Showing 541 - 560 results of 755 for search '"epigenetic"', query time: 0.04s Refine Results
  1. 541

    Paternal metabolic and cardiovascular programming of their offspring: A systematic scoping review. by Claudia Eberle, Michaela F Kirchner, Raphaela Herden, Stefanie Stichling

    Published 2020-01-01
    “…Moreover, there is also lotsof evidence that underlining mechanisms, such as molecular as well as epigenetic changes may alter the intrauterine environment leading to cardio-metabolic diseases in their offspring postnatal. …”
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    Article
  2. 542

    KAT2B inhibits proliferation and invasion via inactivating TGF-β/Smad3 pathway-medicated autophagy and EMT in epithelial ovarian cancer by Yuqin Yao, Yuna Niu, Honggui Zhou, Min Yong

    Published 2025-01-01
    “…Abstract Lysine acetyltransferase 2B (KAT2B) plays a crucial role in epigenetic regulation and tumor pathogenesis. Our study investigates KAT2B’s function in epithelial ovarian cancer (EOC) using in vivo and in vitro methods. …”
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    Article
  3. 543

    Fate and long-lasting therapeutic effects of mesenchymal stromal/stem-like cells: mechanistic insights by Akram Hoseinzadeh, Seyed-Alireza Esmaeili, Reza Sahebi, Anahita Madani Melak, Mahmoud Mahmoudi, Maliheh Hasannia, Rasoul Baharlou

    Published 2025-02-01
    “…Recent studies have provided evidence that the uptake of ABs with a distinct genetic component can induce changes in gene expression through the process of epigenetic remodeling. This phenomenon, known as ‘trained immunity’, has a significant impact on immunometabolism processes. …”
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    Article
  4. 544

    DNA Methylation Profiles of Blood Cells Are Distinct between Early-Onset Obese and Control Individuals by Je-Keun Rhee, Jin-Hee Lee, Hae Kyung Yang, Tae-Min Kim, Kun-Ho Yoon

    Published 2017-03-01
    “…Obesity is a highly prevalent, chronic disorder that has been increasing in incidence in young patients. Both epigenetic and genetic aberrations may play a role in the pathogenesis of obesity. …”
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    Article
  5. 545

    Mechanisms and environmental factors shaping the ecosystem of brain macrophages by Silvia Penati, Simone Brioschi, Zhangying Cai, Claudia Z. Han, Claudia Z. Han, Marco Colonna, Marco Colonna

    Published 2025-01-01
    “…Microglia and BAMs are phenotypically and epigenetically distinct and exhibit highly specialized functions tailored to their environmental niches. …”
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    Article
  6. 546

    Pan-cancer analysis shows that TNFSF4 is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including liver cancer by Zhaoda Deng, Lincheng Li, Zihe Meng, Guineng Zeng, Rui Cao, Rong Liu

    Published 2025-01-01
    “…Online websites and databases were used to investigate TNFSF4’s biological function, epigenetic modifications, genetic alterations, and tumor immunity. …”
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    Article
  7. 547

    <i>Phyllanthus emblica</i> Prevents Adipogenesis by Regulating Histone Acetylation by Seon Kyeong Park, Yu Geon Lee, Jae-In Lee, Min-Sun Kim, Jae-Ho Park, Jin-Taek Hwang, Min-Yu Chung

    Published 2025-01-01
    “…This study aimed to determine the preventive effect of <i>P. emblica</i> on obesity by evaluating the inhibition of adipogenesis and the related regulatory epigenetic mechanisms during 3T3-L1 differentiation. …”
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    Article
  8. 548

    Lack of GAGA protein in Trl mutants causes massive cell death in Drosophila spermatogenesis and oogenesis by N. V. Dorogova, A. E. Zubkova, E. V. Fedorova, E. U. Bolobolova, E. M. Baricheva

    Published 2021-06-01
    “…Drosophila protein GAGA (GAF) is a factor of epigenetic transcription regulation of a large group of genes with a wide variety of cellular functions. …”
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    Article
  9. 549

    Pan-cancer analysis of SOX2: Prognostic implications and potential as a therapeutic target in immune checkpoint modulation by Shoukai Yu, Lingmei Qian, Liling Xu, Jun Ma

    Published 2025-02-01
    “…This study investigates SOX2 genetic, transcriptomic, and epigenetic alterations across over 30 cancer types. …”
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    Article
  10. 550

    Tissue-specific effects of benzo[a]pyrene and DDT on microRNA expression profile in female rats by D. S. Ushakov, T. S. Kalinina, A. S. Dorozhkova, V. Y. Ovchinnikov, L. F. Gulyaeva

    Published 2018-04-01
    “…Many xenobiotics in the human environment, such as benzo[a]pyrene (B(a)P) and dichlorodiphenyltrichloroethane (DDT), may act as non-genotoxic carcinogens through epigenetic mechanisms, including changes in microRNA expression profile. …”
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    Article
  11. 551

    Methylation Status of Vitamin D Receptor Gene Promoter in Benign and Malignant Adrenal Tumors by Catia Pilon, Andrea Rebellato, Riccardo Urbanet, Vincenza Guzzardo, Rocco Cappellesso, Hironobu Sasano, Ambrogio Fassina, Francesco Fallo

    Published 2015-01-01
    “…Downregulation of VDR gene expression may result from epigenetics events, that is, methylation of cytosine nucleotide of CpG islands in VDR gene promoter. …”
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    Article
  12. 552

    Molecular genetic basis of epidermolysis bullosa by Yu. Yu. Kotalevskaya, V. A. Stepanov

    Published 2023-03-01
    “…In general, the study of clinical, genetic and ultrastructural changes in EB has significantly expanded the understanding of the natural history of the disease and supplemented the data on genotype-phenotype correlations, promotes the search and study of epigenetic and non-genetic disease modifier factors, and also allows developing approaches to radical treatment of the disease. …”
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    Article
  13. 553

    Emerging roles of circular RNAs on the regulation of production traits in chicken by Guishuang You, Hong Long, Xiaoxu Shen, Huadong Yin, Shibin Zhang

    Published 2025-01-01
    “…This performance is determined by various production traits that are primarily influenced by multiple factors, including epigenetics—a critical aspect of gene regulation. Circular RNAs (circRNAs), a unique class of non-coding RNAs, have emerged as key epigenetic regulators. …”
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    Article
  14. 554

    RNA modification writer-based immunological profile and genomic landscape of tumor microenvironment in lung adenocarcinoma by Qiang Xu, Lingyu Kong, Zhezhu Han, Xiuying Jin, Mingyan Ding, Zhengri Piao, Songnan Zhang

    Published 2025-01-01
    “…The potential for undoing epigenetic changes may develop novel therapeutic and prognostic approaches. …”
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    Article
  15. 555

    Signatures of selection and candidate genes for adaptation to extreme environmental factors in the genomes of Turano-Mongolian cattle breeds by N. S. Yudin, A. A. Yurchenko, D. M. Larkin

    Published 2021-04-01
    “…Changes in the environment force populations of organisms to adapt to new conditions, either through phenotypic plasticity or through genetic or epigenetic changes. Signatures of selection, such as specific changes in the frequency of alleles and haplotypes, as well as the reduction or increase in genetic diversity, help to identify changes in the cattle genome in response to natural and artificial selection, as well as loci and genetic variants directly affecting adaptive and economically important traits. …”
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    Article
  16. 556

    CitGATA7 interact with histone acetyltransferase CitHAG28 to promote citric acid degradation by regulating the glutamine synthetase pathway in citrus by Xiahui Lin, Shaojia Li, Yanna Shi, Yuchen Ma, Yinchun Li, Haohan Tan, Bo Zhang, Changjie Xu, Kunsong Chen

    Published 2025-02-01
    “…While the transcriptional regulatory mechanisms of citric acid metabolism have been extensively studied, the understanding about the transcriptional and epigenetic co-regulation mechanisms is limited. This study characterized a transcription factor, CitGATA7, which directly binds to and activates the expression of genes associated with the glutamine synthetase pathway regulating citric acid degradation. …”
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    Article
  17. 557

    Microbial signatures in head and neck squamous cell carcinoma: an in silico study by Loganathan KAVITHA, Manogaran KUZHALMOZHI, Jayaseelan VIJAYASHREE PRIYADHARSINI, Arunachalam ARUN KUMAR, Krishna Mohan Rao UMADEVI, Kannan RANGANATHAN

    Published 2025-02-01
    “…Methodology The microbe-host transcriptomic, proteomic, and epigenetic analyses of HNSCC and GI carcinomas were performed using The Cancer Microbiome Atlas (TCMA) database. …”
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    Article
  18. 558

    Butyrate Supplementation Improves Intestinal Health and Growth Performance in Livestock: A Review by Wenting Chen, Qingshan Ma, Yan Li, Lin Wei, Zhenwei Zhang, Adnan Khan, Muhammad Zahoor Khan, Changfa Wang

    Published 2025-01-01
    “…Additionally, butyrate plays a role in the epigenetic regulation of gene expression through histone acetylation, influencing tissue development and immune modulation. …”
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    Article
  19. 559

    Comparison of Different Histone Deacetylase Inhibitors in Attenuating Inflammatory Pain in Rats by Yu Mao, Jing Zhou, Xuesheng Liu, Erwei Gu, Zhi Zhang, Wenjuan Tao

    Published 2019-01-01
    “…Histone deacetylase inhibitors (HDACIs), which interfere with the epigenetic process of histone acetylation, have shown analgesic effects in animal models of persistent pain. …”
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  20. 560

    MicroRNA Expression Profiling in Behçet’s Disease by Antonio Puccetti, Andrea Pelosi, Piera Filomena Fiore, Giuseppe Patuzzo, Claudio Lunardi, Marzia Dolcino

    Published 2018-01-01
    “…The combined analysis of deregulated miRNAs and BD transcriptome sheds light on some epigenetic aspects of BD identifying specific miRNAs, which may represent promising candidates as biomarkers and/or for the design of novel therapeutic strategies in BD.…”
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    Article