Evaluation of the Antioxidant and Cytotoxic Activities on Cancer Cell Line of Extracts of Parasitic Plants Harvested in Tunisia by Imen Ben Attia, Paolo Zucca, Flaminia Cesare Marincola, Mariella Nieddu, Alessandra Piras, Antonella Rosa, Antonio Rescigno, Mohamed Chaieb

“…The antioxidant activity of hexane, ethyl acetate, acetone, methanol, and water extracts obtained by sequential maceration was estimated by DPPH, ABTS and FRAP assays. The metabolic profiles of aqueous extracts were studied by 1 H NMR spectroscopy. …”
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Dynamic changes in peripheral blood lymphocyte trajectory predict the clinical outcomes of sepsis by Dongkai Li, Jiahui Zhang, Wei Cheng, Guoyu Zhao, Xianli Lei, Yawen Xie, Na Cui, Hao Wang

“…A nomogram combining these variables provided individualized risk estimations.ConclusionsThe lymphocyte trajectories delineated novel dynamic phenotypes associated with divergent sepsis outcomes. …”
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Studying the Humoral Response against SARS-CoV-2 in Cuban COVID-19 Recovered Patients by Ivette Orosa Vázquez, Marianniz Díaz, Yaima Zúñiga Rosales, Klayris Amada, Janoi Chang, Ernesto Relova Hernández, Yaima Tundidor, Hilda Roblejo Balbuena, Giselle Monzón, Bárbara Torres Rives, Enrique Noa Romero, Danay Carrillo Valdés, Irinia Valdivia Álvarez, Aurora Delahanty Fernández, Claudia Díaz, Joaquín Solozabal, Mileidys Gil, Belinda Sánchez, Gertrudis Rojas, Beatriz Marcheco, Tania Carmenate

“…Here, we describe the development of an ELISA for the quantification of anti-RBD IgG titers in a large number of samples and a similar test in the presence of NH4SCN as chaotropic agent for estimating the RBD specific antibody avidity. Additionally, a simple and rapid ELISA based on antibody-mediated blockage of the binding RBD-ACE2 was implemented for detecting, as a surrogate of conventional test, the levels of anti-RBD inhibitory antibodies in convalescent sera. …”
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Bidirectional Mendelian Randomization Analysis of the Association Between Mitochondrial Proteins and Neurodegenerative Diseases by Fangyuan Wang, Zhou Jing, Qingyi Wang, Minghe Li, Bingqi Lu, Ao Huo, Chenglin Zhao, Huanyu Zhou, Wulong Liang, Weihua Hu, Xudong Fu

“…The primary method for estimating causal effects was the inverse variance‐weighted (IVW) method, supplemented by additional MR approaches. …”
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Possibility of using a mouse SCID as a model animal to variola virus for evaluating anti-smallpox drug efficacy by K. A. Titova, Al. A. Sergeev, A. S. Kabanov, L. E. Bulychev, Ar. A. Sergeev, D. O. Galahova, A. S. Zamedyanskaya, L. N. Shishkina, O. S. Taranov, V. V. Omigov, E. L. Zavjalov, A. P. Agafonov, A. N. Sergeev

“…At the same time, the 50 % infective dose (ID50) of VARV estimated for animals by registering the presence of the virus in their lungs after 4 days post i.n. infection was 3.5 log10 PFU and was relatively similar to that in humans, theoretically determined by identification of the clinical picture of the disease. …”
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Automatic detection, identification and counting of deep-water snappers on underwater baited video using deep learning by Florian Baletaud, Florian Baletaud, Florian Baletaud, Sébastien Villon, Antoine Gilbert, Jean-Marie Côme, Sylvie Fiat, Corina Iovan, Laurent Vigliola

“…The correlation between automatic and manual estimates of fish MaxN abundance in videos was high (0.72 – 0.9), but the Faster R-CNN showed an underestimation bias at higher abundances. …”
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Increasing exposure of cotton growing areas to compound drought and heat events in a warming climate by Shengli Liu, Wei Zhang, Tongtong Shi, Tong Li, Hui Li, Guanyin Zhou, Zhanbiao Wang, Xiongfeng Ma

“…To address this gap, we analyzed changes in mean temperature and soil moisture within global cotton-growing areas during their respective growing seasons, estimated the probability of CDHEs across multiple spatial scales via copula theorems, and examined the relationship between cotton yield anomalies and CDHEs in major cotton countries. …”
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Spatiotemporal dynamics of soil organic carbon in desert region and its response to climate change: A case study of Heihe river by Yuqing Chen, Haiyang Xi, Wenju Cheng

“…However, the long-term response mechanisms of SOC density in desert regions to climate change remain unclear, increasing uncertainty in estimating the carbon sequestration potential of these ecosystems. …”
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Associations of high-sensitivity C-reactive protein with neuropsychological outcomes and cerebral white matter hyperintensities in older adults at risk of dementia by Rachael Yu, Shawn D. Kong, Catriona Ireland, Genevieve Z. Steiner-Lim, Kimberley Bassett, Hannes Almgren, Dongang Wang, Chenyu Wang, Johannes C. Michaelian, Sharon L. Naismith

“…Structural MRI scans were used to estimate WMH lesion volumes in the whole brain, as well as periventricular, deep white matter, and frontal regions. …”
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Risk factors for Clostridioides difficile infection among patients diagnosed with inflammatory intestinal and rheumatological diseases in the biologic era by Helena Martínez-Lozano, Paula Saralegui-Gonzalez, Elena Reigadas, Pablo Ramón Fueyo-Peláez, Aurea García-García, José Miranda-Bautista, Luis Alcalá, Juan Carlos Nieto, María Elena Lobato-Matilla, Ignacio Marín-Jiménez, Patricia Muñoz, Luis Menchén

“…Risk factors for CDI were assessed using a logistic regression model. We also estimated the incidence rate of CDI for each biologic. …”
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Analysis of the relationship between environmental particulate matter exposure and congenital diseases, as well as the epidemiological trends and burden of impact on newborns by Mulati Julaiti, Dilixiati Wubuli, Tingting Cui, Nadire Nijiati, Pengfei Huang, Bowen Hu

“…Methods: The study employed Mendelian randomization, utilizing single nucleotide polymorphisms as instrumental variables, to estimate the causal effect of environmental Particulate on congenital diseases. …”
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Disparities in surgical treatments for stress, urge and mixed urinary incontinence: Evidence from the 2019 National Ambulatory Surgery Sample (NASS) by Christabel Egemba, Edie Duncan, Katherine Amin, Alan Wein, Alberto J. Caban-Martinez, Raveen Syan

“…Multivariable logistic regression models estimated the associations between socioeconomic factors of receiving the indicated treatment for OAB, SUI, or MUI. …”
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<i>In vitro</i> assay of biological activity of a national preparation of macrophage activating factor (GcMAF-RF) by E. V. Levites, S. S. Kirikovich, E. V. Dolgova, A. S. Proskurina, G. S. Ritter, А. A. Ostanin, E. R. Chernykh, S. S. Bogachev

“…The level of NO production was estimated by the accumulation of nitrogen monoxide in the culture supernatants of peritoneal macrophages by the colorimetric method using the Griess reagent. …”
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Thermal Development, Mortality, and Fertility of an Apulian Strain of <i>Drosophila suzukii</i> at Different Temperatures by Nuray Baser, Luca Rossini, Gianfranco Anfora, Kürşat Mustafa Temel, Stefania Gualano, Emanuele Garone, Franco Santoro

“…The dataset was first analysed according to life tables studies; then, we also estimated the biological parameters of the most common equations describing development, mortality, and fertility involved in physiologically-based model applications. …”
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Blood-based epigenome-wide association study and prediction of alcohol consumption by Elena Bernabeu, Aleksandra D. Chybowska, Jacob K. Kresovich, Matthew Suderman, Daniel L. McCartney, Robert F. Hillary, Janie Corley, Maria Del C. Valdés-Hernández, Susana Muñoz Maniega, Mark E. Bastin, Joanna M. Wardlaw, Zongli Xu, Dale P. Sandler, Archie Campbell, Sarah E. Harris, Andrew M. McIntosh, Jack A. Taylor, Paul Yousefi, Simon R. Cox, Kathryn L. Evans, Matthew R. Robinson, Catalina A. Vallejos, Riccardo E. Marioni

“…Together, these findings show how DNAm can objectively characterize patterns of alcohol consumption that associate with brain health, unlike self-reported estimates.…”
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Integrating hepatitis B care and treatment with existing HIV services is possible: cost of integrated HIV and hepatitis B treatment in a low-resource setting: a cross-sectional hos... by Andrew Kambugu, Philippa Easterbrook, Jacinto Amandua, David Livingstone Ejalu, Joan N Mutyoba, Claude Wandera, Emmanuel Seremba, Alex Muganzi, Racheal Beyagira, Kaggwa Mugagga, Ponsiano Ocama

“…Data were extracted from 3121 files of HIV and hepatitis B virus (HBV) monoinfected patients from the two study sites.Objective To estimate provider costs associated with running an integrated HBV and HIV clinical pathway for patients on lifelong treatment in low-resource setting in Uganda.Outcome measures The annual cost per patient was simulated based on the total amount of resources spent for all the expected number of patient visits to the facility for HBV or HIV care per year.Results Findings showed that Arua hospital had a higher cost per patient in both clinics than did Koboko Hospital. …”
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Serum calprotectin and renal function decline in ANCA-associated vasculitides: a post hoc analysis of MAINRITSAN trial by Xavier Romand, Benjamin Terrier, Athan Baillet, Philippe Gaudin, Loic Guillevin, Christian Pagnoux, Minh Vu Chuong, Marie Hélène Paclet

“…Renal function decline was defined as a 25% decrease in estimated glomerular filtration rate (eGFR) and a change in the eGFR category, or a decrease of 15 mL/min/1.73 m2. …”
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Pan-Cancer Analysis of Disulfidptosis-Related Genes Affecting Prognosis and Tumor Microenvironment by Jingyang SUN, Rongxuan JIANG, Liren HOU, Huanhuan DONG, Yihan LIN, Niuniu DONG, Guangjian ZHANG, Yanpeng ZHANG

“…TME analysis showed that LRPPRC was negatively correlated with immune cells, stromal cells, and estimated scores in all tumor types. TMB analysis revealed the potential research value of DRGs for PD-1/PD-L1 therapy in pan-cancer. …”
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Vehicle Turn Pattern Counting and Short Term Forecasting Using Deep Learning for Urban Traffic Management System by Sundarakrishnan Narayanan, Sohan Varier, Tarun Bhupathi, Manaswini Simhadri Kavali, Mohana, P. Ramakanth Kumar, K. Sreelakshmi

“…Hence, as part of the Bengaluru Mobility Challenge 2024, organized by Bengaluru Traffic Police in collaboration with The Indian Institute of Science, we propose a solution to address the issue by developing a predictive model to estimate vehicle counts by turning pattern from traffic video footage. …”
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Short-term evolution and dispersal patterns of fluconazole-resistance in Candida auris clade III by Irving Cancino-Muñoz, Juan Vicente Mulet-Bayona, Carme Salvador-García, Nuria Tormo-Palop, Remedios Guna, Concepción Gimeno-Cardona, Fernando González-Candelas

“…We have identified three subgroups within clade III, among which two are genetically most closely related. Moreover, we have estimated the evolutionary rate of clade III to be 2.25e-7 s/s/y (2.87 changes per year). …”
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