Why and how should we simulate platform trials? Learnings from EU-PEARL by Elias Laurin Meyer, Tobias Mielke, Marta Bofill Roig, Michaela Maria Freitag, Peter Jacko, Pavla Krotka, Peter Mesenbrink, Tom Parke, Sonja Zehetmayer, Dario Zocholl, Franz König

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Feasibility of screening for cognitive impairment among older persons and referral by community health workers in Wakiso district, Uganda by Racheal Alinaitwe, Seggane Musisi, David Mukunya, Yvette Wibabara, Byamah B Mutamba, Noeline Nakasujja

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Utilization of a Joint Point Regression Model for Predicting Mortality Rates of Common Cancers in Babol City by Pouyan Ebrahimi, Sara Khaleghi, Mohebat Vali, Sahar Delavari, Soraya Khafri, Mohsen Karami, Layla Shojaie, Hossein‐Ali Nikbakht

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Sex and outcomes of patients with microsatellite instability-high and BRAF V600E mutated metastatic colorectal cancer receiving immune checkpoint inhibitors by Michael Hoffmeister, Hermann Brenner, Chiara Cremolini, Sara Lonardi, Filippo Pietrantonio, Julien Taieb, David Tougeron, Robyn L Ward, Marco Vitellaro, Thierry André, Pierre Laurent-Puig, Jitendra Jonnagaddala, Francesca Bergamo, Raghav Sundar, Claire Gallois, Michael J Overman, Jakob Nikolas Kather, Lisa Salvatore, Romain Cohen, Rossana Intini, Priya Jayachandran, Miriam Koopman, Javier Ros, Marwan Fakih, Vincenzo Nasca, Giacomo Mazzoli, Jeanine M L Roodhart, Filippo Ghelardi, Elena Elez, Durgesh Wankhede, Marta Ligero, Joseph Zhao, Koen Zwart, Jeroen Derksen, Nicholas Hawkins, Javier Carmona

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Reactogenicity and Immunogenicity Against MPXV of the Intradermal Administration of Modified Vaccinia Ankara Compared to the Standard Subcutaneous Route by Valentina Mazzotta, Pierluca Piselli, Alessandro Cozzi Lepri, Giulia Matusali, Eleonora Cimini, Rozenn Esvan, Francesca Colavita, Roberta Gagliardini, Stefania Notari, Alessandra Oliva, Silvia Meschi, Rita Casetti, Giulia Micheli, Licia Bordi, Alessandro Giacinta, Germana Grassi, Saba Gebremeskel Tekle, Claudia Cimaglia, Jessica Paulicelli, Alessandro Caioli, Paola Gallì, Giulia Del Duca, Miriam Lichtner, Loredana Sarmati, Enrica Tamburrini, Claudio Mastroianni, Alessandra Latini, Paolo Faccendini, Carla Fontana, Emanuele Nicastri, Andrea Siddu, Alessandra Barca, Francesco Vaia, Enrico Girardi, Fabrizio Maggi, Andrea Antinori

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Hantavirus Pulmonary Syndrome: Report of Four Alberta Cases by Ameeta E Singh, Denise H Werker, Lesia R Boychuk, Lilly J Miedzinski

“…A fourth case with milder illness was identified after epidemiological investigations. Ribavirin was used in one patient who experienced a successful outcome. …”
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Hypercapnia from Physiology to Practice by Amilkar Almanza-Hurtado, Camilo Polanco Guerra, María Cristina Martínez-Ávila, Diana Borré-Naranjo, Tomás Rodríguez-Yanez, Carmelo Dueñas-Castell

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Publisher Correction: Starvation-induced metabolic rewiring affects mTORC1 composition in vivo by Edgar Kaade, Simone Mausbach, Nina Erps, Marc Sylvester, Farhad Shakeri, Ron D. Jachimowicz, Volkmar Gieselmann, Melanie Thelen

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Prevalence and Predictors of Sleep Disturbance among Liver Diseases in Long-Term Transplant Survivors by Mamatha Bhat, Jonathan M Wyse, Erica Moodie, Peter Ghali, Nir Hilzenrat, Philip Wong, Marc Deschênes

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On the interaction between the immune system and an exponentially replicating pathogen by Alberto d'Onofrio

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Estimation of Hospital Potential Capacity and Basic Reproduction Number by Fei Wang, Linhua Wang, Peng Wang

“…Moreover, the proposed formula is also useful in the estimation of the basic reproduction number in epidemiology. The results can be contributed to the improvement of decision-making in the allocation of medical resources and the evaluation of the interventions and control efforts of the infectious disease.…”
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Description of Prescribing Practices in Patients with Upper Gastrointestinal Bleeding Receiving Intravenous Proton-Pump Inhibitors: A Multicentre Evaluation by Robert Enns, Christopher N Andrews, Martin Fishman, Michael Hahn, Kenneth Atkinson, Peter Kwan, Adrian Levy

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Chinese Guidelines for the Clinical Management of Obesity (2024 Edition) by Department of Medical Administration, National Health Commission of the People's Republic of China

“…Based on existing high-quality evidence-based medical literature, this guideline, by integrating multidisciplinary expert opinions, systematically addresses the etiology, epidemiology, definition, diagnostic criteria, treatment principles, and multi-disciplinary treatment models for obesity. …”
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Herpes Simplex Virus Type 1 is the Leading Cause of Genital Herpes in New Brunswick by Richard Garceau, Danielle Leblanc, Louise Thibault, Gabriel Girouard, Manon Mallet

“…INTRODUCTION: Little is known about the role of herpes simplex virus (HSV) type 1 (HSV1) in the epidemiology of genital herpes in Canada. Data on herpes viral cultures for two consecutive years obtained from L’Hôpital Dr GL Dumont, which performs all the viral culture testing in New Brunswick, were reviewed. …”
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Intravenous Proton Pump Inhibitors before Endoscopy in Bleeding Peptic Ulcer with High-Risk Stigmata: A Multicentre Comparative Study by Christopher N Andrews, Adrian Levy, Martin Fishman, Michael Hahn, Kenneth Atkinson, Peter Kwan, Robert Enns

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Pulmonary Hypertension Related to Left-Sided Cardiac Pathology by Todd L. Kiefer, Thomas M. Bashore

“…This article will review the literature as it pertains to the epidemiology, pathogenesis, and diagnosis of PH related to aortic valve disease, mitral valve disease, left ventricular systolic and diastolic dysfunction, and pulmonary veno-occlusive disease. …”
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Diabetes, TZDs, and Bone: A Review of the Clinical Evidence by Ann V. Schwartz

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Editorial: The role of parent-child interactions in developmental psychopathology: methodological and intervention challenges and opportunities by R. M. Pearson, R. M. Pearson, R. M. Pearson, B. Coetzee, T. J. Rochat, T. J. Rochat

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Self-Reported Practices in Opioid Management of Chronic Noncancer Pain: A Survey of Canadian Family Physicians by Michael JM Allen, Mark M Asbridge, Peter C MacDougall, Andrea D Furlan, Oleg Tugalev

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What Constitutes a Clinically Important Pain Reduction in Patients after Third Molar Surgery? by Wilhelmus JJM Martin, CE Ashton-James, NE Skorpil, MW Heymans, T Forouzanfar

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