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  1. 1621

    Phosphodiesterase 10A Is a Mediator of Osteogenic Differentiation and Mechanotransduction in Bone Marrow-Derived Mesenchymal Stromal Cells by Sigrid Müller-Deubert, Carolin Ege, Melanie Krug, Jutta Meißner-Weigl, Maximilian Rudert, Oliver Bischof, Franz Jakob, Regina Ebert

    Published 2020-01-01
    “…The second messengers cAMP and cGMP are degraded by phosphodiesterase isoenzymes (PDE), but the role of these enzymes during osteogenic differentiation or mechanotransduction remains unclear. …”
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  2. 1622

    Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature by Syed Muhammad Ali, Nissar Ahmed Shaikh, Zia Aftab, Ejaz Latif, Muhammad Sameer, Muhammad Burhan Khan, Mohannad Al-Tarakji

    Published 2020-01-01
    “…Case. 31-year-old female, one week after delivery, presented to the emergency department with abdominal pain, nausea and vomiting, tenderness in the epigastrium, and raised pancreatic enzymes. Ultrasound (USG) showed bulky pancreas with gallstones. …”
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  3. 1623

    Anti-Inflammatory Property of the Ethanol Extract of the Root and Rhizome of Pogostemon cablin (Blanco) Benth by Chu-Wen Li, Xiao-Li Wu, Xiao-Ning Zhao, Zu-Qing Su, Hai-Ming Chen, Xiu-Fen Wang, Xiao-Jun Zhang, Hui-Fang Zeng, Jian-Nan Chen, Yu-Cui Li, Zi-Ren Su

    Published 2013-01-01
    “…Preliminary mechanism studies demonstrated that ERP decreased the level of MPO and MDA, increased the activities of anti-oxidant enzymes (SOD, GPx, and GRd), attenuated the productions of TNF-α, IL-1β, IL-6, PGE2 and NO, and suppressed the activities of COX-2 and iNOS. …”
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  4. 1624

    The proposed protein and carbohydrate ingredients and the acceptance of moist feed by newly hatched Bigfin reef squid (Sepioteuthis lessoniana) by Natthawut Chanlek, Jirapan Satjarak, Yuzuru Ikeda, Nutt Nuntapong, Karun Thongprajukaew

    Published 2025-03-01
    “…Here, thirty sources of protein and seven of carbohydrate were tested for in vitro digestibility using digestive enzymes from viscera of Bigfin reef squid. Suitable protein ingredients included the meat of blue swimming crab, catfish, emperor fish, Indian anchovy, Indian mackerel, Nile tilapia, Pacific white shrimp, striped catfish, trash fish and yellow-stripe scad. …”
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  5. 1625

    Risk factors for hepatocellular carcinoma: an umbrella review of systematic review and meta-analysis by Jie Wang, Kaijie Qiu, Songsheng Zhou, Yichao Gan, Keting Jiang, Donghuan Wang, Haibiao Wang

    Published 2025-12-01
    “…Smoking, obesity, non-alcoholic fatty liver disease, diabetes, low platelet, elevated liver enzymes and liver fluke infection increase HCC risk, while coffee consumption, a healthy diet, and bariatric surgery lower it. …”
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  6. 1626

    Biological factors controlling starch digestibility in human digestive system by Cheng Li, Yiming Hu, Songnan Li, Xueer Yi, Shuaibo Shao, Wenwen Yu, Enpeng Li

    Published 2023-03-01
    “…Main biological factors are summarized as oral mastication and salivation, gastric emptying and motility, small intestinal enzymes and motility, large intestinal resistant starch (RS)-microbiota interactions and gut-brain feedback control, as well as glucose adsorption and hormonal feedback control. …”
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  7. 1627

    Hepatitis B virus hijacks MRE11-RAD50-NBS1 complex to form its minichromosome. by Kaitao Zhao, Jingjing Wang, Zichen Wang, Mengfei Wang, Chen Li, Zaichao Xu, Qiong Zhan, Fangteng Guo, Xiaoming Cheng, Yuchen Xia

    Published 2025-01-01
    “…These findings provide insights into how HBV hijacks host enzymes to establish chronic infection and reveal new therapeutic opportunities.…”
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  8. 1628

    Effects of Pioglitazone on Nonalcoholic Fatty Liver Disease in the Absence of Constitutive Androstane Receptor Expression by Hwa Young Ahn, Hwan Hee Kim, Ji-Yeon Hwang, Changhun Park, Bo Youn Cho, Young Joo Park

    Published 2018-01-01
    “…Pioglitazone is metabolized by multiple cytochrome P450 (CYP) enzymes, which are regulated by the xenobiotic receptor constitutive androstane receptor (CAR). …”
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  9. 1629

    Differential expression and localization of expansins in Arabidopsis shoots: implications for cell wall dynamics and drought tolerance by Darina Balkova, Katerina Mala, Jan Hejatko, Jan Hejatko, Klara Panzarova, Lamis Abdelhakim, Barbora Pleskacova, Marketa Samalova, Marketa Samalova

    Published 2025-02-01
    “…Overexpression of EXPA1 resulted in pronounced changes in CW-related gene expression, particularly during early stages of induction, including the upregulation of other expansins and CW-modifying enzymes. The induced EXPA1 line also displayed significant morphological changes in shoots, including smaller plant size, delayed senescence, and structural alterations in vascular tissues. …”
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  10. 1630
  11. 1631

    Impact of predictive selection of LbCas12a CRISPR RNAs upon on‐ and off‐target editing rates in soybean by Linda Rymarquis, Chenxi Wu, Diane Hohorst, Miguel Vega‐Sanchez, Thomas E. Mullen, Vijetha Vemulapalli, Douglas R. Smith

    Published 2024-08-01
    “…Abstract Clustered regularly interspaced short palindromic repeats (CRISPR) technology has revolutionized creating targeted genetic variation in crops. Although CRISPR enzymes have been reported to have high sequence‐specificity, careful design of the editing reagents can also reduce unintended edits at highly homologous sites. …”
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  12. 1632

    Promising LOX proteins for cartilage-targeting osteoarthritis therapy by Luca Morici, Eric Allémann, Olivier Jordan, Ines Nikolić

    Published 2025-02-01
    “…Finally, lysyl oxidase and lysyl oxidase-like are enzymes expressed intracellularly (in chondrocytes' cytoplasm) involved in elastin biosynthesis and collagen cross-linking in cartilage extracellular matrix. …”
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  13. 1633

    Research note: Increased lipid accumulation within broiler preadipocytes during differentiation in vitro at atmospheric oxygen tension by Jéssica Moraes Cruvinel, Elizabeth S. Greene, Rachel W. Read, Kichoon Lee, Sami Dridi, Paula R. Chen

    Published 2025-01-01
    “…Abundance of glutathione peroxidase 4 (GPX4) was increased in all the differentiation cultures compared to the controls, regardless of oxygen tension; however, differences in the abundance of other antioxidant enzymes were not observed. Overall, exposure to atmospheric oxygen tension promotes lipid accumulation within chicken preadipocytes, which may need to be considered when developing in vitro models of this process.…”
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  14. 1634

    Multi-stage structure-based virtual screening approach combining 3D pharmacophore, docking and molecular dynamic simulation towards the identification of potential selective PARP-1... by Mahmoud A. El Hassab, Wagdy M. Eldehna, Ghaneya S. Hassan, Sahar M. Abou-Seri

    Published 2025-02-01
    “…Abstract Presently, humanity is confronted with a range of diseases that have high death rates, especially those linked to cancerous growths. Several enzymes and proteins have been discovered as highly attractive targets for cancer treatment. …”
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  15. 1635

    Split Application of Potassium Reduces Rice Chalkiness by Regulating Starch Accumulation Process Under High Temperatures by Xinyue Zhang, Youfa Li, Junjie Dong, Yuanze Sun, Haowei Fu

    Published 2025-01-01
    “…Similarly, the gene expression levels of enzymes involved in this process were decreased by 3.52–24.12% at 5 DAA but increased by 8.61–30.00% at 20 DAA by the split application of K fertilizer. …”
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  16. 1636

    Assessment of scenarios for intensifying pasture management and grazing in fragile micro-watersheds of high Andean mountains by Jorge Eduardo Grijalva Olmedo, Paola Mercedes Palate Moreta, Roy Roger Vera-Vélez, Raúl Armando Ramos Veintimilla, Jean-François Tourrand, Arnulfo Portilla Narváez

    Published 2025-02-01
    “…In sheep serum, Ca, P, and Mg profiles, and the activity of AST, ALT, and FA enzymes were analyzed. The data were analyzed using ANOVA and Tukey 5% as a means comparison test. …”
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  17. 1637

    Influence of a lignification and mineralization of leaf tissues on resistance to a brown rust in common wheat plants by A. A. Konovalov, I. K. Shundrina, E. V. Karpova, I. V. Eltsov, E. A. Orlova, N. P. Goncharov

    Published 2017-11-01
    “…Aromatic substances in plant tissues can have protective effect against fungal diseases. One of the key enzymes in aromatic metabolism of plants, CAD (cinnamyl-alcohol dehydrogenase, dehydrogenase of cinnamyl alcohol; EC 1.1.1.195), at a number of species of plants exerts impact on the content of aromatic substances and on protective properties of tissues from fungal infections. …”
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  18. 1638

    Mechanisms of phenolic biosynthesis induced by ultrasound stress in fresh-cut red cabbages based on energy metabolism analysis by Ningning Ouyang, Chen Hong, Lina Guo, Xinyan Zhang, Wenjuan Qu, Haile Ma

    Published 2025-09-01
    “…The effects of exogenous adenosine triphosphate (ATP) and 2,4-dinitrophenol (DNP) on the phenolic biosynthesis and antioxidant enzymes of fresh-cut red cabbages were also studied. …”
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  19. 1639

    Molecular Epidemiology and Antimicrobial Resistance of Extended-Spectrum β-Lactamase (ESBL)-Producing Klebsiella pneumoniae in Retail Cattle Meat by Nasrin Akter Liza, Hemayet Hossain, Md. Shahidur Rahman Chowdhury, Jarin Al Naser, Rayhan Mahmud Lasker, Asikur Rahman, Md. Ariful Haque, Md. Al Mamun, Md. Mukter Hossain, Md. Mahfujur Rahman

    Published 2024-01-01
    “…Antimicrobial susceptibilities were assessed using disk diffusion in accordance with the Clinical and Laboratory Standards Institute (CLSI, 2020) guidelines. Genes encoding ESBL enzymes were detected by the double-disk synergy test (DDST) and multiplex PCR. …”
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  20. 1640

    Hemoprotein dalam Tubuh Manusia by Husnil Kadri

    Published 2012-07-01
    “…Base on Fe ion state in heme group, hemoproteins are divided into: (1) Hemoproteins have ion Fe2+ state that can bind oxygen, such as hemoglobin, myoglobin, neuroglobin, and cytoglobin. (2) Hemoproteins have ion Fe3+ state that act as oxidoreductase enzymes, such as cytochrome P450, cytochromes in oxidative phosphorylation, catalase, tryptophan pyrolase, and NO synthase. …”
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