Sex and gender differences in the molecular etiology of Parkinson’s disease: considerations for study design and data analysis by Samantha L. Schaffner, Kira N. Tosefsky, Amy M. Inskter, Silke Appel-Cresswell, Julia M. Schulze-Hentrich

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Hepatic Cholesterol-25-Hydroxylase Overexpression Improves Systemic Insulin Sensitivity in Mice by Britta Noebauer, Alexander Jais, Jelena Todoric, Klaus Gossens, Hedwig Sutterlüty-Fall, Elisa Einwallner

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Pan-Cancer Analysis of B4GALNT1 as a Potential Prognostic and Immunological Biomarker by Hang Yi, Yiwen Lin, Yutong Li, Yeqi Guo, Ligong Yuan, Yousheng Mao

“…Methods including correlation analysis, Cox regression analysis, and Kaplan-Meier analysis were used to explore the expression pattern, prognosis, tumor infiltration pattern, genetics and epigenetics, and drug sensitivity of B4GALNT1 in pan-cancer patients from the above datasets. …”
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Osteoblast-Specific Overexpression of Nucleolar Protein NO66/RIOX1 in Mouse Embryos Leads to Osteoporosis in Adult Mice by Qin Chen, Krishna M. Sinha, Benoit de Crombrugghe, Ralf Krahe

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A cross-sectional survey benchmarking the coverage and importance of obesity-related competencies in U.S. dietetic supervised practice programs by Rosanna P. Watowicz, Varsha Krishnan, W. Scott Butsch

“…Very few programs reported ‘not at all incorporated’ for any competencies; the most frequent were ‘potential role of genetics/epigenetics’ (15%, n = 5) and ‘physiology/pathophysiology of obesity’ (12%, n = 4). …”
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Neoantigen mRNA vaccines and A2A receptor antagonism: A strategy to enhance T cell immunity by Saber Imani, Parham Jabbarzadeh Kaboli, Ali Babaeizad, Mazaher Maghsoudloo

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Sirtuin1 Targeting Reverses Innate and Adaptive Immune Tolerance in Septic Mice by Ayana N. Martin, Martha Alexander-Miller, Barbara K. Yoza, Vidula Vachharajani, Charles E. McCall

“…NAD+-sensing nuclear sirtuin1 (SIRT1) epigenetically guards immune and metabolic homeostasis during sepsis. …”
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TOP2A inhibition and its cellular effects related to cell cycle checkpoint adaptation pathway by Maria C. Arroyo López, M. A. Fernández-Mimbrera, E. Gollini, A. Esteve-Codina, A. Sánchez, Juan Alberto Marchal Ortega

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Expanded taxonomies of human memory by Jason R. Finley

“…The second expansion encompasses numerous biological systems beside the brain, including the immune system, genetics (DNA and epigenetics), and traces of the past stored elsewhere in the body (skin, hair, body modification, nails, bones and teeth, muscles and movement, voice, digestion and excretion, blood, reproductive systems, fat, lungs, and body-based numerical representation). …”
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Quantitative trait loci for grain mineral element accumulation in Vietnamese rice landraces. by Hien Linh Tran, Giang Thi Hoang, Nhung Thi Phuong Phung, Ham Huy Le, Alexandre Grondin, Pascal Gantet

“…LOC_Os05g04330, present in qRP5-1 and associated with phosphorus content in brown rice, encodes a CHH methylation maintenance protein, and its expression is downregulated in roots in the presence of the phosphorus uptake 1 (Pup1), suggesting a role for epigenetics in the regulation of phosphorus uptake and accumulation in grain. …”
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Novel Pathogenic Variant in TGFBR2 Confirmed by Molecular Modeling Is a Rare Cause of Loeys-Dietz Syndrome by Michael T. Zimmermann, Raul A. Urrutia, Patrick R. Blackburn, Margot A. Cousin, Nicole J. Boczek, Eric W. Klee, Colleen Macmurdo, Paldeep S. Atwal

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miR-449a/miR-340 reprogram cell identity and metabolism in fusion-negative rhabdomyosarcoma by Enrico Pozzo, Laura Yedigaryan, Nefele Giarratana, Chao-chi Wang, Gabriel Miró Garrido, Ewoud Degreef, Vittoria Marini, Gianmarco Rinaldi, Bernard K. van der Veer, Gabriele Sassi, Guy Eelen, Mélanie Planque, Alessandro Fanzani, Kian Peng Koh, Peter Carmeliet, Jason T. Yustein, Sarah-Maria Fendt, Anne Uyttebroeck, Maurilio Sampaolesi

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Artemisia capillaris with two novel active compounds, Kawarayomogin I and II, inhibits HYBID (KIAA1199) expression as well as hyaluronic acid degradation by Kazal Boron Biswas, Yuka Kawai, Satoshi Nakagawa, Kyoko Kanai, Hiroyuki Kojima, Teruaki Masutani, Masayoshi Oyama, Arunasiri Iddamalgoda, Kotaro Sakamoto

“…Subsequent mechanism elucidation studies showed that ACFE epigenetically regulates the expression of HYBID by modulating the expression of a specific miRNA, miR-486-5p, which is known to directly target and inhibit HYBID expression. …”
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Hypoxia-induced CTCF mediates alternative splicing via coupling chromatin looping and RNA Pol II pause to promote EMT in breast cancer by Parik Kakani, Shruti Ganesh Dhamdhere, Deepak Pant, Rushikesh Joshi, Sachin Mishra, Anchala Pandey, Dimple Notani, Sanjeev Shukla

“…Summary: Hypoxia influences the epithelial-mesenchymal transition (EMT) through the remodeling of the chromatin structure, epigenetics, and alternative splicing. Hypoxia drives CCCTC-binding factor (CTCF) induction through hypoxia-inducible factor 1-alpha (HIF1α), which promotes EMT, although the underlying mechanisms remain unclear. …”
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Changes in RNA Splicing: A New Paradigm of Transcriptional Responses to Probiotic Action in the Mammalian Brain by Xiaojie Yue, Lei Zhu, Zhigang Zhang

“…Most studies have primarily investigated how gut bacteria modulate host epigenetics and gene expression; their impact on host alternative splicing, particularly in the brain, remains largely unexplored. …”
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The importance of fungi and of mycology for a global development of the bioeconomy by L. Lange, L. Bech, P.K. Busk, M.N. Grell, Y. Huang, M. Lange, T. Linde, B. Pilgaard, D. Roth, X. Tong

“…This knowledge can be obtained by studying the fungal proteome and metabolome; the biology of fungal RNA and epigenetics; protein expression, homologous as well as heterologous; fungal host/substrate relations; physiology, especially of extremophiles; and, not the least, the extent of global fungal biodiversity. …”
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Osteoprotegerin as an Emerging Biomarker of Carotid Artery Stenosis? A Scoping Review with Meta-Analysis by Jerzy Chudek, Marta Pośpiech, Anna Chudek, Michał Holecki, Monika Puzianowska-Kuźnicka

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Prediction of Insulin Resistance and Impaired Fasting Glucose Based on Sex Hormone-Binding Globulin (SHBG) Levels in Polycystic Ovary Syndrome by Aleksandra Biernacka-Bartnik, Piotr Kocełak, Aleksander Jerzy Owczarek, Piotr Choręza, Monika Puzianowska-Kuźnicka, Leszek Markuszewski, Paweł Madej, Jerzy Chudek, Magdalena Olszanecka-Glinianowicz

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Exploring the utility of snRNA-seq in profiling human bladder tissue: A comprehensive comparison with scRNA-seq by Briana Santo, Emily E. Fink, Alexandra E. Krylova, Yi-Chia Lin, Mohamed Eltemamy, Alvin Wee, Oliver Wessely, Byron H. Lee, Angela H. Ting

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Computational biology and artificial intelligence in mRNA vaccine design for cancer immunotherapy by Saber Imani, Xiaoyan Li, Keyi Chen, Mazaher Maghsoudloo, Parham Jabbarzadeh Kaboli, Mehrdad Hashemi, Mehrdad Hashemi, Saloomeh Khoushab, Saloomeh Khoushab, Xiaoping Li

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