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Housing insecurity pathways to physiological and epigenetic manifestations of health among aging adults: a conceptual model
Published 2025-01-01Subjects: Get full text
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Epigenetic age acceleration and methylation differences in IgG4-related cholangitis and primary sclerosing cholangitis
Published 2025-01-01Subjects: Get full text
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Epigenetic Changes in Endothelial Progenitors as a Possible Cellular Basis for Glycemic Memory in Diabetic Vascular Complications
Published 2015-01-01“…Furthermore, various epigenetic marks have been proposed to closely associate with vascular glycemic memory. …”
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A Review of Three Different Studies on Hidden Markov Models for Epigenetic Problems: A Computational Perspective
Published 2014-12-01“…Here, we review three HMM-based studies that have contributed to epigenetic research, from a computational perspective. …”
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Inhibition of Mitochondrial Fission Reverses Simulated Microgravity-Induced Osteoblast Dysfunction by Enhancing Mechanotransduction and Epigenetic Modification
Published 2025-01-01“…Moreover, our study showed that SMG-induced chromatin remodeling and histone methylation, which are epigenetic barriers to osteogenic differentiation, can be reversed by targeting mitochondrial fission, further highlighting the significance of mitochondrial dynamics in osteoblast function in an SMG environment. …”
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Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets
Published 2025-02-01Subjects: Get full text
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Nucleolar PARP-1 Expression Is Decreased in Alzheimer’s Disease: Consequences for Epigenetic Regulation of rDNA and Cognition
Published 2016-01-01“…PARP-1 has been identified as an epigenetic regulator of plasticity and memory. Thus, we hypothesize that PARP-1 may be altered in postmortem hippocampus of individuals with AD compared to age-matched controls without neurologic disease. …”
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Development of nucleus-targeted histone-tail-based photoaffinity probes to profile the epigenetic interactome in native cells
Published 2025-01-01“…Abstract Dissection of the physiological interactomes of histone post-translational modifications (hPTMs) is crucial for understanding epigenetic regulatory pathways. Peptide- or protein-based histone photoaffinity tools expanded the ability to probe the epigenetic interactome, but in situ profiling in native cells remains challenging. …”
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12,13-diHOME Promotes Inflammatory Macrophages and Epigenetically Modifies Their Capacity to Respond to Microbes and Allergens
Published 2024-01-01“…We hypothesized that macrophages, which are key to both antimicrobial and antigen responses, are functionally and epigenetically modified by 12,13-diHOME leading to short- and long-term dysfunction with consequences for both antimicrobial and antigenic responses. …”
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Epigenetic alterations of 11beta-hydroxysteroid dehydrogenase 1 gene in the adipose tissue of patients with primary aldosteronism
Published 2024-03-01Subjects: Get full text
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Knockout of the ING5 epigenetic regulator confirms roles in stem cell maintenance and tumor suppression in vivo.
Published 2025-01-01“…INhibitor of Growth (ING1-5) proteins are epigenetic readers that target histone acetyltransferase (HAT) or histone deacetylase (HDAC) complexes to the H3K4Me3 mark of active transcription. …”
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N6-Methyladenosine in RNA and DNA: An Epitranscriptomic and Epigenetic Player Implicated in Determination of Stem Cell Fate
Published 2018-01-01“…N6-Methyladenosine modification in DNA (m6dA), mRNA (m6A), tRNA, and other noncoding RNAs has been defined as another important epigenetic and epitranscriptomic marker in eukaryotes in recent years. …”
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ROLE OF THE MODULATORY MEDIATOR SEROTONIN IN THE INDUCTION OF EPIGENETIC PROCESSES DURING LONG TERM MEMORY FORMATION IN HELIX
Published 2015-01-01Subjects: “…epigenetics…”
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The role of genetic diversity, epigenetic regulation, and sex-based differences in HIV cure research: a comprehensive review
Published 2025-01-01Subjects: Get full text
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Exosomes and microRNAs as mediators of the exercise
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