Showing 521 - 540 results of 974 for search '"epigenetic"', query time: 0.05s Refine Results
  1. 521

    Non-coding RNAs and exosomal ncRNAs in colorectal cancer by Yalda Zhoulideh

    Published 2025-02-01
    “…Abstract Colorectal cancer (CRC) is a complex disease with many genetic and epigenetic changes leading to dysregulation of cell signaling pathways. …”
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    Article
  2. 522

    Implications of intratumoral microbiota in tumor metastasis: a special perspective of microorganisms in tumorigenesis and clinical therapeutics by Lei Zhang, Xichu Duan, Yanhua Zhao, Dejiu Zhang, Yuan Zhang

    Published 2025-02-01
    “…Intratumoral microbiota can modulate tumor progression through multiple mechanisms, including regulating immune responses, inducing genomic instability and gene mutations, altering metabolic pathways, controlling epigenetic pathways, and disrupting cancer-related signaling pathways. …”
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  3. 523

    Prmt5 is essential for intestinal stem cell maintenance and homeostasis by Li Yang, Xuewen Li, Chenyi Shi, Bing Zhao

    Published 2025-02-01
    “…Abstract Intestinal homeostasis relies on the continuous renewal of intestinal stem cells (ISCs), which could be epigenetically regulated. While protein arginine methyltransferase 5 (Prmt5) is known to play a key role in multiple organs as an epigenetic modifier, its specific function in maintaining intestinal homeostasis remains to be elucidated. …”
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  4. 524

    ATP-Dependent Chromatin Remodeling Complex in the Lineage Specification of Mesenchymal Stem Cells by Wen Du, Daimo Guo, Wei Du

    Published 2020-01-01
    “…ATP-dependent chromatin alteration is one form of epigenetic modifications that can regulate the transcriptional level of specific genes by utilizing the energy from ATP hydrolysis to reorganize chromatin structure. …”
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    Article
  5. 525

    Periconceptional Folate Deficiency and Implications in Neural Tube Defects by J. Safi, L. Joyeux, G. E. Chalouhi

    Published 2012-01-01
    “…Nutritional deficiencies are preventable etiological and epigenetic factors causing congenital abnormalities, first cause of infant mortality. …”
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    Article
  6. 526

    Molecular and Cellular Pathways Contributing to Joint Damage in Rheumatoid Arthritis by Qinghua Fang, Chun Zhou, Kutty Selva Nandakumar

    Published 2020-01-01
    “…Rheumatoid arthritis is a chronic autoimmune syndrome associated with several genetic, epigenetic, and environmental factors affecting the articular joints contributing to cartilage and bone damage. …”
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    Article
  7. 527

    Theoretical underpinnings and future research on academic stress in biological and educational perspectives by Wasis Wuyung Wisnu Brata, Hendra Susanto, Siti Zubaidah

    Published 2025-02-01
    “…The review identifies four key theoretical foundations: the neurocognitive aspects of stress and performance, the neurophysiology of stress, epigenetic regulation of stress, and stress and genetic variations. …”
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  8. 528

    Glioblastoma Multiforme Stem Cells by Irena Dimov, Deasanka Tasic-Dimov, Irena Conic, Vladisav Stefanovic

    Published 2011-01-01
    “…There are promising mounting data on providing new molecular targets and predictive markers of response, leading to more effective therapies of GBM, guided by patient-specific genetic and epigenetic profiling. However, the achievement of efficient GBMSC targeting also requires an adequate understanding of the unique microenvironment, and the relationship with the immune system in the central nervous system (CNS) and CNS tumors. …”
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  9. 529

    Stress Response and Perinatal Reprogramming: Unraveling (Mal)adaptive Strategies by Laura Musazzi, Jordan Marrocco

    Published 2016-01-01
    “…These changes are likely driven by epigenetic factors that lie at the core of the stress-response reprogramming in individuals with a history of perinatal stress. …”
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  10. 530

    The DNA Polymerase _-Primase Complex: Multiple Functions and Interactions by Marco Muzi-Falconi, Michele Giannattasio, Marco Foiani, Paolo Plevani

    Published 2003-01-01
    “…However, pol-prim seems to play additional roles in other complex cellular processes, such as the response to DNA damage, telomere maintenance, and the epigenetic control of higher order chromatin assembly.…”
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  11. 531

    Post infectious fatigue and circadian rhythm disruption in long-COVID and other infections: a need for further research by Achilleas Livieratos, Steven W. Lockley, Sotirios Tsiodras

    Published 2025-02-01
    “…., interleukin-6, tumor necrosis factor-alpha). Epigenetic changes, including DNA methylation at clock-related loci, particularly in peripheral tissues, further contribute to systemic circadian dysregulation. …”
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  12. 532

    Biological functions of 5-methylcytosine RNA-binding proteins and their potential mechanisms in human cancers by Tingting Zhao, Zhe Zhang, Zhuo Chen, Guozheng Xu, Yongxi Wang, Fang Wang

    Published 2025-02-01
    “…The 5-methylcytosine (m5C) modification is a crucial epigenetic RNA modification, which is involved in the post-transcriptional regulation of genes. …”
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  13. 533

    The Role of the NIS (SLC5A5) Gene in Papillary Thyroid Cancer: A Systematic Review by Rafael Martins de Morais, Alaor Barra Sobrinho, Calliandra Maria de Souza Silva, Jamila Reis de Oliveira, Izabel Cristina Rodrigues da Silva, Otávio de Toledo Nóbrega

    Published 2018-01-01
    “…Papillary thyroid cancer (PTC) is the most common thyroid malignancy. Genetic and epigenetic alterations play a decisive role in the onset of several human neoplasms. …”
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  14. 534

    Non-metric variations in individuals who died during the perinatal period in past populations: recording protocol and comparative data by Caroline Partiot, Dominique Castex, Valérie Delattre, Bruno Maureille, Mark Guillon

    Published 2023-08-01
    “…Non-metric variations, also referred to as "epigenetic variations" or asymptomatic bone variants, are bone or dental phenotypic variants of unknown origin, with no known pathological etiology. …”
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  17. 537

    Implications of noncoding RNAs for cancer therapy: Are we aiming at the right targets? by Amil Shah

    Published 2025-01-01
    “…It now appears that dual epigenetic regulatory systems exist in higher eukaryotic cells: a ncRNA network that governs essential cell functions, like cell fate decision and maintenance of homeostasis, and a protein-based system that presides over core physiological processes, like cell division and genomic maintenance. …”
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  18. 538

    Spatial stochastic models of cancer: Fitness, migration, invasion by Natalia L. Komarova

    Published 2013-03-01
    “…Cancer progression is driven by genetic and epigenetic events giving rise to heterogeneity of cellphenotypes, and by selection forces that shape the changingcomposition of tumors. …”
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  19. 539

    Facioscapulohumeral muscular dystrophy: a review of pathogenesis, clinical symptoms, and treatment by T. Mikalauskas, B. Burnytė

    Published 2023-10-01
    “…The first type is characterised by a reduction in D4Z4 repeats, while the second type is characterised by mutations in genes encoding epigenetic regulators such as SMCHD1. In recent years, significant progress has been made in understanding the pathogenesis, clinical features, and progression of the disease, but there is still no specific treatment due to the obstacles in the development of gene therapy. …”
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  20. 540

    Cashmere cyclic growth affected by different photoperiods alters DNA methylation patterns by Ruoyang Zhao, Tiecheng Wu, Jun Yin, Tao Wang, Yunmei He, Yahan Wu, Yulin Gao, Bin Liu

    Published 2024-12-01
    “…Whole-genome bisulfite sequencing was used to study epigenetic differences in hair follicles from Inner Mongolia Albas cashmere goats during long and short photoperiods. …”
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