Label-Free Surface-Enhanced Raman Scattering for Genomic DNA Cytosine Methylation Reading by Kazi Morshed Alom, Anastasiia Tukova, Nana Lyu, Alison Rodger, Yuling Wang

“…DNA methylation has been widely studied with the goal of correlating the genome profiles of various diseases with epigenetic mechanisms. Multiple approaches have been developed that employ extensive steps, such as bisulfite treatments, polymerase chain reactions (PCR), restriction digestion, sequencing, mass analysis, etc., to identify DNA methylation. …”
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Maternal asthma imprints fetal lung ILC2s via glucocorticoid signaling leading to worsened allergic airway inflammation in murine adult offspring by Tomoaki Takao, Ako Matsui, Chie Kikutake, Keiko Kan-o, Azusa Inoue, Mikita Suyama, Isamu Okamoto, Minako Ito

“…Furthermore, these offspring carry overlapping chromatin-accessible altered regions, including glucocorticoid receptor-binding regions in their lung ILC2s both at the fetal stage and adulthood, suggesting persistent prenatal epigenetic changes. Moreover, maternal exposure to glucocorticoids has similar effects on fetal lung ILC2s and contributes to allergen-induced lung inflammation during adulthood. …”
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Twist-Induced Epithelial-to-Mesenchymal Transition Confers Specific Metabolic and Mitochondrial Alterations by Haleigh N. Parker, Kayla L. Haberman, Tolulope Ojo, Juli Watkins, Adhwaitha Nambiar, Kayla Morales, Bernd Zechmann, Joseph H. Taube

“…Cells undergo significant epigenetic and phenotypic change during the epithelial-to-mesenchymal transition (EMT), a process observed in development, wound healing, and cancer metastasis. …”
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Possible impact of use of a ketogenic diet in pregnancy on the fetus: Review of animal and human studies by Agata Miłosz, Justyna Michalczyk, Iwona Morawik, Klaudia Długoborska, Monika Gesek

“…In addition, it may lead to epigenetic changes in the fetus that affect the child's health and functioning in adulthood [2]. …”
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Cellular senescence-associated genes in rheumatoid arthritis: Identification and functional analysis. by You Ao, Qing Lan, Tianhua Yu, Zhichao Wang, Jing Zhang

“…Rheumatoid arthritis (RA), a long-term autoinflammatory condition causing joint damage and deformities, involves a multifaceted pathogenesis with genetic, epigenetic, and immune factors, including early immune aging. …”
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Chidamide Suppresses the Growth of Cholangiocarcinoma by Inhibiting HDAC3 and Promoting FOXO1 Acetylation by Yongpan Li, Jujia Zheng, Qiang Huo, Zhongchao Chen, Jun Chen, Xiangwei Xu

“…Inhibitors for histone deacetylases (HDACs) have been identified as epigenetic drug targets to treat a variety of malignancies through several molecular mechanisms. …”
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Molecular techniques for cancer diagnostics by Vimal Kishor Singh, Ramesh Chandra

“…Recent research reported vast genetic and epigenetic heterogeneity, differences in the gene-expression profiles, and signal transduction networks in a broad range of cancers. …”
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Triplet Therapy with PD-1 Blockade, Histone Deacetylase Inhibitor, and DNA Methyltransferase Inhibitor Achieves Radiological Response in Refractory Double-Expressor Diffuse Large B... by Runhui Zheng, Xiaobo Chen, Chunyan Wang, Pengfei Qin, Huo Tan, Xiaodan Luo

“…Immune checkpoint blockade and epigenetic drugs have been widely used, but the efficacy of different combined applications varied. …”
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RIP mutated ITS genes in populations of Ophiocordyceps sinensis and their implications for molecular systematics by Yi Li, Lan Jiang, Ke Wang, Hai-Jun Wu, Rui-Heng Yang, Yu-Jing Yan, Kathryn E. Bushley, David L. Hawksworth, Zujian Wu, Yi-Jian Yao

“…This is a process that detects and mutates repetitive DNA and frequently leads to epigenetic silencing, and these mutations have been interpreted as pseudogenes. …”
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The Polycystic Ovary Syndrome and the Metabolic Syndrome: A Possible Chronobiotic-Cytoprotective Adjuvant Therapy by Eduardo Spinedi, Daniel P. Cardinali

“…., chronodisruption) and genetic/epigenetic factors may also play relevant roles in syndrome development. …”
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Mechanism of Inflammation in Age-Related Macular Degeneration by Francesco Parmeggiani, Mario R. Romano, Ciro Costagliola, Francesco Semeraro, Carlo Incorvaia, Sergio D’Angelo, Paolo Perri, Paolo De Palma, Katia De Nadai, Adolfo Sebastiani

“…Risk factors of AMD are heterogeneous, mainly including increasing age and different genetic predispositions, together with several environmental/epigenetic factors, that is, cigarette smoking, dietary habits, and phototoxic exposure. …”
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Clinical Features and Genetic Background of the Periodic Fever Syndrome with Aphthous Stomatitis, Pharyngitis, and Adenitis: A Single Center Longitudinal Study of 81 Patients by Daša Perko, Maruša Debeljak, Nataša Toplak, Tadej Avčin

“…Our data suggest that PFAPA could be the result of multiple low-penetrant variants in different genes in combination with epigenetic and environmental factors leading to uniform clinical picture.…”
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N7-methylguanosine modification in cancers: from mechanisms to therapeutic potential by Qihui Wu, Xiaodan Fu, Guoqian Liu, Xiaoyun He, Yimin Li, Chunlin Ou

“…Abstract N7-methylguanosine (m7G) is an important RNA modification involved in epigenetic regulation that is commonly observed in both prokaryotic and eukaryotic organisms. …”
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Structure and evolution of metapolycentromeres by E. O. Grishko, P. M. Borodin

“…The metapolycentromeres may vary in the number of centromeric domains and in their genetic content and epigenetic modifications. However, these variations do not seem to affect their function. …”
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Effect of The Duration of The Diagnosis on DNA Methylation Changes in Three Different Diabetic Genes in Type 2 Diabetes Mellitus by Harem Othman Smail

“… The primary epigenetic alteration is DNA methylation. This study examined variations in DNA methylation in patients with type 2 diabetes at various time intervals, concentrating on the  Calpain-10 (CAPN10), ATP binding cassette subfamily C member 8 (ABCC8), and  Transcription factor 7-like 2 (TCF7L2) genes. …”
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Whole Exome Sequencing Reveals Rare Variants in Genes Associated with Metabolic Disorders in Women with PCOS by Priyal Sharma, Ashutosh Halder, Manish Jain, Manish Tripathi

“…Background: Polycystic ovary syndrome (PCOS) is a complex genetic trait, the pathogenesis of which is governed by an interplay of genetic and epigenetic factors. However, the aetiology of PCOS is not fully understood. …”
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m5C‐TNKmer: Identification of 5‐Methylated Base Cytosine of Ribonucleic Acid Using Supervised Machine Learning Techniques by Shahid Qazi, Dilawar Shah, Mohammad Asmat Ullah Khan, Shujaat Ali, Mohammad Abrar, Asfandyar Khan, Muhammad Tahir

“…ABSTRACT 5‐Methylcytosine (m5C) is a widely recognized epigenetic modification in ribonucleic acid (RNA), catalyzed by methyltransferases. …”
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Endothelial Progenitor Cells in Diabetic Microvascular Complications: Friends or Foes? by Cai-Guo Yu, Ning Zhang, Sha-Sha Yuan, Yan Ma, Long-Yan Yang, Ying-Mei Feng, Dong Zhao

“…In this review, we first illustrate how hyperglycemia induces metabolic and epigenetic changes in EPCs, which exerts deleterious impact on their number and function. …”
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siRNA therapeutics for effective management of rheumatoid arthritis by Vishakha R. Chakole, Tathagata Dutta, Priyankar Sen

“…Several treatments are available for RA, including analgesics, corticosteroids, DMARDs, biological agents, combinational therapy, epigenetic and cell therapies which play a crucial role in preventing joint function deterioration, inflammation, synovial edema, etc. …”
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Intercellular communication is crucial in the regulation of healthy aging via exosomes by Huifang Sun, Tengyuan Xia, Shuting Ma, Tao Lv, Yuhong Li

“…The hallmarks of aging encompass a variety of molecular categories (genomic, telomeric, and epigenetic), organelles (proteostasis, autophagy, and mitochondria), cellular components (including stem cells), systems (such as intercellular communication and chronic inflammation), and environmental factors (dysbiosis and nutrient sensing). …”
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