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Precise and interpretable neural networks reveal epigenetic signatures of aging across youth in health and disease
Published 2025-01-01Subjects: Get full text
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Mir-449b improves the epigenetic status of buffalo transgenic embryos produced by handmade cloning
Published 2023-11-01Subjects: Get full text
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123
Epigenetic Drug Interventions in Breast Cancer: A Narrative Review of Current Research and Future Directions
Published 2024-09-01“…While there is strong evidence that epigenetic alterations, consisting of changes in DNA methylation, histone modifications, and non-coding RNAs, play a crucial role in breast cancer initiation and development, additional research is warranted to elucidate the safety profile of long-term interventions involving epigenetic drugs and to validate the role of epigenetic markers in disease diagnosis, prognosis, and personalised treatment. …”
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Opposite roles of serotonin and neuropeptide FMRFamide in the regulation of epigenetic processes involved in the longterm memory formation
Published 2016-05-01Subjects: “…epigenetics…”
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125
Transcriptomic reprogramming and epigenetic regulation underlying pollination-dependent and auxin-induced fruit set in tomato
Published 2025-02-01Subjects: Get full text
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126
Epigenetic regulation of the nuclear genome associated with mitochondrial dysfunction in Leber’s hereditary optic neuropathy (LHON)
Published 2024-01-01“…Therefore, here, we studied the epigenetic alterations of NDUFS4 by focusing on histone activation and repressive markers. …”
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127
Mono-allelic epigenetic regulation of polycistronic transcription initiation by RNA polymerase II in Trypanosoma brucei
Published 2025-02-01“…Our findings support epigenetic regulation of Pol II transcription initiation as a viable mechanism of gene expression control in T. brucei. …”
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Sequential Release HydroLipo System for STING Gene Epigenetic Reprogramming and Immune Activation in Glioblastoma
Published 2025-02-01Subjects: “…epigenetic reprogramming…”
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129
Epigenetic «probes» for lung cancer monitoring: LINE-1 methylation pattern in blood- circulating DNA
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Curcumin Prevents Free Fatty Acid-Induced Lipid Accumulation via Targeting the miR-22-3p/ CRLS1 Pathway in HepG2 Cells
Published 2024-02-01Subjects: Get full text
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Epigenetic suppression of creatine kinase B in adipocytes links endoplasmic reticulum stress to obesity-associated inflammation
Published 2025-02-01“…Through follow-up studies, we found that ER stress through the IRE1–XBP1s pathway, promotes CKB promoter methylation via the methyltransferase DNMT3A. This epigenetic change represses CKB transcription, shifting metabolism towards glycolysis and increasing the production of the pro-inflammatory chemokine CCL2. …”
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Housing insecurity pathways to physiological and epigenetic manifestations of health among aging adults: a conceptual model
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134
Epigenetic age acceleration and methylation differences in IgG4-related cholangitis and primary sclerosing cholangitis
Published 2025-01-01Subjects: Get full text
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Epigenetic Changes in Endothelial Progenitors as a Possible Cellular Basis for Glycemic Memory in Diabetic Vascular Complications
Published 2015-01-01“…Furthermore, various epigenetic marks have been proposed to closely associate with vascular glycemic memory. …”
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137
A Review of Three Different Studies on Hidden Markov Models for Epigenetic Problems: A Computational Perspective
Published 2014-12-01“…Here, we review three HMM-based studies that have contributed to epigenetic research, from a computational perspective. …”
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Inhibition of Mitochondrial Fission Reverses Simulated Microgravity-Induced Osteoblast Dysfunction by Enhancing Mechanotransduction and Epigenetic Modification
Published 2025-01-01“…Moreover, our study showed that SMG-induced chromatin remodeling and histone methylation, which are epigenetic barriers to osteogenic differentiation, can be reversed by targeting mitochondrial fission, further highlighting the significance of mitochondrial dynamics in osteoblast function in an SMG environment. …”
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Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets
Published 2025-02-01Subjects: Get full text
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Assessment of relationships between epigenetic age acceleration and multiple sclerosis: a bidirectional mendelian randomization study
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