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1621
Phosphodiesterase 10A Is a Mediator of Osteogenic Differentiation and Mechanotransduction in Bone Marrow-Derived Mesenchymal Stromal Cells
Published 2020-01-01“…The second messengers cAMP and cGMP are degraded by phosphodiesterase isoenzymes (PDE), but the role of these enzymes during osteogenic differentiation or mechanotransduction remains unclear. …”
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1622
Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature
Published 2020-01-01“…Case. 31-year-old female, one week after delivery, presented to the emergency department with abdominal pain, nausea and vomiting, tenderness in the epigastrium, and raised pancreatic enzymes. Ultrasound (USG) showed bulky pancreas with gallstones. …”
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1623
Anti-Inflammatory Property of the Ethanol Extract of the Root and Rhizome of Pogostemon cablin (Blanco) Benth
Published 2013-01-01“…Preliminary mechanism studies demonstrated that ERP decreased the level of MPO and MDA, increased the activities of anti-oxidant enzymes (SOD, GPx, and GRd), attenuated the productions of TNF-α, IL-1β, IL-6, PGE2 and NO, and suppressed the activities of COX-2 and iNOS. …”
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1624
The proposed protein and carbohydrate ingredients and the acceptance of moist feed by newly hatched Bigfin reef squid (Sepioteuthis lessoniana)
Published 2025-03-01“…Here, thirty sources of protein and seven of carbohydrate were tested for in vitro digestibility using digestive enzymes from viscera of Bigfin reef squid. Suitable protein ingredients included the meat of blue swimming crab, catfish, emperor fish, Indian anchovy, Indian mackerel, Nile tilapia, Pacific white shrimp, striped catfish, trash fish and yellow-stripe scad. …”
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1625
Risk factors for hepatocellular carcinoma: an umbrella review of systematic review and meta-analysis
Published 2025-12-01“…Smoking, obesity, non-alcoholic fatty liver disease, diabetes, low platelet, elevated liver enzymes and liver fluke infection increase HCC risk, while coffee consumption, a healthy diet, and bariatric surgery lower it. …”
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1626
Biological factors controlling starch digestibility in human digestive system
Published 2023-03-01“…Main biological factors are summarized as oral mastication and salivation, gastric emptying and motility, small intestinal enzymes and motility, large intestinal resistant starch (RS)-microbiota interactions and gut-brain feedback control, as well as glucose adsorption and hormonal feedback control. …”
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1627
Hepatitis B virus hijacks MRE11-RAD50-NBS1 complex to form its minichromosome.
Published 2025-01-01“…These findings provide insights into how HBV hijacks host enzymes to establish chronic infection and reveal new therapeutic opportunities.…”
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1628
Effects of Pioglitazone on Nonalcoholic Fatty Liver Disease in the Absence of Constitutive Androstane Receptor Expression
Published 2018-01-01“…Pioglitazone is metabolized by multiple cytochrome P450 (CYP) enzymes, which are regulated by the xenobiotic receptor constitutive androstane receptor (CAR). …”
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1629
Differential expression and localization of expansins in Arabidopsis shoots: implications for cell wall dynamics and drought tolerance
Published 2025-02-01“…Overexpression of EXPA1 resulted in pronounced changes in CW-related gene expression, particularly during early stages of induction, including the upregulation of other expansins and CW-modifying enzymes. The induced EXPA1 line also displayed significant morphological changes in shoots, including smaller plant size, delayed senescence, and structural alterations in vascular tissues. …”
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1630
Effect of Microwave Treatment on Microbial Contamination of Honeys and on Their Physicochemical and Thermal Properties
Published 2015-06-01“…Diastase and glucose-oxidase enzymes were totally inactivated by microwave treatment.…”
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1631
Impact of predictive selection of LbCas12a CRISPR RNAs upon on‐ and off‐target editing rates in soybean
Published 2024-08-01“…Abstract Clustered regularly interspaced short palindromic repeats (CRISPR) technology has revolutionized creating targeted genetic variation in crops. Although CRISPR enzymes have been reported to have high sequence‐specificity, careful design of the editing reagents can also reduce unintended edits at highly homologous sites. …”
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1632
Promising LOX proteins for cartilage-targeting osteoarthritis therapy
Published 2025-02-01“…Finally, lysyl oxidase and lysyl oxidase-like are enzymes expressed intracellularly (in chondrocytes' cytoplasm) involved in elastin biosynthesis and collagen cross-linking in cartilage extracellular matrix. …”
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1633
Research note: Increased lipid accumulation within broiler preadipocytes during differentiation in vitro at atmospheric oxygen tension
Published 2025-01-01“…Abundance of glutathione peroxidase 4 (GPX4) was increased in all the differentiation cultures compared to the controls, regardless of oxygen tension; however, differences in the abundance of other antioxidant enzymes were not observed. Overall, exposure to atmospheric oxygen tension promotes lipid accumulation within chicken preadipocytes, which may need to be considered when developing in vitro models of this process.…”
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1634
Multi-stage structure-based virtual screening approach combining 3D pharmacophore, docking and molecular dynamic simulation towards the identification of potential selective PARP-1...
Published 2025-02-01“…Abstract Presently, humanity is confronted with a range of diseases that have high death rates, especially those linked to cancerous growths. Several enzymes and proteins have been discovered as highly attractive targets for cancer treatment. …”
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1635
Split Application of Potassium Reduces Rice Chalkiness by Regulating Starch Accumulation Process Under High Temperatures
Published 2025-01-01“…Similarly, the gene expression levels of enzymes involved in this process were decreased by 3.52–24.12% at 5 DAA but increased by 8.61–30.00% at 20 DAA by the split application of K fertilizer. …”
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1636
Assessment of scenarios for intensifying pasture management and grazing in fragile micro-watersheds of high Andean mountains
Published 2025-02-01“…In sheep serum, Ca, P, and Mg profiles, and the activity of AST, ALT, and FA enzymes were analyzed. The data were analyzed using ANOVA and Tukey 5% as a means comparison test. …”
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1637
Influence of a lignification and mineralization of leaf tissues on resistance to a brown rust in common wheat plants
Published 2017-11-01“…Aromatic substances in plant tissues can have protective effect against fungal diseases. One of the key enzymes in aromatic metabolism of plants, CAD (cinnamyl-alcohol dehydrogenase, dehydrogenase of cinnamyl alcohol; EC 1.1.1.195), at a number of species of plants exerts impact on the content of aromatic substances and on protective properties of tissues from fungal infections. …”
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1638
Mechanisms of phenolic biosynthesis induced by ultrasound stress in fresh-cut red cabbages based on energy metabolism analysis
Published 2025-09-01“…The effects of exogenous adenosine triphosphate (ATP) and 2,4-dinitrophenol (DNP) on the phenolic biosynthesis and antioxidant enzymes of fresh-cut red cabbages were also studied. …”
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1639
Molecular Epidemiology and Antimicrobial Resistance of Extended-Spectrum β-Lactamase (ESBL)-Producing Klebsiella pneumoniae in Retail Cattle Meat
Published 2024-01-01“…Antimicrobial susceptibilities were assessed using disk diffusion in accordance with the Clinical and Laboratory Standards Institute (CLSI, 2020) guidelines. Genes encoding ESBL enzymes were detected by the double-disk synergy test (DDST) and multiplex PCR. …”
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1640
Hemoprotein dalam Tubuh Manusia
Published 2012-07-01“…Base on Fe ion state in heme group, hemoproteins are divided into: (1) Hemoproteins have ion Fe2+ state that can bind oxygen, such as hemoglobin, myoglobin, neuroglobin, and cytoglobin. (2) Hemoproteins have ion Fe3+ state that act as oxidoreductase enzymes, such as cytochrome P450, cytochromes in oxidative phosphorylation, catalase, tryptophan pyrolase, and NO synthase. …”
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