SPAGRM: effectively controlling for sample relatedness in large-scale genome-wide association studies of longitudinal traits by He Xu, Yuzhuo Ma, Lin-lin Xu, Yin Li, Yufei Liu, Ying Li, Xu-jie Zhou, Wei Zhou, Seunggeun Lee, Peipei Zhang, Weihua Yue, Wenjian Bi

“…SPAGRM can utilize GRM-free models and thus is applicable to various trait types and statistical methods, including linear mixed models and generalized estimation equations for longitudinal traits. A hybrid strategy incorporating saddlepoint approximation greatly increases the accuracy to analyze low-frequency and rare genetic variants, especially in unbalanced phenotypic distributions. …”
Get full text

Localization of Liv2 as an Immature Hepatocyte Marker in EB Outgrowth by Ikkei Takashimizu, Yoshiki Tanaka, Susumu Yoshie, Yoshiya Kano, Hinako Ichikawa, Li Cui, Naoko Ogiwara, Kohei Johkura, Katsunori Sasaki

“…The objective of this study was to establish Liv2, a surface marker of mouse immature hepatocytes (hepatoblasts), as a selection tool for embryonic stem (ES) cell–derived immature hepatocytes by acquiring basic data on Liv2 in normal mouse embryos and by confirming Liv2 expression in mouse ES-derived cells. The estimated molecular weight of Liv2 was 4045 kDa, and immunoreactivity was definitively detected in the cell membrane of fetal hepatocytes on embryonic day (E) 9.5, declined gradually until E12.5, and subsequently became undetectable. …”
Get full text

Resulting Key Physiological Changes in <i>Triticum aestivum</i> L. Plants Under Drought Conditions After Priming the Seeds with Conventional Fertilizer and Greenly Synthesized Zinc... by Roquia Rizk, Mostafa Ahmed, Donia Abdul-Hamid, Mostafa Zedan, Zoltán Tóth, Kincső Decsi

“…Some biochemical compounds, such as total phenolics (TPCs), total flavonoids (TFCs), and total hydrolysable sugars, were estimated as well to show the effect of the different treatments on the wheat plants. …”
Get full text

Vulnerability Assessment for Excessive Acceleration Failure Mode of an Indonesian Ro-Ro Ferry by Model Experiment by Daeng Paroka, Andi Haris Muhammad, Sabaruddin Rahman

“…The roll decay test is used as the alternative method to estimate the non-dimensional logarithmic decrement of roll decay and the damping coefficients to assess the stability base on the excessive acceleration criteria. …”
Get full text

Spi-VSTL: Image data collection platform using off-the shelf hardware for vertically supported crops in state-of-the-art glasshouses by Namal Jayasuriya, Malith Weerasekara, Oula Ghannoum, Yi Guo, Wen Hu

“…The usability of the proposed design has been proved with a published data set and research on plant height estimation. Other use cases and room for further development are also discussed.…”
Get full text

Use of stepwise m5 model tree to forecast the P24max based on teleconnection indices by Golnar Ghanbarzadeh, Khalil Ghorbani, Meysam Salarijazi, Chooghi Bairam Komaki, Laleh Rezaei Ghaleh

“…The normalized root mean square error (NRMSE) of P24max estimation was found to be 15%, 13%, 15%, 8%, 20%, 14%, and 12% with the coefficients of determination of 0.78, 0.79, 0.72, 0.85, 0.81, 0.82, and 0.84 in Hashemabad‐Gorgan, Rasht, Kermanshah, Ahvaz, Bandar Abbas, Isfahan, and Birjand, respectively. …”
Get full text

Effects of Resistance Training and Soy Isoflavone on Body Composition in Postmenopausal Women by Fábio Lera Orsatti, Eliana Aguiar Petri Nahas, Jorge Nahas-Neto, Nailza Maesta, Cláudio Lera Orsatti, Cesar Edurado Fernandes

“…At baseline and 9-months, fat and muscle mass were estimated by DXA. ANOVA and test t were used. Results. …”
Get full text

Arterial Stiffness Is More Associated with Albuminuria than Decreased Glomerular Filtration Rate in Patients with Type 2 Diabetes Mellitus: The REBOUND Study by Jong Ho Kim, Sang Soo Kim, In Joo Kim, Bo Hyun Kim, Ja Young Park, Chang Won Lee, Ji Hye Suk, Sun Hae Shin, Sung Pyo Son, Min Chul Kim, Jun Hyeob Ahn, Kwang Jae Lee, Min Jung Kwon, Soon Hee Lee, Jeong Hyun Park

“…Additionally, the patients were categorized into four groups according to their albumin-to-creatinine ratio (ACR, normoalbuminuria versus albuminuria) and estimated GFR (eGFR, <60 mL/min/1.73 m2 versus ≥60 mL/min/1.73 m2). …”
Get full text

Mapping dynamic regulation of gene expression using single-cell transcriptomics and application to complex disease genetics by Hanna Abe, Phillip Lin, Dan Zhou, Douglas M. Ruderfer, Eric R. Gamazon

“…The resulting framework quantifies the dynamics of the genetic regulation of gene expression and estimates its cell-type specificity. As an application, we show that the approach detects known and new genes associated with schizophrenia and enables insights into context-dependent disease mechanisms. …”
Get full text

Donor Identification, Genetic Diversity, Population Structure and Marker–Trait Association Analyses for Iron Toxicity Tolerance Using Rice Landraces by Debanjana Saha, Udit Nandan Mishra, Chittaranjan Sahoo, Seema Tripathy, Uttam Kumar Behera, Susmita Das, Chandrasekhar Sahu, Shiv Datt, Manoj Kumar Rout, Tanmaya Lalitendu Mohanty, Shakti Prakash Mohanty, Saumya Ranjan Barik, Ishwar Chandra Mohanty, Sharat Kumar Pradhan

“…The studied population showed a moderate to high degree of genetic diversity, as revealed by the estimated molecular diversity parameters and principal component, cluster and box plot analyses. …”
Get full text

A Centralized Multi-Agent DRL-Based Trajectory Control Strategy for Unmanned Aerial Vehicle-Enabled Wireless Communications by Getaneh Berie Tarekegn, Rong-Terng Juang, Belayneh Abebe Tesfaw, Hsin-Piao Lin, Huan-Chia Hsu, Robel Berie Tarekegn, Li-Chia Tai

“…Initially, we developed a long short-term memory-based link quality estimation model to assess each user&#x0027;s link quality over time. …”
Get full text

The food environment in favelas is associated with the presence of arterial hypertension and diabetes in socially vulnerable women by Luiz Gonzaga Ribeiro Silva-Neto, Risia Cristina Egito de Menezes, Juliana Souza Oliveira, Nathalia Paula de Souza, Thays Lane Ferreira dos Santos, Telma Maria de Menezes Toledo Florêncio

“…Logistic regression models were applied using generalized estimating equations, adjusted for age, education, race/skin color, and poverty status. …”
Get full text

Uptake kinetics and distribution of flupyrimin by rice (Oryza sativa L.): Effects of subcellular fractionation and soil factors by Xugen Shi, Min Wang, Zhenyu Jiang, Ruqiang Cui, Baotong Li, Xianpeng Zhang, Lianhu Zhang, Duantao Cao

“…Interestingly, the concentration of flupyrimin in rice was significantly positively correlated with its amount in the soil pore water (CIPW) (R2 > 0.967, P < 0.003), indicating that the uptake and accumulation of flupyrimin in rice planting systems can be estimated by CIPW. These findings enhance our knowledge of flupyrimin absorption and distribution in rice plants from treated soils and are important for guiding its field application and conducting environmental risk assessments.…”
Get full text

Experimental Verification of the Field Robotic System for Pipeline Maintenance by Thanh Phuong Nguyen, Hung Nguyen, Nhat Minh Ngo, Ha Quang Thinh Ngo

“…Owing to the size of tube and the curved trajectory, the estimated parameters and shape of robot could be known. …”
Get full text

Origin and post-harvest losses of vegetables in the microregion of Chapadinha, Maranhão, Brazil by Tiago Fernando Riew Tomm, Edmilson Igor Bernardo Almeida, Kessia Tenório Figueirinha, Lusiane de Sousa Ferreira, Márcia Maria de Souza Gondim, Deucleiton Jardim Amorim

“…Research involving estimation of post-harvest losses of vegetables is limited in the state of Maranhão (MA), however, they are essential to identify of causes of losses, as well as for reducing them. …”
Get full text

Effects of Prognostic Nutrition Index, Neutrophil/Lymphocyte Ratio, and C-reactive Protein/Albumin Ratio on Prognosis Undergoing Open Heart Surgery by Anil Kilinc, Nilay Tas, Melih Urkmez, Ebru Canakci, Ilker Coskun, Merve Elif Demirhan

“…Conclusion: PNI, a marker of inflammatory and immune processes, may be a beneficial variable for estimating postoperative prognosis among patients undergoing open heart surgery.…”
Get full text

Occurrence of Aflatoxin M₁ in Raw and Processed Milk: A Contribution to Human Exposure Assessment After 12 Years of Investigation by Simona Summa, Sonia Lo Magro, Valeria Vita, Cinzia Franchino, Valentina Scopece, Pasqualino D’Antini, Marco Iammarino, Rita De Pace, Marilena Muscarella

“…The aim of this study was to estimate the aflatoxin M₁ (AFM₁) contamination in raw milk and processed milk (pasteurized or UHT) collected from two regions in Italy (Puglia and Basilicata) during a 12-year period: 2012–2023. …”
Get full text

ALMA Observations of Massive Clouds in the Central Molecular Zone: External-pressure-confined Dense Cores and Salpeter-like Core Mass Functions by Zhenying Zhang, Xing Lu, Tie Liu, Sheng-Li Qin, Adam Ginsburg, Yu Cheng, Hauyu Baobab Liu, Daniel L. Walker, Xindi Tang, Shanghuo Li, Qizhou Zhang, Thushara Pillai, Jens Kauffmann, Cara Battersby, Siyi Feng, Suinan Zhang, Qi-Lao Gu, Fengwei Xu, Wenyu Jiao, Xunchuan Liu, Li Chen, Qiu-yi Luo, Xiaofeng Mai, Zi-yang Li, Dongting Yang, Xianjin Shen, Meizhu Liu, Zhiqiang Shen

“…With our new temperature estimates we also find that the CMFs show a Salpeter-like slope in the high-mass (≳3–6 M _⊙ ) end, a change from previous works. …”
Get full text

Research on Slope Stability Evaluation Based on Improved Set Pair Analysis Method: A Case of Tonglvshan Open-Pit Mine by Xiaojie Yang, Zhenli Hao, Gaotong Ma, Gan Li

“…Second, the objective weight and subjective weight of each evaluation index are calculated by entropy and fuzzy analytic hierarchy process, and then the comprehensive weight of the evaluation index is estimated based on subjective weight and objective weight. …”
Get full text

Predictive Value of Novel Inflammation-Based Biomarkers for Pulmonary Hypertension in the Acute Exacerbation of Chronic Obstructive Pulmonary Disease by Huanhuan Zuo, Xiaochen Xie, Jiahuan Peng, Lixin Wang, Rong Zhu

“…The blood biomarker levels were positively correlated with NT-proBNP levels, while they had no significant correlation with the estimated pulmonary arterial systolic pressure (PASP) other than PLR. …”
Get full text