Drying kinetic for moisture content prediction of peels Tahiti lemon (Citrus latifolia): Approach by machine learning and optimization - genetic algorithms and nonlinear programmin... by Maressa O. Camilo, Romero F. Carvalho, Ariany B.S. Costa, Esly F.C. Junior, Andréa O.S. Costa, Robson C. Sousa

“…Heuristic optimization methods, including genetic algorithms (GA) and nonlinear programming (NLP), were employed to identify the best empirical and semi-empirical models for estimating moisture content during the drying process of lemon peel layers. …”
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Treatment preferences of patients with muscle invasive bladder cancer: A discrete choice experiment by Liam Mannion, Verity Watson, Vinod Mullassery, Rajesh Nair, Thomas Charlton, Margaret Northover, Deborah Enting, Mieke Van Hemelrijck, Muhammad Shamim Khan, Ramesh Thurairaja, Suzanne Amery, Kathryn Chatterton, Kate Smith, Simon Hughes

“…The data were analysed using a conditional logit model, and preferences for, and trade‐offs between, attributes were estimated. Results We recruited patients with MIBC who had either already completed, were undergoing or had yet to commence radical treatment for MIBC (n = 60). …”
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Thermal Response and Degressive Reaction Study of Oxo-Biodegradable Plastic Products Exposed to Various Degradation Media by S. M. Al-Salem, A. Y. Al-Nasser, M. H. Behbehani, H. H. Sultan, H. J. Karam, M. H. Al-Wadi, A. T. Al-Dhafeeri, Z. Rasheed, M. Al-Foudaree

“…Analytical kinetic estimation methods relying on model free solutions enabled the determination of the apparent activation energy (Ea) of the specimens postexposure to degradation media. …”
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A phase I, randomized, placebo‐controlled trial to evaluate the pharmacokinetics, safety, and tolerability of nirsevimab in healthy Chinese adults by Xiaomeng Mao, Xiaohan Hua, Chengyi Wu, Xiaoyun Ge, Jie Zhang, Xiaojie Wu, Robert J. Kubiak, Ulrika Wählby Hamrén, Tonya Villafana, Georgios Christou, Jannine Green, Therese Takas, Yuwen Jin

“…Serum nirsevimab concentrations were measured and PK parameters of maximum serum concentration (Cmax), time to maximum concentration (tmax), and area under the concentration‐time curve from time 0 to Day 150 (AUC0–150) were estimated. Treatment emergent adverse events (AEs), clinical laboratory data, and vital signs were evaluated. …”
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Optimization and potential assessment of CO2 geological storage caprock in the saline aquifers of the Qingjiang Basin, middle and lower reaches of the Yangtze River by Yuchen Tian, Shiqi Liu, Sijian Zheng, Shuxun Sang, Yinghai Liu, Shiheng Chen, Helong Zhang, Yanzhi Liu, Yuntian Jiang, Zekun Yue, Wenkai Wang

“…Employing the calculation method proposed by the Carbon Sequestration Leadership Forum (CSLF), the study estimated the CO2 storage capacity in the deep saline aquifers of the Qingjiang Basin. …”
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Evidence mapping and overview of systematic reviews of the effects of acupuncture therapies by Yuqing Zhang, Gordon Guyatt, Lin Wang, Hao Wen, Liming Lu, Gabriel Rada, Lai Wang, Shuqi Ge, Yu Dong, Camila Ávila, Xiaorong Tang, Neng-Gui Xu, Zhao Zeng, Camilo Vergara, Rouhao Chen, Xiaojing Wei, Wen Luo, Jing chun Zeng, Chun-Zhi Tang

“…Seventy-seven SRs represented the effect estimate of acupuncture therapies. Finally, we system summarised the areas of possible underutilisation of acupuncture therapies (high or moderate certainty evidence of large or moderate effects), and the areas of warranting additional investigation of acupuncture therapies (low or very low certainty evidence of moderate or large effects).Conclusion The evidence maps and overview of SRs on acupuncture therapies identified both therapies with substantial benefits that may require more assertive evidence dissemination and promising acupuncture therapies that require further investigation.…”
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Pleiotropic Effects of a KCNQ1 Variant on Lipid Profiles and Type 2 Diabetes: A Family-Based Study in China by Xiaowen Wang, Junhui Wu, Yao Wu, Mengying Wang, Zijing Wang, Tao Wu, Dafang Chen, Xun Tang, Xueying Qin, Yiqun Wu, Yonghua Hu

“…The effect of rs2237895 on T2DM and lipids was estimated using linear regression and logistic regression models after adjustment for multiple covariates. …”
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A deep learning algorithm to generate synthetic computed tomography images for brain treatments from 0.35 T magnetic resonance imaging by Luca Vellini, Flaviovincenzo Quaranta, Sebastiano Menna, Elisa Pilloni, Francesco Catucci, Jacopo Lenkowicz, Claudio Votta, Michele Aquilano, Andrea D’Aviero, Martina Iezzi, Francesco Preziosi, Alessia Re, Althea Boschetti, Danila Piccari, Antonio Piras, Carmela Di Dio, Alessandro Bombini, Gian Carlo Mattiucci, Davide Cusumano

“…Dose distributions using sCT and CT were compared using global gamma analysis at different tolerance criteria (2 %/2mm and 3 %/3mm) and evaluating the difference in estimating different Dose Volume Histogram (DVH) parameters for target and organs at risk (OARs). …”
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High prevalence of overweight/obesity and central obesity among women in a rural district of Nepal in 2012–2013: a population-based study by Chandra Yogal, Chandra Yogal, Astrid Kamilla Stunes, Astrid Kamilla Stunes, Sunila Shakya, Biraj Karmarcharya, Rajendra Koju, Mats P. Mosti, Mats P. Mosti, Miriam K. Gustafsson, Miriam K. Gustafsson, Bjørn Olav Åsvold, Bjørn Olav Åsvold, Berit Schei, Unni Syversen, Unni Syversen

“…BackgroundThe prevalence of overweight is rapidly escalating, especially in South-Asia. We aimed to estimate the prevalence of overweight/obesity and central obesity, and associated risk factors among women in a rural setting of Nepal.MethodsA cross-sectional study addressing reproductive health and non-communicable diseases (NCDs) was conducted 2012–2013 in a rural district of Nepal. …”
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The association between serum ferritin levels and the risk of gestational diabetes mellitus: a prospective cohort study by Shaofei Su, Shen Gao, Enjie Zhang, Jianhui Liu, Shuanghua Xie, Yue Zhang, Ruixia Liu, Wentao Yue, Chenghong Yin

“…Multivariate modified Poisson regression was performed to estimate the independent relationship between serum ferritin levels and the incident GDM. …”
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Helicobacter pylori infection at long-term treatment by proton pump inhibitors for acid-related diseases (Literature review and resolution of Advisory council, March 22, 2018) by V. T. Ivashkin, I. V. Mayev, R. A. Abdulkhakov, O. P. Alekseyeva, S. A. Alekseyenko, A. Yu. Baranovsky, Ye. K. Baranskaya, I. L. Klyaritskaya, N. V. Korochanskaya, Yu. A. Kucheryavy, T. L. Lapina, M. F. Osipenko, V. I. Simanenkov, G. N. Tarasova, A. S. Trukhmanov, I. B. Khlynov, A. A. Sheptulin

“…Testing for H. pylori infection and carrying out the subsequent eradication therapy could allow to prevent progression of corpus mucosa atrophy in patients with acid-related disorders, first of all those with GERD, who received long-term PPI treatment. Estimation of duration of PPI treatment at acid-related disorders, and terms of H. pylori eradication therapy should be evaluated according to clinical guidelines and treatment protocols of these diseases taking into account age of the patient, clinical features, course of disease, presence of complications.…”
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Effect of video-based trauma-informed care training for nursing staff on seclusion and restraint of psychiatric inpatients: A non-randomized controlled study by Michi Miyake, Megumi Hazumi, Kentaro Usuda, Takahiro Kawashima, Maiko Fukasawa, Hisateru Tachimori, Daisuke Nishi

“…The analysis showed that the estimated difference-in-differences coefficient of average restraint time decreased significantly by -0.24 (p = 0.01) at 6 months post-intervention, although seclusion time was not significantly decreased. …”
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Dissecting Causal Relationships Between Antihypertensive Drug, Gut Microbiota, and Type 2 Diabetes Mellitus and Its Complications: A Mendelian Randomization Study by He Zheng, Shiping Wu, Wenbin Wang, Weida Qiu, Yingqing Feng

“…Thus, we conducted a two‐sample Mendelian randomization (MR) analysis to estimate the potential impact of various antihypertensive drug target genes on T2DM and its complications. …”
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Long time-series and high-frequency ecological evaluation of Henan section of the Yellow River by Jianzhong Guo, Daozhu Xu, Jian Xu, Ruoxin Zhu, Ning Li

“…To further elucidate the spatial-temporal distribution pattern, fluctuations, change trends, and future evolution trends of the ecological environment quality, we conducted coefficient of variation fluctuation analysis, Theil-Sen's slope estimation, Mann-Kendall test, and Hurst index calculation. …”
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Identifying the healthy places to live in Australia with a new environmental quality health index by Shuang Zhou, Zhihu Xu, Wenzhong Huang, Yao Wu, Rongbin Xu, Zhengyu Yang, Pei Yu, Wenhua Yu, Tingting Ye, Bo Wen, Shanshan Li, Yuming Guo

“…Exposure-mortality relationships were estimated using a spatial age-period-cohort model, and EQHIs (scored 0–100, with higher values indicating better conditions) were constructed. …”
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Noninvasive prenatal diagnosis (NIPD) of non-syndromic hearing loss (NSHL) for singleton and twin pregnancies in the first trimester by Huanyun Li, Shaojun Li, Zhenhua Zhao, Lingrong Kong, Xinyu Fu, Jingqi Zhu, Jun Feng, Weiqin Tang, Di Wu, Xiangdong Kong

“…Only one family NIPD result is “no call” because the imbalance distribution of SNP sites makes it difficult to estimate recombination events. Most (13/15) of pregnant women were diagnosed in the first trimester and the earliest gestation week was the 7th week. …”
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Causal associations of ambient particulate matter 10 and Alzheimer’s disease: result from a two-sample multivariable Mendelian randomization study by Zehan Huang, Guodong He, Shuo Sun, Yingqing Feng, Yuqing Huang

“…The multivariable MR model adjusted for education. The MR estimates of causality association were expressed as odds ratios (OR) and corresponding 95% confidence intervals (CI). …”
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Measurable residual disease as predictor of post–day +100 relapses after allografting in adult AML by Naveed Ali, Megan Othus, Eduardo Rodríguez-Arbolí, Corentin Orvain, Filippo Milano, Brenda M. Sandmaier, Chris Davis, Ryan S. Basom, Frederick R. Appelbaum, Roland B. Walter

“…Importantly, although 126/136 patients (92%) with MRD before HCT tested negative for MRD at day +70 to +100, their outcomes were inferior to those without MRD before HCT and at day +70 to +100, with 3-year relapse risk of 40% vs 15% (P < .001), 3-year RFS of 50% vs 72% (P < .001), and 3-year OS of 56% vs 76% (P < .001), whereas 3-year nonrelapse mortality estimates were similar (P = .53). Thus, despite high MRD conversion rates, outcomes MRD positive/MRD negative (MRDneg) patients are inferior to those of MRDneg/MRDneg patients, suggesting all patients with pre-HCT MRD should be considered for preemptive therapies after allografting.…”
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Association between lifestyle factors and thyroid function in young sedentary euthyroid adults by Elisa Merchan-Ramirez, Guillermo Sanchez-Delgado, Lucas Jurado-Fasoli, Francisco M Acosta, Manuel Muñoz-Torres, Jose M. Llamas-Elvira, Jonatan R Ruiz

“…Dietary habits were measured by a food frequency questionnaire and three non-consecutive 24 h recalls, and different dietary intake and patterns were then estimated. The time spent in sedentary, PA levels and sleep habits were objectively measured using a wrist-worn accelerometer. …”
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Longitudinal associations of flare and damage accrual in patients with systemic lupus erythematosus by Rangi Kandane-Rathnayake, Sang-Cheol Bae, Zhanguo Li, Shereen Oon, Vera Golder, Mandana Nikpour, Masayoshi Harigai, Zhuoli Zhang, Eric Morand, Chak Sing Lau, Worawit Louthrenoo, Alberta Hoi, Sandra Navarra, Sean O’Neill, Shue-Fen Luo, Yanjie Hao, Yasuhiro Katsumata, Dominique Milea, Aisha Lateef, Laniyati Hamijoyo, Sargunan Sockalingam, Madelynn Chan, Jiacai Cho, Leonid Zamora, Fiona Goldblatt, Yeong-Jian Jan Wu, Xiaomeng Xu, Aldo A Navarro Rojas

“…Objective To estimate the prevalence of organ damage (damage) and flare and to examine longitudinal associations between flares and subsequent damage accrual, in patients with systemic lupus erythematosus (SLE).Methods Patients enrolled in the Asia Pacific Lupus Collaboration cohort with ≥3 years of prospectively captured data were studied. …”
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