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  1. 1821

    The structural characteristics of dietary fibers from Tremella fuciformis and their hypolipidemic effects in mice by Shanshan Zhang, Xinle Xu, Xu Cao, Tingting Liu

    Published 2023-03-01
    “…In this study, Tremella fuciformis residues as raw material, dietary fibers from tremella were prepared by multiple enzymes. The structure of dietary fibers from tremella was studied by Fourier transform infrared (FTIR), X-ray diffraction analysis (XRD) and scanning electron microscopy (SEM). …”
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    Article
  2. 1822

    Adaptability of clams to prolonged heatwaves: Influences on gene expression, antioxidant capacity, and histology of Chinese cyclina Cyclina sinensis by Meimei Liu, Zhichao Wang, Hongwei Ni, Wenqing Zhuo, Gaoyuan Yuan, Zhiguo Dong

    Published 2025-03-01
    “…The transcript levels of chaperones genes and antioxidant enzymes were up-regulated after acute heat stress treatment (35℃). …”
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  3. 1823

    Improving polyketide biosynthesis by rescuing the translation of truncated mRNAs into functional polyketide synthase subunits by Yan Liu, Chaoyi Song, Qingwen Cui, Hongluan Sun, Chanjuan Jiang, Ruofei Guo, Ruoting He, Zhen Li, Ji Luan, Hailong Wang

    Published 2025-01-01
    “…Abstract Modular polyketide synthases (mPKSs) are multidomain enzymes in bacteria that synthesize a variety of pharmaceutically important compounds. mPKS genes are usually longer than 10 kb and organized in operons. …”
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  4. 1824

    Improving Storability of “Nanfeng” Mandarins by Treating with Postharvest Hot Water Dipping by İbrahim Kahramanoğlu, Chuying Chen, Yao Chen, Jinyin Chen, Zengyu Gan, Chunpeng Wan

    Published 2020-01-01
    “…Regular measurements were performed to determine total soluble solid (TSS) content, titratable acid (TA) content, vitamin C (VC) content, total sugar content, respiration rate, malondialdehyde (MDA) content, and activities of superoxide dismutase (SOD) enzyme, polyphenoloxidase (PPO) enzyme, and peroxidase (POD) enzyme. …”
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  5. 1825

    Integrated metabolomics and proteomics analysis to provide insights into muscle atrophy of turbot Scophthalmus maximus by dietary Clostridium autoethanogenum protein by Shihui Pan, Nan Bai, Zezheng Qi, Chuwen Chen, Daisong Ma, Zhenlin Liang, Min Gu

    Published 2025-03-01
    “…Integrated analysis of metabolomics and proteomics showed that CAP negatively influenced the energy production by inhibiting the key enzymes of glycolysis and mitochondrial respiratory chain. …”
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    Article
  6. 1826

    Response mechanism of ethanol-tolerant Saccharomyces cerevisiae strain ES-42 to increased ethanol during continuous ethanol fermentation by Xue-Xue Ji, Quan Zhang, Bai-Xue Yang, Qing-Ran Song, Zhao-Yong Sun, Cai-Yun Xie, Yue-Qin Tang

    Published 2025-01-01
    “…At lower ethanol concentrations (nearly 70 g/L), genes involved in mitochondrial ribosomes, oxidative phosphorylation, the tricarboxylic acid (TCA) cycle, antioxidant enzymes, ergosterol synthesis, and glycerol biosynthesis were specifically upregulated compared to those at 60 g/L. …”
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    Article
  7. 1827

    Design, synthesis, and anti-inflammatory activity of 2H-1,4-benzoxazin-3(4H)-one derivatives modified with 1,2,3-triazole in LPS-induced BV-2 cells by Xixi Hou, Xixi Hou, Longfei Mao, Huibin Zhang, Lan Wang, Baoyu He, Jingjing Guo, Jianji Wang

    Published 2025-01-01
    “…Furthermore, they downregulated the transcription and protein levels of the inflammation-related enzymes iNOS and COX-2 in response to LPS stimulation. …”
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    Article
  8. 1828

    Sphingosine kinase 1 promotes M2 macrophage infiltration and enhances glioma cell migration via the JAK2/STAT3 pathway by Zihan Song, Zijun Zhao, Xuehua Liu, Yiran Song, Siyu Zhu, Ziyang Jia, Yijie Li, Zairan Wang, Boyu Sun, Qianxu Jin, Shiyang Zhang, Zongmao Zhao, Liqiang Liu

    Published 2025-02-01
    “…Abstract Sphingosine kinase 1 (SPHK1) is a member of the SPHK family, enzymes essential for the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P). …”
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  9. 1829

    Methyltransferase-like 7B participates in bladder cancer via ACSL3 m6A modification in a ferroptosis manner by Jiani He, Changming Dong, Xiandong Song, Zhongkai Qiu, Hao Zhang, Yuanjun Jiang, Tao Liu, Xiaojun Man

    Published 2025-01-01
    “…Considering that ferroptosis is emerging as a therapeutic target for cancer, and the possible relationship between METTL7B and antioxidant enzymes. We, here, examined that ectopic METTL7B expression abolished ferroptosis markers in cells raised by Erastin treatment, including the production of lipid ROS, the increased cellular iron and MDA content, the decreased gene expression of ACSL3, FANCD2, and FADS2, as well as the mitochondrial injury observed by electron microscopy. …”
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  10. 1830

    Protective and Ameliorative Effects of Hydroethanolic Extract of Piper nigrum (L.) Stem against Antiretroviral Therapy-Induced Hepatotoxicity and Dyslipidemia in Wistar Rats by Doreen Enyang, Mubo A. Sonibare, Armelle D. Tchamgoue, Lauve R. Y. Tchokouaha, Fanta S. Yadang, Gael N. Nfor, Christelle W. Kom, Patrick D. H. Betote, Cedric F. Tchinda, Steveng S. K. Tiogo, Gabriel A. Agbor

    Published 2024-01-01
    “…Portions of the liver and kidneys were collected for histological evaluation, while liver homogenates were prepared from the rest to measure antioxidant enzymes. PNS possessed in vitro cytotoxic, antioxidant, and anti-inflammatory activities. …”
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    Article
  11. 1831

    Severe Obesity in Women Can Lead to Worse Memory Function and Iron Dyshomeostasis Compared to Lower Grade Obesity by Jessica M. V. Pino, Vitória F. Silva, Marcos Mônico-Neto, Danielle C. Seva, Melissa Y. Kato, July N. Alves, Gabriela C. Pereira, Hanna Karen M. Antunes, Thales D. Galvao, Lia R. A. Bitterncourt, Sergio Tufik, Lysien I. Zambrano, Ana R. Dâmaso, Lila M. Oyama, David Thivel, Raquel M. S. Campos, Kil S. Lee

    Published 2023-01-01
    “…This is a cross-sectional study, in which 45 females with BMI varying from 32.8 to 51.9 kg/m2 completed a set of 4 cognitive tests (verbal paired-associate test, stroop color, digit span, and Toulouse–Pieron cancellation test) and their plasma metabolites, enzymes, and hormones related to glycemia, dyslipidemia, and liver function, as well as the biomarkers of iron status, were concomitantly analyzed. …”
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  12. 1832

    Comparative transcriptome analysis on candidate genes involved in lipid biosynthesis of developing kernels for three walnut cultivars in Xinjiang by Wenqiang Wang, Hao Wen, Qiang Jin, Wenjun Yu, Gen Li, Minyu Wu, Hongjin Bai, Lirong Shen, Cuiyun Wu

    Published 2022-09-01
    “…We identified 126 candidate genes including 64 genes for FA de novo synthesis, 45 genes for triacylglycerol assembly, and 17 genes for oil bodies involved in lipid biosynthesis by RNA-sequencing. Ten key enzymes including ACCase, LACS6, LACS8, SAD, FAD2, FAD3, LPAAT1, DGAT2, PDAT2, and PLC encoded by 19 genes were highly associated with lipid biosynthesis. …”
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  13. 1833

    Enterocytozoon bieneusi Identification Using Real-Time Polymerase Chain Reaction and Restriction Fragment Length Polymorphism in HIV-Infected Humans from Kinsh... by Roger Wumba, Menotti Jean, Longo-Mbenza Benjamin, Mandina Madone, Kintoki Fabien, Zanga Josué, Sala Jean, Kendjo Eric, Guillo-Olczyk AC, Thellier Marc

    Published 2012-01-01
    “…PCRRFLP generated with two restriction enzymes (Nla III and Fnu 4HI) in PCR-amplified ITS products for classifying strains into different lineages. …”
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  14. 1834

    Metabolic reprogramming in cancer: Mechanisms and therapeutics by Shiqi Nong, Xiaoyue Han, Yu Xiang, Yuran Qian, Yuhao Wei, Tingyue Zhang, Keyue Tian, Kai Shen, Jing Yang, Xuelei Ma

    Published 2023-04-01
    “…These metabolic pathways have complex mechanisms and involve the coordination of various signaling molecules, proteins, and enzymes, which increases the resistance of tumor cells to traditional antitumor therapies. …”
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    Article
  15. 1835

    Structural insights into dynamics of the BMV TLS aminoacylation by Wen Yang, Ran Yi, Jing Yao, Yongxiang Gao, Shanshan Li, Qingguo Gong, Kaiming Zhang

    Published 2025-02-01
    “…The dynamic changes also include a more compact arrangement in the catalytic center of TyrRS and the insertion of 3’ CCA end into the enzyme’s active site, facilitating two-steps aminoacylation. …”
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  16. 1836

    Gelatin/PLA-loaded gold nanocomposites synthesis using Syzygium cumini fruit extract and their antioxidant, antibacterial, anti-inflammatory, antidiabetic and anti-Alzheimer’s acti... by Manickam Rajkumar, S. I. Davis Presley, Nathiya Thiyagarajulu, Koyeli Girigoswami, Gopalarethinam Janani, Chinnaperumal Kamaraj, Bharathi Madheswaran, Bhupendra Prajapati, Nemat Ali, Mohammad Rashid Khan

    Published 2025-01-01
    “…The anti-Alzheimer activity was confirmed by inhibition of the AChE (76.37 ± 1.18%) and BChE (85.94 ± 1.38%) enzymes. In vivo studies of zebrafish embryos showed that Ge/PLA/AuNCs have excellent biocompatibility and nontoxicity. …”
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    Article
  17. 1837

    CD137 Signaling Promotes Endothelial Apoptosis by Inhibiting Nrf2 Pathway, and Upregulating NF-κB Pathway by Tianxin Geng, Yang Yan, Yue Zhang, Liangjie Xu, Guangyao Zang, Jin Chuan Yan

    Published 2020-01-01
    “…Confocal microscopy and Western blot analysis showed that the nuclear translocation of Nrf2 in the agonist-CD137 group was significantly inhibited, and the expression of its downstream antioxidant enzymes was also decreased when compared with control. …”
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  18. 1838
  19. 1839

    Health benefits of algae and marine-derived bioactive metabolites for modulating ulcerative colitis symptoms by Najmeh Oliyaei, Saghar Zekri, Aida Iraji, Alireza Oliyaei, Romina Tanideh, Nadiar M. Mussin, Amin Tamadon, Nader Tanideh

    Published 2025-02-01
    “…It has been reported that algal sulfated polysaccharides, peptides, pigments, polyphenols, and marine oil are useful for controlling ulcerative colitis via different pathways including modulating of TNF-α and other related inflammatory cytokines secretion, increasing the antioxidant enzymes [superoxide dismutase (SOD) and catalase(CAT)] activities, reduction of myeloperoxidase (MPO) activity and malondialdehyde (MDA) production, improving the intestinal barrier function and repairing histological damage in the colon. …”
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  20. 1840

    Domestic sewage irrigation on dynamics of nutrients and heavy metals in soil and wheat (Triticum aestivum L.) production by S. R. Salakinkop, C. S. Hunshal

    Published 2024-02-01
    “…Enhanced activity of dehydrogenase and phosphatase enzymes and organic carbon in sewage-irrigated field contributed more to available nutrient pool of soil. …”
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