Derivation of a simple risk calculator for predicting clinical worsening in patients with pulmonary hypertension due to interstitial lung disease by K. El-Kersh, R. Bag, N. Bhatt, C. King, A. Waxman, F. Rischard, H. Kim, D. Cella, E. Shen, SD Nathan

“…For the total point score models, the estimated c-indices were 0.703 (95% CI: 0.635, 0.783) and 0.683 (95% CI: 0.612, 0.761) for the invasive and non-invasive model, respectively. …”
Get full text

Association between the atherogenic index of plasma and non-alcoholic fatty liver disease in Korean pregnant women: secondary analysis of a prospective cohort study by Rong Shuai, Yuxing He, Dongqian Yang, Yingying Zhang, Li Zhang

“…Logistic regression models were used to estimate the relationship between AIP and NAFLD. Subgroup and sensitivity analyses were conducted to explore the stability of this relationship. …”
Get full text

Evaluation of choices and time spent on an open online elective course by undergraduate medical students during the COVID-19 pandemic by Z Mfeka, A Turner, J E Wolvaardt, D Muganhiri

“…Data were collected and analysed from three primary sources: registration data from LinkedIn Learning, data from the Foundation for Professional Development, and self-reported estimates by students of the average time spent on selected courses. …”
Get full text

The Comparison of the Kidney Effects of Dipeptidyl Peptidase 4 Inhibitors and Glucagon-Like Peptide 1 Agonist-Administered Concomitant with Sodium-Glucose Cotransporter 2 Inhibitor... by Kazuo Kobayashi, Masao Toyoda, Nobuo Hatori, Kazuyoshi Sato, Masaaki Miyakawa, Kouichi Tamura, Akira Kanamori

“…In the matched model including 86 cases per group, the decrease in the logarithmic value of the ACR and rate of reduction in the estimated glomerular filtration rate (eGFR; mL/min/1.73 m2) of the GLP1Ra group showed no significant difference from those in the DPP4i group (−0.12±0.48 vs. −0.13±0.45 and −2.3±18.5 vs. −6.2±13.8, respectively, P=0.10). …”
Get full text

Discharge against Medical Advice (DAMA) from an Emergency Department of a Tertiary Care Hospital in Saudi Arabia by Ashraf El-Metwally, Nesreen Suliman Alwallan, Ali Amin Alnajjar, Nida Zahid, Khalid Alahmary, Paivi Toivola

“…Future studies should assess the socioeconomic status of the patients and estimate the cost that is incurred by the patients.…”
Get full text

Patellofemoral Joint Loading During the Performance of the Forward and Side Lunge with Step Height Variations by Rafael Escamilla, Naiquan Zheng, Toran D MacLeod, Rodney Imamura, Kevin E. Wilk, Shangcheng Wang, Irv Rubenstein, Kyle Yamashiro, Glenn S. Fleisig

“… # Hypothesis/Purpose The purpose was to quantify, via calculated estimates, patellofemoral force and stress between two lunge type variations (forward lunge versus side lunge) and between two step height variations (ground level versus 10 cm platform). …”
Get full text

Dataset on electricity usage measurement for lower-to-middle-income primary and secondary schools in Western Cape, South AfricaMendeley Data by Jason Avron Samuels, Terhemba Michael-Ahile, M. J. (Thinus) Booysen

“…With over 24,000 public primary and secondary schools using an estimated 3.5 TWh annually, the collective utility expense amounts to ZAR 5.0 billion (approximately US$ 330 million). …”
Get full text

Brief Report: Not Created Equal: Survival Differences by KRAS Mutation Subtype in NSCLC Treated With Immunotherapy by Lova Sun, MD, MSCE, Yunyun Zhou, PhD, Elizabeth A. Handorf, PhD, Hossein Borghaei, DO, Jessica Bauman, MD, Charu Aggarwal, MD

“…Within PD-L1 expression subgroups (<1%, 1%–49%, ≥50%), Cox multivariable regression was used to evaluate the association between KRASm subtypes (G12C, G12V, G12D, other KRASm) and overall survival, estimated using Kaplan-Meier methodology. Results: Among the 1539 patients, 819 patients were KRAS wild type (KRASwt) and 720 were KRASm (296 KRAS G12C, 143 KRAS G12V, 97 KRAS G12D, 184 other KRASm). …”
Get full text

Characterisation of coastal reef fish assemblages across an estuarine-urbanisation gradient using underwater visual census and environmental DNA metabarcoding by Yu-De Pei, Joseph Heard, Wenqian Xu, Shara K.K. Leung, Charmaine C.M. Yung, Alex S.J. Wyatt

“…Nevertheless, we recorded 17 % of the known fish diversity and provided a comprehensive picture of patterns in fish diversity across the gradient, despite limited sampling effort. Visual estimates of fish generic richness were reduced by 1.6- to 3-fold under the highly turbid estuarine conditions found around Lantau compared to other regions. …”
Get full text

Development and evaluation of patient-centred polygenic risk score reports for glaucoma screening by Georgina L Hollitt, Mark M Hassall, Owen M Siggs, Jamie E Craig, Emmanuelle Souzeau

“…Abstract Background Polygenic risk scores (PRS), which provide an individual probabilistic estimate of genetic susceptibility to develop a disease, have shown effective risk stratification for glaucoma onset. …”
Get full text

Evaluation of the Level of Salivary sHLA-G in Children Aged 3–5 Years with or without Dental Caries by Mansoureh Bijani, Amrollah Mostafazadeh, Mina Motallebnejad, Ali Bijani, Roghiyeh Pourbagher, Samaneh Gharekhani

“…As dental caries is a bacterial infectious disease, the host immune system parameters including soluble human leukocyte antigen-G (sHLA-G) are essential factors in estimating dental caries. The study aimed to investigate and compare the concentration of sHLA-G in the saliva of children with or without dental caries. …”
Get full text

Relationship of monocyte to high-density lipoprotein ratio (MHR) and other inflammatory biomarkers with sarcopenia: a population-based study by Zhiwei Xue, Jian Cao, Jianhui Mou, Rui Wang, Peng Liu

“…Additionally, AUC values and ROC curves were used to assess the predictive effectiveness of ln MHR and other markers (ln SII, ln NLR, ln NHHR, ln MHR + ln SII, ln MHR + ln NHHR, and ln MHR + ln NLR). The bootstrap estimated 95% Cl was shown with the AUC. Results In the fully adjusted model, ln SII, ln NLR, ln NHHR, ln MHR, ln MHR + ln SII, ln MHR + ln NHHR, and ln MHR + ln NLR were positively associated with low muscle mass (ln SII: OR = 1.59 [1.37–1.84]; ln NLR: OR = 1.35 [1.13–1.60]; ln NHHR: OR = 1.49[1.27–1.75]; ln MHR: OR = 1.98 [1.68–2.33]; ln MHR + ln SII: OR = 1.61 [1.46–1.79]; ln MHR + ln NHHR: OR = 1.42 [1.29–1.56]; ln MHR + ln NLR: OR = 1.58 [1.41–1.78]). …”
Get full text

The anthropogenic activities in Makere north forest reserve in Tanzania and implications to conservation by Eberehard Daudi, Hussein Luswaga, Pensia Mapunda, Hamisi Nchimbi

“…This study aimed to estimate the extent and diversity of direct anthropogenic activities in Makere North Forest Reserve (MNFR) Tanzania and its implications for conservation. …”
Get full text

Regional Differences of Digital Rural Construction in China and Driving Factors by Zeng Yongming, Zhong Zikang

“…Combined with the advantages of Geographically and Temporally Weighted Regression model for local parameter estimation, this study verified that different driving factors had significant spatial heterogeneity effects on the construction of digital rural areas in different county-level units. …”
Get full text

Medicinal plants with anti-SARS-CoV activity repurposing for treatment of COVID-19 infection: A systematic review and meta-analysis by EBENEZER OLUWAKEMI, BODEDE OLUSOLA, AWOLADE PAUL, JORDAAN MARYAM A., OGUNSAKIN ROPO E., SHAPI MICHAEL

“…According to subgroup analysis, the substantial heterogeneity of the estimated mean based on the IC50 values reporting the most potent anti-SARS-CoV 3C--like protease (3CLpro) inhibitors (10.07 %, p < 0.0001), was significantly higher compared to the most active anti-SARS-CoV papain-like protease (PLpro) inhibitors (6.12 %, p < 0.0001). …”
Get full text

Space-time Characteristics of 16 PM2.5-bound Phthalates (PAEs) in Ambient Air from Shanghai: Profiles, Sources, Meteorological Effects, and Exposure Risks by Janvier Munyaneza, Md Faysal Hossain, Qilong Jia, Yusen Duan, Guangli Xiu

“…Among population groups, an elevated daily intake (EDI) ranging from 1.04 to 27.95 ng kgBWt−1 day−1 was found for toddlers, with the highest estimated hazard index of 1.5 × 10−2.…”
Get full text

Phenolic Content and Antioxidant and Antimicrobial Activities of Malva sylvestris L., Malva oxyloba Boiss., Malva parviflora L., and Malva aegyptia L. Leaves Extract by Khalid A. Shadid, Ashok K. Shakya, Rajashri R. Naik, Nidal Jaradat, Husni S. Farah, Naeem Shalan, Nooman A. Khalaf, Ghaleb A. Oriquat

“…By utilizing the Folin–Ciocalteu procedure and gallic acid as a reference molecule, the phenolic contents were estimated. In addition, the broth microdilution method was used to evaluate four plants’ 16 extracts, and the DPPH (2,2-diphenyl-1-picrylhydrazyl) method was utilized to assess the abovementioned extracts against oxidative stress. …”
Get full text

Association of Depression with Age at Natural Menopause: A Cross-Sectional Analysis with NHANES Data by An S, Ren S, Ma J, Zhang Y

“…After full adjustment in multivariate logistic regression, it was estimated that each one-unit increase in the PHQ-9 score was associated with a 7% increased risk of early menopause (OR = 1.07, 95% CI = 1.02– 1.12). …”
Get full text

Polyphénols et activités antioxydantes des fruits de Grewia spp. consommés par les bonobos à Luikotale, R.D. Congo by C‑Désiré Musuyu Muganza, Ulrich Maloueki, Kumugo S‑P Ndimbo, Ikombe N Bondjengo, Mukulire J Malekani, Nseu B Mbomba, Barbara Fruth

“…Aussi, nous sommes-nous proposés d’évaluer le potentiel antioxydant et les polyphénols présents dans les fruits mûrs de cinq espèces du genre Grewia afin d’estimer de façon comparative les potentiels bénéfices des fruits des différentes espèces pour la santé des bonobos. …”
Get full text

Association between Helicobacter pylori Infection and Occurrence of Anemia among Pregnant Women Attending Antenatal Care in Kulito Health Center, Halaba Zone, South Ethiopia, 2018 by Bahredin Abdella, Mohammed Ibrahim, Iyasu Tadesse, Kalkidan Hassen, Mekonnin Tesfa

“…Nearly 50% of the world’s population is estimated to be infected with Helicobacter pylori (HP). …”
Get full text