Oleuropein Improves Cognitive Dysfunction and Neuroinflammation in Diabetic Rats through the PI3K/Akt/mTOR Pathway by Jianru Shang, Shan Che, Mingjie Zhu

“…After the last treatment, the Morris water maze experiment was carried out, and the rats were first subjected to training experiments for 4 consecutive days; the escape latency, number of crossing platform quadrant intersections, time spent in the target quadrant, and swimming speed were recorded. …”
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Progression of the surge in the Negribreen Glacier System from two years of ICESat-2 measurements by Thomas Trantow, Ute Christina Herzfeld

“…Detailed and precise mapping of height changes on surging glaciers has previously escaped observations from space due to the limited resolution of space-borne altimeter data and the surface characteristics of glaciers during surge, such as heavy crevassing. …”
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Des liaisons dangereuses ? Réseaux hérités, supposés et déguisés d’une nonne vénitienne au XVIIe siècle by Francesca Medioli

“…The analysis focusses on the ways Argangela Tarabotti activated these different relations, thus establishing her own networks, which enabled her to escape partially her condition as a nun and to have access, through correspondence and print, to the male universe of letters where she found intellectual recognition.…”
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Applying a quantitative fire risk assessment method in hospital settings: Case study. by Marzieh Beljikangarlou, Ali Ghazvinloo, Alireza Dehdashti, Mohammad Reza MirLavasani

“…The study emphasizes the importance of implementing targeted fire safety measures, especially regarding oxygen-supplying equipment, high-density ventilators, and limited escape routes, to mitigate risks effectively in healthcare settings. …”
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Effect of Electroacupuncture at Changqiang Acupoint on Learning and Memory Ability and Hippocampal CA1 Apoptosis in Rats with Vascular Dementia by Ke'ai CHEN, Ping YU, Jie CHEN, Lianhong HUANG, Wei XU

“…After the treatment, the water maze test and the TUNEL test were examined.Results:Compared with the model group, the escape latent period and the CA1 apoptosis of the blank control group and the EA treatment group were apparently shorter (<italic>P</italic>&lt;0.05), and the times of crossing the platform were significantly increased (<italic>P</italic>&lt;0.05). …”
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Evolution of power as an indicator of structural transformations: political and managerial aspect by V. V. Tyan

“…Soviet rule, effective in mobilizing society, with real achievements, did not escape a critical number of negative indexes. Almost one hundred percent legitimization of the Soviet government did not remove doubts about its strength. …”
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Consequence Modelling and Analysis of Methane Explosions: A prelimi-nary Study on Biogas Stations by Pelin Güzel, Emine Can, Müge Ensari Özay

“…By using ALOHA software, two different scenarios as leakage from the biogas tank and flammable chemical escaping directly into the atmosphere are designed and calculated by the Gaussian model. …”
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Do they understand more? Turkish EFL speakers perception of sentence stress in English by Anita Buczek-Zawiła

“…As such, either alone or in combination, it may communicate certain additional shades of meaning that, similarly to the contribution of sentence intonation, may escape the attention of EFL speakers. The paper explores the comprehension sensitivity of Turkish speakers of English when it comes to identifying meaning details contributed by sentence stress. …”
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A novel feature extraction method based on dynamic handwriting for Parkinson's disease detection. by Huimin Lu, Guolian Qi, Dalong Wu, Chenglin Lin, Songzhe Ma, Yingqi Shi, Han Xue

“…Finally, we proposed an escape Coati Optimization Algorithm (eCOA) for global optimization to enhance classification performance. …”
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Machine learning with knowledge constraints for design optimization of microring resonators as a quantum light source by Parisa Sadeghli Dizaji, Hamidreza Habibiyan

“…Our model, after only 5 optimization rounds, identified two optimal structures with distinct cross-sectional areas and radii (65 $$\:\mu\:m$$ and 110 $$\:\mu\:m$$ ), achieving escape efficiencies over 90% and on-chip squeezing levels of 7.48 dB and 9.86 dB, respectively. …”
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Disrupting EDEM3‐induced M2‐like macrophage trafficking by glucose restriction overcomes resistance to PD‐1/PD‐L1 blockade by Shaoyong Peng, Minshan Wu, Qian Yan, Gaopo Xu, Yumo Xie, Guannan Tang, Jinxin Lin, Zixu Yuan, Xiaoxia Liang, Ze Yuan, Jingrong Weng, Liangliang Bai, Xiaolin Wang, Huichuan Yu, Meijin Huang, Yanxin Luo, Xiaoxia Liu

“…Cancer‐associatedfibroblasts (CAFs) are significant in immune escape and resistance toimmunotherapy, emphasizing the urgent need for new treatment strategies. …”
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Effects of Exercise Preconditioning Mediating Oxidative Stress to Regulate PI3K/Akt and Nrf2/HO-1 Pathways to Alleviate Cognitive and Learning Disorders in Rats by KONG Haijun, LI Xinlong, WANG Fenghua, CHEN Xiaoan

“…The relative expression levels of Nox1, Duox2, GCLM and PI3K/Akt and Nrf2/HO-1 pathway proteins in hippocampus were detected by Western blot.ResultsCompared with the control group and the exercise group, the 3 d escape latency of the exposed group increased (<italic>P</italic>&lt;0.05). …”
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Correlation of the Changes of Gray Matter Volume with Aβ Deposition and Learning and Memory Abilities in APP/PS1 Mice at Different Periods by Yuhao ZHANG, Hao JIN, Xiufeng ZHANG, Shengxiang LIANG, Weilin LIU, Jing TAO, Lidian CHEN

“…The brain paraffin sections of two groups of mice of different months were separated and prepared, and the Aβ deposition in bilateral entorhinal cortex and hippocampus of the two groups was detected by Thioflavine-s fluorescence staining, and the correlation between the changes of gray matter volume and memory learning ability and Aβ deposition in the corresponding brain area of the two groups was analyzed by Pearson correlation analysis.Results:①The results of Morris water maze test: compared with the WT group, there was no significant difference in the behavioral results of the 2-month-old mice in the APP/PS1 group, and the difference was not statistically significant (<italic>P</italic>&gt;0.05); the escape latency of mice of the APP/PS1 group at the 6 and 12 month-old increased significantly, the number of crossing platforms of the APP/PS1 group at the 6 and 12 month-old decreased significantly, and the difference was statistically significant (<italic>P</italic>&lt;0.05).②The results of MRI T2WI scan: compared with the WT group, there was no significant change in the gray matter volume of the APP/PS1 group at 2-month-old, and the difference was not statistically significant (<italic>P</italic>&gt;0.05); the volume of the entorhinal cortex of the APP/PS1 group at 6-month-old decreased significantly, and the volume of the entorhinal cortex and hippocampus of the APP/PS1 group at 12-month-old mice decreased significantly, the difference was statistically significant (<italic>P</italic>&lt;0.05).③The results of Th-s fluorescence staining test: Aβ deposition was not detected in WT group and APP/PS1 group at 2-month-old; compared with the WT group, a small amount of Aβ deposition could be detected in the entorhinal cortex and hippocampus of the APP/PS1 group at 6-month-old, while a large number of dense Aβ plaques can be detected in the entorhinal cortex and hippocampus of the APP/PS1 group at 12-month-old.④Correlation analysis results: APP/PS1 group mice's entorhinal cortex and hippocampus volume changes were significantly negatively correlated with escape latency (<italic>r</italic>=-0.729, <italic>P</italic>&lt;0.001; <italic>r</italic>=-0.643, <italic>P</italic>&lt;0.001); the volume changes of the entorhinal cortex and hippocampus in the APP/PS1 group showed a positive correlation with the number of crossing platforms (<italic>r</italic>=0.705, <italic>P</italic>&lt;0.001; <italic>r</italic>=0.719, <italic>P</italic>&lt;0.001); the volume changes of the entorhinal cortex and hippocampus in the APP/PS1 group were significantly negatively correlated with Aβ deposition (<italic>r</italic>=-0.865, <italic>P</italic>&lt;0.001; <italic>r</italic>=-0.885, <italic>P</italic>&lt;0.001).Conclusion:APP/PS1 transgenic mice may have learning and memory dysfunction at 6-month-old, and it gradually worsen with time; the learning and memory dysfunction may be related to the atrophy of the entorhinal cortex and hippocampus in the brain of mice, and excessive Aβ deposition may be the one of the factors that cause the brain gray matter volume to shrink.…”
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Therapy-induced senescent cancer cells contribute to cancer progression by promoting ribophorin 1-dependent PD-L1 upregulation by Hyun Jung Hwang, Donghee Kang, Jisoo Shin, Jonghun Jung, Soyeon Ko, Kyung Hee Jung, Soon-Sun Hong, Ji Eun Park, Myung Jin Oh, Hyun Joo An, Wen-Hao Yang, Young-Gyu Ko, Jong-Ho Cha, Jae-Seon Lee

“…These results provide crucial insights into how senescent cancer cells can escape T-cell immunity following cancer treatment and thereby contribute to cancer recurrence. …”
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A ‘torn bag mechanism’ of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes) by Tamás Visnovitz, Dorina Lenzinger, Anna Koncz, Péter M Vizi, Tünde Bárkai, Krisztina V Vukman, Alicia Galinsoga, Krisztina Németh, Kelsey Fletcher, Zsolt I Komlósi, Csaba Cserép, Ádám Dénes, Péter Lőrincz, Gábor Valcz, Edit I Buzas

“…We also demonstrated that upon spontaneous rupture of the limiting membrane of the MV-lEVs, their intraluminal vesicles (ILVs) escaped to the extracellular environment by a ‘torn bag mechanism’. …”
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The Vertebral Column, Ribs, and Sternum of the African Giant Rat (Cricetomys gambianus Waterhouse) by Matthew Ayokunle Olude, Oluwaseun Ahmed Mustapha, Temitope Kehinde Ogunbunmi, James Olukayode Olopade

“…The vertebral column is adapted for strong muscular attachment and actions helping the rodent suited for speed, agility, dexterity, and strength which might enable it to overpower prey and escape predation.…”
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A filter inspired by deep-sea glass sponges for oil cleanup under turbulent flow by Yuan Yu, Chi Ding, Jinna Zhang, Nanqi Ren, Chuyang Y. Tang, Shijie You

“…Technical challenges remain for conventional static adsorption due to hydrodynamic instability under complex water-flow conditions, which results in low oil-capture efficiency, time delay and oil escape. To address this issue, we design a vortex-anchored filter inspired by the anatomy of deep-sea glass sponges (E. aspergillum) by mimicking their exceptional skeletal features and filter-feeding patterns. …”
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Precise intracellular uptake and endosomal release of diverse functional mRNA payloads via glutathione-responsive nanogels by Rupali Dabas, Naveenan Navaratnam, Haruki Iino, Saidbakhrom Saidjalolov, Stefan Matile, David Carling, David S. Rueda, Nazila Kamaly

“…Notably, mechanistic cellular uptake studies revealed that disulphide-containing NGs exhibit enhanced cellular uptake and endosomal escape, potentially due to interactions with cell surface thiols. …”
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A single residue switch mediates the broad neutralization of Rotaviruses by Yang Huang, Feibo Song, Yuanjun Zeng, Hui Sun, Roufang Sheng, Xuechun Wang, Liqin Liu, Guoxing Luo, Yanan Jiang, Yaling Chen, Mengxuan Zhang, Shiyin Zhang, Ying Gu, Hai Yu, Shaowei Li, Tingdong Li, Qingbing Zheng, Shengxiang Ge, Jun Zhang, Ningshao Xia

“…Abstract Broadly neutralizing antibodies (bNAbs) could offer escape-tolerant and lasting protection against viral infections and therefore guide development of broad-spectrum vaccines. …”
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Self-Assembling Multifunctional Peptide Dimers for Gene Delivery Systems by Kitae Ryu, Gyeong Jin Lee, Ji-yeong Choi, Taewan Kim, Tae-il Kim

“…Bafilomycin A1-treated transfection results suggest that the transfection of MPD is mediated via endosomal escape by endosome buffering ability. These results show the potential of MPD for MMP-2 targeted gene delivery systems due to its multifunctionality.…”
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