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  1. 1481

    Gambaran Pemeriksaan Kadar SGOT, SGPT, Ureum dan Kreatinin Pasien Covid-19 dengan dan tanpa Komorbid by Rachmi Fadillah, Ellyza Nasrul, Tuty Prihandani

    Published 2021-09-01
    “…Coronavirus disease (COVID-19) causes damage through mechanisms: cytotoxic to the bile duct, liver and renal tubular epithelial cells; severe inflammatory response due to excessive pro-inflammatory cytokines (cytokine storm); tissue anoxia; and drug-induced liver and kidney damage. AST and ALT enzymes are used to determine liver damage, while kidney damage is examined from increased urea and creatinine levels. …”
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  2. 1482

    Spontaneous Complete Regression of Colon Cancer Liver Metastases in a Lung Transplant Patient: A Case Report by Koen Zwart, Dieuwertje Ruigrok, Magda de Graaf-Bos, Roel Goldschmeding, Miriam Koopman, Guus M. Bol

    Published 2023-01-01
    “…A 59-year-old female was admitted with fever, general discomfort, and elevated liver enzymes. She had received a single lung transplant, five years prior, for end-stage chronic obstructive pulmonary disease. …”
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  3. 1483

    Liquefied Petroleum Gas Poisoning in a Child: A Case Report from a Low-Middle Income Country by Abid Jamali, Latif Shamasuddin, Aimen Yunus, Nadeem Ullah Khan

    Published 2024-12-01
    “…Serial monitoring of cardiac enzymes and electrocardiograms is crucial to prevent lethal arrhythmias and cardiac dysfunction.…”
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  4. 1484

    A Structural Effect of the Antioxidant Curcuminoids on the Aβ(1–42) Amyloid Peptide by Angelo Santoro, Antonio Ricci, Manuela Rodriquez, Michela Buonocore, Anna Maria D’Ursi

    Published 2025-01-01
    “…Antioxidants like curcumin, a derivative of Curcuma longa, help mitigate ER stress by scavenging ROS and enhancing antioxidant enzymes. Furthermore, evidence in the literature highlights the effect of curcumin on the secondary structure of Aβ(1–42). …”
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  5. 1485

    Recovery of Prenatal Baicalein Exposure Perturbed Reproduction by Postnatal Exposure of Testosterone in Male Mice by Sridevi Vaadala, Naveen Ponneri, Venkata Shashank Karanam, Sri Bhashyam Sainath, Pamanji Sreenivasuala Reddy, Ramachandra Reddy Pamuru, Arifullah Mohammed

    Published 2020-01-01
    “…A downward trend was observed in testicular steroidogenic marker enzymes (3β- and 17β-steroid dehydrogenases) and serum testosterone, whereas increase in serum titers of FSH and LH along with altered the testicular histology. …”
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  6. 1486

    Pretreatment of Small-for-Size Grafts In Vivo by γ-Aminobutyric Acid Receptor Regulation against Oxidative Stress-Induced Injury in Rat Split Orthotopic Liver Transplantation by Tomohide Hori, Shinji Uemoto, Lindsay B. Walden, Feng Chen, Ann-Marie T. Baine, Toshiyuki Hata, Justin H. Nguyen

    Published 2013-01-01
    “…Immunohistological assessment for apoptotic induction and western blotting for 4-hydroxynonenal, ataxia-telangiectasia mutated kinase (ATM), histone H2AX, phosphatidylinositol-3 kinase (PI3K), Akt, and free radical scavenging enzymes were performed. Results. Pretreatment by GABAR showed improvement in survival, histopathological assessment, and biochemical tests. …”
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  7. 1487

    Ulcerative Colitis Preceding Asymptomatic Wilson’s Disease: A Case Report and Literature Review by Jun Kunizaki, Yuko Yoto, Yoshinobu Nagaoka, Akira Ishii, Tomoe Kazama, Kohei Wagatsuma, Noriyuki Akutsu, Aki Ishikawa, Toju Tanaka, Shintaro Sugita, Takeshi Tsugawa, Hiroshi Nakase

    Published 2025-01-01
    “…An 11-year-old girl with quiescent ulcerative colitis had sustained elevation of liver enzymes. Although she had no clinical symptoms suggestive of Wilson’s disease, such as Kayser–Fleischer rings, laboratory data showed decreased serum copper and ceruloplasmin levels and increased urinary copper excretion. …”
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  8. 1488

    Beta-Thalassemia Major and Female Fertility: The Role of Iron and Iron-Induced Oxidative Stress by Paraskevi Roussou, Nikolaos J. Tsagarakis, Dimitrios Kountouras, Sarantis Livadas, Evanthia Diamanti-Kandarakis

    Published 2013-01-01
    “…Meanwhile, a significant prooxidants/antioxidants imbalance with subsequent increased (OS) exists in patients with BTM, which is mainly caused by tissue injury due to overproduction of free radicals by secondary iron overload, but also due to alteration in serum trace elements and antioxidant enzymes. Not only using the appropriate antioxidants, essential trace elements, and minerals, but also regulating the advanced glycation end products, could probably reduce the extent of oxidative damage and related complications and retrieve BTM women’s infertility.…”
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  9. 1489

    Comparative Study on the Effects of Four Plant Protein Sources on the Liver and Intestinal Health of Largemouth Bass, Micropterus salmoides by Shibin Yao, Wenjian Li, Chunfang Cai, Chengrui Wang, Jia Kang, Honglin Hu, Ping Wu, Xiamin Cao, Yuantu Ye

    Published 2024-01-01
    “…The contents of total bile acid, lipid, and collagen in the liver were increased, and the mRNA expression levels of genes encoding inflammatory factors and enzymes involved in de novo fatty acid synthesis and bile acid synthesis were upregulated. …”
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  10. 1490

    The Function of SUMOylation and Its Role in the Development of Cancer Cells under Stress Conditions: A Systematic Review by Qi Zhao, Ying Ma, Zugui Li, Kexin Zhang, Minying Zheng, Shiwu Zhang

    Published 2020-01-01
    “…SUMOylation is a dynamic process finely regulated by SUMOylation enzymes and proteases to maintain a balance between SUMOylation and deSUMOylation. …”
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  11. 1491

    Value of alpha smooth muscle actin (αSMA) and inducible nitric oxide synthase (iNOS) in oral squamous cell carcinoma (OSCC): An immunohistochemical approach to tumor stroma categor... by Heba E.M. Youssef, Basant Hamdy AbouZaid

    Published 2025-03-01
    “…Inducible nitric oxide synthase (iNOS) is one of the main enzymes producing the free radical, nitric oxide in response to various stimuli. …”
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  12. 1492

    Assessment of Serum Dynamic Thiol/Disulfide Homeostasis and Oxidative/Nitrosative Stress in Patients with Crohn’s Disease by Ancel Aysun Bağdaş, Sezgin Barutçu, Ahmet Saracaloğlu, Abdullah Tuncay Demiryürek

    Published 2025-02-01
    “…Conclusion: Our results showed increased serum NO levels and decreased antioxidant enzymes, particularly during the active phase of CD. …”
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  13. 1493

    Improvement of Fish Growth and Metabolism by Oligosaccharide Prebiotic Supplement by Wei Xu, Charles Greg Lutz, Christopher M. Taylor, Miriam Contin Ortega

    Published 2022-01-01
    “…The application of XOS and GOS also elevated the production of glutathione-related enzymes and the enzymatic activity of glutathione peroxidase (GPX), indicating the enhancement of antioxidation processes in fish. …”
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  14. 1494

    Improving Goat Meat (Longissimus Muscle) Tenderization by Using Moringa Oleifera Leaves by Hunin AbdElwhab Mohamed Tasnim, Sumarmono Juni, Fatoni Amin, Zeinalabdeen Abdelgadir Frah Amani, Fadhlurrohman Irfan, Muhammad Yusuf Hassan

    Published 2025-01-01
    “…The present results suggest that Moringa oleifera seems to be a promising source of exogenous enzymes for meat tenderization.…”
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  15. 1495

    Novel tetracycline hybrids: synthesis, characterization, docking studies and in-vitro evaluation of antibacterial activity by Mansi Shah, Bhanubhai Suhagia, Sunita Goswami, Sneha Sagar, Arpit Patwari

    Published 2025-01-01
    “…Molecular docking was carried out in order to predict the binding affinity of these compounds to various bacterial enzymes and known protein targets and to establish the structure–activity relationships. …”
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  16. 1496

    Adaptation of Archaeal Communities to Summer Hypoxia in the Sediment of Bohai Sea by Xiaoxiao Guo, Yanying Li, Guisheng Song, Liang Zhao, Jing Wang

    Published 2025-01-01
    “…The enrichment of specific nitrogen transformation enzymes showed the potential for nitrogen fixation and removal, which might contribute to the balance of N budget and thus facilitate the ecological restoration under eutrophication in Bohai Sea. …”
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  17. 1497

    Starch metabolism in potato <i>Solanum tuberosum</i> L. by E. M. Sergeeva, K. T. Larichev, E. A. Salina, A. V. Kochetov

    Published 2022-06-01
    “…It is a complex process, requiring the orchestrated work of many enzymes, transporter and targeting proteins, transcription factors, and other regulators. …”
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  18. 1498

    A Snake Venom-Secreted Phospholipase A2 Induces Foam Cell Formation Depending on the Activation of Factors Involved in Lipid Homeostasis by Elbio Leiguez, Karina Cristina Giannotti, Mariana do Nascimento Viana, Márcio Hideki Matsubara, Cristina Maria Fernandes, José Maria Gutiérrez, Bruno Lomonte, Catarina Teixeira

    Published 2018-01-01
    “…Pharmacological interventions evidenced that PPAR-γ, PPAR-β/δ, and CD36 as well as the endoplasmic reticulum enzymes ACAT and DGAT are essential for LD formation. …”
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  19. 1499

    Discovery of two novel Flavobacterium species with potential for complex polysaccharide degradation by Xu-Dong Lian, Yong Guan, Yue Jiang, Dong-Heui Kwak, Mi-Kyung Lee, Zhun Li

    Published 2025-01-01
    “…Additional investigations using the dbCAN and dbCAN-PUL databases identified the presence of carbohydrate-hydrolyzing enzymes (CAZymes) and polysaccharide utilization loci (PULs) within these strains, suggesting their potential to degrade various polysaccharides. …”
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  20. 1500

    Ester derivatives of Dictyostelium differentiation-inducing factors exhibit antibacterial activity, possibly via a prodrug-like function by Katsunori Takahashi, Haruhisa Kikuchi, Takehiro Nishimura, Hirotaka Ishigaki, Yusuke Miura, Ayuko Takahashi, Yuzuru Kubohara

    Published 2025-01-01
    “…The results suggest that suitable ester modifications could enhance the in vivo antibacterial potential of DIF compounds, particularly if they can bypass HSA binding and be activated by bacterial enzymes.…”
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