Small-Molecule Hormones: Molecular Mechanisms of Action by Monika Puzianowska-Kuznicka, Eliza Pawlik-Pachucka, Magdalena Owczarz, Monika Budzińska, Jacek Polosak

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Mesenchymal stromal cells promote the formation of lung cancer organoids via Kindlin-2 by Zhilin Sui, Xianxian Wu, Jiaxin Wang, ShihJye Tan, Chao Zhao, Zhentao Yu, Chuanyue Wu, Xiaoxiao Wang, Ling Guo

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Transketolase attenuates the chemotherapy sensitivity of glioma cells by modulating R-loop formation by Minjie Fu, Mengli Zhang, Licheng Zhang, Yuan Feng, Chao Gao, Hao Xu, Jinsen Zhang, Huaichao Zhang, Tianping Peng, Youjun Chu, Yonghe Wu, Pu Wang, Dan Ye, Ying Mao, Wei Hua

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Differentiation of high risk prostate cancer with a facile urinary exosome detection workflow by Shuai Qiu, Yue Li, Zheng Zhang, Chunchang Li, Haoyu Wang, Ao Chen, Zhi Yan, Yang Liu, Zifei Li, Hua Huang, Yi Liu, Yiqi Seow, Ruibing Chen, Jinhong Guo, Simeng Wen, Jing Tian, Hongtuan Zhang, Ranlu Liu, Gang Han, Baolong Wang, Yong Wang, Yuanjie Niu, HaiFang Yin

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DAMPs prognostic signature predicts tumor immunotherapy, and identifies immunosuppressive mechanism of pannexin 1 channels in pancreatic ductal adenocarcinoma by Qianxue Wu, Qian Xiao, Qian Xiao, Xin Tang, Liuying Li, Daqiang Song, Yang Zhou, Benhua Li, Benhua Li, Guosheng Ren, Guosheng Ren, Fang Luo

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Autophagic flux modulates tumor heterogeneity and lineage plasticity in SCLC by Yujie Hao, Mingchen Li, Wenxu Liu, Zhenyi Ma, Zhe Liu, Zhe Liu, Zhe Liu

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HCC Heterogeneity: Molecular Pathogenesis and Clinical Implications by Emilia Fransvea, Angelo Paradiso, Salvatore Antonaci, Gianluigi Giannelli

“…A novel approach to mapping these differences is by investigating the epigenetics associated with certain clinical aspects.…”
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Simple Meets Single: The Application of CRISPR/Cas9 in Haploid Embryonic Stem Cells by Zixi Yin, Lingyi Chen

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Telomere Length in Elderly Caucasians Weakly Correlates with Blood Cell Counts by Ewa Gutmajster, Joanna Witecka, Magdalena Wyskida, Justyna Koscinska-Marczewska, Malgorzata Szwed, Magdalena Owczarz, Malgorzata Mossakowska, Andrzej Milewicz, Monika Puzianowska-Kuznicka, Jan Zejda, Andrzej Wiecek, Jerzy Chudek, Aleksander L. Sieron

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Targeting Apoptosis Pathways in Cancer with Alantolactone and Isoalantolactone by Azhar Rasul, Muhammad Khan, Muhammad Ali, Jiang Li, Xiaomeng Li

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Liver transcriptomics-metabolomics integration reveals biological pathways associated with fetal programming in beef cattle by Guilherme Henrique Gebim Polizel, Simara Larissa Fanalli, Wellison J. S. Diniz, Aline Silva Mello Cesar, Nara Regina Brandão Cônsolo, Heidge Fukumasu, Angela Cánovas, Arícia Christofaro Fernandes, Barbara Carolina Teixeira Prati, Édison Furlan, Gabriela do Vale Pombo, Miguel Henrique de Almeida Santana

“…This study highlights the significant impact of prenatal nutrition on the liver tissue of Nelore bulls, shedding light on critical metabolic pathways and hub components related to energy and protein metabolism, as well as immune system and epigenetics.…”
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Detection of reproducible liver cancer specific ligand-receptor signaling in blood by Aram Safrastyan, Aram Safrastyan, Damian Wollny, Damian Wollny, Damian Wollny

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The Emerging Role of Mesenchymal Stem Cells in Vascular Calcification by Changming Xie, Liu Ouyang, Jie Chen, Huanji Zhang, Pei Luo, Jingfeng Wang, Hui Huang

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Noncoding RNAs in Health and Disease by Davide Barbagallo, Gaetano Vittone, Massimo Romani, Michele Purrello

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Concise Review: The Regulatory Mechanism of Lysine Acetylation in Mesenchymal Stem Cell Differentiation by Hong Yang, Yuexia Liu, Xuanchen Liu, Huihui Gu, Jing Zhang, Chao Sun

“…Nowadays, the use of MSCs has attracted considerable attention in the global science and technology field, with the self-renewal and multidirectional differentiation potential for diabetes, obesity treatment, bone repair, nerve repair, myocardial repair, and so on. Epigenetics plays an important role in the regulation of mesenchymal stem cell differentiation, which has become a research hotspot in the medical field. …”
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Editorial: Community series in adenosine pathways in cancer immunity and immunotherapy, volume II by Junjiang Fu, Luca Antonioli, Xiaoli Zheng, Ali H. El-Far

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Colonic Mucosal Epigenome and Microbiome Development in Children and Adolescents by R. Alan Harris, Rajesh Shah, Emily B. Hollister, Rune Rose Tronstad, Nils Hovdenak, Reka Szigeti, James Versalovic, Richard Kellermayer

“…Epigenetic and microbiome changes during pediatric development have been implicated as important elements in the developmental origins of inflammatory bowel diseases (IBDs) including Crohn’s disease (CD) and ulcerative colitis (UC), which are linked to early onset colorectal cancer (CRC). …”
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Prenatal visualization of the fetal uterus in routine 2D ultrasound examination by Pedro Azumendi, Marisa Borenstein, Jesús Salvador Jiménez, Ernesto González-Mesa, Carlos Corrales, Guillermo Azumendi, Ignacio Alonso-Usabiaga, Juan Gómez-Salgado, Francisco Javier Fernández-Carrasco

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ERK activation dynamics in maturing oocyte controls embryonic nuclear divisions in Caenorhabditis elegans by Han Bit Baek, Debabrata Das, Shin-Yu Chen, Hongyuan Li, Swathi Arur

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Effect of neutrophils on tumor immunity and immunotherapy resistance with underlying mechanisms by Jiali Yao, Linlin Ji, Guang Wang, Jin Ding

“…Secondly, we review the mechanisms by which neutrophils affect drug resistance in tumor immunotherapy from the aspects of the immune microenvironment, tumor antigens, and epigenetics. Finally, we propose several promising strategies for overcoming tumor immunotherapy resistance by targeting neutrophils and provide new research ideas in this area.…”
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