Joint effect of modifiable risk factors on Parkinson’s disease: a large-scale longitudinal study by Panlong Li, Xirui Zhu, Min Liu, Yanfeng Wang, Chun Huang, Junwei Sun, Shan Tian, Yuna Li, Yuan Qiao, Junting Yang, Shanshan Cao, Chaohua Cong, Lei Zhao, Jingjing Su, Dandan Tian

“…Population attributable fraction (PAF) was estimated to quantify contribution ratio of risk factors in different domains to the occurrence of PD.ResultsMultiple risk factors significantly (p < 1.96 × 10−4) associated with PD was observed. …”
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Clinical and biochemical characteristics for patients with polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes syndrome: a pilot observational study by Pei Li, Ye Zhang, Li-Min Luo, Wen-Qing Wang, Jing Li, Yan Cheng, Xiao Dang, Yang Chen, Wei Jiang

“…Aspartate aminotransferase, total protein, and estimated glomerular filtration rate levels were increased, while creatinine and uric acid levels were reduced post-therapy in patients with POEMS syndrome.ConclusionPatients with POEMS syndrome had impaired liver and renal function, and effective therapy might partly repair the liver and renal dysfunction.…”
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Different Activity of the Biological Axis VEGF-Flt-1 (fms-Like Tyrosine Kinase 1) and CXC Chemokines between Pulmonary Sarcoidosis and Idiopathic Pulmonary Fibrosis: A Bronchoalveo... by Katerina M. Antoniou, Giannoula Soufla, Athanasia Proklou, George Margaritopoulos, Christiana Choulaki, Rena Lymbouridou, Katerina D. Samara, Demetrios A. Spandidos, Nikolaos M. Siafakas

“…Our aim was to further investigate the aforementioned finding by measuring the expression of different chemokines in granulomatous and fibrotic diseases. We estimated the levels of vascular endothelial growth factor (VEGF) and its high-affinity receptor, Flt-1 (fms-like tyrosine kinase 1), in bronchoalveolar lavage fluid (BALF) of patients with IPF and pulmonary sarcoidosis. …”
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Oral Cyclophosphamide for Patients With Metastatic Castration-Resistant Prostate Cancer in a Scenario of Limited Health Care Resources by Diana del Cisne Pineda, Gabriel Berlingieri Polho, Yumi Ricucci Shinkado, Gustavo Alves Contado, Nathalia de Souza Crusoe, Vivian Naomi Horita, Joao Carlos Resende, Jamile Almeida Silva, Guilherme Fialho de Freitas, David Queiroz Muniz, Caio V. Suartz, Leopoldo Alves Ribeiro-Filho, Paulo M. Hoff, José Mauricio Mota

“…Radiographic responses and progression were evaluated by Prostate Cancer Working Group 3. Survival estimates used the Kaplan-Meier method, and correlations were made with Chi-square test for categorical variables.RESULTSFrom January 2011 to January 2023, 341 patients with mCRPC received oral cyclophosphamide at a tertiary cancer center in São Paulo, Brazil. …”
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Incidence of constrained condylar and hinged knee implants and mid- to long-term survivorship: a register-based study from the Nordic Arthroplasty Register Association (NARA) by Jake von Hintze, Ville Ponkilainen, Annette W-Dahl, Nils P Hailer, Ove Furnes, Anne M Fenstad, Mona Badawy, Alma B Pedersen, Martin Lindberg-Larsen, Mika J Niemeläinen, Keijo Mäkelä, Antti Eskelinen

“…Kaplan–Meier (K–M) survival and flexible parametric survival model (FPSM) analyses were performed to estimate revision risk, expressed as hazard ratio (HR) with 95% confidence intervals (CI), with minimally stabilized (MS) TKA acting as the control group (n = 456,137). …”
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Elevated resting heart rate in adolescent men and risk of heart failure and cardiomyopathy by Martin Lindgren, Josefina Robertson, Martin Adiels, Maria Schaufelberger, Maria Åberg, Kjell Torén, Margda Waern, N. David Åberg, Annika Rosengren

“…HF and its concomitant diagnoses, as well as all CM diagnoses, were collected from the national inpatient, outpatient, and cause of death registries. Risk estimates were calculated by Cox‐proportional hazards models while adjusting for potential confounders. …”
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A systematic review and meta-analysis: prevalence and clinical implications of anatomical variants of the hepatic portal vein by Juan José Valenzuela-Fuenzalida, Benjamín Rodríguez-Osorio, Cristian Salgado-Torres, Pablo Nova-Baeza, Mathias Orellana-Donoso, Alejandro Bruna-Mejías, Roberto Avila-Sepulveda, Álvaro Becerra-Farfán, Macarena Rodríguez-Luengo, Juan Sanchis-Gimeno, Guinevere Granite, Héctor Gutiérrez-Espinoza

“…Pooled prevalence was estimated using a random effects model. A total of 31 studies met the established selection criteria. …”
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The economic burden of breast cancer in western Iran: a cross-sectional cost-of-illness study by Banafsheh Darvishi Teli, Meysam Behzadifar, Mania Beiranvand, Aziz Rezapour, Seyed Jafar Ehsanzadeh, Samad Azari, Ahad Bakhtiari, Payam Haghighatfard, Mariano Martini, Maryam Saran, Masoud Behzadifar

“…The total economic burden of breast cancer was estimated at $5,394,409.13, with a mean of $10,275.07 per patient. …”
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Human soft tissue sarcomas harbor an intratumoral viral microbiome which is linked with natural killer cell infiltrate and prognosis by William J Murphy, Robert J Canter, Nikhil Joshi, Sean J Judge, Morgan A Darrow, Steve W Thorpe, Alicia A Gingrich, Lauren M Perry, Sylvia M Cruz, Kara T Kleber, Louis B Jones, Ugur N Basmaci, Matthew L Settles, Blythe P Durbin-Johnson, Arta Monir Monjazeb, Janai Carr-Ascher, Jonathan A Eisen

“…Metagenomic classification was used to estimate abundance using genus and species taxonomic levels across all classified organisms, and data were analyzed with respect to clinicopathologic factors.Results Fifteen patients were enrolled. …”
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Utilisation of alcohol-related treatment after a first alcohol use disorder diagnosis in Hamburg, Germany by Jakob Manthey, Kilian Huß, Sven Buth, Ludwig Kraus, Anna Schranz, Carolin Kilian, Jürgen Gallinat, Ingo Schäfer, Bernd Schulte

“… Abstract Background A variety of treatment options for people with alcohol use disorder (AUD) exist. Surveys estimate that 1 in 10 people with AUD utilise treatment, but real-world treatment pathways remain covert. …”
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Comparison of live birth rate and fetal outcomes between fresh embryo and frozen-thawed embryo transfers: a prospective study by Seyedeh Farinaz Fattahpour, Parvin Hakimi, Fatemeh Tabatabaei, Mahsa Hejazad, Maryam Amoozadeh, Leila Sadeghi, Negin Rezaie, Razih Vejdani, Hosein Azizi

“…Multiple logistic regression analysis was used to estimate adjusted odds ratios (AORs) with 95% confidence intervals (CIs). …”
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Polymorphism of genes associated with infectious lung diseases in Northern Asian populations and in patients with community-acquired pneumonia by S. V. Mikhailova, L. V. Shcherbakova, N. I. Logvinenko, I. I. Logvinenko, M. I. Voevoda

“…The aim of this work was to assess the effect of selection for the genotypes of the above-mentioned SNPs on the gene pools of populations living in harsh climatic conditions that contribute to the development of infectious lung diseases. We estimated the prevalence of these variants in white and Asian (Chukchis and Yakuts) population samples from Northern Asia and among patients with community-acquired pneumonia (CAP). …”
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Situational analysis of the quality of maternal, child, and adolescent health data in the health districts of Thiès, Mbour, Kédougou, and Saraya in Senegal by Fatoumata Binetou Diongue, Adama Faye, Cheikh Loucoubar, Ndèye Marème Sougou, Ibrahima Sy, Adama Tall, Youssoupha Ndiaye, Samba Cor Sarr

“…The following data quality indicators (accuracy, completeness, and promptness) were estimated. An exploratory case study and purposive sampling supported the qualitative part by implementing individual interviews. …”
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Principles of effective out-patient diagnostics of diffuse liver diseases by Komova A. G., M. V. Mayevskaya, V. T. Ivashkin

“…Risk factors for diseases, defined by one-way ANOVA test, were: male gender (p<0,001), excessive body weight and obesity (body mass index >25 kg/m2 (p<0,001)), hyperglycemia (p<0,001), hypertriglyceridemia (p<0,001). By more strict estimation at multifactorial analysis major risk factors were determined: age 30 to 59 years (p<0,001), intake of alcoholic beverages in harmful dozes (over 16 points of AUDIT questionnaire, p=0,04), hypercholesterolemia (p=0,016). …”
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Kidney disease among adults on tenofovir-based second-line antiretroviral therapy in Dar es Salaam, Tanzania by Sabina F. Mugusi, Grace A. Shayo, Philip G. Sasi, Lulu S. Fundikira, Eric A. Aris, Christopher R. Sudfeld, Ferdinand M. Mugusi

“…Socio-demographic and clinical data were gathered, and laboratory tests were conducted to determine the estimated glomerular filtration rate (eGFR). Ultrasonography was performed to visualise the kidneys. …”
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Characterization and Selection of WiFi Channel State Information Features for Human Activity Detection in a Smart Public Transportation System by Roya Alizadeh, Yvon Savaria, Chahe Nerguizian

“…The reported classification results show that using only the chirp rate estimated from CSI information as a feature, we achieve precision &#x003D; 83&#x0025;, True Positive <inline-formula> <tex-math notation="LaTeX">$(TP)=94\%$ </tex-math></inline-formula>, True Negative <inline-formula> <tex-math notation="LaTeX">$(TN)= 91\%$ </tex-math></inline-formula> and F1-score &#x003D; 87&#x0025;. …”
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Identification and verification of autophagy-related gene signatures and their association with immune infiltration and drug responsiveness in epilepsy by Han-han He, Xiao-ge Zhang, Fen-fang Chen

“…The Immune Cell Abundance Identifier (ImmuCellAI) was used to estimate peripheral immune cells abundance of epilepsy. …”
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Prevalence and Determinants of Hypertension Awareness, Treatment, and Control in Botswana: A Nationally Representative Population-Based Survey by Neo M. Tapela, Lei Clifton, Gontse Tshisimogo, Moagi Gaborone, Tebogo Madidimalo, Virginia Letsatsi, Tiny Masupe, Mosepele Mosepele, Joseph Makhema, Shahin Lockman, David J. Hunter

“…We report the first nationally representative estimates of the hypertension care cascade performance in Botswana, which will support planning and future policy evaluations. …”
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Implications of the availability and distribution of birth weight on addressing neonatal mortality: population-based assessment from Bihar state of India by Lalit Dandona, Rakhi Dandona, G Anil Kumar, Debarshi Bhattacharya, Sibin George, Priya Nanda, Md Akbar

“…Assuming proportional correspondence of LBW and NMR in live births with and without birth weight, the estimated LBW among those without birth weight was 35.5% (95% CI 33.0 to 38.0) and among all live births irrespective of birth weight availability was 23.0% (95% CI 21.9 to 24.2). 70% of mothers considered LBW to be a sign of sickness, 59.5% perceived it as a risk of developing other illnesses and 8.6% as having an increased probability of death.Conclusions Missing birth weight is substantially compromising the planning of interventions to address LBW at the population-level. …”
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Contribution à l’analyse de la viabilité d’une petite population de gorilles, Gorilla beringei graueri (Hominidae, Primates), par modélisation et simulations de l’écosystème du Mon... by Jean‑Claude Kasolene Kyungu, Jean Mukulire Malekani, Lohandjola Nyamangombe

“…En exploitant les données de 1996 à 2011 et en les intégrant dans notre modèle, nous avons pu estimer l’ampleur du problème. Nous avons également examiné par PCR, 29 échantillons de matières fécales de gorilles dont 13 pour la détermination de la parenté et 16 pour les pathologies. …”
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