter Higgs, Paul Dietze, Paul A Agius, Nick Scott, Daniel O’Keefe, Mark A Stoové, Jack Stone, Dylan Vella-Horne, Ashleigh C Stewart, Amanda Roxburgh, Sione Crawford, Josephine Norman, Zachary Lloyd, Nico Clark

“…Using causal inference methods, analyses will estimate the effect of MSIR exposure (frequent use/infrequent use/no use) on these primary outcomes. …”
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The computerized algorithm for renal assessment improves diagnostic accuracy of renal impairment in hospitalized patients by Chun-You Chen, Te-I. Chang, Cheng-Hsien Chen, Shih-Chang Hsu, Yen-Ling Chu, Nai-Jen Huang, Yuh-Mou Sue, Tso-Hsiao Chen, Po-Hsun Huang, Chung-Te Liu, Hui-Ling Hsieh

“…A SCr level increased > 1.5 times from baseline was defined as AKI. An estimated glomerular filtration rate (eGFR) of < 60 mL/min/1.73 m2 for > 90 days was defined as CKD. …”
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Clinicians’ user experience with health information exchange technologies during simulated medication reconciliation by Himalaya Patel, April Savoy, Steven L. Sanchez, Morgan Traylor, Khoa A. Nguyen, Kenneth S. Boockvar, Vincent S. Fan, Emily R. Locke, Bryan Gibson, Amanda S. Mixon, Susan H. Byerly, David A. Haggstrom, Teresa M. Damush, Michael Weiner, Alissa L. Russ-Jara

“…Overall, participant-rated ease of use and utility (M [SD]) were 4.0 (1.7)—a point-estimate grade of D (“Fair”)—and 4.0 (1.6), respectively. …”
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The Prevalence of Celiac Disease-Specific Auto-Antibodies in Type 1 Diabetes in a Moroccan Population by Ider Oujamaa, Majda Sebbani, Lahcen Elmoumou, Aïcha Bourrahouate, Rabiy El Qadiry, Soufian El Moussaoui, Imane Ait Sab, Mohamed Sbihi, Laila Ennazk, Ghizlane El Mghari-Tabib, Nawal El Ansari, Hicham Baizri, Mohamed Amine, Brahim Admou

“…The prevalence of CD-specific auto-antibodies was estimated to be 9.1% (IC = 95%), with 25 positive cases in tTGA and EMA testing. …”
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Neural Correlates of Balance Skill Learning in Young and Older Individuals: A Systematic Review and Meta-analysis by Lisanne B. M. Bakker, Claudine J. C. Lamoth, Tomas Vetrovsky, Markus Gruber, Simone R. Caljouw, Ward Nieboer, Wolfgang Taube, Jaap H. van Dieën, Urs Granacher, Tibor Hortobágyi

“…Methods We determined the effects of acute (1–3 sessions) and chronic (> 3 sessions) balance skill training on balance in the trained and in untrained, transfer balance tasks through a systematic review and quantified these effects by robust variance estimation meta-analysis in combination with meta-regression. …”
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Engaging the private sector as part of HIV pre-exposure prophylaxis service delivery in Vietnam: a comparative analysis of uptake, persistence and HIV seroconversion from 2018 to 2... by Bao Ngoc Vu, Kimberly Green, Huong Phan, Long Tran, Phuong Phan, Tham Tran, Linh Doan, Yen Vu, Chau Pham, Dao Nguyen, Anh Doan, Trang Ngo, Phuong Tran, Vuong Nguyen, Bieu Nguyen, Thai Phan, Ha Nguyen

“…We used the Kaplan-Meier time-to-event approach to estimate PrEP persistence and mixed-effects logistic regression analysis to assess factors associated with the PrEP persistence.ResultsFrom October 2017 to September 2023, 29,944 individuals initiated PrEP, and among these, 79.3% started PrEP at a private sector clinic while 20.7% initiated in a public sector clinic. …”
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Single-cell profiling of SLC family transporters: uncovering the role of SLC7A1 in osteosarcoma by Yan Liao, Junkai Chen, Hao Yao, Ting Zheng, Jian Tu, Weidong Chen, ZeHao Guo, Yutong Zou, Lili Wen, Xianbiao Xie

“…Survival analysis and ROC analysis evaluated the validity of the prognostic signature. The ESTIMATE and CIBERSORT Packages were utilized to assess the immune infiltration status. …”
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The effect of the relative dose intensity of chemoradiotherapy on the effectiveness of therapy of locally advanced unresectable non-small cell lung cancer by A. E. Glukhareva, G. V. Afonin, I. V. Kolobaev, L. Yu. Grivtsova, S. A. Ivanov, A.  D.  Kaprin

“…The purpose of the study. To estimate the number of patients with the preservation of relative dose intensity (RDI) ≥ 80 % of first-line antitumor therapy in patients with unresectable non-small cell lung cancer (NSCLC), and to compare the effectiveness of therapy in groups with optimal and lower RDI.Patients and methods. …”
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Clonal hematopoiesis of indeterminate potential is a risk factor of gastric cancer: A Prospective Cohort in UK Biobank study by Zhihui Xi, Huolun Feng, Kunling Chen, Xin Guo, Dandan Zhu, Jiabin Zheng, Yong Li

“…Main outcomes and measures: Odds ratio (OR) of CHIP with gastric cancer risk was estimated using multivariable logistic regression models. …”
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Serum uric acid/creatinine ratio and 1-year stroke recurrence in patient with acute ischemic stroke and abnormal renal function: results from the Xi'an stroke registry study of Chi... by Zhongzhong Liu, Zhongzhong Liu, Zhongzhong Liu, Dandan Zhang, Dandan Zhang, Lingxia Zeng, Weiyan Guo, Qingli Lu, Qingli Lu, Zhen Lei, Yunlong Hao, Pei Liu, Pei Liu, Tong Liu, Tong Liu, Linna Peng, Linna Peng, Qiaoqiao Chang, Qiaoqiao Chang, Mi Zhang, Mi Zhang, Xuemei Lin, Xuemei Lin, Fang Wang, Fang Wang, Songdi Wu, Songdi Wu, Songdi Wu, Songdi Wu

“…Abnormal Renal function was defined by the estimated glomerular filtration rate (eGFR) &lt; 90 mL/min/1.73 m2. …”
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Toward accurate prediction of carbon dioxide (CO2) compressibility factor using tree-based intelligent schemes (XGBoost and LightGBM) and equations of state by Behnam Amiri-Ramsheh, Aydin Larestani, Saeid Atashrouz, Elnaz Nasirzadeh, Meriem Essakhraoui, Ali Abedi, Mehdi Ostadhassan, Ahmad Mohaddespour, Abdolhossein Hemmati-Sarapardeh

“…In this study, two powerful and robust tree-based machine learning (ML) algorithms, namely light gradient boosted machine (LightGBM) and extreme gradient boosting (XGBoost) were utilized to precisely estimate CO2 Z-factor. To this end, a comprehensive databank from the literature is employed, which contains 2118 data points over extensive ranges of pressures and temperatures. …”
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Carbon cycle and climate feedbacks under CO₂ and non-CO₂ overshoot pathways by I. Melnikova, I. Melnikova, P. Ciais, K. Tanaka, K. Tanaka, H. Shiogama, K. Tachiiri, K. Tachiiri, T. Yokohata, O. Boucher

“…<p>Reducing emissions of non-carbon dioxide (<span class="inline-formula">CO₂</span>) greenhouse gases (GHGs), such as methane (<span class="inline-formula">CH₄</span>) and nitrous oxide (<span class="inline-formula">N₂O</span>), complements <span class="inline-formula">CO₂</span> mitigation in limiting global warming. However, estimating carbon–climate feedback for these gases remains fraught with uncertainties, especially under overshoot scenarios. …”
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The prognostic value of the 8th American Joint Committee on cancer anatomic and prognostic stage groups for penile cancer: A multicenter collaboration study by Xueying Li, Yepeng Guo, Antonio Augusto Ornellas, Jiun-Hung Geng, Yonghong Li, Wayne Lam, Yabing Cao, Zhuowei Liu, Hui Han, Fangjian Zhou, Zaishang Li

“…Kaplan–Meier plots were used to estimate the disease-specific survival (DSS) of the patients. …”
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Dose-response associations of device-measured sleep regularity and duration with incident dementia in 82391 UK adults by Wenxin Bian, Raaj K. Biswas, Matthew N. Ahmadi, Yu Sun Bin, Svetlana Postnova, Andrew J. K. Phillips, Nicholas A. Koemel, Jean-Philippe Chaput, Shantha M. W. Rajaratnam, Peter A. Cistulli, Emmanuel Stamatakis

“…We used Cox proportional hazard models to estimate the hazard ratios (HRs) for incident dementia after adjustment for common demographic and clinical covariates. …”
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Incidence and contributing factors of dementia among people living with HIV in British Columbia, Canada, from 2002 to 2016: a retrospective cohort study by Rolando Barrios, Julio S G Montaner, Silvia Guillemi, Ni Gusti Ayu Nanditha, Viviane D Lima, Thomas L Patterson, Fidel Vila-Rodriguez, William G Honer, Jason Trigg, Hasan Nathani, Sara Shayegi-Nik, Weijia Yin, Alejandra Fonseca, Bronhilda T Takeh

“…Introduction Dementia is a progressive and debilitating disease, and people living with HIV (PLWH) often develop dementia much earlier than those not living with HIV. We estimated the incidence and prevalence of dementia and identified its key risk factors in a cohort of PLWH in British Columbia, Canada.Methods This retrospective cohort study used data from the Seek and Treat for Optimal Prevention of HIV/AIDS study. …”
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Concentrations and human health risks attributed to potentially toxic elements (PTEs) in water resources in China: Systematic review and meta-analysis by Xiaomei Hui, Anhui Li, Sheng Chang, Aihua Wang, Lu Wang, Chao Li

“…Human health risk assessment due to PTEs in water from ingestion and dermal contact pathways was estimated using target hazard quintet (THQ) and carcinogenic (CR) in adult males and female consumers in China. …”
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Safety and efficacy of telaprevir in treatment of a chronic hepatitis C in patients of the Russian population included in early access program study by D. T. Abrurakhmanov, V. G. Morozov, I. G. Nikitin, P. O. Bogomolov, N. I. Geyvandova, Ye. N. Bessonova, I. G. Bakulin, V. A. Isakov, K. V. Zhdanov, M. V. Mayevskaya, Ye. A. Nurmukhametova, E. Z. Burnevich, Ye. V. Chesnokov, V. D. Pasechnikov, A. Hill, I. Lonjon-Domanec, S. N. Kizhlo

“…HEP3002 is the international early access program of efficacy and safety estimation of telaprevir in combination to peginterferon alpha and ribavirin for patients with severe fibrosis or liver cirrhosis caused by hepatitis C virus (HCV) genotype 1. …”
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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…Sample size Separate calculations for model development and validation cohorts, from literature estimates of detrusor overactivity, bladder outlet obstruction and detrusor underactivity prevalences of 57%, 31% and 16%, respectively. …”
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