Showing 361 - 380 results of 974 for search '"epigenetic"', query time: 0.04s Refine Results
  1. 361

    DNA methylation, histone acetylation in the regulation of memory and its modulation during aging by Padmanabh Singh, Vijay Paramanik

    Published 2025-01-01
    “…These epigenetic modifications, in turn, are regulated by physiology and metabolism. …”
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    Article
  2. 362
  3. 363

    DNA Methylation in Skeletal Muscle Stem Cell Specification, Proliferation, and Differentiation by Rhianna C. Laker, James G. Ryall

    Published 2016-01-01
    “…An unresolved and critically important question in skeletal muscle biology is how muscle stem cells initiate and regulate the genetic program during muscle development. Epigenetic dynamics are essential for cellular development and organogenesis in early life and it is becoming increasingly clear that epigenetic remodeling may also be responsible for the cellular adaptations that occur in later life. …”
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    Article
  4. 364

    A SuperLearner-based pipeline for the development of DNA methylation-derived predictors of phenotypic traits. by Dennis Khodasevich, Nina Holland, Lars van der Laan, Andres Cardenas

    Published 2025-02-01
    “…<h4>Background</h4>DNA methylation (DNAm) provides a window to characterize the impacts of environmental exposures and the biological aging process. Epigenetic clocks are often trained on DNAm using penalized regression of CpG sites, but recent evidence suggests potential benefits of training epigenetic predictors on principal components.…”
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  5. 365
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  7. 367

    Methylation-Demethylation Dynamics: Implications of Changes in Acute Kidney Injury by Anubhav Chakraborty, Pragasam Viswanathan

    Published 2018-01-01
    “…Over the years, the epigenetic landscape has grown increasingly complex. …”
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    Article
  8. 368

    Methods of massive parallel reporter assays for investigation of enhancers by S. E. Romanov, D. A. Kalashnikova, P. P. Laktionov

    Published 2021-06-01
    “…The development of high-throughput genomic assays has made it possible to significantly accelerate the accumulation of information about the characteristic epigenetic properties of regulatory elements. In combination with high-throughput studies focused on the genome-wide distribution of epigenetic marks, regulatory proteins and the spatial structure of chromatin, this significantly expands the understanding of the principles of epigenetic regulation of genes and allows potential regulatory elements to be searched for in silico. …”
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    Article
  9. 369

    Oxidative Stress and DNA Methylation in Prostate Cancer by Krishna Vanaja Donkena, Charles Y. F. Young, Donald J. Tindall

    Published 2010-01-01
    “…Epigenetics affects genetic regulation, cellular differentiation, embryology, aging, cancer, and other diseases. …”
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    Article
  10. 370

    Chromatin Modifying Agents in the In Vitro Production of Bovine Embryos by Fabio Morato Monteiro, Clara Slade Oliveira, Letícia Zoccolaro Oliveira, Naiara Zoccal Saraiva, Maria Eugênia Zerlotti Mercadante, Flavia Lombardi Lopes, Daniel Robert Arnold, Joaquim Mansano Garcia

    Published 2011-01-01
    “…Therefore, proper knowledge of epigenetic reprogramming is necessary to prevent possible epigenetic errors and to improve efficiency and the use of in vitro fertilization and cloning technologies in cattle and other species.…”
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    Article
  11. 371

    regionalpcs improve discovery of DNA methylation associations with complex traits by Tiffany Eulalio, Min Woo Sun, Olivier Gevaert, Michael D. Greicius, Thomas J. Montine, Daniel Nachun, Stephen B. Montgomery

    Published 2025-01-01
    “…Abstract We have developed the regionalpcs method, an approach for summarizing gene-level methylation. regionalpcs addresses the challenge of deciphering complex epigenetic mechanisms in diseases like Alzheimer’s disease. …”
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  12. 372

    Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity by Dalia Ali, Elna P. Chalisserry, Muthurangan Manikandan, Rimi Hamam, Musaad Alfayez, Moustapha Kassem, Abdullah Aldahmash, Nehad M. Alajez

    Published 2018-01-01
    “…Herein, we investigated the epigenetic effect of romidepsin, a small molecule dual inhibitor targeting HDAC1 and HDAC2 identified through an epigenetic library functional screen. …”
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  13. 373

    Genomic Imprinting and Cancer: From Primordial Germ Cells to Somatic Cells by Adele Murrell

    Published 2006-01-01
    “…Cancer is a disease of aberrant cell growth and is characterised by genetic mutations and epigenetic changes such as DNA methylation. The mechanisms whereby imprinting is maintained in somatic cells and then erased and reset in the germline parallels epigenetic changes that cancer cells undergo. …”
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  14. 374

    Longitudinal genetic studies of cognitive characteristics by R. N. Mustafin, A. V. Kazantseva, R. F. Enikeeva, S. B. Malykh, E. K. Khusnutdinova

    Published 2020-03-01
    “…The appropriate correction of epigenetic factors related to environmental differences in cognitive abilities requires to determine the mechanisms of chromatin modifications and variations in DNA methylation. …”
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    Article
  15. 375

    IL-13 Augments Histone Demethylase JMJD2B/KDM4B Expression Levels, Activity, and Nuclear Translocation in Airway Fibroblasts in Asthma by Khuloud Bajbouj, Mahmood Y. Hachim, Rakhee K. Ramakrishnan, Huwaida Fazel, Jumana Mustafa, Shahed Alzaghari, Mahmoud Eladl, Jasmin Shafarin, Ronald Olivenstein, Qutayba Hamid

    Published 2021-01-01
    “…Asthma is one of the most common obstructive pulmonary diseases worldwide. Epigenetic alterations, including DNA methylation and histone modifications, have been reported to contribute to asthma pathogenesis. …”
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    Article
  16. 376
  17. 377

    Role of Cold atmospheric plasma in cancer management by Shrikant B. Mali

    Published 2024-03-01
    “…This article discusses the impact of CAP on epigenetic changes, non-coding RNA expression, and DNA damage, and its synergy with conventional pharmaceuticals. …”
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    Article
  18. 378

    Allele-specific methylation of SSTR4 associated with aging and cognitive functions in patients with schizophrenia. by Rongrong Zhao, Huihui Shi, Yanqiu Wang, Tao Jiang, Yahui Xu

    Published 2025-01-01
    “…However, the role of genetic-epigenetic interactions involving SSTR4 in patients with schizophrenia remains unexplored. …”
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  19. 379

    Genetic background and embryonic temperature affect DNA methylation and expression of myogenin and muscle development in Atlantic salmon (Salmo salar). by Erik Burgerhout, Maren Mommens, Hanne Johnsen, Arnfinn Aunsmo, Nina Santi, Øivind Andersen

    Published 2017-01-01
    “…Here we studied the epigenetic effects of embryonic temperature and genetic background on body growth, muscle cellularity and myogenin expression in farmed Atlantic salmon (Salmo salar). …”
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  20. 380

    Long Noncoding RNAs, Chromatin, and Development by Daniel P. Caley, Ryan C. Pink, Daniel Trujillano, David R. F. Carter

    Published 2010-01-01
    “…This differential expression is regulated at the epigenetic level by chromatin modifications, such as DNA and histone methylation, which interact with structural and enzymatic proteins, resulting in the activation or silencing of any given gene. …”
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